keyword
https://read.qxmd.com/read/33134127/outcomes-of-cholera-and-measles-outbreak-alerts-in-the-democratic-republic-of-congo
#1
JOURNAL ARTICLE
J P K Makelele, S Ade, K C Takarinda, M Manzi, J Gil Cuesta, A Acma, M M Yépez, M Mashako
SETTING: In 1995, a rapid response project for humanitarian and medical emergencies, including outbreak responses, named ' Pool d'Urgence Congo ' (PUC), was implemented in the Democratic Republic of Congo by Médecins Sans Frontières. OBJECTIVE: To assess the outcomes of cholera and measles outbreak alerts that were received in the PUC surveillance system between 2016 and 2018. DESIGN: This was a retrospective cross-sectional study. RESULTS: Overall, 459 outbreak alerts were detected, respectively 69% and 31% for cholera and measles...
September 21, 2020: Public Health Action
https://read.qxmd.com/read/33119632/-we-have-already-heard-that-the-treatment-doesn-t-do-anything-so-why-should-we-take-it-a-mixed-method-perspective-on-chagas-disease-knowledge-attitudes-prevention-and-treatment-behaviour-in-the-bolivian-chaco
#2
JOURNAL ARTICLE
Sandra Parisi, Miriam Navarro, Jeremy Douglas Du Plessis, Jonathan Phillip Shock, Boris Apodaca Michel, Minerva Lucuy Espinoza, Carolina Terán, Nino Antonio Calizaya Tapia, Katharina Oltmanns, Abundio Baptista Mora, Claudia Saveedra Irala, Angel Alberto Rivera Rojas, Gonzalo Rubilar, Thomas Zoller, Michael Pritsch
BACKGROUND: Chagas disease (CD) is highly endemic in the Bolivian Chaco. The municipality of Monteagudo has been targeted by national interventions as well as by Médecins Sans Frontières to reduce infection rates, and to decentralize early diagnosis and treatment. This study seeks to determine the knowledge and attitudes of a population with increased awareness and to identify remaining factors and barriers for sustained vector control, health care seeking behaviour, and access, in order to improve future interventions...
October 2020: PLoS Neglected Tropical Diseases
https://read.qxmd.com/read/33118995/changements-dans-les-pratiques-de-d%C3%A3-pistage-de-l-antig%C3%A3-ne-prostatique-sp%C3%A3-cifique-en-ontario-entre-2003-et-2012
#3
JOURNAL ARTICLE
Louis Watson
OBJECTIFS: La présente étude analyse les changements survenus entre 2003 et 2012 dans les pratiques de dépistage de l'antigène prostatique spécifique (APS) chez les hommes âgés de 35 ans et plus en Ontario. Nous établissons des facteurs associés aux tests de l'APS, examinons si les directives de dépistage relatives à l'âge sont respectées et si les tests sont réalisés de manière opportuniste. Sont également étudiés la relation entre le revenu, le niveau d'éducation et le suivi régulier auprès d'un médecin ainsi qu'une estimation de la prévalence des tests de dépistage de l'APS en 2012...
2020: Canadian Oncology Nursing Journal
https://read.qxmd.com/read/33106850/comparative-effectiveness-of-interventions-to-improve-the-hiv-continuum-of-care-and-hiv-pre-exposure-prophylaxis-in-kenya-a-model-based-analysis
#4
JOURNAL ARTICLE
Liem B Luong Nguyen, Kenneth A Freedberg, Sitima Wanjala, David Maman, Elisabeth Szumilin, Pierre Mendiharat, Yazdan Yazdanpanah
BACKGROUND: In Western Kenya up to one quarter of the adult population was HIV-infected in 2012. The Ministry of Health, Médecins Sans Frontières (MSF) and partners implemented an HIV program that surpassed the 90-90-90 UNAIDS targets. In this generalized epidemic, we compared the effectiveness of Pre-exposure Prophylaxis (PrEP) with improving the continuum of care. METHODS: We developed a dynamic microsimulation model to project HIV incidence and infections averted to 2030...
October 27, 2020: Journal of Infectious Diseases
https://read.qxmd.com/read/33079176/one-step-forward-successful-end-of-treatment-outcomes-of-patients-with-drug-resistant-tuberculosis-who-received-concomitant-bedaquiline-and-delamanid-in-mumbai-india
#5
JOURNAL ARTICLE
Mrinalini Das, Alpa Dalal, Chinmay Laxmeshwar, Shilpa Ravi, Fatima Mamnoon, Augusto C Meneguim, Roma Paryani, Taanya Mathur, Pramila Singh, Homa Mansoor, Stobdan Kalon, Farah Naz Hossain, Nathalie Lachenal, Sylvine Coutisson, Gabriella Ferlazzo, Petros Isaakidis
BACKGROUND: The Médecins Sans Frontières Clinic in Mumbai, India, has been providing concomitant bedaquiline (BDQ) and delamanid (DLM) in treatment regimen for patients with drug-resistant tuberculosis (DR-TB) and limited therapeutic options, referred from other healthcare institutions, since 2016. The study documents the end-of-treatment outcomes, culture-conversion rates, and serious adverse events (SAEs) during treatment. METHODS: This was a retrospective cohort study based on routinely collected program data...
November 2, 2021: Clinical Infectious Diseases
https://read.qxmd.com/read/33062104/educating-the-bystander-how-contributing-to-ward-rounds-as-a-junior-doctor-or-medical-student-can-be-helpful-in-preparation-for-clinical-responsibilitiesformer-l-observateur-de-quelle-mani%C3%A3-re-la-participation-aux-tourn%C3%A3-es-des-patients-peut-elle-aider-le-r%C3%A3
#6
JOURNAL ARTICLE
https://read.qxmd.com/read/33051950/cost-effectiveness-of-screening-and-treatment-using-direct-acting-antivirals-for-chronic-hepatitis-c-virus-in-a-primary-care-setting-in-karachi-pakistan
#7
JOURNAL ARTICLE
Nyashadzaishe Mafirakureva, Aaron G Lim, Gul Ghuttai Khalid, Khawar Aslam, Linda Campbell, Hassaan Zahid, Rafael Van den Bergh, Gregoire Falq, Camille Fortas, Yves Wailly, Rosa Auat, Dmytro Donchuk, Anne Loarec, Joanna Coast, Peter Vickerman, Josephine G Walker
Despite the availability of effective direct-acting antiviral (DAA) treatments for Hepatitis C virus (HCV) infection, many people remain undiagnosed and untreated. We assessed the cost-effectiveness of a Médecins Sans Frontières (MSF) HCV screening and treatment program within a primary health clinic in Karachi, Pakistan A health state-transition Markov model was developed to estimate the cost-effectiveness of the MSF program. Program cost and outcome data were analyzed retrospectively. The incremental cost-effectiveness ratio (ICER) was calculated in terms of incremental cost (2016 US$) per disability-adjusted life year (DALY) averted from the provider's perspective over a life-time horizon...
October 14, 2020: Journal of Viral Hepatitis
https://read.qxmd.com/read/33032359/the-roadmap-for-allergology-in-europe-the-european-training-requirements-for-the-specialty-of-allergology
#8
JOURNAL ARTICLE
Roy Gerth van Wijk, Norbert Mülleneisen, Pascal Demoly, Jose Maria Olaguibel, Ted Popov, Peter Schmid-Grendelmejer, Olympia Tsilochristou
The development of the European training requirements (ETR) for medical specialties in Europe is regulated by the Union Europeénne des Médecins Spécialistes (UEMS), a non-governmental organisation representing national associations of medical specialists at European Level. The training requirements of the specialty of Allergology were developed in 1994, amended in 1997, 2001, 2002 and 2003 and published in 2004 (1) . Seventeen years after, we present an update of the ETR for the specialty of Allergology as approved by the UEMS Council held 18 October 2019 in London...
October 8, 2020: Allergy
https://read.qxmd.com/read/33021313/offering-care-for-victims-of-torture-among-a-migrant-population-in-a-transit-country-a-descriptive-study-in-a-dedicated-clinic-from-january-2017-to-june-2019
#9
JOURNAL ARTICLE
Manar Keshk, Rebecca Harrison, Walter Kizito, Christina Psarra, Phillip Owiti, Collins Timire, Mabel Morales Camacho, Gianfranco De Maio, Hadeel Safwat, Abeer Matboly, Rafael Van den Bergh
BACKGROUND: Medecins Sans Frontieres set up a clinic to provide multidisciplinary care to a vulnerable migrant population experiencing torture. We describe the population accessing care, the characteristics of care provided and patient outcomes. METHODS: A descriptive retrospective cohort study of patients enrolled in care during January 2017-June 2019 was conducted. RESULTS: Of 2512 victims of torture cases accessing the clinic, the male: female ratio was 1:1...
October 6, 2020: International Health
https://read.qxmd.com/read/32973055/qualitative-study-of-antibiotic-prescription-patterns-and-associated-drivers-in-sudan-guinea-bissau-central-african-republic-and-democratic-republic-of-congo
#10
JOURNAL ARTICLE
Tonka Eibs, Alena Koscalova, Mohit Nair, Paul Grohma, Gisa Kohler, Rawa Gafar Bakhit, Mzia Thurashvili, Estrella Lasry, Sandra Wagner Bauer, Carolina Jimenez
OBJECTIVES: The objective of this study was to address the knowledge gap regarding antibiotic use in Medecins Sans Frontiéres (MSF) projects located in Africa by exploring antibiotic prescription and consumption habits and their drivers at different healthcare levels. DESIGN: This study used an exploratory study design through thematic analysis of semistructured, in-depth interviews, focus group discussions (FGDs) and field observations in order to understand the main drivers influencing current antibiotics prescription habits and consumption habits of patients in different geographical settings...
September 24, 2020: BMJ Open
https://read.qxmd.com/read/32969602/successes-and-gaps-in-the-hiv-cascade-of-care-of-a-high-hiv-prevalence-setting-in-zimbabwe-a-population-based-survey
#11
JOURNAL ARTICLE
Nolwenn Conan, Rebecca M Coulborn, Erica Simons, Abraham Mapfumo, Tsitsi Apollo, Daniela B Garone, Esther C Casas, Adrian J Puren, Menard L Chihana, David Maman
INTRODUCTION: Gutu, a rural district in Zimbabwe, has been implementing comprehensive HIV care with the support of Médecins Sans Frontières (MSF) since 2011, decentralizing testing and treatment services to all rural healthcare facilities. We evaluated HIV prevalence, incidence and the cascade of care, in Gutu District five years after MSF began its activities. METHODS: A cross-sectional study was implemented between September and December 2016. Using multistage cluster sampling, individuals aged ≥15 years living in the selected households were eligible...
September 2020: Journal of the International AIDS Society
https://read.qxmd.com/read/32957966/preparedness-of-outpatient-health-facilities-for-ambulatory-treatment-with-all-oral-short-dr-tb-treatment-regimens-in-zhytomyr-ukraine-a-cross-sectional-study
#12
JOURNAL ARTICLE
Tinne Gils, Chinmay Laxmeshwar, Marve Duka, Khachatur Malakyan, Olga Valentinovna Siomak, Vitaly Stephanovich Didik, Natalia Lytvynenko, Yana Terleeva, Dmytri Donchuk, Petros Isaakidis
BACKGROUND: Ukraine has a high burden of drug-resistant tuberculosis (DR-TB). Mental health problems, including alcohol use disorder, are common co-morbidities. One in five DR-TB patients has human immunodeficiency virus (HIV). As part of health reform, the country is moving from inpatient care to ambulatory primary care for tuberculosis (TB). In Zhytomyr oblast, Médecins Sans Frontières (MSF) is supporting care for DR-TB patients on all-oral short DR-TB regimens. This study describes the preparedness of ambulatory care facilities in Zhytomyr oblast, Ukraine, to provide good quality ambulatory care...
September 21, 2020: BMC Health Services Research
https://read.qxmd.com/read/32956374/distribution-of-household-disinfection-kits-during-the-2014-2015-ebola-virus-outbreak-in-monrovia-liberia-the-msf-experience
#13
JOURNAL ARTICLE
Engy Ali, Guido Benedetti, Rafael Van den Bergh, Anna Halford, Luke Bawo, Moses Massaquoi, Saverio Bellizzi, Peter Maes
During the initial phase of the 2014-2016 Ebola virus disease (EVD) outbreak in Monrovia, Liberia, all hospitals' isolation capacities were overwhelmed by the sheer caseload. As a stop-gap measure to halt transmission, Medecins sans Frontieres (MSF) distributed household disinfection kits to those who were at high risk of EVD contamination. The kit contained chlorine and personal protective materials to be used for the care of a sick person or the handling of a dead body. This intervention was novel and controversial for MSF...
September 2020: PLoS Neglected Tropical Diseases
https://read.qxmd.com/read/32941533/sexual-violence-against-migrants-and-asylum-seekers-the-experience-of-the-msf-clinic-on-lesvos-island-greece
#14
JOURNAL ARTICLE
Rea A Belanteri, Sven Gudmund Hinderaker, Ewan Wilkinson, Maria Episkopou, Collins Timire, Eva De Plecker, Mzwamdile Mabhala, Kudakwashe C Takarinda, Rafael Van den Bergh
OBJECTIVES: Sexual violence can have a destructive impact on the lives of people. It is more common in unstable conditions such as during displacement or migration of people. On the Greek island of Lesvos, Médecins Sans Frontières provided medical care to survivors of sexual violence among the population of asylum seekers. This study describes the patterns of sexual violence reported by migrants and asylum seekers and the clinical care provided to them. METHODS: This is a descriptive study, using routine program data...
2020: PloS One
https://read.qxmd.com/read/32938422/person-centred-care-in-practice-perspectives-from-a-short-course-regimen-for-multi-drug-resistant-tuberculosis-in-karakalpakstan-uzbekistan
#15
JOURNAL ARTICLE
Shona Horter, Beverley Stringer, Nell Gray, Nargiza Parpieva, Khasan Safaev, Zinaida Tigay, Jatinder Singh, Jay Achar
INTRODUCTION: Person-centred care, an internationally recognised priority, describes the involvement of people in their care and treatment decisions, and the consideration of their needs and priorities within service delivery. Clarity is required regarding how it may be implemented in practice within different contexts. The standard multi-drug resistant tuberculosis (MDR-TB) treatment regimen is lengthy, toxic and insufficiently effective. 2019 World Health Organisation guidelines include a shorter (9-11-month) regimen and recommend that people with MDR-TB be involved in the choice of treatment option...
September 16, 2020: BMC Infectious Diseases
https://read.qxmd.com/read/32905304/-to-die-is-better-for-me-social-suffering-among-syrian-refugees-at-a-noncommunicable-disease-clinic-in-jordan-a-qualitative-study
#16
JOURNAL ARTICLE
Lucy Maconick, Éimhín Ansbro, Sara Ellithy, Kiran Jobanputra, Mohammad Tarawneh, Bayard Roberts
BACKGROUND: The conflict in Syria has required humanitarian agencies to implement primary-level services for non-communicable diseases (NCDs) in Jordan, given the high NCD burden amongst Syrian refugees; and to integrate mental health and psychosocial support into NCD services given their comorbidity and treatment interactions. However, no studies have explored the mental health needs of Syrian NCD patients. This paper aims to examine the interaction between physical and mental health of patients with NCDs at a Médecins Sans Frontières (MSF) clinic in Irbid, Jordan, in the context of social suffering...
2020: Conflict and Health
https://read.qxmd.com/read/32885912/predictive-molecular-pathology-in-non-small-cell-lung-cancer-in-france-the-past-the-present-and-the-perspectives
#17
REVIEW
Paul Hofman, Etienne Rouleau, Jean-Christophe Sabourin, Marc Denis, Jean-François Deleuze, Fabrice Barlesi, Pierre Laurent-Puig
The advent of molecular targets for novel therapeutics in oncology, notably for non-small cell lung carcinoma (NSCLC), led the French National Cancer Institute (INCa) to establish a national network of 28 hospital Molecular Genetics Centers for Cancer (MGCC) in 2007. In each University in France, laboratories were established to develop molecular biology testing to evaluate a few genomic alterations, initially a selection of genes, by using specific targeted polymerase chain reaction (PCR) assays. In a second phase, the number of studied genes was increased...
September 2020: Cancer Cytopathology
https://read.qxmd.com/read/32879700/oliver-wendell-holmes-1836-doctorate-dissertation-and-his-journey-in-medicine
#18
REVIEW
Stafford I Cohen
Oliver Wendell Holmes' 1836 hand written doctorate dissertation on acute pericarditis was discovered in the archives of the Boston Medical Library 101 years after it was successfully defended. It was then printed as an unabridged monograph with an explanation of its provenance. The dissertation has received little scrutiny since then. Holmes gathered materials for the scholarly work while he was a third and fourth year student at Ecole de Medecine in Paris. His mentor, Pierre-Charles-Alexandre- Louis insisted on the meticulous gathering and recording of every patient's history and findings...
August 26, 2020: World Journal of Cardiology
https://read.qxmd.com/read/32864474/eshre-clinical-embryologist-certification-the-first-10-years
#19
JOURNAL ARTICLE
Borut Kovačič, Fernando J Prados, Catherine Plas, Bryan J Woodward, Greta Verheyen, Liliana Ramos, Sirpa Mäkinen, Susanna Jamina Apter, Francesca Vidal, Søren Ziebe, M Cristina Magli, Kersti Lundin, Arne Sunde, Carlos E Plancha
STUDY QUESTION: What has the ESHRE programme 'ESHRE Certification for Clinical Embryologists' achieved after 10 years? SUMMARY ANSWER: The post-exam analysis showed a pass rate of 60% for Clinical and 50% for Senior Clinical Embryologists and a high level of internal consistency of all exams, leading to a total of 773 certified Clinical and 493 Senior Clinical Embryologists over the decade. WHAT IS KNOWN ALREADY: In an ESHRE survey on the educational and professional status of Clinical Embryology in Europe, it was found that education of laboratory personnel working in the field of assisted reproduction is highly variable between countries...
2020: Human Reproduction Open
https://read.qxmd.com/read/32843062/residents-working-with-m%C3%A3-decins-sans-fronti%C3%A3-res-training-and-pilot-evaluation
#20
JOURNAL ARTICLE
Alba Ripoll-Gallardo, Luca Ragazzoni, Ettore Mazzanti, Grazia Meneghetti, Jeffrey Michael Franc, Alessandro Costa, Francesco Della Corte
BACKGROUND: Well-prepared humanitarian workers are now more necessary than ever. Essential to the preparation process are: clearly defined learning objectives, curricula tailored to the nuances of humanitarian settings, simulation-based training, and evaluation. This manuscript describes a training program designed to prepare medical residents for their first field deployment with Médecins Sans Frontières and presents the results of a pilot assessment of its effectiveness. METHODS: The training was jointly developed by the Research Center in Emergency and Disaster Medicine- CRIMEDIM of the Università del Piemonte Orientale, Novara, Italy, and the humanitarian aid organization Médecins Sans Frontières- Italy (MSF-Italy); the following topics were covered: disaster medicine, public health, safety and security, infectious diseases, psychological support, communication, humanitarian law, leadership, and job-specific skills...
August 25, 2020: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
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