keyword
https://read.qxmd.com/read/38740819/equicity-game-a-mathematical-serious-game-for-participatory-design-of-spatial-configurations
#21
JOURNAL ARTICLE
Pirouz Nourian, Shervin Azadi, Nan Bai, Bruno de Andrade, Nour Abu Zaid, Samaneh Rezvani, Ana Pereira Roders
We propose a mathematical framework for developing social-choice games that are designed to mediate decision-making processes for city planning, urban area redevelopment, and architectural configuration of urban housing complexes. The proposed framework features a digital serious gaming approach for participatory design to support transparency and inclusion in the process of decision-making and ensure an equitable balance of sustainable development goals in spatial design outcomes. The mathematical process consists of a Markovian design machine for balancing the design decisions of actors, a massing configurator equipped with fuzzy logic and multi-criteria decision analysis, algebraic graph-theoretical accessibility evaluators, and automated solar-climatic evaluators using geospatial computational geometry...
May 13, 2024: Scientific Reports
https://read.qxmd.com/read/38740666/exploring-the-potential-of-artificial-intelligence-as-a-facilitating-tool-for-formulation-development-in-fluidized-bed-processor-a-comprehensive-review
#22
REVIEW
Aachal A Gosavi, Tanaji D Nandgude, Rakesh K Mishra, Dhiraj B Puri
This in-depth study looks into how artificial intelligence (AI) could be used to make formulation development easier in fluidized bed processes (FBP). FBP is complex and involves numerous variables, making optimization challenging. Various AI techniques have addressed this challenge, including machine learning, neural networks, genetic algorithms, and fuzzy logic. By integrating AI with experimental design, process modeling, and optimization strategies, intelligent systems for FBP can be developed. The advantages of AI in this context include improved process understanding, reduced time and cost, enhanced product quality, and robust formulation optimization...
May 13, 2024: AAPS PharmSciTech
https://read.qxmd.com/read/38740530/deep-learning-features-and-metabolic-tumor-volume-based-on-pet-ct-to-construct-risk-stratification-in-non-small-cell-lung-cancer
#23
JOURNAL ARTICLE
Linjun Ju, Wenbo Li, Rui Zuo, Zheng Chen, Yue Li, Yuyue Feng, Yuting Xiang, Hua Pang
RATIONALE AND OBJECTIVES: To build a risk stratification by incorporating PET/CT-based deep learning features and whole-body metabolic tumor volume (MTVwb ), which was to make predictions about overall survival (OS) and progression-free survival (PFS) for those with non-small cell lung cancer (NSCLC) as a complement to the TNM staging. MATERIALS AND METHODS: The study enrolled 590 patients with NSCLC (413 for training and 177 for testing). Features were extracted by employing a convolutional neural network...
May 12, 2024: Academic Radiology
https://read.qxmd.com/read/38739507/cross-domain-mutual-assistance-learning-framework-for-fully-automated-diagnosis-of-primary-tumor-in-nasopharyngeal-carcinoma
#24
JOURNAL ARTICLE
Xiuyu Dong, Kaifan Yang, Jinyu Liu, Fan Tang, Wenjun Liao, Yu Zhang, Shujun Liang
Accurate T-staging of nasopharyngeal carcinoma (NPC) holds paramount importance in guiding treatment decisions and prognosticating outcomes for distinct risk groups. Regrettably, the landscape of deep learning-based techniques for T-staging in NPC remains sparse, and existing methodologies often exhibit suboptimal performance due to their neglect of crucial domain-specific knowledge pertinent to primary tumor diagnosis. To address these issues, we propose a new cross-domain mutual-assistance learning framework for fully automated diagnosis of primary tumor using H&N MR images...
May 13, 2024: IEEE Transactions on Medical Imaging
https://read.qxmd.com/read/38739445/potential-of-large-language-models-in-health-care-delphi-study
#25
JOURNAL ARTICLE
Kerstin Denecke, Richard May, Octavio Rivera Romero
BACKGROUND: A large language model (LLM) is a machine learning model inferred from text data that captures subtle patterns of language use in context. Modern LLMs are based on neural network architectures that incorporate transformer methods. They allow the model to relate words together through attention to multiple words in a text sequence. LLMs have been shown to be highly effective for a range of tasks in natural language processing (NLP), including classification and information extraction tasks and generative applications...
May 13, 2024: Journal of Medical Internet Research
https://read.qxmd.com/read/38739324/multimodal-mri-segmentation-of-key-structures-for-microvascular-decompression-via-knowledge-driven-mutual-distillation-and-topological-constraints
#26
JOURNAL ARTICLE
Renzhe Tu, Doudou Zhang, Caizi Li, Linxia Xiao, Yong Zhang, Xiaodong Cai, Weixin Si
PURPOSE: Microvascular decompression (MVD) is a widely used neurosurgical intervention for the treatment of cranial nerves compression. Segmentation of MVD-related structures, including the brainstem, nerves, arteries, and veins, is critical for preoperative planning and intraoperative decision-making. Automatically segmenting structures related to MVD is still challenging for current methods due to the limited information from a single modality and the complex topology of vessels and nerves...
May 13, 2024: International Journal of Computer Assisted Radiology and Surgery
https://read.qxmd.com/read/38738534/the-impact-of-model-assumptions-on-personalized-lung-cancer-screening-recommendations
#27
JOURNAL ARTICLE
Kevin Ten Haaf, Koen de Nijs, Giulia Simoni, Andres Alban, Pianpian Cao, Zhuolu Sun, Jean Yong, Jihyoun Jeon, Iakovos Toumazis, Summer S Han, G Scott Gazelle, Chung Ying Kong, Sylvia K Plevritis, Rafael Meza, Harry J de Koning
BACKGROUND: Recommendations regarding personalized lung cancer screening are being informed by natural-history modeling. Therefore, understanding how differences in model assumptions affect model-based personalized screening recommendations is essential. DESIGN: Five Cancer Intervention and Surveillance Modeling Network (CISNET) models were evaluated. Lung cancer incidence, mortality, and stage distributions were compared across 4 theoretical scenarios to assess model assumptions regarding 1) sojourn times, 2) stage-specific sensitivities, and 3) screening-induced lung cancer mortality reductions...
May 13, 2024: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://read.qxmd.com/read/38736487/accurate-categorization-and-rapid-pathological-diagnosis-correction-with-micro-raman-technique-in-human-lung-adenocarcinoma-infiltration-level
#28
JOURNAL ARTICLE
Bo Dai, Dong Han, Yufei Miao, Yong Zhou, Mohammadreza Hajiarbabi, Yiqing Wang, Christopher J Butch, Huiming Cai, Jian Hu
BACKGROUND: In the context of surgical interventions for lung adenocarcinoma (LADC), precise determination of the extent of LADC infiltration plays a pivotal role in shaping the surgeon's strategic approach to the procedure. The prevailing diagnostic standard involves the expeditious intraoperative pathological diagnosis of areas infiltrated by LADC. Nevertheless, current methodologies rely on the visual interpretation of tissue images by proficient pathologists, introducing an error margin of up to 15...
April 29, 2024: Translational Lung Cancer Research
https://read.qxmd.com/read/38736372/cognitive-brain-activity-before-and-after-surgery-in-meningioma-patients
#29
JOURNAL ARTICLE
Irena T Schouwenaars, Miek J de Dreu, Geert-Jan M Rutten, Nick F Ramsey, J Martijn Jansma
Neuropsychological studies have demonstrated that meningioma patients frequently exhibit cognitive deficits before surgery and show only limited improvement after surgery. Combining neuropsychological with functional imaging measurements can shed more light on the impact of surgery on cognitive brain function. We aimed to evaluate whether surgery affects cognitive brain activity in such a manner that it may mask possible changes in cognitive functioning measured by neuropsychological tests. Twenty-three meningioma patients participated in a fMRI measurement using a verbal working memory task as well as three neuropsychological tests focused on working memory, just before and 3 months after surgery...
May 13, 2024: European Journal of Neuroscience
https://read.qxmd.com/read/38735423/common-neural-dysfunction-of-economic-decision-making-across-psychiatric-conditions
#30
JOURNAL ARTICLE
Chunliang Feng, Qingxia Liu, Chuangbing Huang, Ting Li, Li Wang, Feilong Liu, Simon B Eickhoff, Chen Qu
Adaptive decision-making, which is often impaired in various psychiatric conditions, is essential for well-being. Recent evidence has indicated that decision-making capacity in multiple tasks could be accounted for by latent dimensions, enlightening the question of whether there is a common disruption of brain networks in economic decision-making across psychiatric conditions. Here, we addressed the issue by combining activation/lesion network mapping analyses with a transdiagnostic brain imaging meta-analysis...
May 10, 2024: NeuroImage
https://read.qxmd.com/read/38734835/predicting-early-mortality-and-severe-intraventricular-hemorrhage-in-very-low-birth-weight-preterm-infants-a-nationwide-multicenter-study-using-machine-learning
#31
MULTICENTER STUDY
Yun-Hsiang Yang, Ts-Ting Wang, Yi-Han Su, Wei-Ying Chu, Wei-Ting Lin, Yen-Ju Chen, Yu-Shan Chang, Yung-Chieh Lin, Chyi-Her Lin, Yuh-Jyh Lin
Our aim was to develop a machine learning-based predictor for early mortality and severe intraventricular hemorrhage (IVH) in very-low birth weight (VLBW) preterm infants in Taiwan. We collected retrospective data from VLBW infants, dividing them into two cohorts: one for model development and internal validation (Cohort 1, 2016-2021), and another for external validation (Cohort 2, 2022). Primary outcomes included early mortality, severe IVH, and early poor outcomes (a combination of both). Data preprocessing involved 23 variables, with the top four predictors identified as gestational age, birth body weight, 5-min Apgar score, and endotracheal tube ventilation...
May 12, 2024: Scientific Reports
https://read.qxmd.com/read/38734748/deep-learning-based-classification-of-anti-personnel-mines-and-sub-gram-metal-content-in-mineralized-soil-dl-mmd
#32
JOURNAL ARTICLE
Shahab Faiz Minhas, Maqsood Hussain Shah, Talal Khaliq
De-mining operations are of critical importance for humanitarian efforts and safety in conflict-affected regions. In this paper, we address the challenge of enhancing the accuracy and efficiency of mine detection systems. We present an innovative Deep Learning architecture tailored for pulse induction-based Metallic Mine Detectors (MMD), so called DL-MMD. Our methodology leverages deep neural networks to distinguish amongst nine distinct materials with an exceptional validation accuracy of 93.5%. This high level of precision enables us not only to differentiate between anti-personnel mines, without metal plates but also to detect minuscule 0...
May 11, 2024: Scientific Reports
https://read.qxmd.com/read/38734024/clinical-significance-of-combined-tumour-infiltrating-lymphocytes-and-microsatellite-instability-status-in-colorectal-cancer-a-systematic-review-and-network-meta-analysis
#33
JOURNAL ARTICLE
Durgesh Wankhede, Tanwei Yuan, Matthias Kloor, Niels Halama, Hermann Brenner, Michael Hoffmeister
BACKGROUND: Microsatellite instability (MSI) status and tumour-infiltrating lymphocytes (TIL) are established prognostic factors in colorectal cancer. Previous studies evaluating the combination of TIL and MSI status identified distinct colorectal cancer subtypes with unique prognostic associations. However, these studies were often limited by sample size, particularly for MSI-high (MSI-H) tumours, and there is no comprehensive summary of the available evidence. We aimed to review the literature to compare the survival outcomes associated with the subtypes derived from the integrated MSI-TIL classification in patients with colorectal cancer...
May 8, 2024: Lancet. Gastroenterology & Hepatology
https://read.qxmd.com/read/38733793/learning-active-subspaces-and-discovering-important-features-with-gaussian-radial-basis-functions-neural-networks
#34
JOURNAL ARTICLE
Danny D'Agostino, Ilija Ilievski, Christine Annette Shoemaker
Providing a model that achieves a strong predictive performance and is simultaneously interpretable by humans is one of the most difficult challenges in machine learning research due to the conflicting nature of these two objectives. To address this challenge, we propose a modification of the radial basis function neural network model by equipping its Gaussian kernel with a learnable precision matrix. We show that precious information is contained in the spectrum of the precision matrix that can be extracted once the training of the model is completed...
April 29, 2024: Neural Networks: the Official Journal of the International Neural Network Society
https://read.qxmd.com/read/38732925/low-cost-recognition-of-plastic-waste-using-deep-learning-and-a-multi-spectral-near-infrared-sensor
#35
JOURNAL ARTICLE
Uriel Martinez-Hernandez, Gregory West, Tareq Assaf
This work presents an approach for the recognition of plastics using a low-cost spectroscopy sensor module together with a set of machine learning methods. The sensor is a multi-spectral module capable of measuring 18 wavelengths from the visible to the near-infrared. Data processing and analysis are performed using a set of ten machine learning methods (Random Forest, Support Vector Machines, Multi-Layer Perceptron, Convolutional Neural Networks, Decision Trees, Logistic Regression, Naive Bayes, k-Nearest Neighbour, AdaBoost, Linear Discriminant Analysis)...
April 28, 2024: Sensors
https://read.qxmd.com/read/38732918/minimizing-task-age-upon-decision-for-low-latency-mec-networks-task-offloading-with-action-masked-deep-reinforcement-learning
#36
JOURNAL ARTICLE
Zhouxi Jiang, Jianfeng Yang, Xun Gao
In this paper, we consider a low-latency Mobile Edge Computing (MEC) network where multiple User Equipment (UE) wirelessly reports to a decision-making edge server. At the same time, the transmissions are operated with Finite Blocklength (FBL) codes to achieve low-latency transmission. We introduce the task of Age upon Decision (AuD) aimed at the timeliness of tasks used for decision-making, which highlights the timeliness of the information at decision-making moments. For the case in which dynamic task generation and random fading channels are considered, we provide a task AuD minimization design by jointly selecting UE and allocating blocklength...
April 28, 2024: Sensors
https://read.qxmd.com/read/38732885/a-multi-agent-rl-algorithm-for-dynamic-task-offloading-in-d2d-mec-network-with-energy-harvesting
#37
JOURNAL ARTICLE
Xin Mi, Huaiwen He, Hong Shen
Delay-sensitive task offloading in a device-to-device assisted mobile edge computing (D2D-MEC) system with energy harvesting devices is a critical challenge due to the dynamic load level at edge nodes and the variability in harvested energy. In this paper, we propose a joint dynamic task offloading and CPU frequency control scheme for delay-sensitive tasks in a D2D-MEC system, taking into account the intricacies of multi-slot tasks, characterized by diverse processing speeds and data transmission rates. Our methodology involves meticulous modeling of task arrival and service processes using queuing systems, coupled with the strategic utilization of D2D communication to alleviate edge server load and prevent network congestion effectively...
April 26, 2024: Sensors
https://read.qxmd.com/read/38732365/novel-tools-for-single-comparative-and-unified-evaluation-of-qualitative-and-quantitative-bioassays-ss-pv-roc-and-ss-j-pv-psi-index-roc-curves-with-integrated-concentration-distributions-and-ss-j-pv-psi-index-cut-off-diagrams
#38
JOURNAL ARTICLE
Peter Oehr
Background: This investigation is both a study of potential non-invasive diagnostic approaches for the bladder cancer biomarker UBC® Rapid test and a study including novel comparative methods for bioassay evaluation and comparison that uses bladder cancer as a useful example. The objective of the paper is not to investigate specific data. It is used only for demonstration, partially to compare ROC methodologies and also to show how both sensitivity/specificity and predictive values can be used in clinical diagnostics and decision making...
April 30, 2024: Diagnostics
https://read.qxmd.com/read/38732220/poor-decision-making-and-sociability-impairment-following-central-serotonin-reduction-in-inducible-tph2-knockdown-rats
#39
JOURNAL ARTICLE
Lucille Alonso, Polina Peeva, Tania Fernández-Del Valle Alquicira, Narda Erdelyi, Ángel Gil Nolskog, Michael Bader, York Winter, Natalia Alenina, Marion Rivalan
Serotonin is an essential neuromodulator for mental health and animals' socio-cognitive abilities. However, we previously found that a constitutive depletion of central serotonin did not impair rat cognitive abilities in stand-alone tests. Here, we investigated how a mild and acute decrease in brain serotonin would affect rats' cognitive abilities. Using a novel rat model of inducible serotonin depletion via the genetic knockdown of tryptophan hydroxylase 2 (TPH2), we achieved a 20% decrease in serotonin levels in the hypothalamus after three weeks of non-invasive oral doxycycline administration...
May 3, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38729150/a-latent-pool-of-neurons-silenced-by-sensory-evoked-inhibition-can-be-recruited-to-enhance-perception
#40
JOURNAL ARTICLE
Oliver M Gauld, Adam M Packer, Lloyd E Russell, Henry W P Dalgleish, Maya Iuga, Francisco Sacadura, Arnd Roth, Beverley A Clark, Michael Häusser
To investigate which activity patterns in sensory cortex are relevant for perceptual decision-making, we combined two-photon calcium imaging and targeted two-photon optogenetics to interrogate barrel cortex activity during perceptual discrimination. We trained mice to discriminate bilateral whisker deflections and report decisions by licking left or right. Two-photon calcium imaging revealed sparse coding of contralateral and ipsilateral whisker input in layer 2/3, with most neurons remaining silent during the task...
May 8, 2024: Neuron
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