Q Y Li, Y Liang, N N Dai, Y X Wang, B T Zhu, R Wu, H Zhu, Y C Sun
Hemophagocytic lymphohistiocytosis (HLH) was a life-threatening syndrome due to the uncontrolled immune activation of cytotoxic T lymphocytes, natural killer (NK) cells, and macrophages. HLH is characterized by primary and secondary causes, the early diagnosis and treatment of patients are closely related to the prognosis and clinical outcome of patients. The clinical presentation is variable but mostly includes prolonged fever, splenomegaly, coagulopathy, hypertriglyceridemia, and hemophagocytosis, none of them is specific and particular for HLH...
December 18, 2022: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences