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JOURNAL ARTICLE
Debra Barrett Graham
Lead with the problem, never the intervention.
May 1, 2024: American Journal of Nursing
#22
JOURNAL ARTICLE
William D Marelich, Brandin Ali, Debra A Murphy, Marya T Schulte, Lisa Armistead
OBJECTIVE: The current study applied survival analysis to examine factors associated with nondisclosure of human immunodeficiency virus (HIV) serostatus among mothers living with HIV (MLH) who had participated in a cognitive-behavioral intervention to disclose their HIV status to their children. METHOD: Data were utilized from MLH in the intervention arm of the teaching, raising, and communicating with kids (TRACK; Schulte et al., 2021) trial focusing on serostatus disclosure/nondisclosure across four time points (baseline, 3, 9, and 15 months)...
April 25, 2024: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
#23
JOURNAL ARTICLE
Alicia Duval, Anne L Beatty-Martínez, Stamatoula Pasvanis, Arielle Crestol, Jamie Snytte, M Natasha Rajah, Debra A Titone
Menopause is associated with declines in cognitive control. However, there is individual variability in the slope of this decline. Recent work suggests that indices of cognitive control are mediated by communicative demands of the language environment. However, little is known about how the impact of bilingual experience generalizes across the lifespan, particularly in females who exhibit steeper cognitive decline due to increasing age and menopausal transition. Thus, we investigated whether diversity of language use in distinct communicative contexts modulated the effects of aging and menopause on cognitive control in an adult lifespan sample of healthy females...
April 25, 2024: Journal of Experimental Psychology. General
#24
JOURNAL ARTICLE
Galen Conti, Edward P Notari, Roger Y Dodd, Debra Kessler, Brian Custer, Roberta Bruhn, Rita Reik, Hong Yang, Barbee I Whitaker, Susan L Stramer
BACKGROUND: The COVID-19 pandemic impacted the US blood supply. We compared blood donor demography and infectious disease prevalence before and during the pandemic using a large multicenter database. METHODS: Data were categorized as "Before COVID-19" (March 2018-February 2020) or "During COVID-19" (March 2020-February 2022). Donor demographics, donation frequency, and infectious marker prevalence of HIV, HBV, and HCV were compared for the two time periods. The odds of a donor testing positive for these infections among the two time periods were calculated using multivariable logistic regression...
April 25, 2024: Transfusion
#25
JOURNAL ARTICLE
Anna M Gorczyca, Richard A Washburn, Lauren T Ptomey, Matthew S Mayo, Ron Krebill, Debra K Sullivan, Cheryl A Gibson, Sarah Stolte, Joseph E Donnelly
INTRODUCTION: Rural living adults have higher rates of obesity compared with their urban counterparts and less access to weight management programs. Previous research studies have demonstrated clinically relevant weight loss in rural living adults who complete weight management programs delivered by university affiliated interventionists. However, this approach limits the potential reach, adoption, implementation, and maintenance of weight management programs for rural residents. Weight management delivered through rural health clinics by non-physician clinic associated staff, for example, nurses, registered dieticians, allied health professionals, etc...
April 2024: Obesity Science & Practice
#26
EDITORIAL
Jacqueline M McGrath, Debra H Brandon
No abstract text is available yet for this article.
October 1, 2023: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
#27
JOURNAL ARTICLE
Keith Weitz, Debra Kantner, Andrew Kessler, Haley Key, Judd Larson, Wanda Bodnar, Sameer Parvathikar, Lynn Davis, Nicole Robey, Philip Taylor, Florentino De la Cruz, Thabet Tolaymat, Nathan Weber, William Linak, Jonathan Krug, Lara Phelps
Per- and poly-fluoroalkyl substances (PFAS) are a class of synthetic chemicals known for their widespread presence and environmental persistence. Carbon-fluorine (C-F) bonds are major components among PFAS and among the strongest organic bonds, thus destroying PFAS may present significant challenge. Thermal treatment such as incineration is an effective and approved method for destroying many halogenated organic chemicals. Here, we present the results of existing studies and testing at combustion-based thermal treatment facilities and summarize what is known regarding PFAS destruction and mineralization at such units...
April 22, 2024: Science of the Total Environment
#28
JOURNAL ARTICLE
Fakiha Siddiqui, Debra Hoppensteadt, Walter Jeske, Eduardo Ramacciotti, Alfonso Tafur, Jawed Fareed
INTRODUCTION: Andexanet alfa (AA) - zhzo, recombinant coagulation factor Xa, is an approved antidote for oral Xa inhibitors (apixaban and rivaroxaban). Unfractionated heparin (UFH) is commonly used for therapeutic, interventional, and surgical indications. Protamine sulfate (PrSO4 ) is frequently used to neutralize UFH. This study aimed to investigate the comparative neutralization profiles of AA and PrSO4 for heparins of bovine, ovine, and porcine origin. MATERIALS AND METHODS: The neutralization effect of PrSO4 at 25 µg/ml and AA at 100 µg/ml was studied on an approximate surgical/interventional concentration of heparin by supplementing whole blood with each of the heparins at 25 µg/ml...
2024: Clinical and Applied Thrombosis/hemostasis
#29
JOURNAL ARTICLE
Marc A Woods, Debra Hampton, Chizimuzo T C Okoli, Janie Heath, Gwen Moreland
OBJECTIVE: The purpose of this pilot study was to evaluate the effect of a web-based education module on the knowledge, attitudes, and ratings of willingness to access help related to suicide prevention in psychiatric-mental health nurses. METHODS: A quasi-experimental pretest-posttest design was employed. Registered nurses from two academic health center units and a 239-bed Psychiatric Hospital were invited to participate. Scores on knowledge of suicide risk and prevention, attitudes, subjective norms, perceived behavioral control, and intent to seek help upon experiencing suicidal ideations were obtained before and after administering a 25-min web-based training...
April 23, 2024: Journal of the American Psychiatric Nurses Association
#30
JOURNAL ARTICLE
Shalina Nair, José E Rodríguez, Samantha Elwood, Elisabeth Wilson, Annamalai Ramanathan, Debra Stulberg, Belinda Vail, Kristen Rundell, C J Peek
PROBLEM: Equity, diversity, and inclusion (EDI) efforts have accelerated over the past several years, without a traditional guidebook that other missions often have. To evaluate progress over time, departments of family medicine are seeking ways to measure their current EDI state. Across the specialty, unity regarding which EDI metrics are meaningful is absent, and discordance even exists about what should be measured. APPROACH: This paper provides a general metrics framework, including a wide array of possibilities to consider measuring, for assessing individual departmental progress in this broad space...
April 16, 2024: Family Medicine
#31
JOURNAL ARTICLE
Katherine Raboin, Debra Ellis, Ginger Nichols, Marcia Hughes, Michael Brimacombe, Karen Rubin
The Connecticut Newborn Screening (NBS) Network, in partnership with the Connecticut Department of Public Health, strategically utilized the Epic electronic health record (EHR) system to establish registries for tracking long-term follow-up (LTFU) of NBS patients. After launching the LTFU registry in 2019, the Network obtained funding from the Health Resources and Services Administration to address the slow adoption by specialty care teams. An LTFU model was implemented in the three highest-volume specialty care teams at Connecticut Children's, involving an early childhood cohort diagnosed with an NBS-identified disorder since the formation of the Network in March 2019...
March 25, 2024: International Journal of Neonatal Screening
#32
JOURNAL ARTICLE
Jezid Miranda, Suellen Miller, Nikita Alfieri, Andre Lalonde, Edgar Ivan-Ortiz, Claudia Hanson, Margit Steinholt, Nandita Palshetkar, Harris Suharjono, Stefan Gebhardt, Jean-Paul Dossou, Debra Pascali-Bonaro, Bo Jacobsson, Pius Okong
OBJECTIVE: To demonstrate that successful health systems strengthening (HSS) projects have addressed disparities and inequities in maternal and perinatal care in low-income countries. METHODS: A comprehensive literature review covered the period between 1980 and 2022, focusing on successful HSS interventions within health systems' seven core components that improved maternal and perinatal care. RESULTS: The findings highlight the importance of integrating quality interventions into robust health systems, as this has been shown to reduce maternal and newborn mortality...
April 23, 2024: International Journal of Gynaecology and Obstetrics
#33
JOURNAL ARTICLE
Karen Hall, Jason Skues, Debra Kiegaldie
Preparing enrolled nurses (ENs) to effectively work with mental health consumers is crucial to meeting Australia's healthcare demands. This qualitative study aimed to explore various stakeholders' perceptions regarding the mental health knowledge, skills, and attributes (KSAs) required by ENs to engage with individuals experiencing mental health issues, thus guiding future training priorities. The sample comprised 44 participants including 18 students, 3 graduate ENs, 5 experienced ENs, 5 registered nurses (RNs), 4 nurse unit managers (NUMs), 5 teachers, and 5 consumers of mental health services...
April 23, 2024: International Journal of Mental Health Nursing
#34
JOURNAL ARTICLE
Nicholas Chapman, Joshua Greenwald, Jolee Suddock, Dong Xu, Alexander Markowitz, Maeve Humphrey, Jennifer A Cotter, Mark D Krieger, Debra Hawes, Jianling Ji
Integration of molecular data with histologic, radiologic, and clinical features is imperative for accurate diagnosis of pediatric central nervous system (CNS) tumors. Whole transcriptome RNA sequencing (RNAseq), a genome-wide and non-targeted approach, allows for the detection of novel or rare oncogenic fusion events that contribute to the tumorigenesis of a substantial portion of pediatric low- and high-grade glial and glioneuronal tumors. We present two cases of pediatric glioneuronal tumors occurring in the occipital region with a CLIP2::MET fusion detected by RNAseq...
April 22, 2024: Acta Neuropathologica Communications
#35
JOURNAL ARTICLE
Jonathan Z Pan, Zhanqiang Wang, Wei Sun, Peipei Pan, Wei Li, Yongtao Sun, Shoulin Chen, Amity Lin, Wulin Tan, Liangliang He, Jacob Greene, Virginia Yao, Lijun An, Rich Liang, Qifeng Li, Jessica Yu, Lingyi Zhang, Nikolaos Kyritsis, Xuan Duong Fernandez, Sara Moncivais, Esmeralda Mendoza, Pamela Fung, Gongming Wang, Xinhuan Niu, Qihang Du, Zhaoyang Xiao, Yuwen Chang, Peiyuan Lv, J Russell Huie, Abel Torres-Espin, Adam R Ferguson, Debra D Hemmerle, Jason F Talbott, Philip R Weinstein, Lisa U Pascual, Vineeta Singh, Anthony M DiGiorgio, Rajiv Saigal, William D Whetstone, Geoffrey T Manley, Sanjay S Dhall, Jacqueline C Bresnahan, Mervyn Maze, Xiangning Jiang, Neel S Singhal, Michael S Beattie, Hua Su, Zhonghui Guan
BACKGROUND: Although many molecules have been investigated as biomarkers for spinal cord injury (SCI) or ischemic stroke, none of them are specifically induced in central nervous system (CNS) neurons following injuries with low baseline expression. However, neuronal injury constitutes a major pathology associated with SCI or stroke and strongly correlates with neurological outcomes. Biomarkers characterized by low baseline expression and specific induction in neurons post-injury are likely to better correlate with injury severity and recovery, demonstrating higher sensitivity and specificity for CNS injuries compared to non-neuronal markers or pan-neuronal markers with constitutive expressions...
April 2024: Clinical and Translational Medicine
#36
JOURNAL ARTICLE
Thomas J Flotte, Stephanie A Derauf, Rachel K Byrd, Trynda N Kroneman, Debra A Bell, Lucas Stetzik, Seung-Yi Lee, Alireza Samiei, Steven N Hart, Joaquin J Garcia, Gillian Beamer, Thomas Westerling-Bui
CONTEXT.—: Artificial intelligence is a transforming technology for anatomic pathology. Involvement within the workforce will foster support for algorithm development and implementation. OBJECTIVE.—: To develop a supportive ecosystem that enables pathologists with variable expertise in artificial intelligence to create algorithms in a development environment with seamless transition to a production environment. RESULTS.—: The development team considered internal development and vended solutions...
April 23, 2024: Archives of Pathology & Laboratory Medicine
#37
Jing Liu, Federica Mosti, Hanzhi T Zhao, Jesus E Sotelo-Fonseca, Carla F Escobar-Tomlienovich, Davoneshia Lollis, Camila M Musso, Yiwei Mao, Abdull J Massri, Hannah M Doll, Andre M Sousa, Gregory A Wray, Ewoud Schmidt, Debra L Silver
Humans evolved an extraordinarily expanded and complex cerebral cortex, associated with developmental and gene regulatory modifications 1-3 . Human accelerated regions (HARs) are highly conserved genomic sequences with human-specific nucleotide substitutions. Although there are thousands of annotated HARs, their functional contribution to human-specific cortical development is largely unknown 4,5 . HARE5 is a HAR transcriptional enhancer of the WNT signaling receptor Frizzled8 (FZD8) active during brain development 6 ...
April 11, 2024: bioRxiv
#38
JOURNAL ARTICLE
Rhys Kraft, Mathew Mercuri, Natasha Clayton, Andrew Worster, Eric Mercier, Marcel Emond, Catherine Varner, Shelley L McLeod, Debra Eagles, Ian Stiell, David Barbic, Judy Morris, Rebecca Jeanmonod, Yoan K Kagoma, Ashkan Shoamanesh, Paul T Engels, Sunjay Sharma, Alexandra Papaioannou, Sameer Parpia, Ian Buchanan, Mariyam Ali, Kerstin de Wit
OBJECTIVE: Physicians vary in their computed tomography (CT) scan usage. It remains unclear how physician gender relates to clinical practice or patient outcomes. The aim of this study was to assess the association between physician gender and decision to order head CT scans for older emergency patients who had fallen. METHODS: This was a secondary analysis of a prospective observational cohort study conducted in 11 hospital emergency departments (EDs) in Canada and the United States...
April 21, 2024: Academic Emergency Medicine
#39
JOURNAL ARTICLE
Christophe A Fehlmann, Monica Taljaard, Daniel I McIssac, Laurent Suppan, Elisabeth Andereggen, Arnaud Dupuis, Frederic Rouyer, Debra Eagles, Jeffrey J Perry
AIMS: Patients undergoing emergency general surgery are at high risk of complications and death. Our objectives were to estimate the incidence of emergency general surgery in a Swiss University Hospital, to describe the characteristics and outcomes of patients undergoing such procedures, and to study the impact of age on clinical outcomes. METHODS: This was a retrospective cohort study of adult patients who visited the emergency department (ED) of Geneva University Hospitals between January 2015 and December 2019...
April 1, 2024: Swiss Medical Weekly
#40
JOURNAL ARTICLE
Theresa Coles, Kate Plyler, Alexy Hernandez, Rebecca Fillipo, Debra M Henke, Cara Arizmendi, Sandhya Lagoo-Deenadayalan, C Rory Goodwin, Thomas W LeBlanc, Erica G Horodniceanu, Vishal Bhatnagar, Bryce B Reeve, Kevin P Weinfurt
PURPOSE: Successful patient-focused drug development involves selecting and measuring outcomes in clinical trials that are important to patients. The U.S. Food & Drug Administration's definition of clinical benefit includes how patients feel, function, or survive. Patients are considered the experts in describing how they feel and function. In cancer trials, patient-reported measures of physical function provide insight into how patients function at baseline, benefit from the interventions being studied, and the impact of treatment side effects...
April 20, 2024: Quality of Life Research
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