Laura Abraira, Estevo Santamarina, Sonia Cazorla, Alejandro Bustamante, Manuel Quintana, Manuel Toledo, Elena Fonseca, Laia Grau-López, Marta Jiménez, Jordi Ciurans, Juan Luis Becerra, Mónica Millán, María Hernández-Pérez, Pere Cardona, Mikel Terceño, Josep Zaragoza, David Cánovas, Teresa Gasull, Xavier Ustrell, Marta Rubiera, Mar Castellanos, Joan Montaner, Jose Álvarez-Sabín
OBJECTIVE: Blood biomarkers have not been widely investigated in poststroke epilepsy. In this study, we aimed to describe clinical factors and biomarkers present during acute stroke and analyze their association with the development of epilepsy at long term. METHODS: A panel of 14 blood biomarkers was evaluated in patients with ischemic and hemorrhagic stroke. Biomarkers were normalized and standardized using Z-scores. Stroke and epilepsy-related variables were also assessed: stroke severity, determined by National Institutes of Health Stroke Scale (NIHSS) score, stroke type and cause, time from stroke to onset of late seizures, and type of seizure...
October 2020: Epilepsia