keyword
https://read.qxmd.com/read/37038291/covid-19-prevention-and-treatment-by-targeting-fc-fusion-proteins-an-experience-to-fight-emerging-diseases
#21
JOURNAL ARTICLE
Hamed Zare, Tahereh Farkhondeh, Hamid Bakherad, Hengame Sharifi, Maryam Hosseinzade Shirzeyli, Saeed Samarghandian, Fahimeh Ghasemi
The coronavirus disease 2019 (Covid-19) pandemic has been considered a major threat to human health. Effective therapeutic approaches are urgently required. Spike protein and the Angiotensin-converting enzyme 2 (ACE2) receptors have critical roles in SARS-CoV-2 infection. As a result, these two proteins are considered potential targets for the development of a wide variety of biotherapeutics and vaccines for controlling Covid-19. The fusion proteins have desirable medicinal properties, including high serum half-life, stability, and solubility in the body...
April 10, 2023: Current Molecular Medicine
https://read.qxmd.com/read/36872833/evaluation-of-general-health-exposure-to-workplace-violence-and-predicting-its-consequences-in-health-care-employees-in-iran
#22
JOURNAL ARTICLE
Ali Asghar Sajedian, Hamed Akbari, Esfandiar Azad, Vahid Ahmadi Moshiran, Mohsen Sadeghi-Yarandi, Mohammad Ghasemi
BACKGROUND: Workplace violence is an important event that affects the safety of healthcare employees, and diagnosing it in hospitals is an immediate occupational concern. OBJECTIVE: The present study was conducted to investigate general health and the prevalence of occupational violence and to predict its consequences among nurses and paramedics as the main body in medical settings. METHODS: This cross-sectional study was performed in 2020 in a selected hospital in Tehran, Iran...
February 27, 2023: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://read.qxmd.com/read/36796439/soluble-fiber-supplementation-and-serum-lipid-profile-a-systematic-review-and-dose-response-meta-analysis-of-randomized-controlled-trials
#23
REVIEW
Abed Ghavami, Rahele Ziaei, Sepide Talebi, Hanieh Barghchi, Elyas Nattagh-Eshtivani, Sajjad Moradi, Pegah Rahbarinejad, Hamed Mohammadi, Hatav Ghasemi-Tehrani, Wolfgang Marx, Gholamreza Askari
To present a comprehensive synthesis of the effect of soluble fiber supplementation on blood lipid parameters in adults, a systematic search was undertaken in PubMed, Scopus, and ISI Web of Science of relevant articles published before November 2021. Randomized controlled trials (RCTs) evaluating the effects of soluble fibers on blood lipids in adults were included. We estimated the change in blood lipids for each 5 g/d increment in soluble fiber supplementation in each trial and then calculated the mean difference (MD) and 95% CI using a random-effects model...
February 2, 2023: Advances in Nutrition
https://read.qxmd.com/read/36668675/serological-evidence-of-yersinia-pestis-infection-in-rodents-and-carnivores-in-northwestern-iran
#24
JOURNAL ARTICLE
Saber Esmaeili, Parisa Esmaeili, Ahmad Mahmoudi, Ahmad Ghasemi, Ali Mohammadi, Amin Bagheri, Aria Sohrabi, Farshid Rezaei, Hamed Hanifi, Amir Hesam Neamati, Mohammad Mehdi Gouya, Ehsan Mostafavi
BACKGROUND: Plague may recur after several decades in its endemic regions; therefore, the continuous monitoring of wildlife is essential, even when no human cases are reported in the old foci. The present study was conducted to monitor rodents and their ectoparasites as well as carnivores to learn about the epidemiology of plague infection in an old focus of Iran. METHODOLOGY: The present study was conducted from 2019 to 2020 in Takestan county of Qazvin Province in northwestern Iran...
January 2023: PLoS Neglected Tropical Diseases
https://read.qxmd.com/read/36584195/problematic-internet-use-and-safety-behavior-the-moderating-role-of-safety-climate
#25
JOURNAL ARTICLE
Fakhradin Ghasemi, Hamed Aghaei, Asghar Nikravesh
Problematic internet use (PIU) can cause mental and physical harm to individuals and may be an emerging factor contributing to unsafe work behavior. In this study, the relationship between PIU and safety behavior was investigated. Moreover, it was hypothesized that safety climate can moderate the relationship between PIU and safety behavior. Participants were employees from a mining industry in Iran. Three validated questionnaires were distributed to gather the required data regarding PIU, safety climate, and safety behavior...
2022: PloS One
https://read.qxmd.com/read/36550335/effects-of-cem-cement-and-emdogain-on-proliferation-and-differentiation-of-human-stem-cells-from-the-apical-papilla-a-comparative-in-vitro-study
#26
JOURNAL ARTICLE
Elham Khoshbin, Leila Ghasemi, Rezvan Najafi, Hamed Karkehabadi
OBJECTIVES: This study compared the effects of calcium-enriched mixture (CEM) cement, Emdogain (EMD), and their combination (CEM/Emdogain) on the differentiation and proliferation of stem cells from the apical papilla (SCAPs). METHODS: In this in vitro, experimental study, SCAPs were isolated from two sound immature impacted third molars and cultured. After ensuring their stemness by detecting cell surface markers they were exposed to CEM cement, Emdogain, and CEM cement coated with Emdogain for 24 and 72 h...
January 2023: Biotechnology Letters
https://read.qxmd.com/read/36511374/risk-taking-behaviors-considering-internet-gaming-disorder-among-iranian-university-students-a-latent-class-analysis
#27
JOURNAL ARTICLE
Faeze Ghasemi Seproo, Leila Janani, Seyed Abbas Motevalian, Abbas Abbasi-Ghahramanloo, Hamed Fattahi, Shahnaz Rimaz
BACKGROUND: Dangerous behaviors adversely affect the health of adolescents and young adults. This study aimed to identify the subgroups of college students based on the parameters of risky behavior and analyze the impact of demographic factors and internet gaming disorder (IGD) belonging to each class. STUDY DESIGN: A cross-sectional study. METHODS: The study was conducted on 1355 students through a multi-stage random sampling method in 2020...
October 19, 2022: Journal of Research in Health Sciences
https://read.qxmd.com/read/36450401/2022-canadian-surgery-forum-sept-15-17-2022-abstracts-presented-at-the-2022-canadian-surgery-forum-in-toronto-ontario
#28
JOURNAL ARTICLE
Yasser Selim, Élise Di Lena, Nadia Safa, Sid Rahman, Pepa Kaneva, Liane Feldman, Nawaf Abu-Omar, Zarrukh Baig, Nathan Ginther, Dilip Gill, Zarrukh Baig, Zaini Sarwar, Carlos Verdiales, Mike Moser, Kevin Verhoeff, Valentin Mocanu, Breanna Fang, Jerry Dang, Warren Sun, Noah Switzer, Daniel Birch, Shahzeer Karmali, Julie La, Anood Alqaydi, Xuejiao Wei, Genevieve Digby, Susan Brogly, Shaila Merchant, Kieran Purich, Kevin Verhoeff, Alexander Miles, Janice Y Kung, A M James Shapiro, David L Bigam, Samantha Albacete, Ashlee Matkin, Danielle Dumestre, Lashan Peiris, Rahim Valji, Simon Turner, Kieran Purich, Kevin Verhoeff, Brett Mador, Steffane McLennan, Ali Safar, Atif Jastaniah, Morgan Schellenberg, Natthida Owattanapanich, Areg Grigorian, Lydia Lam, Jeffry Nahmias, Kenji Inaba, Morgan Schellenberg, Panagiotis Liasidis, Kenji Inaba, Demetrios Demetriades, Morgan Schellenberg, Elizabeth R Benjamin, Shaun Cowan, Natthida Owattanapanich, Monica D Wong, Kenji Inaba, Demetrios Demetriades, Morgan Schellenberg, Natthida Owattanapanich, Brent Emigh, Lindsey Karavites, Damon H Clark, Lydia Lam, Kenji Inaba, Morgan Schellenberg, Elizabeth R Benjamin, Natthida Owattanapanich, Kenji Inaba, Demetrios Demetriades, Morgan Schellenberg, Geoffrey A Anderson, Natthida Owattanapanich, Vincent Cheng, Lydia Lam, Kenji Inaba, Lee Myers, Julian Daza, Brian Cuthbertson, Paul Myles, Mark Shulman, Duminda Wijeysundera, Lyndsay T Glass, Patrick B Murphy, Laura Allen, Kathryn Minkhorst, Dillon Bowker, Ephraim S Tang, Kenneth Leslie, Jeffrey E Hawel, Kevin Verhoeff, Odelle Ma, Kieran Purich, Samuel Skinner, Raveena Dhaliwal, Matt Strickland, Garrett Johnson, Jason Park, Ashley Vergis, Lawrence Gillman, Justin Rivard, Keegan Guidolin, Justin Lin, Anudari Zorigtbaatar, Minahil Nadeem, Tarek Ibrahim, Zdenka Neilson, Kyung Young Peter Kim, Luckshi Rajendran, Sami Chadi, Fayez Quereshy, Lyndsay T Glass, Malcolm Davidson, Emily Friedrich, Caitlin Champion, Saba Balvardi, Koorosh Semsar-Kazerooni, Pepa Kaneva, Carmen Mueller, Melina Vassiliou, Mohammed Al Mahroos, Julio Fiore, Kevin Schwartzman, Liane Feldman, Nada Gawad, Kieran Purich, Kevin Verhoeff, Blaire Anderson, Tyler McKechnie, Ryan Daniel, Colin Kruse, Marc Levin, Yung Lee, Aristithes Doumouras, Dennis Hong, Cagla Eskicioglu, Tyler McKechnie, Christopher Povolo, Jay Lee, Yung Lee, Lily Park, Aristithes Doumouras, Dennis Hong, Mohit Bhandari, Cagla Eskicioglu, Kieran Purich, Esther Lee, Kevin Verhoeff, Dasan Sydora, Simon Turner, Matt Strickland, Jessica Henley, Darrell Boone, Stephanie Roberts, Emma Imbert, Duncan McGrouther, Paul Manuel, Christine Li, Mark Dykstra, Haili Wang, Ryan Snelgrove, Samuel Skinner, Kevin Verhoeff, Kieran Purich, Troy Perry, Matthew Strickland, Raveena Dhaliwal, Tori Lenet, Stephanie Skanes, Joseph Tropiano, Daniel McIsaac, Alan Tinmouth, Julie Hallet, Stuart Nicholls, Dean Fergusson, Guillaume Martel, Tori Lenet, Joseph Tropiano, Stephanie Skanes, Victoria Ivankovic, Daniel McIsaac, Alan Tinmouth, Andrea Patey, Dean Fergusson, Guillaume Martel, Jeff Metz, Reza Naqvi, Ruediger Noppens, Jeff Hawel, Ahmad Elnahas, Christopher Schlachta, Nawar Alkhamesi, Hilalion San Ahn, Tori Lenet, Richard Gilbert, Ranjeeta Mallick, Julie Shaw, Daniel McIsaac, Guillaume Martel, Uyen Do, Makena Pook, Tahereh Najafi, Fateme Rajabiyazdi, Charbel El-Kefraoui, Saba Balvardi, Natasha Barone, Hiba Elhaj, Philip Nguyen-Powanda, Lawrence Lee, Gabriele Baldini, Liane Feldman, Julio Fiore, Armin Rouhi, Kieran Purich, Uzair Jogiat, Deng Mapiour, Michael Kim, Brianna Greenberg, Ashlie Nadler, Hala Muaddi, Theres Stukel, Charles De Mestral, Avery Nathens, Stephen Pautler, Bobby Shayegan, Wael Hanna, Christopher Schlachta, Rodney Breau, Laura Hopkins, Timothy Jackson, Paul Karanicolas, Lily Park, Christopher Griffiths, Sam Ali, Victoria Archer, Zacharie Cloutier, Dexter Choi, Tyler McKechnie, Pablo Serrano, Kelly Vogt, J Andrew McClure, Philip Jones, Marko Mrkobrada, Suzanne Flier, Blayne Welk, Luc Dubois, Nori Bradley, Kosar Khwaja, Laura Allen, Lily Tung, Morad Hameed, Karina Spoyalo, Jacinthe Lampron, Carlos Garcia-Ochoa, Atif Jastaniah, Paul Engels, Gaurav Talwar, Zacharie Cloutier, Sam Minor, Brad Moffat, Neil Parry, Kelly Vogt, Shirley Xiaoxuan Deng, Tega Ebeye, Bree T Sharma, Anas Samman, Amna Zulfiqar, Roderick H Purzner, Brittany Greene, Melanie Tsang, Shiva Jayaraman, Patrick Murphy, Laura Allen, Chad G Ball, Morad Hameed, Paul Engels, Rahima Nenshi, Sandy Widder, Sam Minor, Neil Parry, Nori Bradley, Brad Moffat, Kelly Vogt, Mostafa Alhabboubi, Sender Liberman, Evan Wong, Talat Chughtai, Joel Turner, Jessica Lie, Sam Wiseman, Jennifer Li, Nicole Mak, Simon Laplante, Babak Namazi, Parmiss Kiani, Daniel Hashimoto, Adnan Alseidi, Mauricio Pasten, L Michael Brunt, Sujata Gill, Brian Davis, Matthew Bloom, Luise Pernar, Allan Okrainec, Amin Madani, Jessica Lie, Trevor Hamilton, Kylie Nabata, Jenny W Zhang, Darren Zhao, Phil Dawe, Morad Hameed, Jeremy Drung, Laura Allen, Ken Leslie, Jeremy Drung, Thomas Nixon, Kieran Purich, Kevin Verhoeff, Samuel Skinner, Raveena Dhaliwal, Matt Strickland, Alexandra Allard-Coutu, Barbara Heller, Victoria Wright, Wanjae Cho, Michael Wong, Kevin Singh, Sarah Mansouri, Émilie Comeau, Yves Collin, Sonia Cheng Oviedo, Alex Lee, Luckshi Rajendran, Tyler Lamb, Morgann Reid, Anastasia Turner, Kimberly Bertens, Janelle Rekman, Fady Balaa, Jillian Tweedy, Katerina Neumann, Geoff Porter, Michael A D'Elia, Iris Teo, Catherine L Forse, Reilly Musselman, Brent Hopkins, Lily Grozman, Nawaf Alshawan, Shannon Fraser, Simon Bergman, Jean-Sebastien Pelletier, Tsafrir Vanounou, Evan G Wong, Ananya Srivastava, Brodie Nolan, Lyon Qiao, James Jung, Kameela Alibhai, Isabelle Raîche, Heather McDonald, Nada Gawad, Christina Lee, Rona Cheifetz, Philippa Hawley, Jeongyoon Jenny Moon, Zachary Rehany, Mehrshad Bakhshi, Tarek Razek, Jeremy Grushka, Nathalie Boulanger, Larry Watt, Alexandra Vivier, Greg Clark, Paola Fata, Dan Deckelbaum, Kosar Khwaja, Atif Jastaniah, Evan Wong, Nathan How, Kevin Ren, Yuan Qiu, Karyssa Hamann, Karina Spoyalo, Annie Lalande, Andrea MacNeill, Jason Park, Annie Lalande, Stephanie Alexis, Karina Spoyalo, Keiko Patterson, Neha Gadhari, Jiaying Zhao, Andrea MacNeill, Zarrukh Baig, Rubia Ahmed, Ameer Farooq, Ahmer Karimuddin, Christina Schweitzer, Sam Wiseman, Joshua Keogh, Allison Chhor, Housne Begum, Noori Akhtar-Danesh, Christian Finley, Bright Huo, Daria Manos, Zhaolin Xu, Kara Matheson, Samuel Chun, John Fris, Alison Wallace, Daniel French, Yogita S Patel, Jean-Marc Baste, Yaron Shargall, Thomas K Waddell, Kazuhiro Yasufuku, Tiago N Machuca, Feng Xie, Lehana Thabane, Wael C Hanna, Yogita S Patel, Marla K Beauchamp, Joshua Wald, Lawrence Mbuagbaw, Brenda L Key, Sheryl M Green, Wael C Hanna, Uzair Jogiat, Abdollah Behzadi, Laura Donahoe, Awrad Nasralla, Julius Poon, Najib Safieddine, Nazgol Seyednejad, Iran Tavakoli, Simon Turner, Anna L McGuire, Sohat Sharma, Roy A Hilzenrat, Melissa McConechy, Ingrid Frank, Curtis Hughsman, Stephen Yip, James J Choi, John Yee, Uzair Jogiat, Hannah Sasewich, Simon Turner, Vickie Baracos, Dean Eurich, Heather Filafilo, Eric Bedard, Yung Lee, Yasith Samarasinghe, Janhavi Patel, Adree Khondker, Tyler McKechnie, Nadeesha Samarasinghe, Christian Finley, Wael Hanna, Yaron Shargall, John Agzarian, Evan Barber, Melissa Whidden, Francisco Aguirre, Andrew Graham, Gileh-Gol Akhtar-Danesh, Allison Chhor, Housne Begum, Joycelyne Ewusie, Lawrence Mbuagbaw, Shargall Yaron, Adom Bondzi-Simpson, Melanie Keshishi, Yonas Ademe, Ayalew Tizazu, Marci Rose, Sameena Uddin, Michael Ko, Riley Bowker, Jimmy Ddamba, Daniel French, Alison Wallace, Negar Ahmadi, Najib Safieddine, Sayf Gazala, Carmine Simone, Sami A Abdul, Frances Wright, Christian Finley, Patrick J Villeneuve, Sebastian Gilbert, Sudhir Sundaresan, Andrew J E Seely, Donna E Maziak, Pooja Patel, Daria Manos, Alison Wallace, Madelaine Plourde, Lyndsay Harrison, Donna Turner, Jolie Ringash, Douglas Manuel, Biniam Kidane, Vaibhav Gupta, Kathleen Decker, Laura Davis, Gail Darling, Carolyn Compton, Natalie Coburn, Randy Boyes, Michael Pugliese, Alyson Mahar, Amy Hsu, Ge Shi, Andrew Kokavec, Edward Ho, Ryan Waterman, Edward Wang, Kiera Harnden, Richard Malthaner, Rahul Nayak, Mehdi Qiabi, Ge Shi, Richard Malthaner, Rahul Nayak, Mehdi Qiabi, Jacob A Alaichi, Yogita Patel, Forough Farrokhyar, Marko Simunovic, Wael C Hanna, Biniam Kidane, Stephen Gowing, Richard Liu, Sadeesh Srinathan, Larry Tan, Linda Chang Qu, Richard Malthaner, Jacob Alaichi, Peter Malik, Yogita Patel, Wael Hanna, Emily Mackay, Umeed Fahim, Ajmal Hafizi, Ahmad S Ashrafi, Jay Lee, Tyler McKechnie, Nalin Amin, Aristithes Doumouras, Dennis Hong, Cagla Eskicioglu, Kieran Purich, Courtney Streu, Clarence Wong, Dan Schiller, Matthew Castelo, Colin Sue-Chue-Lam, Lawrence Paszat, Adena Scheer, Bettina Hansen, Teruko Kishibe, Nancy Baxter, Antonio Caycedo-Marulanda, Emma Neary, Tarek Ibrahim, Chris Verschoor, Sunil Patel, Shaila Merchant, Sami Chadi, Luis Romagnolo, Antonio Caycedo-Marulanda, Chris Verschoor, Carl Brown, Ahmer Karimuddin, Manoj Raval, Terry Phang, Elena Vikis, George Melich, Sunil Patel, Kelly Brennan, Sunil Patel, Antonio Caycedo-Marulanda, Shaila Merchant, Christopher Booth, Weidong Kong, Chad McClintock, Clare Bankhead, Carl Heneghan, Kelly Brennan, Sunil Patel, Chad McClintock, Shaila Merchant, Antonio Caycedo-Marulanda, Christopher Booth, Clare Bankhead, Carl Heneghan, Kelly Brennan, Lisa Zhang, Jennifer Flemming, Maya Djerboua, Sulaiman Nanji, Antonio Caycedo-Marulanda, Shaila Merchant, Sunil Patel, Richard Garfinkle, Marie Demian, Sarah Sabboobeh, Jeongyoon Moon, Michael Hulme-Moir, A Sender Liberman, Stan Feinberg, Dana M Hayden, Sami A Chadi, Sebastian Demyttenaere, Louise Samuel, Nevart Hotakorzian, Laurence Quintin, Nancy Morin, Gabriela Ghitulescu, Julio Faria, Carol-Ann Vasilevsky, Marylise Boutros, Sahil Sharma, Tyler Mckechnie, Jigish Khamar, Simarpreet Ichhpuniani, Cagla Eskicioglu, Sydney Candy, Sunil Patel, Shaila Merchant, Antonio Caycedo-Marulanda, Clare Bankhead, Carl Heneghan, Tyler McKechnie, Shaylan Govind, Jay Lee, Yung Lee, Dennis Hong, Cagla Eskicioglu, Tyler McKechnie, Justin Lu, Jigish Khamar, Yung Lee, Nalin Amin, Dennis Hong, Cagla Eskicioglu, Tyler McKechnie, Luisa Cardenas, Daniel Schep, Aristithes Doumouras, Dennis Hong, Raimond Wong, Oren Levine, Cagla Eskicioglu, Lawrence Lee, Carmen Mueller, Barry Stein, Patrick Charlebois, Sender Liberman, Gerald Fried, Liane Feldman, Stephan Robitaille, Anna Wang, Sender Liberman, Patrick Charlebois, Barry Stein, Julio F Fiore, Liane Feldman, Lawrence Lee, Stephan Robitaille, Anna Wang, Sender Liberman, Patrick Charlebois, Barry Stein, Julio F Fiore, Liane Feldman, Lawrence Lee, Hamid Sadri, Alan Barkun, Sydney Selznick, Jordan Levy, Ruxandra Bogdan, Jeffrey Hawel, Ahmad Elnahas, Nawar A Alkhamesi, Christopher M Schlachta, Vanessa Wiseman, Antonio Caycedo-Marulanda, Natasha Iaboni, David Hurlbut, Martin Kaufmann, Kevin Yi Mi Ren, Amoon Jamzad, Parvin Mousavi, Gabor Fichtinger, Christopher J B Nicol, John F Rudan, Vanessa Wiseman, Kelly Brennan, Antonio Caycedo-Marulanda, Shaila Merchant, Chad McClintock, Sunil V Patel, Vanessa Wiseman, Chad McClintock, Clare Bankhead, Shaila Merchant, Antonio Caycedo-Marulanda, Chris Booth, Carl Heneghan, Kelly Brennan, Lisa Zhang, Bright Huo, Alexandra Donaldson, Jennifer Flemming, Sulaiman Nanji, Antonio Caycedo-Marulanda, Shaila Merchant, Susan Brogly, Sunil Patel, Laura Baker, Tori Lenet, Lily Park, Sanjay Murthy, Reilly Musselman, Simarpreet Ichhpuniani, Tyler McKechnie, Jay Lee, Jeremy Biro, Yung Lee, Lily Park, Aristithes Doumouras, Dennis Hong, Cagla Eskicioglu, Garrett Johnson, Harminder Singh, Ramzi Helewa, Kristin Reynolds, Kathryn Sibley, Malcolm Doupe, Lisa Zhang, Kelly Brennan, Jennifer Flemming, Sulaiman Nanji, Shaila Merchant, Maya Djerboua, Antonio Caycedo-Marulanda, Sunil Patel, James Holden, Garrett Johnson, David Hochman, Ramzi Helewa, Jeongyoon Jenny Moon, Richard Garfinkle, Sophie Dell'Aniello, Phyllis Zelkowitz, Carol-Ann Vasilevsky, Paul Brassard, Marylise Boutros, Jeongyoon Jenny Moon, Amine Zoughlami, Wusiman Abibula, Alex Amar, Gabriela Ghitulescu, Carol-Ann Vasilevsky, Paul Brassard, Marylise Boutros, Jeongyoon Jenny Moon, Théa Araji, Allison Pang, Carol-Ann Vasilevsky, Marylise Boutros, Jeongyoon Jenny Moon, Alexa Ehlebracht, Julio Faria, Gabriela Ghitulescu, Nancy Morin, Allison Pang, Carol-Ann Vasilevsky, Marylise Boutros, Tiffany Paradis, Stephan Robitaille, Mahalia Oliver, Patrick Charlebois, Barry Stein, Sender Liberman, Liane S Feldman, Lawrence Lee, Zubair Bayat, Erin Kennedy, Charles Victor, Anand Govindarajan, Sunil Patel, Lisa Zhang, Kelly Brennan, Maya Djerboua, Sulaiman Nanji, Shaila J Merchant, Antonio Caycedo-Marulanda, Jennifer Flemming, Michael Fares Maalouf, Stephan Robitaille, Ruxandra Penta, Makena Pook, Julio Flavio Fiore, Liane Feldman, Lawrence Lee, Alon Wachtel, Nathalie Wong-Chong, Daniel Marinescu, Sahir Bhatnagar, Nancy Morin, Gabriela Ghitulescu, Carol-Ann Vasilevsky, Julio Faria, Marylise Boutros, Victoria Baronas, Arif Arif, Gale Ladua, Eric Bhang, Carl Brown, Fergal Donellan, Heather Stuart, Jonathan Loree, Vanessa Wiseman, Sunil Patel, Lisa Zhang, Peter Hugh MacDonald, Shaila Merchant, Kathleen Wattie Barnett, Antonio Caycedo-Marulanda, Jessica Lie, Carl Brown, Ahmer Karimuddin, Heather Stuart, Amandeep Ghuman, Terry Phang, Manoj Raval, Hyea Min Yoon, Roy Hajjar, Gabriela Fragoso, Manon Oliero, Annie Calvé, Hervé Vennin Rendos, Emmanuel Gonzalez, Nicholas J B Brereton, Thibault Cuisiniere, Claire Gerkins, Souad Djediai, Borhane Annabi, Khoudia Diop, Bertrand Routy, Patrick Laplante, Jean-François Cailhier, Nassima Taleb, Hefzi Alratrout, François Dagbert, Rasmy Loungnarath, Herawaty Sebajang, Frank Schwenter, Ramses Wassef, Richard Ratelle, Eric Debroux, Carole Richard, Manuela M Santos, Alexa Ehlebracht, Doulia Hamad, Hatim Alsulaim, Olivia Monton, Daniel Marinescu, Allison Pang, Carol-Ann Vasilevsky, Marylise Boutros, Natasha Caminsky, Daniel Marinescu, Mohammed Alqahtani, Allison Pang, Gabriela Ghitulescu, Carol-Ann Vasilevsky, Marylise Boutros, Natasha Caminsky, Daniel Marinescu, Richard Garfinkle, Marylise Boutros, Richard Gilbert, Terry Zwiep, Joshua Greenberg, Tori Lenet, Reilly Musselman, Lara Williams, Isabelle Raiche, Daniel McIsaac, Kednapa Thavorn, Dean Fergusson, Husein Moloo, Geneviève Morin, Janyssa Charbonneau, Xavier Paré, Jonathan Frigault, François Letarte, Rebecca C Auer, Michael Ott, Paul Karanicolas, Muriel Brackstone, Shady Ashmalla, Joel Weaver, Vicky Tagalakis, Marylise Boutros, Peter Stotland, Antonio Caycedo-Marulanda, Husein Moloo, Shiva Jayaraman, Sunil Patel, Gregoire LeGal, Silvana Spadafora, Steven Maclellan, Daniel Trottier, Derek Jonker, Timothy Asmis, Ranjeeta Mallick, Timothy Ramsay, Marc Carrier, Terry Phang, Delaram Shojaei, Ali Motamedi, Anu Ghuman, Ahmer Karimuddin, Manoj Raval, Carl Brown, Delaram Shojaei, Jessica Hopkins, Haili Wang, Don Buie, Jessica Hopkins, Haili Wang, Don Buie, Yosef Levin, Nasra Al Busaidi, Fateme Rajabiyazdi, Marie Demian, Marylise Boutros, Armaghan Alam, Ameer Farooq, Carl Brown, Terry Phang, Amandeep Ghuman, Ahmer Karimuddin, Manoj Raval, Farhad Udwadia, Natasha Caminsky, Daniel Marinescu, Mohammed Alqahtani, Allison Pang, Carol-Ann Vasilevsky, Marylise Boutros, Sarah Mansouri, Sonia Cheng Oviedo, Nathalie McFadden, Philip Lagace, Richard Spence, Greg Hirsch, Katerina Neumann, Philip Lagace, Katerina Neumann, Richard Spence, Charbel El-Kefraoui, Garrett Johnson, Harminder Singh, Ramzi Helewa, Marguerite Mainprize, Ayse Yilbas, Fernando Spencer Netto, Joel Katz, Megan Melland-Smith, Bree Sharma, Usman Khan, Markus Selzner, Kevin Verhoeff, Valentin Mocanu, Jerry Dang, Hillary Wilson, Noah Switzer, Daniel Birch, Shahzeer Karmali, Kevin Verhoeff, Valentin Mocanu, Uzair Jogiat, Hayley Forbes, Noah Switzer, Daniel Birch, Shahzeer Karmali, Khadija Nasser, Kevin Verhoeff, Valentin Mocanu, Janice Kung, Kieran Purich, Noah Switzer, Daniel Birch, Shahzeer Karmali, Olivier Mailloux, Nicolas Tassé, André Tchernof, Mélanie Nadeau, Philip Dawe, Andrew Beckett, Laurent Biertho, Kieran Purich, Andrea Lin, Kevin Verhoeff, Valentin Mocanu, Janice Y Kung, Daniel W Birch, Shahzeer Karmali, Noah J Switzer, Marta Whyte, Melinda Fowler-Woods, Amanda Fowler-Woods, Geraldine Shingoose, Andrew Hatala, Felicia Daeninck, Ashley Vergis, Krista Hardy, Kathleen Clouston, Ting Li, Estifanos Debru, Mirza Shaharyar Ahmad, Warren Sun, Jerry Dang, Noah Switzer, Daniel Birch, Shahzeer Karmali, Christopher De Gara, Warren Sun, Jennifer Halasz, Jerry Dang, Noah Switzer, Aliyah Kanji, Daniel Birch, Renuca Modi, Shahzeer Karmali, Hilalion San Ahn, Jeffrey Gu, Amer Jarrar, Nicole Kolozsvari, Yung Lee, Yasith Samarasinghe, Lucy Chen, Akithma Hapugall, Arshia Javidan, Tyler McKechnie, Aristithes Doumouras, Dennis Hong, Eileen Roach, Simon Laplante, Shannon Stogryn, Azusa Maeda, Timothy Jackson, Allan Okrainec, Alexandra Chow, Daniel Birch, Shahzeer Karmali, Aliyah Kanji, Noah Switzer, Jessica Trac, Michael Balas, Denise Gee, Matthew Hutter, Ozanan Meireles, James Jung, Wenjing He, Ashley Vergis, Krista Hardy, Karim Ramji, Vanessa Boudreau, Dennis Hong, Mehran Anvari, Pouya Iranmanesh, Karen Barlow, Tyler Cookson, Rafik Bolis, Harsha Shanthanna, Jonah Shiroky, Ekaterina Kouzmina, Shaidah Deghan, Boris Zevin, Cypriana Koziak, Zacharie Cloutier, Tyler Cookson, Karen Barlow, Vanessa Boudreau, Mehran Anvari, Intekhab Hossain, Jane Brodie, Erin O'Brien, Katherine Tedman-Aucoin, Diana Lawlor, Raleen Murphy, Laurie Twells, David Pace, James Ellsmere, Bradley Evans, Valentin Mocanu, Terry Zhang, Edward Deehan, Dina Kao, Naomi Hotte, Daniel Birch, Shahzeer Karmali, Kalutota Samarasinghe, Jens Walter, Karen Madsen, Nader Hanna, Erin Williams, Weidong Kong, Adam Fundytus, Christopher Booth, Sunil Patel, Antonio Caycedo-Marulanda, Wiley Chung, Sulaiman Nanji, Shaila Merchant, Matthew Castelo, Bettina Hansen, Lawrence Paszat, Nancy Baxter, Adena Scheer, Makena Pook, Tahereh Najafi Ghezeljeh, Maxime Lapointe-Gagner, Philip Nguyen-Powanda, Hiba Elhaj, Fateme Rajabiyazdi, Lawrence Lee, Liane S Feldman, Julio Fiore, Jesse Zuckerman, Rinku Sutradhar, Barbara Haas, Matthew Guttman, Antoine Eskander, Natalie Coburn, Tyler Chesney, Bourke Tillman, Victoria Zuk, Alyson Mahar, Amy Hsu, Wing Chan, Julie Hallet, Woo Jin Choi, Keegan Guidolin, Filomena Servidio-Italiano, Fayez Quereshy, Gonzalo Sapisochin, Akie Watanabe, Eitan Prisman, Elliot Mitmaker, Ross Walker, Jonn Wu, Anne Nguyen, Sam Wiseman, Bianka Saravana-Bawan, Dennis Hong, Michael Gupta, Jesse Pasternak, David Cyr, Omar Vergara-Fernandez, Amanpreet Brar, James Conner, Richard Kirsch, Mantaj Brar, Erin Kennedy, Anand Govindarajan, Robert Gryfe, Helen MacRae, Zane Cohen, Robin McLeod, Carol Swallow, Muriel Brackstone, Farhad Ghasemi, Victoria Ivankovic, Megan Delisle, Dawn Stacey, Jad Abou-Khalil, Fady Balaa, Kimberly Bertens, Brittney Dingley, Guillaume Martel, Kristen McAlpine, Carolyn Nessim, Shaheer Tadros, Marc Carrier, Rebecca Auer, Ananya Gopika Nair, David Lim, Dhruvin Hirpara, Antoine Eskander, Natalie Coburn, Rinku Sutradhar, Wing Chan, Julie Hallet, Cecily Stockley, Felicia Pickard, Alexander Mathieson, Michael Hogan, Melanie Seal, Deanna Ng, Belkacem Acidi, Wendy Johnston, Dario Callegaro, Savtaj Brar, Rebecca Gladdy, Peter Chung, Charles Catton, Korosh Khalili, Charles Honore, Carol Swallow, Shelly Luu, Ning Fu, Karineh Kazazian, Karina Pacholczyk, Deanna Ng, Jossie Swett-Cosentino, Paul Savage, Yukiko Shibahara, Sangeetha Kalimuthu, Osvaldo Espin-Garcia, James Conner, Jonathan Yeung, Gail Darling, Carol Swallow, Léamarie Meloche-Dumas, Frédéric Mercier, Victoria Barabash, Calvin Law, Natalie Coburn, Simron Singh, Sten Myrehaug, Wing Chan, Julie Hallet, Michael A D'Elia, Rebecca C Auer, Ashley Eom, Narry Muhn, Barbara Heller, Peter Lovrics, Katelynn Tang, Shawn Khan, Deanna Ng, Daniel Koerber, Eisar Al-Sukhni, David Cyr, Karineh Kazazian, Carol Swallow, Erika Schmitz, Sameer Apte, Carolyn Nessim, Ko Ta Chen, Judy Ban, Leo Chen, Elaine McKevitt, Rebecca Warburton, Jin-Si Pao, Carol Dingee, Urve Kuusk, Amy Bazzarelli, Jieun Newman-Bremang, Nicole Look Hong, Anna Gagliardi, Bryanna Nyhof, Kevin Verhoeff, Braulio Marfil-Garza, Gurpal Sandha, David Cooper, Khaled Dajani, David Bigam, Blaire Anderson, Tatsuya Kin, Anna Lam, Doug O'Gorman, Peter Senior, Camillo Ricordi, A M James Shapiro, Nic Jette, Michael Moser, Zuhaib Mir, Henry Lam, Jennifer Flemming, Diederick Jalink, Sulaiman Nanji, Sean Bennett, Christopher Griffiths, Betty Zhang, Kasia Tywonek, Brandon Meyers, Pablo Serrano, Luckshi Rajendran, Tori Lenet, Risa Shorr, Jad Abou-Khalil, Kimberly Bertens, Fady Balaa, Guillaume Martel, Jesse Zuckerman, Shiva Jayaraman, Alice Wei, Alyson Mahar, Yosuf Kaliwal, Guillaume Martel, Natalie Coburn, Julie Hallet, Woo Jin Choi, Phil Williams, Marco Claasen, Tommy Ivanics, Marina Englesakis, Steven Gallinger, Bettina Hansen, Gonzalo Sapisochin, Woo Jin Choi, Tommy Ivanics, Marco Claasen, Steven Gallinger, Bettina Hansen, Gonzalo Sapisochin, Richard Gilbert, Tori Lenet, Jad Abou-Khalil, Fady Balaa, Guillaume Martel, Alexandre Brind'Amour, Kimberly Bertens, Tori Lenet, Fady Balaa, Kimberly Bertens, Guillaume Martel, Jad Abou-Khalil, Nawal Amhis, Yves Collin, Marco Claasen, Tommy Ivanics, Christian Toso, Rene Adam, Jan Ijzermans, Gonzalo Sapisochin, Wojtek Polak, Sarah Mansouri, Maxime Léveillé, Christine Lawson, Yves Collin, Lee-Hwa Tai, Adriana Workewych, Brittany Greene, Shiva Jayaraman, Melanie Tsang, Alex Lee, Ahmed Al-Arnawoot, Luckshi Rajendran, Tyler Lamb, Anastasia Turner, Morgann Reid, Janelle Rekman, Richard Mimeault, Jad Abou-Khalil, Kimberly Bertens, Guillaume Martel, Fady Balaa, Evelyn Waugh, Chris Zhang, Madeline Lemke, Juan Glinka, Ken Leslie, Anton Skaro, Ephraim Tang, Alice Zhu, Brittany Greene, Melanie Tsang, Shiva Jayaraman, Helia Nabavian, Lev Bubis, Shiva Jayaraman, Melanie E Tsang, Jorge Roldan, Olivia Ganescu, Tsafrir Vanounou, Jean-Sébastien Pelletier, Andrew Lagrotteria, Brittany Greene, Melanie Tsang, Shiva Jayaraman, Jorge Roldan, Olivia Ganescu, Jean-Sébastien Pelletier, Tsafrir Vanounou, Luckshi Rajendran, Woo Jin Choi, Hala Muaddi, Tommy Ivanics, Marco P A W Classen, Gonzalo Sapisochin
No abstract text is available yet for this article.
2022: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://read.qxmd.com/read/36412125/effects-of-workload-and-job-stress-on-the-shift-work-disorders-among-nurses-pls-sem-modeling
#29
JOURNAL ARTICLE
Keivan Saedpanah, Mohammad Ghasemi, Hesam Akbari, Amir Adibzadeh, Hamed Akbari
Nurses, as the largest forces in the health system, are always challenged with various work responsibilities such as long working hours, lack of manpower and death of patients. This study aimed at providing a model of the relationship between workload and physical and mental health, sleep disorders, and individual and family problems by the mediation role of job stress. The present study is a cross-sectional study that was conducted on 300 nurses in a specialty and sub-specialty hospital in Tehran. For this reason, various questionnaires including demographic, survey of shift workers (SOS) and job stress questionnaires were used to collect the desired data...
November 21, 2022: European Journal of Translational Myology
https://read.qxmd.com/read/36213003/atypical-molluscum-contagiosum-on-multiple-sclerosis-patients-treated-with-fingolimod-a-case-report
#30
Hamed Cheraghmakani, Seyed Mohammad Baghbanian, Maryam Ghasemi
Molluscum contagiosum (MC) is a skin infection caused by a virus of the DNA poxvirus family that has already been reported by Fingolimod. We report two cases. MC can resist standard therapy and discontinuation of the fingolimod may be the only way to treat it.
October 2022: Clinical Case Reports
https://read.qxmd.com/read/36158134/predicting-the-physician-s-specialty-using-a-medical-prescription-database
#31
JOURNAL ARTICLE
Mahboube Akhlaghi, Hamed Tabesh, Behzad Mahaki, Mohammad-Reza Malekpour, Erfan Ghasemi, Marjan Mansourian
Purpose: The present study is aimed at predicting the physician's specialty based on the most frequent two medications prescribed simultaneously. The results of this study could be utilized in the imputation of the missing data in similar databases. Patients and Methods . The research is done through the KAy-means for MIxed LArge datasets (KAMILA) clustering and random forest (RF) model. The data used in the study were retrieved from outpatients' prescriptions in the second populous province of Iran (Khorasan Razavi) from April 2015 to March 2017...
2022: Computational and Mathematical Methods in Medicine
https://read.qxmd.com/read/36129936/a-machine-learning-approach-to-evaluate-the-state-of-hypertension-care-coverage-from-2016-steps-survey-in-iran
#32
JOURNAL ARTICLE
Hamed Tavolinejad, Shahin Roshani, Negar Rezaei, Erfan Ghasemi, Moein Yoosefi, Nazila Rezaei, Azin Ghamari, Sarvenaz Shahin, Sina Azadnajafabad, Mohammad-Reza Malekpour, Mohammad-Mahdi Rashidi, Farshad Farzadfar
BACKGROUND: The increasing burden of hypertension in low- to middle-income countries necessitates the assessment of care coverage to monitor progress and guide future policies. This study uses an ensemble learning approach to evaluate hypertension care coverage in a nationally representative Iranian survey. METHODS: The data source was the cross-sectional 2016 Iranian STEPwise approach to risk factor surveillance (STEPs). Hypertension was based on blood pressure ≥140/90 mmHg, reported use of anti-hypertensive medications, or a previous hypertension diagnosis...
2022: PloS One
https://read.qxmd.com/read/36056015/sars-cov-2-mrna-vaccine-candidate-corenapcin-%C3%A2-induces-robust-humoral-and-cellular-immunity-in-mice-and-non-human-primates
#33
JOURNAL ARTICLE
Reza Alimohammadi, Meysam Porgoo, Mohamad Eftekhary, Seyed Hossein Kiaie, Ehsan Ansari Dezfouli, Maryam Dehghani, Kaveh Nasrollahi, Talieh Malekshahabi, Maryam Heidari, Sedigheh Pouya, Masoumeh Alimohammadi, Dorsa Sattari Khavas, Mohammad Sadra Modaresi, Mohammad Hossein Ghasemi, Hamed Ramyar, Fatemeh Mohammadipour, Fateme Hamzelouei, Ahmadreza Mofayezi, Seyed Saeed Mottaghi, Amirhosein Rahmati, Mohsen Razzaznian, Vista Tirandazi, Mahdi Tat, Fatemeh Borzouee, Hossein Sadeghi, Melika Haji Mohammadi, Leila Rastegar, Seyed Milad Safar Sajadi, Hossein Ehsanbakhsh, Hamed Bazmbar, Zeinab Baghernejadan, Maedeh Shams Nouraei, Pouya Pazooki, Mina Pahlavanneshan, Khadijeh Alishah, Fateme Nasiri, Neda Mokhberian, Seyedeh Shima Mohammadi, Shima Akar, Hamidreza Niknam, Marzieh Azizi, Mohammad Ajoudanian, Mohammad Hossein Moteallehi-Ardakani, Seyed Ali Mousavi Shaegh, Reihaneh Ramezani, Vahid Salimi, Reza Moazzami, Seyed Mahmoud Hashemi, Somaye Dehghanizadeh, Vahid Khoddami
At the forefront of biopharmaceutical industry, the messenger RNA (mRNA) technology offers a flexible and scalable platform to address the urgent need for world-wide immunization in pandemic situations. This strategic powerful platform has recently been used to immunize millions of people proving both of safety and highest level of clinical efficacy against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here we provide preclinical report of COReNAPCIN® ; a vaccine candidate against SARS-CoV-2 infection...
September 2, 2022: NPJ Vaccines
https://read.qxmd.com/read/36001178/in-silico-and-in-vitro-analysis-of-a-rational-mutation-in-giii-signal-peptide-and-its-effects-on-periplasmic-expression-of-rhgh-in-e-coli
#34
JOURNAL ARTICLE
Fahimeh Ghasemi, Hamed Zare, Alireza Zomorodipour, Maryam Hosseinzade Shirzeyli, Marek Kieliszek
The secretion efficiency of a heterologous protein in E. coli is mainly dictated by the N-terminal signal peptide fused to the desired protein. In this study, we aimed to select and introduce mutations into the - 1, - 2 and - 3 positions of the gIII signal peptide (originated from filamentous phage fd Gene III) fused to the N-terminus of the human growth hormone (hGH), and study its effect on the secretion efficiency of the recombinant hGH into the periplasmic space of E. coli Top10. Bioinformatics software such as SignalP-5...
August 24, 2022: Archives of Microbiology
https://read.qxmd.com/read/35933373/nanobodies-new-molecular-instruments-with-special-specifications-for-targeting-diagnosis-and-treatment-of-triple-negative-breast-cancer
#35
REVIEW
Hamid Bakherad, Fahimeh Ghasemi, Maryam Hosseindokht, Hamed Zare
Breast cancer is the most common type of cancer in women and the second leading cause of cancer death in female. Triple-negative breast cancer has a more aggressive proliferation and a poorer clinical diagnosis than other breast cancers. The most common treatments for TNBC are chemotherapy, surgical removal, and radiation therapy, which impose many side effects and costs on patients. Nanobodies have superior advantages, which makes them attractive for use in therapeutic agents and diagnostic kits. There are numerous techniques suggested by investigators for early detection of breast cancer...
August 6, 2022: Cancer Cell International
https://read.qxmd.com/read/35717144/effective-factors-in-people-s-preventive-behaviors-during-covid-19-pandemic-a-systematic-review-and-meta-synthesis
#36
JOURNAL ARTICLE
Hamed Fattahi, Faeze Ghasemi Seproo, Arash Fattahi
BACKGROUND: The overwhelming outbreak of covid-19 has forced governments all over the world to consider different measures to face this challenging situation. A vitally important element to the declining transmission of viruses is changing behaviors based on reliable information. This study was designed and implemented to identify factors affecting the preventive behaviors during the covid-19 pandemic. METHODS: This thematic synthesis was carried out in order to create a set of central themes that summarize all of the issues raised in the articles reviewed in this study...
June 18, 2022: BMC Public Health
https://read.qxmd.com/read/35616381/the-effect-of-preconditioning-agents-on-cardiotoxicity-and-neurotoxicity-of-carbon-monoxide-poisoning-in-animal-studies-a-systematic-review
#37
JOURNAL ARTICLE
Hamed Baharara, Hanieh Ghasemi, Sara Samadi, Bahar Roohshad, Vahid Jomehzadeh, Khosrow Ravankhah Moghaddam, Amir Hooshang Mohammadpour, Omid Arasteh
BACKGROUND: Carbon monoxide (CO) poisoning is a common intoxication and many people die yearly due to CO poisoning and preconditioning agents attenuate brain and cardiac injury caused by intoxication. It is critical to fully understand the efficacy of new methods to directly target the toxic effect of CO, such as conditioning agents, which are currently under development. This study aims to systematically investigate current evidence from animal experiments and the effects of administration preconditions in acute and late phases after CO poisoning on cardiotoxicity and neurotoxicity...
May 26, 2022: Drug and Chemical Toxicology
https://read.qxmd.com/read/35612701/cigarette-butts-as-a-super-challenge-in-solid-waste-management-a-review-of-current-knowledge
#38
REVIEW
Afsaneh Ghasemi, Mohammad Mehdi Golbini Mofrad, Iman Parseh, Ghassem Hassani, Hamed Mohammadi, Ramin Hayati, Navid Alinejad
Filtered cigarette is the most common type of tobacco used and cigarette butt is the most important environmental consequence of smoking. This study aimed to investigate the cigarette butt management and identify future needs to improve the current situation. The results showed that cigarette butts are the most abundant and widespread hazardous waste in the world. The current form of cigarette butt management has inferior performance that faced waste management systems with serious challenges. The results showed that reducing the littering rate and recycling are known as basic strategies in the management of this hazardous waste...
May 25, 2022: Environmental Science and Pollution Research International
https://read.qxmd.com/read/35598001/simultaneous-retrograde-venous-and-anterograde-arterial-bullet-embolism-a-case-report
#39
JOURNAL ARTICLE
Ahmad Hosseinzadeh, Mohammad Moeini Farsani, Mohamad Mahdi Mahmoudi, Ahmadreza Hekmatnia, Meghdad Ghasemi Gorji, Majid Asnaashari, Hamed Ghoddusi Johari, Reza Shahriarirad
BACKGROUND: Bullet embolus is a rare condition following gunshot injuries and represents a clinical challenge regarding both diagnosis and management. CASE PRESENTATION: We report the case of a 35-year-old Iranian (Middle-Eastern) male patient with a shotgun injury to both buttocks, which traveled to the heart and the popliteal area through the femoral vein and superficial femoral artery, respectively. Surgical intervention was applied for the popliteal pellet, and the patient was discharged without further complications...
May 22, 2022: Journal of Medical Case Reports
https://read.qxmd.com/read/35396297/safety-and-immunogenicity-of-an-inactivated-virus-particle-vaccine-for-sars-cov-2-biv1-coviran-findings-from-double-blind-randomised-placebo-controlled-phase-i-and-ii-clinical-trials-among-healthy-adults
#40
JOURNAL ARTICLE
Minoo Mohraz, Mohammadreza Salehi, Payam Tabarsi, Mohsen Abbasi-Kangevari, Seyyed-Hadi Ghamari, Erfan Ghasemi, Maryam Amini Pouya, Negar Rezaei, Naser Ahmadi, Kazem Heidari, Mohammad-Reza Malekpour, Mojtaba Nasiri, Ali Akbar Amirzargar, Sahar Saeedi Moghaddam, Bagher Larijani, Hamed Hosseini
OBJECTIVE: Assessing safety and immunogenicity of an inactivated whole virus particle vaccine. DESIGN: Single-centre, double-blind, randomised, placebo-controlled, phase I (stage I: 18-50, stage II: 51-75 years), phase II (18-75 years) clinical trials. SETTING: 29 December 2020 to 22 April 2021. PARTICIPANTS: Stage I-phase I: 56 participants; stage II-phase I: 32; phase II: 280. INTERVENTION: During stage I, participants randomly (3:3:1) received 3 µg, 5 µg vaccine or placebo in a 14-day interval...
April 8, 2022: BMJ Open
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