Lynn Boschloo, Ella Bekhuis, Erica S Weitz, Mirjam Reijnders, Robert J DeRubeis, Sona Dimidjian, David L Dunner, Boadie W Dunlop, Ulrich Hegerl, Steven D Hollon, Robin B Jarrett, Sidney H Kennedy, Jeanne Miranda, David C Mohr, Anne D Simons, Gordon Parker, Frank Petrak, Stephan Herpertz, Lena C Quilty, A John Rush, Zindel V Segal, Jeffrey R Vittengl, Robert A Schoevers, Pim Cuijpers
A recent individual patient data meta-analysis showed that antidepressant medication is slightly more efficacious than cognitive behavioral therapy (CBT) in reducing overall depression severity in patients with a DSM-defined depressive disorder. We used an update of that dataset, based on seventeen randomized clinical trials, to examine the comparative efficacy of antidepressant medication vs. CBT in more detail by focusing on individual depressive symptoms as assessed with the 17-item Hamilton Rating Scale for Depression...
June 2019: World Psychiatry: Official Journal of the World Psychiatric Association (WPA)