high altitud and training

Alexander Egger, Maximilian Niederer, Katharina Tscherny, Josef Burger, Verena Fuhrmann, Calvin Kienbacher, Dominik Roth, Wolfgang Schreiber, Harald Herkner
BACKGROUND: High quality cardiopulmonary resuscitation is a key factor in survival with good overall quality of life after out-of-hospital cardiac arrest. Current evidence is predominantly based on studies conducted at low altitude, and do not take into account the special circumstances of alpine rescue missions. We therefore aimed to investigate the influence of physical strain at high altitude on the quality of cardiopulmonary resuscitation. METHODS: Alpine field study...
March 6, 2020: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Mary E Crocker, Shakir Hossen, Dina Goodman, Suzanne M Simkovich, Miles Kirby, Lisa M Thompson, Ghislaine Rosa, Sarada S Garg, Gurusamy Thangavel, Eric D McCollum, Jennifer Peel, Thomas Clasen, William Checkley
BACKGROUND: In resource-limited settings, pneumonia diagnosis and management are based on thresholds for respiratory rate (RR) and oxyhaemoglobin saturation (SpO2 ) recommended by WHO. However, as RR increases and SpO2 decreases with elevation, these thresholds might not be applicable at all altitudes. We sought to determine upper thresholds for RR and lower thresholds for SpO2 by age and altitude at four sites, with altitudes ranging from sea level to 4348 m. METHODS: In this cross-sectional study, we enrolled healthy children aged 0-23 months who lived within the study areas in India, Guatemala, Rwanda, and Peru...
March 2020: Lancet Global Health
S N Nisha, A S Fathinul Fikri, A R Aida, M Salasiah, S Hamed, T Rohit, A R Amei Farina, J L Loh, M Mazlyfarina, S Subapriya
OBJECTIVE: To identify regions of the brain affected during cognitive working memory during tasks to assess attention, planning and decision making among military aviation personnel who have chronic intermittent exposure to high altitude environment. METHOD: A case-control study was conducted in the Universiti Putra Malaysia among eight military personnel, four of whom had chronic intermittent exposure to high altitude training. They were divided into two groups, chronic intermittent exposure group (CE) (n=4) and a control group (n=4)...
January 2020: Medical Journal of Malaysia
Martin Faulhaber, Stephan Pramsohler, Linda Rausch, Verena Menz
Faulhaber, Martin, Stephan Pramsohler, Linda Rausch, and Verena Menz. Cardiorespiratory and metabolic responses during graded exercise in normobaric and hypobaric hypoxia. High Alt Med Biol. 00:000-000, 2019. Background: The study investigated submaximal exercise responses during an acute exposure to normobaric hypoxia (NH) versus hypobaric hypoxia (HH) focusing on different exercise intensities. Methods: Eight recreationally trained male subjects (age 23 ± 3 years) performed submaximal cycling exercise at three different intensity levels (100, 150, and 200 W) in NH (simulated altitude 3150 m) and HH (terrestrial high altitude, 3150 m) in a cross-over study design...
January 10, 2020: High Altitude Medicine & Biology
Aida Carballo-Fazanes, Roberto Barcala-Furelos, Juan Eiroa-Bermúdez, María Fernández-Méndez, Cristian Abelairas-Gómez, Santiago Martínez-Isasi, Manuel Murciano, Felipe Fernández-Méndez, Antonio Rodríguez-Núñez
AIM: To analyse the effect of oxygen fraction reduction (O2 14%, equivalent to 3250 m) on Q-CPR and rescuers' physiological demands. METHODOLOGY: A quasi-experimental study was carried out in a sample of 9 Q-CPR proficient health care professionals. Participants, in teams of 2 people, performed 10 min CPR on a Laerdal ResusciAnne mannequin (30:2 compression/ventilation ratio and alternating roles between rescuers every 2 min) in two simulated settings: T21-CPR at sea level (FiO2 of 21%) and T14 - CPR at 3250 m altitude (FiO2 of 14%)...
December 24, 2019: American Journal of Emergency Medicine
Sven Christian Voss, Khalifa Al-Hamad, Waseem Samsam, Anissa Cherif, Costas Georgakopoulos, Mohammed Al Maadheed, George Balanos, Sam Lucas, Pierre-Edouard Sottas, Mathew Wilson, Nathan Townsend
Exposure to either natural or simulated hypoxia induces hematological adaptations that may affect the parameters of the Athlete Biological Passport (ABP). The aim of the present study was to examine the effect of a novel, mixed hypoxic dose protocol on the likelihood of producing an atypical ABP finding. Ten well-trained middle-distance runners participated in a "live high, train low and high" (LHTLH) altitude training camp for 14 days. The participants spent ˜6 hr.d-1 at 3000-5400 m during waking hours and ˜10 h...
December 30, 2019: Drug Testing and Analysis
Mahdi Sareban, Lisa M Schiefer, Franziska Macholz, Larissa Schäfer, Quirin Zangl, Franciscus Inama, Bernhard Reich, Barbara Mayr, Peter Schmidt, Arnulf Hartl, Peter Bärtsch, Josef Niebauer, Gunnar Treff, Marc M Berger
INTRODUCTION: Acute mountain sickness (AMS) may develop in non-acclimatized individuals after exposure to altitudes ≥2500m. Anecdotal reports suggest that endurance trained (ET) athletes with a high maximal oxygen uptake (VO2max) may be at increased risk for AMS. Possible underlying mechanisms include a training-induced increase in resting parasympathetic activity, higher resting metabolic rate (RMR), and lower hypoxic ventilatory response (HVR). METHODS: In 38 healthy, non-acclimatized men (19 ET and 19 untrained controls (UT), VO2max 66±6 vs...
December 23, 2019: Medicine and Science in Sports and Exercise
Ru-Nan Zhao, Qian-Qian He, Xiao-Jie Chu, Zhi-Qiang Lu, Zun-Ling Zhu
Climate change seriously affects the geographical distribution of plants. Regional diffe-rences in plant response to climate change will provide important guidance for species introduction and conservation. Based on ArcGIS and MaxEnt model, we used 176 geographic information of Carpinus cordata and 13 climatic variables to reconstruct its current and future niche. The results showed that the model had a high credibility in simulating contemporary potential distribution areas. The AUC values of the test set and the training set of the model were 0...
November 2019: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
Ana I de Castro, Pilar Rallo, María Paz Suárez, Jorge Torres-Sánchez, Laura Casanova, Francisco M Jiménez-Brenes, Ana Morales-Sillero, María Rocío Jiménez, Francisca López-Granados
The need for the olive farm modernization have encouraged the research of more efficient crop management strategies through cross-breeding programs to release new olive cultivars more suitable for mechanization and use in intensive orchards, with high quality production and resistance to biotic and abiotic stresses. The advancement of breeding programs are hampered by the lack of efficient phenotyping methods to quickly and accurately acquire crop traits such as morphological attributes (tree vigor and vegetative growth habits), which are key to identify desirable genotypes as early as possible...
2019: Frontiers in Plant Science
Bernard Bett, Delia Grace, Hu Suk Lee, Johanna Lindahl, Hung Nguyen-Viet, Pham-Duc Phuc, Nguyen Huu Quyen, Tran Anh Tu, Tran Dac Phu, Dang Quang Tan, Vu Sinh Nam
BACKGROUND: Dengue fever is the most widespread infectious disease of humans transmitted by Aedes mosquitoes. It is the leading cause of hospitalization and death in children in the Southeast Asia and western Pacific regions. We analyzed surveillance records from health centers in Vietnam collected between 2001-2012 to determine seasonal trends, develop risk maps and an incidence forecasting model. METHODS: The data were analyzed using a hierarchical spatial Bayesian model that approximates its posterior parameter distributions using the integrated Laplace approximation algorithm (INLA)...
2019: PloS One
Trent Stellingwerff, Peter Peeling, Laura A Garvican-Lewis, Rebecca Hall, Anu E Koivisto, Ida A Heikura, Louise M Burke
Training at low to moderate altitudes (~ 1600-2400 m) is a common approach used by endurance athletes to provide a distinctive environmental stressor to augment training stimulus in the anticipation of increasing subsequent altitude- and sea-level-based performance. Despite some scientific progress being made on the impact of various nutrition-related changes in physiology and associated interventions at mountaineering altitudes (> 3000 m), the impact of nutrition and/or supplements on further optimization of these hypoxic adaptations at low-moderate altitudes is only an emerging topic...
December 2019: Sports Medicine
Atef M Ghaleb, Mohamed Z Ramadan, Ahmed Badwelan, Khalid Saad Aljaloud
OBJECTIVE: The purpose of this study was to evaluate the lifting capabilities of individuals in hypoxia when they wear different types of safety shoes and to investigate the behavior of the physiological responses induced by the lifting process associated with those variables. METHODS: An experimental design was used, based on two sessions. The first was training and acclimatization session, then an experimental lifting phase. A total of ten male students of King Saud University were recruited in the study...
October 29, 2019: International Journal of Environmental Research and Public Health
Hui Yuan, Yong Wang, Peng-Fei Liu, Yun-Long Yue, Jin-Song Guo, Zhen-Chang Wang
BACKGROUND: Hypobaric hypoxia (HH) exposure at high altitudes can result in a decline in cognitive function, which may have a serious impact on the daily life of people who migrate to high altitudes. However, the specific HH-induced changes in brain function remain unclear. This study explored changes in brain activity in rats exposed to a sustained HH environment using functional magnetic resonance imaging (fMRI). METHODS: Healthy male rats (8 weeks old) were randomly divided into a model group and a control group...
October 22, 2019: Chinese Medical Journal
Bipul Neupane, Teerayut Horanont, Nguyen Duy Hung
The production of banana-one of the highly consumed fruits-is highly affected due to loss of certain number of banana plants in an early phase of vegetation. This affects the ability of farmers to forecast and estimate the production of banana. In this paper, we propose a deep learning (DL) based method to precisely detect and count banana plants on a farm exclusive of other plants, using high resolution RGB aerial images collected from Unmanned Aerial Vehicle (UAV). An attempt to detect the plants on the normal RGB images resulted less than 78...
2019: PloS One
Xin Dong, Yuan-Meng-Ran Chu, Xiaodong Gu, Qiongyu Huang, Jindong Zhang, Wenke Bai
As an endemic primate species with one of the highest priorities in wildlife conservation in China, Sichuan snub-nosed monkeys (Rhinopithecus roxellana) have undergone a sharp decline and range reduction in recent centuries. Here, we used maximum entropy modelling (MaxEnt) integrated with four types of environmental variables, including three biological climate variables (Bio17, precipitation of the driest quarter; Bio6, min. temperature of the coldest month; and Bio2, mean diurnal range), three topographic variables (altitude, slope, and aspect), two anthropogenic variables (Human Footprint Index and human disturbance), and three vegetation-related variables (enhanced vegetation index, normalized difference vegetation index, and Wet Index) to identify the spatial distribution of suitable habitats for Sichuan snub-nosed monkeys in Baihe Nature Reserve (BNR), which is located in the Minshan Mountains...
October 11, 2019: Environmental Science and Pollution Research International
Linjia Wang, Simin Yang, Lu Yan, Hao Wei, Jianxiong Wang, Siwang Yu, Ah-Ng Tony Kong, Ying Zhang
Elite endurance athletes are used to train under hypoxic/high altitude conditions, which can elicit certain stress responses in skeletal muscle and helps to improve their physical performance. Nuclear factor erythroid 2-related factor 2 (Nrf2) regulates the cellular redox homoeostasis and metabolism in skeletal muscle, playing important roles in adaptation to various stresses. In this study, Nrf2 knockout (KO) and wild-type (WT) mice were pre-conditioned to 48 hours of hypoxia exposure (11.2% oxygen), and the effects of hypoxia preconditioning (HP) on exercise capacity and exercise-induced changes of antioxidant status, energetic metabolism and mitochondrial adaptation in skeletal muscle were evaluated...
September 5, 2019: Journal of Applied Physiology
Jessica U Meir, Julia M York, Bev A Chua, Wilhelmina Jardine, Lucy A Hawkes, William K Milsom
The bar-headed goose is famed for migratory flight at extreme altitude. To better understand the physiology underlying this remarkable behavior, we imprinted and trained geese, collecting the first cardiorespiratory measurements of bar-headed geese flying at simulated altitude in a wind tunnel. Metabolic rate during flight increased 16-fold from rest, supported by an increase in the estimated amount of O2 transported per heartbeat and a modest increase in heart rate. The geese appear to have ample cardiac reserves, as heart rate during hypoxic flights was not higher than in normoxic flights...
September 3, 2019: ELife
Behnam Meshgi, Morteza Majidi-Rad, Ahmad Ali Hanafi-Bojd, Ali Kazemzadeh
Dicrocoeliasisis caused by the small liver fluke (Dicrocoelium spp.), mainly Dicrocoelium dendriticum in domestic and wild ruminants. The small liver fluke is the probable predisposing cause of economic burden. The impact of geographic and climatic factors on the incidence of dicrocoeliasis has been severely ignored in different geographical areas. Due to the lack of data regarding dicrocoeliasis in Iran, this study was aimed to investigate the prevalence and intensity of ovine and bovine Dicrocoelium infection in the coastal strip south of the Caspian Sea...
July 12, 2019: Preventive Veterinary Medicine
Tao Shen, Hong Yu, Yuan Zhong Wang
Based on the species distribution data provided by the National Specimen Information Infrastructure combined with field survey and MaxEnt model, we simulated and verified the suitable distribution area of Gentiana rigescens. Furthermore, the relationship between the geographical distribution and climatic factors of G. rigescens was analyzed. The results showed that area under curve of training set and test set were more than 0.90, indicating high prediction precision and accurate prediction results. Geographic coordinate range of G...
July 2019: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
Melissa L Coleman
The space race began in the summer of 1955 when the United States and the Soviet Union pledged to launch artificial satellites. The race culminated in 1969 when the United States landed the first humans on the moon. After completing his training in anesthesiology, Dr. Cloid Green forged his career as one of the physician-scientists who played an integral role by evaluating the effects of space flight on human physiology. Family members of Dr. Green were interviewed and university and society archives, literature and periodicals were reviewed...
April 2019: Journal of Anesthesia History
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