Lisa A Harvey, Joanne V Glinsky, Jackie Chu
STUDY DESIGN: Systematic review. OBJECTIVE: To determine whether any physiotherapy interventions increase Spinal Cord Independence Measure or Functional Independence Measure scores (SCIM/FIM) in people with spinal cord injury (SCI), with the overall aim of determining whether any physiotherapy interventions need to be controlled for in studies examining the effects of novel experimental interventions on SCIM/FIM. METHODS: A systematic review was conducted to identify all randomised controlled trials examining the effect of any physiotherapy intervention on SCIM/FIM in people with SCI...
June 7, 2021: Spinal Cord
Mohammad Ashouri, Kasra Karvandian, Zahra Ataie-Ashtiani, Narjes Mohammadzadeh
INTRODUCTION: Utilising epidural analgesia (EA) during major abdominal surgery in combination with general anaesthetic, is a proven approach to decrease anaesthetic requirement in patients with severe comorbidities, enhance recovery and improve pain management. CASE PRESENTATION: Herein we report a case of an 81-years-old female with bilateral lower limb sensory loss, saddle paraesthesia, paraplegia, and incontinence following a thoracic epidural catheterisation required for low anterior resection of rectal adenocarcinoma...
May 26, 2021: International Journal of Surgery Case Reports
Sentiljana Gumeni, Chiara Vantaggiato, Monica Montopoli, Genny Orso
Hereditary spastic paraplegia (HSP) is a group of inherited neurodegenerative conditions that share a characteristic feature of degeneration of the longest axons within the corticospinal tract, which leads to progressive spasticity and weakness of the lower limbs. Mutations of over 70 genes produce defects in various biological pathways: axonal transport, lipid metabolism, endoplasmic reticulum (ER) shaping, mitochondrial function, and endosomal trafficking. HSPs suffer from an adequate therapeutic plan. Currently the treatments foreseen for patients affected by this pathology are physiotherapy, to maintain the outgoing tone, and muscle relaxant therapies for spasticity...
2021: Frontiers in Neuroscience
Teik Chiang Goh, Mohd Yazid Bajuri, Mohamad Fauzlie Yusof, Husna Mohd Apandi, Faris Aiman Sarifulnizam
We report the case of a 14-year-old girl who presented with a one-month history of back pain and bilateral lower limb weakness preceded by constitutional symptoms. She neither had a family history of malignancy nor a previous history of trauma. A series of imaging procedures revealed an aggressive lesion of the T12 vertebra with a large soft-tissue component and intraspinal extension leading to spinal cord compression causing cord edema. She underwent urgent posterior instrumentation and fixation of T9 to T12 vertebrae due to worsening neurological deficits...
March 3, 2021: Curēus
Paulo Henrique Ferreira de Araujo Barbosa, Joanne V Glinsky, Emerson Fachin-Martins, Lisa A Harvey
STUDY DESIGN: Systematic review. OBJECTIVE: To determine the effectiveness of physiotherapy interventions for the treatment of spasticity in people with spinal cord injuries. SETTING: Not applicable. METHODS: A comprehensive search was undertaken to identify all randomised controlled trials of physiotherapy interventions that included an assessor-reported (objective) or participant-reported (subjective) measure of spasticity...
February 9, 2021: Spinal Cord
Yuan-Yuan Lin, Yang Sun, Yu Jiang, Bao-Zhi Song, Li-Juan Ke
BACKGROUND: Although choriocarcinoma is thought to be a malignancy curable by chemotherapy, there remain difficult and challenging problems in cases with high prognostic scores or extensive metastases, for which the treatment is limited. Particularly, chemotherapy in combination with other treatments offers promising therapeutic potential for these cases. CASE SUMMARY: We present the case of a 40-year-old female patient who suffered from life-threatening hemoptysis and paraplegia due to choriocarcinoma with pulmonary, hepatic and spinal metastases...
September 6, 2020: World Journal of Clinical Cases
Nalina Gupta
STUDY DESIGN: Qualitative study. OBJECTIVES: To formulate recommendations for standards of physiotherapy care for people with complete traumatic paraplegia in India using a Delphi methodology. SETTING: India. METHODS: Twenty-three physiotherapy experts were invited to participate in an online consensus process. Fourteen (n = 14) of 23 physiotherapy experts from India accepted an invitation to participate in an online consensus development exercise (Response rate-60...
March 11, 2020: Spinal Cord Series and Cases
Gabriella Paparella, Marinela Vavla, Lisa Bernardi, Giulia Girardi, Cristina Stefan, Andrea Martinuzzi
Introduction: The Hereditary Spastic Paraplegia (HSP) is a heterogeneous group of neurodegenerative disorders characterized by progressive spasticity and lower limbs (LL) weakness. There is no treatment to cure or halt the disease, except for symptomatic therapy. The use of botulinum toxin type A (BoNT-A) is one of the primary treatment for focal spasticity. Physiotherapy (PT) can help in maintaining residual functioning. We performed a retrospective study to evaluate the effect of the combined BoNT-A and intensive PT in patients with HSP...
2020: Frontiers in Neuroscience
Stephen F Figoni, David R Dolbow, Edwin C Crawford, Margaret L White, Sambit Pattanaik
Context: This review synthesizes the findings of previous research studies on the cardiovascular and metabolic benefits of aerobic exercise for individuals with tetraplegia secondary to spinal cord injury. They are often less active due to muscular paralysis, sensory loss, and sympathetic nervous system dysfunction that result from injury. Consequently, these persons are at higher risk for exercise intolerance and secondary health conditions. Objective: To evaluate the evidence concerning efficacy of aerobic exercise training for improving health and exercise performance in persons with tetraplegia from cervical injury...
February 11, 2020: Journal of Spinal Cord Medicine
Érika Branco, José G R Alves, Luane L Pinheiro, Leandro N Coutinho, Carolina R M Gomes, Gilvando R Galvão, Glaucia R de Oliveira Dos Santos, Luiz F M Moreira, Maridelzira B M David, Danielle M Martins, Edivaldo H C de Oliveira, Michel P C de Souza, Patrícia C B Beltrão-Braga, Fabiele B Russo, Graciela C Pignatari, Carla M F de Carvalho Miranda, Ana R de Lima
Central nervous system (CNS) trauma is often related to tissue loss, leading to partial or complete disruption of spinal cord function due to neuronal death. Although generally irreversible, traditional therapeutic efforts, such as physical therapy exercises, are generally recommended, but with a poor or reduced improvement of the microenvironment, which in turn stimulates neuroplasticity and neuroregeneration. Mesenchymal stem cells (MSCs) have paracrine, immunomodulatory, and anti-inflammatory effects. Here we use stem cells to see if they can promote not only physical but also the functional regeneration of neuronal tissue in dogs with CNS traumas...
September 14, 2019: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
Mahesh Kamate, Mayank Detroja
Introduction: Hereditary spastic paraplegia (HSP) is a group of neurogenetic disorders seen mainly in adults. With the advancement in genetics, more than 78 types of HSP have been identified, with increasing identification of HSP in children. However, there is scant literature on this from India. Materials and Methods: Retrospective chart review of patients with HSP diagnosed in the last 6 years was done. The data were extracted and analyzed. Results: A total of 11 patients had a diagnosis of HSP (genetically confirmed), with mean age of presentation at 21...
July 2019: Annals of Indian Academy of Neurology
Mohammadreza Emamhadi, Shervin Ghadarjani, Babak Alijani, Shahrokh Yousefzadeh-Chabok, Hamid Behzadnia, Amin Naseri, Sasan Andalib
Spontaneous cervical epidural hematoma (SCEH), which is a rare disease, is manifested as by a sudden quadriplegia or paraplegia and other neurological deficits. SCEH can compress the spinal cord resulting in its clinical manifestations. The reported etiological risk factors are anticoagulants, coagulopathies, vascular malformations, infections, and herniated discs. Here, we report a 77-year-old woman with a presenting chief complaint of left hemiparesis and a history of hypertension. The medical drugs in use were aspirin and antihypertensives...
January 2019: Asian Journal of Neurosurgery
Aghigh Haidari, Feridoun Sabzi, Samsam Dabiri
Paraplegia is an exceedingly rare neurologic complication after off-pump coronary artery bypass graft (OPCAB) surgery commonly caused by spinal cord ischemia (SCI). SCI is not a well unknown clinical phenomenon in the postoperative course. SCI has been reported after noncardiac surgery in otherwise healthy subjects in whom only one risks factor i.e. severe hypotension has been documented. SCI has also been reported as a rare complication among the other neurologic sequels of cardiac surgery. We report a case of paraplegia in a patient with metabolic syndrome and multiples risk factors after an OPCAB...
December 2017: Acta Medica Iranica
Aiman K Al-Wahaibi, Santosh Kumar, Ali Al-Risi, Farook Wali
Acute polyneuropathy is a rare manifestation of severe hyperthyroidism. We report a 22-year-old Omani male who presented to the Sohar Hospital, Sohar, Oman, in 2016 with acute-onset rapidly progressive flaccid areflexic paraplegia as the presenting manifestation of thyrotoxicosis. Nerve conduction studies revealed mixed axonal and demyelinating polyneuropathy in both the motor and sensory nerves. Treatment of the hyperthyroidism with β-blockers and carbimazole along with physiotherapy resulted in the patient's full recovery and the alleviation of his symptoms...
November 2017: Sultan Qaboos University Medical Journal
Nalina Gupta, Kavitha Raja
STUDY DESIGN: A qualitative study. OBJECTIVE: The aim of this study was to understand expectations of persons with paraplegia in India regarding their care. SETTING: India. METHODS: This study used a qualitative methodology to have a focus group interview of persons with paraplegia in India. Focus group consisted of two to four participants with paraplegia. Adults with level T6 and below, complete injury, duration of at least 6 months post injury and those living in the community were included...
2017: Spinal Cord Series and Cases
Hortensia De la Corte-Rodriguez, E Carlos Rodriguez-Merchan, M Teresa Alvarez-Roman, Ana L Hernandez-Moreno
We present the case of two patients aged 12 years and 7 years who were referred to our hospital for factor VII deficiency inherited in an autosomal recessive pattern, who had suffered from previous multiple joint haemarthroses. They presented with fine motor symptoms and difficulty in walking. During physical examination we observed neurological symptoms (general hypotonia, muscular hypotrophy, exaggerated tendon reflexes, pes cavus, and spastic gait). Given that the symptoms were not justified by the deficiency of coagulation factor VII and on suspicion of hereditary spastic paraplegia (HSP), tests were carried out...
2016: Case Reports in Hematology
S Boubacar, N S Diagne, D W Ben Adji, A M Diop, M Seydi, Y Maiga, K Toure, M Ndiaye, A G Diop, M M Ndiaye
Nervous localisations of schistosomiasis are rare. We report the case of a 25 year-old Senegalese patient admitted for a progressive myeloradiculitis onset, over a one week period. The diagnosis of Schistosoma haematobium myeloradiculitis was made in front of a positive serum serology for S. haematobium, presence of S. haematobium eggs in urine, hyperproteinorachia, endemicity of S. haematobium in the region where the patient was originating and a past medical history of macroscopic hematuria in a context of river bathing...
May 2016: Bulletin de la Société de Pathologie Exotique
Cory Sims, Rennie Waldron, Denis J Marcellin-Little
A comprehensive physiotherapy plan for neurology patients manages pain, prevents secondary complications, and supports the health and function of musculoskeletal tissues during recovery. Neurologically impaired patients range in ability from complete immobility (tetraplegia/paraplegia), partial mobility (tetraparesis/paraparesis), mild ataxia, to pain only. Important considerations for the design of a physiotherapy program include access to the patient, level of staff support, and safety of staff, patient, and client during treatments...
January 2015: Veterinary Clinics of North America. Small Animal Practice
Han Gil Seo, Byung-Mo Oh, Keewon Kim
Robot-assisted gait training has been investigated for restoring walking through activity-dependent neuroplasticity in persons with various neurologic disorders. This case report presents the outcome of robot-assisted gait training combined with physiotherapy in a 28-year-old man with pure hereditary spastic paraplegia. The patient participated in 25 training sessions over 6 weeks. Improvements were noted in his walking speed and balance after the training, but gait kinematics and kinetics showed no remarkable changes before and after the training...
February 2015: PM & R: the Journal of Injury, Function, and Rehabilitation
Shahnawaz Anwer, Ameed Equebal, Tushar J Palekar, M Nezamuddin, Osama Neyaz, Ahmad Alghadir
[Purpose] The aim of this study was to describe the effect of locomotor training on a treadmill for three individuals who have an incomplete spinal cord injury (SCI). [Subjects and Methods] Three indivduals (2 males, 1 female) with incomplete paraplegia participated in this prospective case series. All subjects participated in locomotor training for a maximum of 20 minutes on a motorized treadmill without elevation at a comfortable walking speed three days a week for four weeks as an adjunct to a conventional physiotherapy program...
June 2014: Journal of Physical Therapy Science
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