Harimalala Ranaivo, Zhengxiao Zhang, Maud Alligier, Laurie Van Den Berghe, Monique Sothier, Stéphanie Lambert-Porcheron, Nathalie Feugier, Charlotte Cuerq, Christelle Machon, Audrey M Neyrinck, Benjamin Seethaler, Julie Rodriguez, Martin Roumain, Giulio G Muccioli, Véronique Maquet, Martine Laville, Stephan C Bischoff, Jens Walter, Nathalie M Delzenne, Julie-Anne Nazare
Chitin-glucan (CG), an insoluble dietary fiber, has been shown to improve cardiometabolic disorders associated with obesity in mice. Its effects in healthy subjects has recently been studied, revealing its interaction with the gut microbiota. In this double-blind, randomized, cross-over, twice 3-week exploratory study, we investigated the impacts of CG on the cardiometabolic profile and gut microbiota composition and functions in 15 subjects at cardiometabolic risk. They consumed as a supplement 4.5 g of CG daily or maltodextrin as control...
May 25, 2022: Scientific Reports