Kun Zhao, Hui Zhang, Jianyang Lin, Shoucheng Xu, Jianzhi Liu, Xianjing Qian, Yongbing Gu, Guoqiang Ren, Xinyu Lu, Baomin Chen, Deng Chen, Jun Yan, Jichun Ma, Wenxiang Wei, Yuanwei Wang
OJECTIVES: Low-grade glioma (LGG) is associated with increased mortality owing to recrudescence and the tendency for malignant transformation. Therefore, it is imperative to discover novel prognostic biomarkers as existing traditional prognostic biomarkers of glioma, including clinicopathological features and imaging examinations, are unable to meet the clinical demand for precision medicine. Accordingly, we aimed to evaluate the prognostic value of cyclin D1 (CCND1) expression levels and construct radiomic models to predict these levels in patients with LGG MATERIALS AND METHODS: A total of 412 LGG cases from The Cancer Genome Atlas (TCGA) were used for gene-based prognostic analysis...
May 31, 2024: Academic Radiology