Chun-Rong Tong, Hui Wang, Yue-Hui Lin, Jun-Fang Yang, Jie Zhao, Xian Zhang, Yu-Ming Yin, Xin-Hong Fei, Ping Wu, Tong Wang, Hong-Xing Liu, Peng Cai, Zhi-Jie Wei, Juan Xiao, De-Yan Liu, Min Xiong, Jing Zhong, Dao-Pei Lu
OBJECTIVE: To analyze the clinical and laboratory features of 9 cases of gammadeltaT cell lymphoma or leukemia. METHODS: From 2007 to 2011, 9 patients with gammadeltaT-cell lymphoma/leukemia were diagnosed in our hospital. The immunophenotype of the abnormal cells were detected by flow cytometry, clonal gene rearrangement of IgH, TCRgamma, TCRdelta by PCR, chromosome karyotype analysis by G banding, acute leukemia gene and the DNA of type 1 - 8 human herpes virus by multiple nested PCR, The gammadeltaT cells were determined by T cell with TCR gammadelta chain, the malignant gammadelta T cells by the abnormal expression of T cell antigens and the precursor malignant gammadelta T cells by the expression of CD34, TDT, CD99, CD1 a or acute leukemia genes...
July 2011: Zhonghua Xue Ye Xue za Zhi, Zhonghua Xueyexue Zazhi