Alexandra Maștaleru, Sabina Alexandra Cojocariu, Andra Oancea, Maria Magdalena Leon Constantin, Mihai Roca, Ioana Mădălina Zota, Irina Abdulan, Cristina Rusu, Roxana Popescu, Lucian Mihai Antoci, Cristian Gabriel Ciobanu, Alexandru Dan Costache, Elena Cojocaru, Florin Mitu
(1) Background: Familial hypercholesterolemia (FH) is one of the most prevalent inherited metabolic disorders. The purpose of the study was to investigate the role in cardiovascular disease (CVD) of PAI-1 , ACE , ApoB-100 , MTHFR A1298C , and C677T . (2) Methods: From a group of 1499 patients, we included 52 patients diagnosed with FH phenotype and 17 patients in a control group. (3) Results: Most of the FH patients had multiple comorbidities compared to the control group, such as atherosclerosis (48.1% vs...
March 9, 2022: Journal of Personalized Medicine