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EDITORIAL
Anke H C Gielen
No abstract text is available yet for this article.
September 14, 2024: United European Gastroenterology Journal
#2
JOURNAL ARTICLE
Iulia Florentina Tincu, Luiza Elena Bordei, Lucica Luminita Gales, Larisa Alexandra Duchi, Loredana Dobrescu, Bianca Teodora Chenescu
Background/objectives: An increase in the incidence of eosinophilic esophagitis (EoE) in children has been reported worldwide in the last decade. We conducted a study in a tertiary pediatric gastroenterology unit aimed at analyzing the clinical manifestations, biochemical markers, and endoscopic features of children with EoE in comparison to patients with non-eosinophilic esophagitis. Methods : This is a prospective analysis involving children with symptoms related to esophageal dysfunction, who had esophagogastroduodenoscopies with esophageal biopsies between January 2021 and April 2024 at "Dr...
August 25, 2024: Journal of Clinical Medicine
#3
REVIEW
Yi-Jin Yu, Damian Kołat, Żaneta Kałuzińska-Kołat, Zhu Liang, Bo-Qiang Peng, Yun-Feng Zhu, Kai Liu, Jia-Xin Mei, Gang Yu, Wei-Han Zhang, Xiao-Long Chen, Kun Yang, Jian-Kun Hu, Lin-Yong Zhao
Activating enhancer-binding protein 2 (AP-2) is a family of transcription factors (TFs) that play crucial roles in regulating embryonic and oncogenic development. In addition to splice isoforms, five major family members encoded by the TFAP2A/B/C/D/E genes have been identified in humans, i.e., AP-2α/β/γ/δ/ε. In general, the first three TFs have been studied more thoroughly than AP-2δ or AP-2ε. Currently, there is a relatively limited body of literature focusing on the AP-2 family in the context of gastroenterological research, and a comprehensive overview of the existing knowledge and recommendations for further research directions is lacking...
August 23, 2024: International Journal of Molecular Sciences
#4
JOURNAL ARTICLE
Hanlei Yang, Yulan Wang, Yuewei Zhao, Leiqun Cao, Changqiang Chen, Wenjun Yu
BACKGROUND: Esophageal diseases (ED) are a kind of common diseases of upper digestive tract. Previous studies have proved that metabolic disorders are closely related to the occurrence and development of ED. However, there is a lack of evidence for causal relationships between metabolites and ED, as well as between metabolite ratios representing enzyme activities and ED. Herein, we explored the causality of genetically determined metabolites (GDMs) on ED through Mendelian Randomization (MR) study...
September 14, 2024: BMC Gastroenterology
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JOURNAL ARTICLE
Ingo Steinbrück, Viktor Rempel, Armin Kuellmer, Valentin Miedtke, Siegbert Faiss, Thomas von Hahn, Jürgen Pohl, Johannes Grothaus, Matthias Friesicke, Arthur Schmidt, Hans-Peter Allgaier
BACKGROUND: The European Society of Gastroenterology and Endoscopy recommends a primarily flexible endoscopic approach for the treatment of Zenker's diverticulum. Due to the rarity of the disorder, evidence for its effectiveness and safety comes mainly from small, retrospective, single-center studies. METHODS: In this retrospective, observational, multicenter cohort study, data from six German tertiary referral centers were analyzed. The primary outcome parameters were technical and clinical success; among the secondary outcomes, the rates of adverse events (AE) and re-admission with symptomatic recurrence and mortality were the most relevant...
September 13, 2024: Surgical Endoscopy
#6
JOURNAL ARTICLE
Unique Tyagi, Sridhar Sundaram, Aadish Kumar Jain, Kiran Mane
No abstract text is available yet for this article.
September 11, 2024: Gastrointestinal Endoscopy
#7
JOURNAL ARTICLE
Yirui Zhang, Wenjin Xiao, Duanmin Hu
No abstract text is available yet for this article.
September 11, 2024: Gastrointestinal Endoscopy
#8
JOURNAL ARTICLE
Jianhua Rao, Zeng Wang, Fei Yu, Junda Li, Wenzhu Li, Zhengfeng Xuan, Yongquan Chi, Feng Zhang, Liming Tang, Feng Cheng
BACKGROUND & AIMS: XBP1, most conserved transcription factor of endoplasmic reticulum (ER) stress, plays important roles in physiological and pathological settings and has profound effects on disease progression and prognosis, so it's necessary to investigate XBP1 in macrophage-originated sterile inflammation during liver ischemia/reperfusion injury (IRI). Macrophage XBP1 expression and liver injury are analyzed in patients undergoing ischemia-related hepatectomy. METHODS: A myeloid-specific male XBP1-knockout (XBP1M-KO ) strain is created for function and mechanism of XBP1 on macrophage-derived sterile inflammation in murine liver IRI with in-vitro parallel research...
September 11, 2024: Cellular and Molecular Gastroenterology and Hepatology
#9
REVIEW
Mahrez Fissah, Adel Rechach, Meriem Charifi, Farouk Menzou, Said Taharboucht, Messaouda Djouhri, Leila Talbi, Nadia Touati, Lamine Atif, Mehdi Rabhia, Ahcene Chibane
INTRODUCTION: Recent studies have demonstrated the growing interest in cardiovascular risk in Crohn's disease (CD), the aim of our work is to highlight the need for research into the frequency of arterial stiffness (AS) and its link with certain associated factors, particularly those related to inflammation. MATERIALS AND METHODS: This was a cross-sectional observational study involving 118 patients with CD. Pulse wave velocity (PWV) measured by applanation tonometry was the criterion for calculating AS, the study also investigated the association of AS especially the indicators of inflammation, as well as the impact of anti TNF alpha therapy on AS...
September 11, 2024: Gastroenterología y Hepatología
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JOURNAL ARTICLE
A Mínguez, E Coello, A Garrido, P Ripoll, M Gomez, M Aguas, M Iborra, E Cerrillo, L Tortosa, V Bayarri, N Bueno, M J Fernández, R Marqués, P Nos, G Bastida
BACKGROUND AND AIMS: Ustekinumab is an effective treatment for inflammatory bowel diseases. However, some patients do not respond to conventional doses. The aim of the study was to evaluate the effectiveness of intravenous maintenance Ustekinumab in patients with secondary failure. METHODS: Single-center, retrospective study in adult patients with intravenous maintenance ustekinumab. The reduction of biochemical activity markers, ustekinumab trough levels and clinical indices of activity were evaluated...
September 11, 2024: Gastroenterología y Hepatología
#11
JOURNAL ARTICLE
Francisco Vara-Luiz, Helena Pires, Ivo Mendes, Carolina Palma, Eduardo Fernandes, Ana Elisa Teles, Francisco Martins do Vale, Marta Patita, Jorge Fonseca, Pedro Pinto-Marques
No abstract text is available yet for this article.
September 11, 2024: Gastroenterología y Hepatología
#12
REVIEW
Anne F Peery, Hamed Khalili, Andreas Münch, Darrell S Pardi
Microscopic colitis is an inflammatory bowel disease that commonly presents with debilitating chronic watery diarrhea. Recent epidemiologic studies and randomized trials of therapeutics have improved our understanding of the disease. Medications such as non-steroidal anti-inflammatories, proton pump inhibitors, and antidepressants have traditionally been considered as the main risk factors for microscopic colitis. However, recent studies have challenged this observation. Additionally, a number of epidemiologic studies have identified other risk factors for the disease including older age, female sex, smoking, alcohol use, immune-mediated diseases, and select gastrointestinal infections...
September 11, 2024: Clinical Gastroenterology and Hepatology
#13
JOURNAL ARTICLE
Xu-Fen Zeng, Krista A Varady, Xiang-Dong Wang, Giovanni Targher, Christopher D Byrne, Reema Tayyem, Giovanni Latella, Ina Bergheim, Rodrigo Valenzuela, Jacob George, Carolyn Newberry, Ju-Sheng Zheng, Elena S George, C Wendy Spearman, Meropi D Kontogianni, Danijela Ristic-Medic, Wilza Arantes Ferreira Peres, Gamze Yurtdaş Depboylu, Wanshui Yang, Xu Chen, Fredrik Rosqvist, Christos S Mantzoros, Luca Valenti, Hannele Yki-Järvinen, Antonella Mosca, Silvia Sookoian, Anoop Misra, Yusuf Yilmaz, Won Kim, Yasser Fouad, Giada Sebastiani, Vincent Wai-Sun Wong, Fredrik Åberg, Yu Jun Wong, Pianhong Zhang, Francisco-Javier Bermúdez-Silva, Yan Ni, Monica Lupsor-Platon, Wah Kheong Chan, Nahum Méndez-Sánchez, Robert J de Knegt, Shahinul Alam, Sombat Treeprasertsuk, Li Wang, Mulong Du, Tiejun Zhang, Ming-Lung Yu, Huijie Zhang, Xingshun Qi, Xin Liu, Kanokwan Pinyopornpanish, Yu-Chen Fan, Niu Kaijun, Josep C Jimenez-Chillaron, Ming-Hua Zheng
Metabolic dysfunction-associated fatty liver disease (MAFLD) or metabolic dysfunction-associated steatotic liver disease (MASLD), has become the leading cause of chronic liver disease worldwide. Optimal dietary intervention strategies for MAFLD are not standardized. This study aimed to achieve consensus on prevention of MAFLD through dietary modification. A multidisciplinary panel of 55 international experts, including specialists in hepatology, gastroenterology, dietetics, endocrinology and other medical specialties from six continents collaborated in a Delphi-based consensus development process...
September 11, 2024: Metabolism: Clinical and Experimental
#14
JOURNAL ARTICLE
Hanna Blaney, Luis Antonio Díaz, Nhi Li, Gurpreet Malhi, Rokhsana Mortuza, Xiaolong Qi, Anand V Kulkarni, Ramon Bataller, Joaquin Cabezas, Alexandre Louvet, Elliot B Tapper, Juan Pablo Arab
No abstract text is available yet for this article.
September 10, 2024: Lancet. Gastroenterology & Hepatology
#15
JOURNAL ARTICLE
Parth Patel, Manav Patel, Mohamad Ayman Ebrahim, Priyadarshini Loganathan, Douglas G Adler
BACKGROUND: Anastomotic strictures following colectomy and proctectomy are a significant cause of benign lower gastrointestinal tract (LGIT) obstruction, with a reported incidence of up to 30%. Endoscopic interventions such as balloon dilation, stricturotomy, mechanical dilation, electrocautery incision, and stent placement are utilized for management. This meta-analysis aimed to evaluate the efficacy and safety of endoscopic interventions for the management of benign LGIT anastomotic strictures...
September 13, 2024: Digestive Diseases and Sciences
#16
JOURNAL ARTICLE
Amit Patel, Loren Laine, Paul Moayyedi, Justin Wu
DESCRIPTION: The purpose of this American Gastroenterological Association (AGA) Institute Clinical Practice Update (CPU) is to summarize the available evidence and offer expert Best Practice Advice on the integration of potassium-competitive acid blockers (P-CABs) in the clinical management of foregut disorders, specifically including gastroesophageal reflux disease, Helicobacter pylori infection, and peptic ulcer disease. METHODS: This expert review was commissioned and approved by the AGA Institute Governing Board and CPU Committee to provide timely guidance on a topic of high clinical importance to the AGA membership...
September 11, 2024: Gastroenterology
#17
JOURNAL ARTICLE
Jorge D Machicado, Sunil G Sheth, Jean M Chalhoub, Nauzer Forbes, Madhav Desai, Saowanee Ngamruengphong, Georgios I Papachristou, Vaibhav Sahai, Ibrahim Nassour, Wasif Abidi, Omeed Alipour, Stuart K Amateau, Nayantara Coelho-Prabhu, Natalie Cosgrove, Sherif E Elhanafi, Larissa L Fujii-Lau, Divyanshoo R Kohli, Neil B Marya, Swati Pawa, Wenly Ruan, Nikhil R Thiruvengadam, Nirav C Thosani, Bashar J Qumseya
No abstract text is available yet for this article.
September 10, 2024: Gastrointestinal Endoscopy
#18
JOURNAL ARTICLE
Amit Bhatt, Juan Carlos Bucobo, Maaza Abdi, Venkata S Akshintala, Dennis Chen, Yen-I Chen, Andrew P Copland, Koushik K Das, David J Desilets, Mohit Girotra, Samuel Han, Allon Kahn, Kumar Krishnan, Galen Leung, David R Lichtenstein, Girish Mishra, V Raman Muthusamy, Jorge V Obando, Frances U Onyimba, Swati Pawa, Tarun Rustagi, Sonali S Sakaria, Monica Saumoy, Nikrad Shahnavaz, Guru Trikudanathan, Arvind J Trindade, Daniela Guerrero Vinsard, Julie Yang, Ryan Law
BACKGROUND AND AIMS: EMR and endoscopic submucosal dissection (ESD) are minimally invasive endoscopic techniques, developed for the removal of benign and early malignant lesions throughout the GI tract. Submucosal injection of a marking agent can help to identify lesions during surgery. Endoscopic resection frequently involves "lifting" of the lesions by injection of a substance within the submucosal space to create a cushion for safe resection. This review summarizes the current techniques and agents available for endoscopic marking and lifting of GI tract lesions...
September 10, 2024: Gastrointestinal Endoscopy
#19
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
January 2024: Journal of Gastroenterology and Hepatology
#20
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
January 2024: Journal of Gastroenterology and Hepatology
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