Lei Yu, Ming Yi, Jiayu Guo, Jinbiao Li, Huixing Zeng, Liqian Cui, Xiangming Xu, Gang Liu, Yuhua Fan, Jinsheng Zeng, Shihui Xing, Yicong Chen, Meng Wang, Shuangquan Tan, Leow Yi Jin, Dilip Kumar, Ashwati Vipin, Soo See Ann, Fatin Zahra Binte Zailan, Gurveen Kaur Sandhu, Nagaendran Kandiah, Chao Dang
Cerebral small vessel disease (SVD) may be associated with an increased risk of depressive symptoms. Serum uric acid (SUA), an antioxidant, may be involved in the occurrence and development of depressive symptoms, but the mechanism remains unknown. Moreover, the relationship between structural brain networks and SUA has not been explored. This study examined the relationship between SUA and depressive symptoms in patients with SVD using graph theory analysis. We recruited 208 SVD inpatients and collected fasting blood samples upon admission...
March 30, 2024: Heliyon