Emmanuel Novy, Jérémie Rivière, Maxime Nguyen, Gaëlle Arfeuille, Guillaume Louis, Bélaïd Bouhemad, Julien Pottecher, Stéphane Hecketsweiler, Adeline Germain, François-Xavier Laithier, Marie-Reine Losser, Anne Debourgogne, Yohann Bernard, Hélène Rousseau, Cédric Baumann, Amandine Luc, Julien Birckener, Marie-Claire Machouart, Philippe Guerci
BACKGROUND: Intra-abdominal candidiasis (IAC) is difficult to predict in critically ill patients with intra-abdominal infection, leading to the overuse of antifungal treatments. Serum and peritoneal 1.3-beta-D-glucan (sBDG and pBDG) have been proposed to confirm or invalidate the diagnosis of IAC, but clinical studies have reported inconsistent results, notably because of heterogeneous populations with a low IAC prevalence. This study aimed to identify a high-risk IAC population and evaluate pBDG and sBDG in diagnosing IAC...
November 30, 2023: Critical Care: the Official Journal of the Critical Care Forum