Sylwia Mielcarska, Miriam Dawidowicz, Agnieszka Kula, Paweł Kiczmer, Hanna Skiba, Małgorzata Krygier, Magdalena Chrabańska, Jerzy Piecuch, Monika Szrot, Błażej Ochman, Julia Robotycka, Bogumiła Strzałkowska, Zenon Czuba, Dariusz Waniczek, Elżbieta Świętochowska
The study aimed to assess the expression of B7H3 concerning clinicopathological and histological parameters, including MSI/MSS status, CD-8 cells, tumour-infiltrating lymphocytes (TILs), budding, TNM scale and grading. Moreover, we analyzed the B7H3-related pathways using available online datasets and the immunological context of B7H3 expression, through the 48-cytokine screening panel of cancer tissues homogenates, immunogenic features and immune composition. The study included 158 patients diagnosed with CRC...
June 10, 2023: Cancers