Nisha Sahoo, Nitin Dhochak, Kana R Jat, Jhuma Sankar, Rakesh Lodha, Gomathy Sethuraman, Madhulika Kabra, Sushil K Kabra
OBJECTIVE: To develop a diagnostic algorithm for cystic fibrosis (CF) in the setting of unavailability of sweat chloride, based on clinical features and basic laboratory investigations. METHODS: In a prospective observational study, we enrolled children with recurrent/persistent pneumonia with either malabsorption or poor growth, undergoing a sweat chloride test, between January 2019 and December 2020. They were simultaneously evaluated for aquagenic wrinkling of hands, stool fat globules, sputum for bacterial culture, blood gas, and serum electrolytes...
September 5, 2022: Pediatric Pulmonology