Myung Chul Yoo, Wan Hee Yoo, Seung Baek Kang, Yong-Wook Park, Sung Soo Kim, Kyoung Ho Moon, Yeong Wook Song, Byung Woo Min, Yoon Je Cho, Seong-Hwan Moon, Seong-Il Bin, Han-Joo Baek, Seung Cheol Shim, Sung Won Lee, Dae Hyun Yoo, Anish Mehta, Aleksandar Skuban, Diane M Cukrow, Kristel Vandormael, Li Yan
OBJECTIVE: We evaluated the COX-2 inhibitors, etoricoxib and celecoxib, in Korean patients with osteoarthritis (OA). METHODS: This study included patients (≥ 40 years of age) with a clinical and radiographic diagnosis of knee OA. Patients were randomized to etoricoxib 30 mg (qd) or celecoxib 200 mg (qd) in a 12 week randomized, controlled, double-blind study. Prior NSAID users were to demonstrate a worsening of symptoms upon withdrawal of medication. Efficacy endpoints included the time-weighted average change from baseline in the WOMAC VA 3...
December 2014: Current Medical Research and Opinion