Leontios Pappas, Islam Baiev, Stephanie Reyes, Andrea Grace Bocobo, Apurva Jain, Kristen Spencer, Tri Minh Le, Osama E Rahma, Jordan Maurer, Jen Stanton, Karen Zhang, Anaemy Danner De Armas, Thomas T Deleon, Marc Roth, Mary Linton B Peters, Andrew X Zhu, Kylie Boyhen, Christine VanCott, Tushar Patel, Lewis R Roberts, Stacie Lindsey, Nora Horick, Jochen K Lennerz, A John Iafrate, Laura Williams Goff, Kabir Mody, Mitesh J Borad, Rachna T Shroff, Milind M Javle, R Katie Kelley, Lipika Goyal
PURPOSE: Increased awareness of the distinct tumor biology for adolescents and young adults (AYAs) with cancer has led to improvement in outcomes for this population. However, in cholangiocarcinoma (CCA), a paucity of data exist on the AYA population. To our knowledge, we present the largest study to date on AYA disease biology, treatment patterns, and survival outcomes in CCA. METHODS: A multi-institutional cohort of patients with CCA diagnosed with intrahepatic cholangiocarcinoma (ICC) or extrahepatic cholangiocarcinoma (ECC) was used for analysis...
August 2023: JCO Precision Oncology