Anaerobic threshold

Z V Morris, L M K Chin, L Chan, A A Guccione, A Ahmad, R E Keyser
While aerobic exercise training (AET) has generally been shown to improve 6-min walk test (6MWT) distance (6MWD) in patients with pulmonary hypertension (PH), a substantial number of patients appear to adapt differently, with minimal or even negative changes in 6MWT distance being reported. PURPOSE: To compare post-aerobic exercise training adaptations in cardiorespiratory functional capacity across three groups of patients with PH: those with high (HI), low (LI) and negative (NEG) post-training increases in 6MWD...
April 2020: Respiratory Medicine
Yuri Ichikawa, Tomoko Maeda, Tetsuya Takahashi, Kohei Ashikaga, Shiori Tanaka, Yuki Sumi, Haruki Itoh
AIMS: The kinetics of recovery-period oxygen uptake (VO2 ) are affected by the O2 deficit generated during exercise. However, studies using ramp tests (RTs) and constant work rate tests (CT) have differently characterized VO2 responses to increased exercise intensity differently. We used these two types of loading patterns to investigate the effects of low-intensity, medium-intensity, and high-intensity exercises on the half time (T1/2 ) of recovery-period VO2 and the mechanism. METHODS AND RESULTS: Ten healthy men aged 21...
March 25, 2020: ESC Heart Failure
Xiangfeng Li, Wenshuai Xu, Lu Zhang, Yi Zu, Yu Li, Yanli Yang, Ying Xiang, Yun Xiang, Ling Chen, Wei Liu, Lixia Chen, Kai-Feng Xu
OBJECTIVE: To evaluate the effects of yoga on exercise capacity and quality of life in patients with lymphangioleiomyomatosis (LAM), a rare cystic lung disease in women. PATIENTS AND METHODS: This was a nonrandomized, controlled study conducted in Beijing, China (August 27, 2017 - April 26, 2018). Twenty-six participants were allocated to the intervention (yoga) group (n = 13) or control group (n = 13). The yoga intervention involved a 24-week program of yoga class training for 90 min once a week and no fewer than 2 at-home sessions per week (at least 15 min per session)...
March 16, 2020: Orphanet Journal of Rare Diseases
Justine Schneider, Kathrin Schlüter, Tanja Sprave, Joachim Wiskemann, Friederike Rosenberger
PURPOSE: Most studies with cancer survivors use percentages of peak oxygen uptake (VO2peak ) for intensity prescription. Lactate or ventilatory thresholds might be useful submaximal alternatives, but this has never been investigated. Therefore, we aimed at comparing three training sessions prescribed using %VO2peak (reference), lactate thresholds, and ventilatory thresholds in terms of meeting the vigorous-intensity zone, physiological, and psychological responses. METHODS: Twenty breast (58 ± 10 years) and 20 prostate cancer survivors (68 ± 6 years), 3...
March 16, 2020: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Rudolf K F Oliveira, Aaron B Waxman, Paul J Hoover, Paul F Dellaripa, David M Systrom
BACKGROUND: Pulmonary hypertension (PH) adversely impact patient´s exercise capacity in interstitial lung disease (ILD). Pulmonary vascular and right ventricular (RV) dysfunction impact, however, have traditionally been thought to be mild, and clinically relevant principally in advanced lung disease states. We sought to evaluate the relative contributions of pulmonary mechanics, pulmonary vascular and RV function to the ILD exercise limit. METHODS: 49 ILD patients that underwent resting right heart catheterization followed by invasive exercise testing were evaluated...
March 12, 2020: Chest
Fernanda de Souza Nogueira Sardinha Mendes, Mauro Felippe Felix Mediano, Fernando Cesar de Castro E Souza, Paula Simplício da Silva, Fernanda Martins Carneiro, Marcelo Teixeira de Holanda, Roberto Magalhães Saraiva, Sergio Salles Xavier, Pedro Emmanuel Alvarenga Americano do Brasil, Andréa Silvestre de Sousa
Chagas heart disease (HD) is a chronic fibrosing myocarditis with high mortality. The PEACH study aimed to evaluate if exercise training can improve the functional capacity of Chagas HD patients with left ventricular dysfunction and/or heart failure. The PEACH study was a single center, parallel-group, clinical trial that randomized 30 clinical stable Chagas HD patients with left ventricular ejection fraction <45% or heart failure symptoms to either supervised exercise training 3 times/week for 6 months or a control group...
February 10, 2020: American Journal of Cardiology
T Badza, E H Tesfamariam, C G Cogger
Sludge recycling as an agricultural resource has gained great attention worldwide. This is exacerbated by the ever-rising municipal wastewater production and the realization of its potential as a soil amendment resource. Sludge suitability assessment and characterization is crucial to prompt informed decisions regarding its use on agricultural lands. Liquid sludge samples were collected from eighteen wastewater treatment plants (WWTPs) employing three different treatment processes in South Africa. Samples were analysed for physical and chemical parameters...
March 5, 2020: Science of the Total Environment
J E M Blackwell, B Doleman, C L Boereboom, A Morton, S Williams, P Atherton, K Smith, J P Williams, B E Phillips, J N Lund
OBJECTIVES: To assess the efficacy of high-intensity interval training (HIIT) for improving cardiorespiratory fitness (CRF) in patients awaiting resection for urological malignancy within four weeks. SUBJECTS/PATIENTS AND METHODS: A randomised control trial of consecutive patients aged (>65 years) scheduled for major urological surgery in a large secondary referral centre in a UK hospital. The primary outcome is change in anaerobic threshold (VO2AT ) following HIIT vs...
March 10, 2020: Prostate Cancer and Prostatic Diseases
Johan Moreau, Kathleen Lavastre, Huguette Romieu, Françoise Charbonnier, Sophie Guillaumont, Charlene Bredy, Hamouda Abassi, Oscar Werner, Gregoire De La Villeon, Anne Requirand, Annie Auer, Stefan Matecki, Clement Karsenty, Aitor Guitarte, Khaled Hadeed, Yves Dulac, Nathalie Souletie, Philippe Acar, Fanny Bajolle, Damien Bonnet, Laurence Negre-Pages, Thibault Mura, Maria Mounier, Pierre-Emmanuel Seguela, Julie Thomas, Xavier Iriart, Jean-Benoit-Thambo, Pascal Amedro
Background: Recent advances in the field of congenital heart disease (CHD) have significantly improved the overall prognosis. Now more attention is being given to health-related quality of life (HRQoL) and promotion of physical activity. Non-invasive relaxation therapy may be effective in cardiac patients concerned with exercise-induced dyspnoea. The SOPHROCARE randomised trial aims to assess the impact of Caycedian Sophrology on cardiopulmonary fitness in adolescents and young adults with CHD...
April 2020: IJC Heart & Vasculature
C Ren, W Zhao, T Shen, X Y Xu, L Q Zhou, L Y Tao, W Gao
Objective: To investigate the effects of ticagrelor on cardiorespiratory fitness in patients with coronary heart disease after percutaneous coronary intervention (PCI). Methods: A total of 1 073 patients, who were diagnosed as coronary heart disease and underwent cardiopulmonary exercise testing (CPET) within 1 year after PCI, were enrolled from September 2017 to September 2019 in Peking University Third Hospital, including 309 patients in ticagrelor group and 764 patients in clopidogrel group. Clinical information, blood test results, echocardiographic parameters, cardiorespiratory fitness related parameters (including peak oxygen uptake (VO(2)), anaerobic threshold VO(2), peak oxygen pulse (VO(2)/HR) and carbon dioxide ventilation equivalent (VE/VCO(2)) slope), coronary lesions and intervention information were obtained...
February 24, 2020: Zhonghua Xin Xue Guan Bing za Zhi
N Stephens, Matthew Wyon
AIMS: Musical theatre (MT) combines acting, singing, and dancing within a performance. The purpose of the current study was two-fold: 1) to report on the cardiorespiratory fitness of pre-professional MT dancers, and 2) to examine the cardiorespiratory demand of singing whilst dancing. METHODS: Twenty-one participants (16 females, 5 males; age 20±1.23 yrs; height 169.1±9.24 cm; weight 62.7±10.56) in their final year of pre-professional training volunteered for the study...
March 2020: Medical Problems of Performing Artists
Georgia Torres, Nigel John Crowther, Geoff Rogers
Background: Improvements in cardiorespiratory fitness attenuate the risk for metabolic syndrome (MetS). However, the determinants of cardiorespiratory fitness measurements such as oxygen consumption (VO2 ) peak and anaerobic threshold (AT) have not been investigated in persons with MetS. Therefore, the main aim of this study was to compare VO2 peak and AT between subjects with and without MetS and to investigate determinants of cardiorespiratory fitness and its effects on the odds for MetS and its individual components...
March 2, 2020: Metabolic Syndrome and related Disorders
Michel Silva Reis, Igor Nasser, Adriano Barroco, Danilo Cortozi Berton, José Alberto Neder, Ross Arena, Audrey Borghi-Silva
PURPOSE: The present study compared the level of agreement of anaerobic threshold (AT) between ventilatory and near-infrared spectroscopy (NIRS) techniques in patients with chronic heart failure (CHF) and healthy subjects. METHODS: Patients with CHF (n = 9) and a control group (CG; n = 14) underwent cardiopulmonary exercise testing on a cycle ergometer until physical exhaustion. Determination of AT was performed visually by (1) ventilatory-expired gas analysis curves and (2) oxyhemoglobin (O2Hb) and deoxyhemoglobin (HHb) curves assessed by NIRS...
March 2020: Journal of Cardiopulmonary Rehabilitation and Prevention
Jason Weatherald, Athénaïs Boucly, David Montani, Xavier Jaïs, Laurent Savale, Marc Humbert, Olivier Sitbon, Gilles Garcia, Pierantonio Laveneziana
BACKGROUND AND OBJECTIVE: Ventilatory inefficiency (high V'E /V'CO2 ) and resting hypocapnia are common in pulmonary vascular disease and are associated with poor prognosis. Low resting PaCO2 suggests increased chemosensitivity or an altered PaCO2 set-point. We aimed to determine the relationships between exercise gas exchange variables reflecting the PaCO2 set-point, exercise capacity, hemodynamics and V'E /V'CO2 . METHODS: Pulmonary arterial hypertension (n=34), chronic thromboembolic pulmonary hypertension (CTEPH, n=19) and pulmonary veno-occlusive disease (PVOD, n=6) patients underwent rest and peak exercise arterial blood gas measurements during cardiopulmonary exercise testing...
February 25, 2020: Archivos de Bronconeumología
Vladimir Grubelnik, Jan Zmazek, Rene Markovič, Marko Gosak, Marko Marhl
We present a mathematical model of the energy-driven metabolic switch for glucagon and insulin secretion from pancreatic alpha and beta cells, respectively. The energy status related to hormone secretion is studied for various glucose concentrations. Additionally, the physiological response is studied with regards to the presence of other metabolites, particularly the free-fatty acids. At low glucose, the ATP production in alpha cells is high due to free-fatty acids oxidation in mitochondria, which enables glucagon secretion...
February 25, 2020: Journal of Theoretical Biology
Ahmad Alkhatib, Min-Jung Hsieh, Chia-Hua Kuo, Chien-Wen Hou
PURPOSE: We investigated whether obesity adversities of excessive body fat, compensatory hyperinsulinemia, metabolic endotoxemia, irregular androgenicity, reduced cardiorespiratory and anaerobic fitness are ameliorated by high-intensity interval training (HIIT) with or without caffeine supplementation in women with obesity. METHODS: Twenty-four women with obesity (Asian cut-off point BMI ≥ 27 kg.m, body fat=40%) were evenly randomized to caffeine (CAF) and placebo (PLA) trials for an 8-week HIIT program (10x 1-min sprints, interspersed by 1-min rest)...
February 19, 2020: Medicine and Science in Sports and Exercise
Gabriela de Carvalho, Aline Gobbi, Ronaldo Bucken Gobbi, Damião Miranda Ngonga Alfredo, Thales Henrique do Carmo Furquim, Rafael Inácio Barbosa, Marcelo Papoti, Rinaldo Roberto de Jesus Guirro
Analyze the effects of sequential application of photobiomodulation therapy (PBMT) at different wavelengths on the performance of cycling athletes. Cyclists (48 male, mean age 33.77 years) underwent a performance evaluation through an incremental test, VO2max, blood lactate analysis, perception of effort, infrared thermography, and isokinetic evaluations. Photobiomodulation (180 J) with infrared (IR 940 ± 10 nm), red (RED 620 ± 10 nm), mixed Red, and IR (RED/IR 620 + 940 nm) or Sham (disabled device) intervention occurred on three consecutive days and was applied to the quadriceps femoris bilaterally...
February 20, 2020: Lasers in Medical Science
Ioana Mădălina Zota, Cristian Stătescu, Radu Andy Sascău, Mihai Roca, Radu Sebastian Gavril, Teodor Flaviu Vasilcu, Daniela Boișteanu, Alexandra Maștaleru, Alexandra Jitaru, Maria Magdalena Leon Constantin, Florin Mitu
Background and Objectives: Obstructive sleep apnea (OSA) is associated with daytime somnolence, cognitive impairment and high cardiovascular morbidity and mortality. Obesity, associated cardiovascular comorbidities, accelerated erythropoiesis and muscular mitochondrial energetic dysfunctions negatively influence exercise tolerance in moderate-severe OSA patients. The cardiopulmonary exercise testing (CPET) offers an integrated assessment of the individual's aerobic capacity and helps distinguish the main causes of exercise limitation...
February 15, 2020: Medicina
Boris Schmitz, Hannah Niehues, Lothar Thorwesten, Andreas Klose, Michael Krüger, Stefan-Martin Brand
Background: High-intensity interval training (HIIT) is a well-established training modality to improve aerobic and anaerobic capacity. However, sex-specific aspects of different HIIT protocols are incompletely understood. This study aimed to compare two HIIT protocols with different recovery periods in moderately trained females and males and to investigate whether sex affects high-intensity running speed and speed decrement. Methods: Fifty moderately trained participants (30 females and 20 males) performed an exercise field test and were randomized by lactate threshold (LT) to one of two time- and workload-matched training groups...
2020: Frontiers in Physiology
Yuta Takayanagi, Akira Koike, Hiroshi Kubota, Longmei Wu, Isao Nishi, Akira Sato, Kazutaka Aonuma, Yasushi Kawakami, Masaki Ieda
The pulse wave transit time (PWTT) is easily measured as the time from the R wave of an electrocardiogram to the arrival of the pulse wave measured by an oxygen saturation monitor at the earlobe. We investigated whether the change of PWTT during exercise testing reflects cardiopulmonary function. Eighty-nine cardiac patients who underwent cardiopulmonary exercise testing (CPX) were enrolled. We analyzed the change of PWTT during exercise and the relationship between the shortening of the PWTT and CPX parameters...
February 17, 2020: Drug Discoveries & Therapeutics
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