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JOURNAL ARTICLE
Roxane D Staiger, Tarun Mehra, Sarah R Haile, Anja Domenghino, Christoph Kümmerli, Fariba Abbassi, Damian Kozbur, Philipp Dutkowski, Milo A Puhan, Pierre-Alain Clavien
BACKGROUND: Machine learning (ML) has been successfully implemented for classification tasks (e.g., cancer diagnosis). ML performance for more challenging predictions is largely unexplored. This study's objective was to compare machine learning vs. expert-informed predictions for surgical outcome in patients undergoing major liver surgery. METHODS: Single tertiary center data on preoperative parameters and postoperative complications for elective hepatic surgery patients were included (2008-2021)...
February 13, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#22
JOURNAL ARTICLE
Babette I Kuiper, Mohammad Abu Hilal, Luca A Aldrighetti, Bergthor Björnsson, Mathieu D'Hondt, Cristina Dopazo, Åsmund A Fretland, Helena Isoniemi, J Philip Jonas, Geert Kazemier, Mickael Lesurtel, John Primrose, Andreas A Schnitzbauer, Tineke Buffart, Birgit Gruenberger, Rutger-Jan Swijnenburg, Thomas Gruenberger
BACKGROUND: There is a lack of consensus on the definition of upfront resectability and use of perioperative systemic therapy for colorectal liver metastases (CRLM). This survey aimed to summarize the current treatment strategies for upfront resectable CRLM throughout Europe. METHODS: A survey was sent to all members of the European-African Hepato-Pancreato-Biliary Association to gain insight into the current views on resectability and the use of systemic therapy for upfront resectable CRLM...
January 29, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#23
JOURNAL ARTICLE
Gregory Hooks, Han Lu, Anne Eaton, Guru Trikudanathan, Elissa Downs, Martin L Freeman, Sarah J Schwarzenberg, Timothy L Pruett, Srinath Chinnakotla, Karthik Ramanathan, Gregory J Beilman, Melena D Bellin
BACKGROUND: Total pancreatectomy with islet autotransplant (TPIAT) can improve quality of life for individuals with pancreatitis but creates health risks including diabetes, exocrine insufficiency, altered intestinal anatomy and function, and asplenia. METHODS: We studied survival and causes of death for 693 patients who underwent TPIAT between 2001 and 2020, using the National Death Index with medical records to ascertain survival after TPIAT, causes of mortality, and risk factors for death...
February 9, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#24
REVIEW
Victor Lopez-Lopez, Ester Gongora, Kohei Miura, Christoph Kuemmerli, Sergio Hernández-Kakauridze, Dilmurodjon Eshmuminov, Dominique Birrer, Victoria García-Zafra, Asuncion López-Conesa, Roberto Brusadin, Álvaro Navarro, Maria Monteagudo, Ricardo Robles-Campos
BACKGROUND: Postoperative complications after perihilar cholangiocarcinoma surgical procedure are still very high. The implementation of a multimodal prehabilitation program could improve these outcomes. Based on our experience and that of the literature in hepatobiliary and pancreatic surgery, we propose a protocol to promote its implementation. METHODS: First, we performed a retrospective analysis of the implementation feasibility of a multimodal prehabilitation program in patients' candidates for elective perihilar cholangiocarcinoma surgery in our center...
February 14, 2024: Langenbeck's Archives of Surgery
#25
JOURNAL ARTICLE
Elena Panettieri, Eduardo A Vega, Oscar Salirrosas, Satoshi Ogiso, David Geller, Claudius Conrad
BACKGROUND: Three-dimensional (3-D) liver modeling is used globally; however, its actual practice is limited to a few centers. This study aimed to assess practice patterns and barriers to the use of 3-D modeling among liver surgeons worldwide. METHODS: A survey approved by the International Hepato-Pancreato-Biliary Association research council consisting of 27 questions was conducted using an online questionnaire. Incomplete responses were excluded. RESULTS: Of 235 respondents from 46 countries, 81...
January 2024: Journal of Gastrointestinal Surgery
#26
JOURNAL ARTICLE
Reshma Ambulkar, Satya Kumar Moharana, Sohan Lal Solanki, Bindiya G Salunke, Vandana Agarwal
BACKGROUND: Patients undergoing major gastrointestinal (GI) surgery including hepato-pancreato-biliary (HPB) surgeries have large incisions, which cause severe acute postoperative pain that, if untreated, is associated with a higher incidence of postoperative morbidity and delayed recovery. METHODOLOGY: Our study included all patients who underwent elective major upper GI and HPB surgeries from 1 January 2018 to 31 December 2018. The patients were divided into two groups: the epidural and the non-epidural group...
February 12, 2024: Journal of Perioperative Practice
#27
JOURNAL ARTICLE
Giampaolo Perri, Ajith K Siriwardena, Stefan Gilg, Ernesto Sparrelid
BACKGROUND: There are no established training pathways for hepato-pancreato-biliary (HPB) surgery in Europe. This study aims to overview the current status of fellowship training from both fellows' and institutions' perspectives. METHODS: A web-based snapshot survey was distributed to all members of the European-African Hepato-Pancreato-Biliary Association (E-AHPBA) to reach for former fellows and program directors of European HPB surgery fellowships held between 2013 and 2023...
February 1, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#28
JOURNAL ARTICLE
Okello Michael, Dave Darshit, Kiconco Mary, Umar Mutekoba, Mugabi Timothy, Baseka Xavier Francis, Kakaire Denis, Kyomugisha Edward, Okuku Fred Machyo, Ddungu Henry, Buwembo William, Ocama Ponsiano
INTRODUCTION: Uganda has until recently mostly referred patients for complex hepato-pancreato-biliary (HPB) surgery abroad due to lack of local expertize. We report indications and a spectrum of surgeries performed in the first 4 years following the establishment of a routine HPB service at Lubaga Hospital (LH), Kampala, Uganda. We also detailed the challenges encountered in setting up this service. METHODS: Demographic, clinical parameters, surgery indications, procedures performed, and outcomes of consecutive patients that underwent HPB surgeries at LH from December 2018 to October 2022 were analyzed...
February 7, 2024: World Journal of Surgery
#29
JOURNAL ARTICLE
(no author information available yet)
Yttrium-90 microsphere selective internal radiation therapy (90 Y-SIRT) has been used clinically for more than 50 years for liver malignancies, with confirmed safety and efficacy. Although it has been widely used for more than 20 years abroad, 90 Y-SIRT is just getting started in China. The procedure of 90 Y-SIRT is relatively complex, which need multidisciplinary teamwork and higher requirements for operators. Once the ectopic distribution of 90 Y microspheres occurs, it may lead to relatively serious complications...
February 20, 2024: Zhonghua Yi Xue za Zhi [Chinese medical journal]
#30
JOURNAL ARTICLE
Núria Lluís, Shunsuke Onoe, Mario Serradilla-Martín, Mar Achalandabaso, Takashi Mizuno, François Jehaes, Bobby V M Dasari, Sara Mambrilla-Herrero, Ernesto Sparrelid, Anita Balakrishnan, Frederik J H Hoogwater, María J Amaral, Bodil Andersson, Frederik Berrevoet, Alexandre Doussot, Víctor López-López, Olivier Detry, Carlos Domingo-Del Pozo, Nikolaos Machairas, Damján Pekli, Cándido F Alcázar-López, Horacio Asbun, Bergthor Björnsson, Thalis Christophides, Alberto Díez-Caballero, David Francart, Colin B Noel, Donzília Sousa-Silva, Enrique Toledo-Martínez, George N Tzimas, Sheraz Yaqub, Junpei Yamaguchi, Safi Dokmak, Mikel Prieto-Calvo, Melroy A D'Souza, Harry V M Spiers, Marius C van den Heuvel, Ramón Charco, Mickaël Lesurtel, Tomoki Ebata, José M Ramia
BACKGROUND: Intraductal papillary neoplasm of the bile ducts (IPNB) is a rare disease in Western countries. The aim of this study was to compare tumor characteristics, management strategies, and outcomes between Western and Eastern patients who underwent surgical resection for IPNB. METHODS: A multi-institutional retrospective series of patients with IPNB undergoing surgery between January 2010 and December 2020 was gathered under the auspices of the European-African Hepato-Pancreato-Biliary Association (E-AHPBA), and at Nagoya University Hospital, Japan...
January 19, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#31
JOURNAL ARTICLE
Anouk G Overdevest, Jeska A Fritzsche, Mark A D Smit, Marc G Besselink, Alessandro M Bonomi, Olivier R Busch, Freek Daams, Otto M van Delden, Geert Kazemier, Jesse Langver, Cyriel Y Ponsioen, Rutger-Jan Swijnenburg, Roy L J van Wanrooij, Mattheus C B Wielenga, Babs M Zonderhuis, IJsbrand A J Zijlstra, Joris I Erdmann, Rogier P Voermans
BACKGROUND: Cholangitis is a well-known complication after hepaticojejunostomy (HJ), which is mainly caused by a stenotic anastomosis. However, the rate of cholangitis in patients with a non-stenotic (i.e. patent) HJ is unknown. We aimed to evaluate the incidence and risk factors of recurrent cholangitis in patients with a non-stenotic HJ. METHODS: This single-center retrospective cohort study included all consecutive patients who had undergone hepatobiliary or pancreatic (HPB) surgery requiring HJ (2015-2022)...
January 7, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#32
Bahaa I Aburayya, Layan R Obeidat, Farah I Kitana, Omar Al Khatib, Saleh Romman, Osama H Hamed
INTRODUCTION AND IMPORTANCE: Situs Inversus Totalis (SIT) is a rare condition characterized by the transposition of internal organs. Given the anatomical variations in SIT, surgeons must exercise extreme caution when performing laparoscopic cholecystectomy to avoid iatrogenic bile duct injury. Despite the high difficulty index associated with laparoscopic cholecystectomy in SIT, there is only one case report of common bile duct (CBD) injury in the English-language literature. CASE PRESENTATION: A 41-year-old female patient, known to have Kartagener syndrome, underwent laparoscopic cholecystectomy for acute cholecystitis and was discharged home on post-operative day one...
February 2024: International Journal of Surgery Case Reports
#33
JOURNAL ARTICLE
Tareq Al Saoudi, Kanika Chawla, Farah Khasawneh, Cristina Pollard, John Isherwood, Neil Bhardwaj, Giuseppe Garcea, Ashley Dennison
Introduction The newly qualified junior doctors in the United Kingdom face challenges due to their limited experience and unfamiliarity with their rotations. We aim to share the experience of establishing a hepato-pancreato-biliary (HPB) surgery-specific induction program at the University Hospitals of Leicester NHS Trust and assess its impact on doctors' knowledge and experience. Methods A booklet was distributed to new junior doctors, and a two-hour structured teaching session was also conducted, with pre- and post-session assessments using multiple-choice questions and a feedback survey...
December 2023: Curēus
#34
Francisco Girão de Caires, António Girão de Caires, Priscila Rietsch Flores, Duarte Gil Alves, Rita Camarneiro
Left-sided gallbladders are rare anatomical variations and a result of an abnormal embryological process. The most frequent cause for a sinistroposition gallbladder is the presence of situs inversus . We present a case of a 51-year-old male referred to the General Surgery consult due to cholelithiasis with a history of occasional post-prandial abdominal pain in the left hypochondrium and nausea associated with the ingestion of lipid-rich meals. The ultrasound revealed a gallbladder filled with calculous but without inflammatory signs or bile duct dilation, in the sinistroposition...
December 2023: Curēus
#35
JOURNAL ARTICLE
G Fiorentini, A Zironda, A Fogliati, S Warner, S Cleary, R Smoot, M Truty, M Kendrick, D Nagorney, C Thiels, P Starlinger
BACKGROUND: Gastro-jejunostomy (GJ) after pylorus-resecting pancreatoduodenectomy (PD) is most commonly performed in a hand-sewn fashion. Intestinal stapled anastomosis are reported to be as effective as hand-sewn in terms of patency and risk of leakage in other indications. However, the use of a stapled gastro-jejunostomy hasn't been fully assessed in PD. The aim of the present technical report is to evaluate functional outcomes of stapled GJ during PD, its associated effect on operative time and related complications...
December 13, 2023: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#36
JOURNAL ARTICLE
Britte H E A Ten Haaft, Alicia Furumaya, Lynn E Nooijen, Geert Kazemier, Dirk T Ubbink, Joris I Erdmann
BACKGROUND: Shared decision-making (SDM) may improve patient autonomy and health outcomes. This study assessed the level of SDM at both ends of the spectrum of hepatobiliary surgery to identify needs and opportunities for improvement. METHODS: A mixed-methods study was performed. Consultations regarding surgery for perihilar cholangiocarcinoma (pCCA) or hepatocellular adenoma (HCA) were prospectively included between September 2020 and December 2022. The level of patient involvement in treatment decision-making was assessed objectively by analysis of audio-recorded consultations using the OPTION-5 instrument...
December 20, 2023: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#37
JOURNAL ARTICLE
Ahmer Irfan, Wendy Feng, Katherine McElroy, Vikas Dudeja, Sushanth Reddy, John Bart Rose
BACKGROUND: The surgical decision making for pancreatic adenocarcinoma is complex. Although practice guidelines exist for many scenarios, these do not cover many common eventualities that may be encountered during these cases. We sought to identify the practice pattern variations amongst pancreatic surgeons in response to commonly experienced clinical scenarios. METHODS: A multiple-choice questionnaire was distributed to all full members of the IHPBA. Participant demographics, training history, and clinical practice information were obtained...
December 13, 2023: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
#38
REVIEW
Cami N Christopher, Dong-Woo Kang, Rebekah L Wilson, Paola Gonzalo-Encabo, Salvatore Ficarra, Diane Heislein, Christina M Dieli-Conwright
Gastrointestinal (GI) cancers constitute over 25% of global cancer cases annually, with hepato-pancreato-biliary (HPB) cancers presenting particularly poor prognosis and challenging surgical treatments. While advancements in clinical care have improved post-operative outcomes over time, surgery for HPB cancers remains associated with high morbidity and mortality rates. Patients with HPB cancer are often older, diagnosed at later stages, and have a higher prevalence of co-morbid conditions, leading to reduced life expectancy, suboptimal post-operative recovery, and increased recurrence risk...
December 8, 2023: Nutrients
#39
JOURNAL ARTICLE
Mihir Rao, Bishow Karki, Julie Jeffery, Abdul Hakeem
A woman in her 60s was referred to the hepato-pancreato-biliary clinic for further assessment of a large hepatic cyst, which was incidentally identified by echocardiography. She was being investigated for possible crescendo angina on the backdrop of a 6-month history of increasing chest pain, shortness of breath, sweating, orthopnoea and paroxysmal nocturnal dyspnoea. Coronary angiography and echocardiography demonstrated normal cardiac physiology. A CT abdomen/pelvis confirmed an 8.5 cm hepatic cyst indenting the posterior and caudate lobes and abutting the inferior vena cava...
December 21, 2023: BMJ Case Reports
#40
JOURNAL ARTICLE
Deniece Riviere, Erik Aarntzen, Erwin van Geenen, David Chang, Lioe-Fee de Geus-Oei, Lodewijk Brosens, Kees van Laarhoven, Martin Gotthardt, John Hermans
BACKGROUND: Retrospective analysis to investigate the relationship between the flow-metabolic phenotype and overall survival (OS) of pancreatic ductal adenocarcinoma (PDAC) and its potential clinical utility. METHODS: Patients with histopathologically proven PDAC between 2005 and 2014 using tumor attenuation on routine pre-operative CECT as a surrogate for the vascularity and [18 F]FDG-uptake as a surrogate for metabolic activity on [18 F]FDG-PET. RESULTS: In total, 93 patients (50 male, 43 female, median age 63) were included...
November 25, 2023: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
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