Katharina Manten, Stephan Katzenschlager, Lukas E Brümmer, Stephani Schmitz, Mary Gaeddert, Christian Erdmann, Maurizio Grilli, Nira R Pollock, Aurélien Macé, Berra Erkosar, Sergio Carmona, Stefano Ongarello, Cheryl C Johnson, Jilian A Sacks, Verena Faehling, Linus Bornemann, Markus A Weigand, Claudia M Denkinger, Seda Yerlikaya
BACKGROUND: During the COVID-19 pandemic, antigen diagnostic tests were frequently used for screening, triage, and diagnosis. Novel instrument-based antigen tests (iAg tests) hold the promise of outperforming their instrument-free, visually-read counterparts. Here, we provide a systematic review and meta-analysis of the SARS-CoV-2 iAg tests' clinical accuracy. METHODS: We systematically searched MEDLINE (via PubMed), Web of Science, medRxiv, and bioRxiv for articles published before November 7th, 2022, evaluating the accuracy of iAg tests for SARS-CoV-2 detection...
April 29, 2024: Virology Journal