Xiang Li, Yun Du, Jiang-Feng Huang, Wen-Wei Li, Wei Song, Ruo-Nan Fan, Hua Zhou, Tao Jiang, Chang-Geng Lu, Zhuang Guan, Xiao-Fei Wang, Hui Gong, Xiang-Ning Li, Anan Li, Ling Fu, Yan-Gang Sun
Knowledge about the neuronal dynamics and the projectome are both essential for understanding how the neuronal network functions in concert. However, it remains challenging to obtain the neural activity and the brain-wide projectome for the same neurons, especially for neurons in subcortical brain regions. Here, by combining in vivo microscopy and high-definition fluorescence micro-optical sectioning tomography, we have developed strategies for mapping the brain-wide projectome of functionally relevant neurons in the somatosensory cortex, the dorsal hippocampus, and the substantia nigra pars compacta...
May 31, 2024: Neuroscience Bulletin