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JOURNAL ARTICLE
Olivia Tausendfreund, Martin Bidlingmaier, Sebastian Martini, Hannah Reif, Michaela Rippl, Katharina Schilbach, Ralf Schmidmaier, Michael Drey
PURPOSE: It is unclear whether the age-related decline in the somatotropic axis stems from a reduced growth hormone (GH) production in the pituitary gland, or from a peripheral origin akin to an acquired GH resistance. With the help of a GHRH/arginine test, high-aged multimorbid hospitalized patients with IGF-I deficiency are to be tested to determine whether there is primarily a pituitary GH deficiency in the sense of a somatopause. METHODS: Seventeen multimorbid patients (eleven men and six women) with a mean age of 82 years, with IGF-I concentrations below two standard deviations of 30-year-old men and women were identified...
May 31, 2024: Pituitary
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JOURNAL ARTICLE
Benjamin J Solomon, Geoffrey Liu, Enriqueta Felip, Tony S K Mok, Ross A Soo, Julien Mazieres, Alice T Shaw, Filippo de Marinis, Yasushi Goto, Yi-Long Wu, Dong-Wan Kim, Jean-François Martini, Rossella Messina, Jolanda Paolini, Anna Polli, Despina Thomaidou, Francesca Toffalorio, Todd M Bauer
PURPOSE: Lorlatinib improved progression-free survival (PFS) and intracranial activity versus crizotinib in patients with previously untreated, advanced, ALK -positive non-small cell lung cancer (NSCLC) in the phase III CROWN study. Here, we report long-term outcomes from CROWN after 5 years of follow-up. METHODS: Two hundred ninety-six patients with ALK -positive NSCLC were randomly assigned 1:1 to receive lorlatinib 100 mg once daily (n = 149) or crizotinib 250 mg twice daily (n = 147)...
May 31, 2024: Journal of Clinical Oncology
#3
JOURNAL ARTICLE
H Ağırcan, D Convertino, A Rossi, L Martini, S Pace, N Mishra, K Küster, U Starke, G Kartal Şireli, C Coletti, S Forti
Single-layer tungsten disulfide (WS2 ) is among the most widely investigated two-dimensional materials. Synthesizing it over large areas would enable the exploitation of its appealing optical and electronic properties in industrial applications. However, defects of different nature, concentration and distribution profoundly affect the optical as well as the electronic properties of this crystal. Controlling the defect density distribution can be an effective way to tailor the local dielectric environment and therefore the electronic properties of the system...
May 29, 2024: Nanoscale advances
#4
JOURNAL ARTICLE
Dieke Martini, Hugo Schalkwijk, Lisette Schoonhoven, Mirko Noordegraaf, Pieterbas Lalleman
OBJECTIVE: This study aims to better understand how new future-oriented nursing roles are enacted in a general hospital. DESIGN: A learning history, that is, a participatory action-oriented research design to explore and foster organizational learning. METHODS: Data collection consisted of a (historical) document analysis, the shadowing of differentiated nursing practices (36 h), 22 open interviews, 4 oral history interviews, 2 focus groups and a podcast series (7 h) created with participants...
May 29, 2024: Journal of Advanced Nursing
#5
JOURNAL ARTICLE
Alex Buoite Stella, Katia Rupel, Martina Tamos, Giampaolo Fratter, Manuela Deodato, Miriam Martini, Matteo Biasotto, Roberto Di Lenarda, Giulia Ottaviani
OBJECTIVES: Few studies used thermal quantitative sensory testing to assess the effects of repeated capsaicin gel administration in the oral cavity. This study aimed to investigate thermal sensory and pain thresholds before and after repeated capsaicin gel administration. SUBJECTS AND METHODS: Ten healthy females (22 ± 2 years) applied a capsaicin gel on the gingival mucosa twice daily for 14 days, and heat pain threshold, warm detection threshold, cold pain threshold, and cold detection threshold were assessed on the oral mucosa...
May 29, 2024: Oral Diseases
#6
JOURNAL ARTICLE
Manuela Deodato, Antonio Granato, Alex Buoite Stella, Miriam Martini, Enrico Marchetti, Ilaria Lise, Alessandra Galmonte, Luigi Murena, Paolo Manganotti
The main aim of this study was to investigate the efficacy of a dual task protocol in people with episodic migraine with respect to both active exercises only and cognitive task only treatments, concerning some neurophysiological and clinical outcomes. A randomized control trial was adopted in people with episodic migraine without aura. Some neurophysiological and clinical outcomes were collected (t0): resting motor threshold (rMT), short intracortical inhibition (SICI) and facilitation (ICF), pressure pain threshold (PPT), trail making test (TMT), frontal assessment battery (FAB), headache-related disability (MIDAS) and headache parameters...
May 29, 2024: Neurological Sciences
#7
JOURNAL ARTICLE
Alessio Gabbani, Elisa Della Latta, Ananthakrishnan Mohan, Andrea Scarperi, Xiaoyan Li, Marina Ruggeri, Francesca Martini, Francesco Biccari, Mathieu Kociak, Marco Geppi, Silvia Borsacchi, Francesco Pineider
We develop here a comprehensive experimental approach to independently determine charge carrier parameters, namely, carrier density and mass, in plasmonic indium tin oxide nanocrystals. Typically, in plasmonic nanocrystals, only the ratio between these two parameters is accessible through optical absorption experiments. The multitechnique methodology proposed here combines single particle and ensemble optical and magneto-optical spectroscopies, also using 119 Sn solid-state nuclear magnetic resonance spectroscopy to probe the surface depletion layer...
May 28, 2024: ACS Nano
#8
JOURNAL ARTICLE
Elizabete A Dos Santos, Lígia Araújo Martini Cavalheiro, Daniela Rodrigues, Aristides Machado-Rodrigues, Maria-Raquel Silva, Helena Nogueira, Cristina Padez
OBJECTIVES: To investigate the association among sun exposure time, vitamin D intake, dietary patterns, and socioeconomic status in Portuguese children. METHODS: Participants aged 3-11 years (50.1% females) were recruited from public and private schools (n = 118) in the districts of Coimbra (n = 2980), Lisbon (n = 3066), and Porto (n = 2426). Parents reported their children's daily sun exposure time during the summer season and reported children's food consumption, including vitamin D food sources, using standardized questionnaires...
May 28, 2024: American Journal of Human Biology: the Official Journal of the Human Biology Council
#9
JOURNAL ARTICLE
Tri Martiana, Firman Suryadi Rahman, Santi Martini, Indriati Paskarini, Soenarnatalina Melaniani, Ajeng Kusumawardani, Juliana Jalaludin, Khadizah H Abd Mumin
CONTEXT: As female workers face a higher risk of exposure to workplace hazards than women in general, it is imperative that measures be put in place in the workplace to ensure safe and healthy pregnancies. OBJECTIVES: This study aimed to analyze the effects of occupational hazards in the workplace environment on the potential for pregnancy disorders experienced by female workers. METHODS: This was an analytical, observational study with a case-control design...
May 30, 2024: Heliyon
#10
JOURNAL ARTICLE
Gagandeep Kaur, Lukasz L Stelinski, Xavier Martini, Nathan Boyd, Rachel Mallinger, Sriyanka Lahiri
Given the recent invasion of Scirtothrips dorsalis Hood in North America, there is limited information regarding their distribution and population dynamics in cultivated small fruit crops. Therefore, we investigated the spatial and temporal distribution of S. dorsalis and their natural enemies in commercially produced strawberry fields in Florida. During 2 consecutive strawberry production seasons, 4 and 6 geographically separated strawberry fields were sampled and were divided into grids with 30-40 sampling points per field...
May 27, 2024: Journal of Economic Entomology
#11
JOURNAL ARTICLE
Wayne A Martini, Clinton E Jokerst, Nicole Hodsgon, Andrej Urumov
INTRODUCTION: During the coronavirus 2019 pandemic, hospitals in the United States experienced a shortage of contrast agent, much of which is manufactured in China. As a result, there was a significantly decreased amount of intravenous (IV) contrast available. We sought to determine the effect of restricting the use of IV contrast on emergency department (ED) length of stay (LOS). METHODS: We conducted a single-institution, retrospective cohort study on adult patients presenting with abdominal pain to the ED from March 7-July 5, 2022...
May 2024: Western Journal of Emergency Medicine
#12
EDITORIAL
Kenneth Timmis, John E Hallsworth, Terry J McGenity, Rachel Armstrong, María Francisca Colom, Zeynep Ceren Karahan, Max Chavarría, Patricia Bernal, Eric S Boyd, Juan Luis Ramos, Martin Kaltenpoth, Carla Pruzzo, Gerard Clarke, Purificación López-Garcia, Michail M Yakimov, Jessamyn Perlmutter, Chris Greening, Emiley Eloe-Fadrosh, Willy Verstraete, Olga C Nunes, Oleg Kotsyurbenko, Pablo Iván Nikel, Paola Scavone, Max M Häggblom, Rob Lavigne, Frédérique Le Roux, James K Timmis, Victor Parro, Carmen Michán, José Luis García, Arturo Casadevall, Shelley M Payne, Joachim Frey, Omry Koren, James I Prosser, Leo Lahti, Rup Lal, Shailly Anand, Utkarsh Sood, Pierre Offre, Casey C Bryce, Allen Y Mswaka, Jörg Jores, Betül Kaçar, Lars Mathias Blank, Nicole Maaßen, Phillip B Pope, Horia L Banciu, Judith Armitage, Sang Yup Lee, Fengping Wang, Thulani P Makhalanyane, Jack A Gilbert, Thomas K Wood, Branka Vasiljevic, Mario Soberón, Zulema Udaondo, Fernando Rojo, Jyoti Prakash Tamang, Tatiana Giraud, Jeanne Ropars, Thaddeus Ezeji, Volker Müller, Hirofume Danbara, Beate Averhoff, Angela Sessitsch, Laila Pamela Partida-Martínez, Wei Huang, Søren Molin, Pilar Junier, Ricardo Amils, Xiao-Lei Wu, Eliora Ron, Huseyin Erten, Elaine Cristina Pereira de Martinis, Alexander Rapoport, Maarja Öpik, W Donald R Pokatong, Courtney Stairs, Mohammad Ali Amoozegar, Jéssica Gil Serna
EXECUTIVE SUMMARY: Microbes are all pervasive in their distribution and influence on the functioning and well-being of humans, life in general and the planet. Microbially-based technologies contribute hugely to the supply of important goods and services we depend upon, such as the provision of food, medicines and clean water. They also offer mechanisms and strategies to mitigate and solve a wide range of problems and crises facing humanity at all levels, including those encapsulated in the sustainable development goals (SDGs) formulated by the United Nations...
May 2024: Microbial Biotechnology
#13
Charlotte Michel, Fedoua Echahidi, Sammy Place, Lorenzo Filippin, Vincent Colombie, Nicolas Yin, Delphine Martiny, Olivier Vandenberg, Denis Piérard, Marie Hallin
Legionella pneumophila can cause a large panel of symptoms besides the classic pneumonia presentation. Here we present a case of fatal nosocomial cellulitis in an immunocompromised patient followed, a year later, by a second case of Legionnaires' disease in the same ward. While the first case was easily assumed as nosocomial based on the date of symptom onset, the second case required clear typing results to be assigned either as nosocomial and related to the same environmental source as the first case, or community acquired...
April 25, 2024: Microorganisms
#14
JOURNAL ARTICLE
Federica Salari, Cristina Roncoroni, Francesco Mariottini, Alessandra Muzic, Iolanda Altomonte, Irene Sodi, Susy Creatini, Lorella Giuliotti, Giovanni Brajon, Mina Martini
The objective of the present work was to categorize the risks in the on-farm welfare of dairy sheep in semi-extensive systems in order to highlight if risks in welfare vary according to the farm size. To the best of our knowledge, this study constitutes one of the few categorizations of the risks in the welfare of dairy sheep reared semi-extensively. The survey was conducted on 12 semi-extensive dairy sheep farms in Tuscany (Central Italy), which were classified according to flock size: <500, from 500 to 1000, and >1000...
May 7, 2024: Animals: An Open Access Journal From MDPI
#15
JOURNAL ARTICLE
Alzbeta Chabronova, Qiurong Ding, Miriam Martini, Pramod C Nair
No abstract text is available yet for this article.
May 23, 2024: Trends in Molecular Medicine
#16
JOURNAL ARTICLE
V Martini, P Moretti, F Sini, A Ubiali, A Poggi, F Riondato
T-zone-like cells of undetermined significance (TZUS) share the same phenotypic pattern (CD45-CD5+) with T-zone lymphoma cells and were first described a few years ago in the peripheral blood (PB) of healthy aged American Golden retrievers (GR). History of bladder and eye disease increased the odd of circulating TZUS in the American GR population. Since differences among dogs may exist according to the geographical region of origin, herein we screened 489 PB samples to assess potential factors predisposing to the presence of circulating TZUS in dogs living in Italy...
May 22, 2024: Veterinary Journal
#17
REVIEW
Anna Fornasari, Salomé Kuntz, Chiara Martini, Paolo Perini, Elisa Cabrini, Antonio Freyrie, Anne Lejay, Nabil Chakfé
Vascular calcifications in aorto-iliac arteries are emerging as crucial risk factors for cardiovascular diseases (CVDs) with profound clinical implications. This systematic review, following PRISMA guidelines, investigated methodologies for measuring these calcifications and explored their correlation with CVDs and clinical outcomes. Out of 698 publications, 11 studies met the inclusion criteria. In total, 7 studies utilized manual methods, while 4 studies utilized automated technologies, including artificial intelligence and deep learning for image analyses...
May 19, 2024: Diagnostics
#18
JOURNAL ARTICLE
Marco Nicolò, Altin Adraman, Camilla Risoli, Anna Menta, Francesco Renda, Michele Tadiello, Sara Palmieri, Marco Lechiara, Davide Colombi, Luigi Grazioli, Matteo Pio Natale, Matteo Scardino, Andrea Demeco, Ruben Foresti, Attilio Montanari, Luca Barbato, Mirko Santarelli, Chiara Martini
(1) Background: Computed tomography (CT) plays a paramount role in the characterization and follow-up of COVID-19. Several score systems have been implemented to properly assess the lung parenchyma involved in patients suffering from SARS-CoV-2 infection, such as the visual quantitative assessment score (VQAS) and software-based quantitative assessment score (SBQAS) to help in managing patients with SARS-CoV-2 infection. This study aims to investigate and compare the diagnostic accuracy of the VQAS and SBQAS with two different types of software based on artificial intelligence (AI) in patients affected by SARS-CoV-2...
May 8, 2024: Diagnostics
#19
JOURNAL ARTICLE
Jabril R Johnson, Rachel N Martini, Yate-Ching Yuan, Leanne Woods-Burnham, Mya Walker, Greisha L Ortiz-Hernandez, Firas Kobeissy, Dorothy Galloway, Amani Gaddy, Chidinma Oguejiofor, Blake Allen, Deyana Lewis, Melissa B Davis, K Sean Kimbro, Clayton C Yates, Adam B Murphy, Rick A Kittles
Vitamin D3 is a steroid hormone that confers anti-tumorigenic properties in prostate cells. Serum vitamin D3 deficiency has been associated with advanced prostate cancer (PCa), particularly affecting African American (AA) men. Therefore, elucidating the pleiotropic effects of vitamin D on signaling pathways, essential to maintaining non-malignancy, may provide additional drug targets to mitigate disparate outcomes for men with PCa, especially AA men. We conducted RNA sequencing on an AA non-malignant prostate cell line, RC-77N/E, comparing untreated cells to those treated with 10 nM of vitamin D3 metabolite, 1α,25(OH)2 D3 , at 24 h...
May 15, 2024: Biology
#20
JOURNAL ARTICLE
V Rabbogliatti, F A Brioschi, A Pecile, V Bronzo, V Martini, P Dall'Ara, G Ravasio, D Groppetti
General anesthesia and surgical stress can suppress the immunological response by acting both directly on the immune system and indirectly on the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. Disturbance of the immune system during the perioperative period can lead to complications such as wound-healing disorders and infections up to sepsis. Effectiveness of acupuncture in regulating the immune function by increasing leukocyte numbers and inhibiting inflammatory response has been proven...
May 21, 2024: Veterinary Journal
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