keyword

anesthesia for hepatectomy

keyword
https://read.qxmd.com/read/32019557/the-effect-of-low-central-venous-pressure-on-hepatic-surgical-field-bleeding-and-serum-lactate-in-patients-undergoing-partial-hepatectomy-a-prospective-randomized-controlled-trial
#1
Ling Yu, Hongwei Sun, Huangmo Jin, Hongyu Tan
BACKGROUND: This prospective randomized controlled study was designed to evaluate the effect of fluid restriction alone versus fluid restriction + low central venous pressure (CVP) on hepatic surgical field bleeding, intraoperative blood loss, and the serum lactate concentration in patients undergoing partial hepatectomy. METHODS: One hundred forty patients undergoing partial hepatectomy with intraoperative portal triad clamping were randomized into a fluid restriction group (Group F) or fluid restriction + low CVP group (Group L)...
February 4, 2020: BMC Surgery
https://read.qxmd.com/read/31865521/autophagy-dysfunction-and-mtor-hyperactivation-is-involved-in-surgery-induced-behavioral-deficits-in-aged-c57bl-6j-mice
#2
Yanhua Jiang, Yongjian Zhou, Hong Ma, Xuezhao Cao, Zhe Li, Fengshou Chen, Hongnan Wang
Autophagy is crucial for cell survival, development, division, and homeostasis. The mammalian target of rapamycin (mTOR), which is the foremost negative controller of autophagy, plays a key role in many endogenous processes. The present study investigated whether rapamycin can ameliorate surgery-induced cognitive deficits by inhibiting mTOR and activating autophagy in the hippocampus. Both adult and aged C57BL/6J mice received an intraperitoneal injection of rapamycin (10 mg/kg/day) for 5 days per week for one and a half months...
February 2020: Neurochemical Research
https://read.qxmd.com/read/31743196/effect-of-remote-ischemic-preconditioning-in-patients-undergoing-hepatectomy-with-portal-triad-clamping-a-randomized-controlled-trial
#3
Xiaoqing Liu, Longhui Cao, Tianhua Zhang, Rongping Guo, Wenqian Lin
BACKGROUND: Remote ischemic preconditioning (RIPC) is reported to reduce liver injury in patients undergoing hepatectomy for colorectal liver metastasis, but its role is unclear in hepatocellular carcinoma patients with portal triad clamping during hepatectomy. METHODS: In this prospective, randomized trial, 140 patients with hepatocellular carcinoma undergoing liver resection requiring portal triad clamping were randomized to a RIPC group or a control group. Patients in the RIPC group received RIPC (3 cycles of 5-minute ischemia and 5-minute reperfusion in right upper limb with cuff pressure at 30 kPa [225 mm Hg]) approximately 10 minutes after induction of anesthesia...
December 2019: Anesthesia and Analgesia
https://read.qxmd.com/read/31669050/dexmedetomidine-exerts-a-protective-effect-on-ischemia-reperfusion-injury-after-hepatectomy-a-prospective-randomized-controlled-study
#4
Yu Zhang, Miao Liu, Yu Yang, Jiangbei Cao, Weidong Mi
STUDY OBJECTIVE: Dexmedetomidine, a highly selective α2 -receptor agonist, has been widely used for protection against ischemia-reperfusion (IR) injury. We hypothesized that dexmedetomidine might exert a protective effect on IR injury after hepatectomy. DESIGN: A prospective, randomized, single-blind study was conducted in 58 patients undergoing hepatectomy who were randomly assigned to two study groups. The dexmedetomidine group (D group) received a loading dose of 0...
October 25, 2019: Journal of Clinical Anesthesia
https://read.qxmd.com/read/31614325/effect-of-hydroxyethyl-starch-loading-on-glycocalyx-shedding-and-cerebral-metabolism-during-surgery
#5
Xueyan Li, Shen Sun, Gang Wu, Xuehua Che, Jun Zhang
BACKGROUND: Fluid therapy influences glycocalyx shedding; however, the effect of this intervention on glycocalyx shedding in patients with glioma remains unclear. In this study, we have investigated glycocalyx shedding and cerebral metabolism during colloid loading in patients with and without glioma. METHODS: Forty patients undergoing general anesthesia were assigned to the glioma brain group (n = 20) or the normal brain group (n = 20); patients in the normal brain group were undergoing partial hepatectomy to treat liver cancer...
October 12, 2019: Journal of Surgical Research
https://read.qxmd.com/read/31583432/two-stage-goal-directed-therapy-protocol-for-non-donor-open-hepatectomy-an-interventional-before-after-study
#6
Kazuyuki Mizunoya, Tomoaki Fujii, Masataka Yamamoto, Nobuhiro Tanaka, Yuji Morimoto
PURPOSE: Hemodynamic management during low central venous pressure (L-CVP)-assisted hepatectomy involves fluid restriction during resection and fluid resuscitation after resection. Recently, high stroke volume variation (SVV) has been reported as an alternative to L-CVP for reducing blood loss during a hepatectomy. The current study evaluated the impact of a newly implemented SVV-based goal-directed therapy (GDT) protocol on blood loss during hepatectomy. METHODS: We conducted a before-after comparative study, which included L-CVP-assisted hepatectomy cases (control group) and GDT-assisted hepatectomy cases (intervention group)...
October 3, 2019: Journal of Anesthesia
https://read.qxmd.com/read/31517678/effect-of-remote-ischemic-preconditioning-in-patients-undergoing-hepatectomy-with-portal-triad-clamping-a-randomized-controlled-trial
#7
Xiaoqing Liu, Longhui Cao, Tianhua Zhang, Rongping Guo, Wenqian Lin
BACKGROUND: Remote ischemic preconditioning (RIPC) is reported to reduce liver injury in patients undergoing hepatectomy for colorectal liver metastasis, but its role is unclear in hepatocellular carcinoma patients with portal triad clamping during hepatectomy. METHODS: In this prospective, randomized trial, 140 patients with hepatocellular carcinoma undergoing liver resection requiring portal triad clamping were randomized to a RIPC group or a control group. Patients in the RIPC group received RIPC (3 cycles of 5-minute ischemia and 5-minute reperfusion in right upper limb with cuff pressure at 30 kPa [225 mm Hg]) approximately 10 minutes after induction of anesthesia...
September 10, 2019: Anesthesia and Analgesia
https://read.qxmd.com/read/31500771/robotic-right-hepatectomy-for-a-central-liver-tumor-a-video-of-the-surgical-technique
#8
Carolijn L M A Nota, I Quintus Molenaar, Inne H M Borel Rinkes, Jeroen Hagendoorn
BACKGROUND: Robotic surgery is gaining momentum in liver resection. Instrumentation of the surgical robot is articulated, movements are scaled and the view of the operative field is 3-dimensional and magnified[1, 2]. Thus, these technical enhancements allow for a more precise dissection and curved work axes, as needed in liver resection. Aim of this video was to demonstrate the feasibility of fully robotic right hepatectomy with dissection of the variant right hepatic pedicles for a centrally located liver tumor...
September 2019: Surgical Oncology
https://read.qxmd.com/read/31388780/abdominal-drain-straying-into-right-atrium-a-case-report
#9
Junya Toyoda, Hitoshi Sekido, Kazuhisa Takeda, Tetsuya Shimizu, Goro Matsuda
BACKGROUND: A drain exchange with the use of a guidewire may be accompanied by serious complications. CASE PRESENTATION: This case involved an 86-year-old man with overlapping cancers of intrahepatic cholangiocarcinoma and perihilar cholangiocarcinoma. A left hepatectomy, a left caudal lobectomy (with a medial hepatic vein preservation), an extrahepatic bile duct resection, and a right hepatojejunostomy were performed. The abdominal drain was placed into the hepatectomy side...
August 6, 2019: Surgical Case Reports
https://read.qxmd.com/read/31216172/portal-hyperperfusion-after-major-liver-resection-and-associated-sinusoidal-damage-is-a-therapeutic-target-to-protect-the-remnant-liver
#10
Andreas Kohler, Per Werner Moller, Sabrina Frey, Pascale Tinguely, Daniel Candinas, Dominik Obrist, Stephan Matthias Jakob, Guido Beldi
Extended liver resection results in the loss of a large fraction of the hepatic vascular bed and thereby abrupt alterations in the perfusion of the remnant liver. Mechanisms of hemodynamic adaptation and associated changes in oxygen metabolism after liver resection and the effect of mechanical portal blood flow reduction were assessed. A pig model (n=16) of extended partial hepatectomy that included continuous observation for 24 hours under general anesthesia was established. Pigs were randomly separated into 2 groups, one group with a portal flow reduction of 70% compared to the preoperative values, and the other group as a control (n=8, each)...
June 19, 2019: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://read.qxmd.com/read/30878355/perioperative-management-for-gastrointestinal-surgery-after-instituting-interventions-initiated-by-the-japanese-society-of-surgical-metabolism-and-nutrition
#11
Masaki Kaibori, Go Miyata, Kengo Yoshii, Ryoji Fukushima
BACKGROUND: In 2012, the Japanese Society for Surgical Metabolism and Nutrition introduced the Essential Strategy for Early Normalization after Surgery with Patient's Excellent Satisfaction (ESSENSE) program to improve the perioperative management of gastrointestinal surgery. The ESSENSE program aimed to minimize ineffective perioperative management practices, and achieve adequate analgesia to expedite the return to work and activities of daily living. METHODS: After educating relevant facilities about the ESSENSE program in 2012, we conducted questionnaire-based surveys in selected institutions in 2013 and 2016...
March 13, 2019: Asian Journal of Surgery
https://read.qxmd.com/read/30798741/intrathecal-morphine-administration-does-not-affect-survival-after-liver-resection-for-hepatocellular-carcinoma
#12
Natalie K Smith, Samuel Demaria, Daniel Katz, Parissa Tabrizian, Myron Schwartz, Joanna C Miller, Bryan Hill, Brielle Cardieri, Sang J Kim, Jeron Zerillo
INTRODUCTION: Opioids may influence tumor recurrence and cancer-free survival in hepatocellular carcinoma (HCC). The relationship between intrathecal morphine administration, tumor recurrence, and patient survival after hepatectomy for HCC is unknown. PATIENTS AND METHODS: This single-center, retrospective study included 1837 liver resections between July 2002 and December 2012; 410 cases were incorporated in the final univariate and multivariate analysis. Confirmatory propensity matching yielded 65 matched pairs (intrathecal morphine vs none)...
February 24, 2019: Seminars in Cardiothoracic and Vascular Anesthesia
https://read.qxmd.com/read/30773451/effect-of-pharmacological-preconditioning-with-sevoflurane-during-hepatectomy-with-intermittent-portal-triad-clamping
#13
Truong Minh Nguyen, Maher Fleyfel, Emmanuel Boleslawski, Léna M'Ba, Marie Geniez, Sabine Ethgen, Hélène Béhal, Gilles Lebuffe
BACKGROUND: During hepatectomy, intermittent portal triad clamping (IPC) reduces ischemia-reperfusion injuries. Pharmacological preconditioning with sevoflurane revealed similar properties. The aim of the study was to evaluate the combination of a sevoflurane preconditioning regimen with IPC on ischemia-reperfusion injuries. METHODS: Three regimens of anesthesia were applied: group SEV with continuous application of sevoflurane, group PRO with continuous propofol infusion and group PC where continuous propofol was substituted by sevoflurane (adjusted to reach MAC∗1...
February 15, 2019: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://read.qxmd.com/read/30704965/is-robotic-hepatectomy-cost-effective-in-view-of-patient-reported-outcomes
#14
Chao-Ying Wu, Po-Da Chen, Wei-Han Chou, Jin-Tung Liang, Chiun-Sheng Huang, Yao-Ming Wu
BACKGROUND: Robotic hepatectomy has been accepted as an alternative for patients needing surgery. However, few reports addressed the patient-reported outcomes and long-term quality of life (QoL) of patients having undergone robotic liver surgery. METHODS: This study presented the QoL and cost-effectiveness associated with robotic and open hepatectomy by performing a comparative survey using two standardized questionnaires (Short Form-36 and Gastrointestinal Quality of Life Index)...
January 28, 2019: Asian Journal of Surgery
https://read.qxmd.com/read/30692895/living-donor-liver-transplantation-in-a-patient-with-cocoon-abdomen-anesthesia-concerns
#15
Neha Garg, Gaurav Sindwani, Mahesh Kumar Arora, Vinyendra Pamecha
Cocoon abdomen is a rare condition in which abdominal structures are surrounded by thick encapsulating peritoneum resulting in dense adhesions. Liver transplant is a high risk surgery with an already increased risk of massive blood loss due to the pre-existing coagulopathy and portal hypertension. Presence of cocoon abdomen with severe dense adhesions can either lead to difficult hepatectomy with massive intra-operative blood loss or failure to proceed with the surgery. This becomes even more important in live donor liver transplantation where it may not be possible to abandon the surgery once the donor liver resection is started...
January 2019: Saudi Journal of Anaesthesia
https://read.qxmd.com/read/30606815/the-effects-of-terlipressin-and-direct-portacaval-shunting-on-liver-hemodynamics-following-80-hepatectomy-in-the-pig
#16
John S Hammond, Fred Godtliebsen, Sonja Steigen, Indra Neil Guha, Judy Wyatt, Arthur Revhaug, Dileep N Lobo, Kim E Mortensen
Liver failure is the major cause of death following liver resection. Post-resection portal venous pressure (PVP) predicts liver failure, is implicated in its pathogenesis and when PVP is reduced, rates of liver dysfunction decrease. The aim of this study was to characterize the hemodynamic, biochemical and histological changes induced by 80% hepatectomy in non-cirrhotic pigs and determine if terlipressin or direct portacaval shunting can modulate these effects.Pigs were randomized (n=8/group) to undergo 80% hepatectomy alone (control); terlipressin (2 mg bolus + 0...
January 3, 2019: Clinical Science (1979-)
https://read.qxmd.com/read/30505962/optimizing-hepatectomy-for-hepatocellular-carcinoma-in-asia-patient-selection-and-special-considerations
#17
REVIEW
Clarence Nicholas Kotewall, Tan To Cheung
Hepatocellular carcinoma (HCC) is a common affliction in Asia. The treatment of HCC depends on the tumor status as well as the underlying liver function. Resection is the cornerstone of surgical management of HCC. For those unfit to undergo resection, local ablative therapy is a viable alternative. For patients with multiple small unresectable HCCs, liver transplantation offers another option, having the simultaneous benefit of removing the cancer in addition to replacing the pre-malignant and cirrhotic liver together...
2018: Translational Gastroenterology and Hepatology
https://read.qxmd.com/read/30477577/pain-management-in-living-related-adult-donor-hepatectomy-feasibility-of-an-evidence-based-protocol-in-100-consecutive-donors
#18
Guillaume Dewe, Arnaud Steyaert, Marc De Kock, Fernande Lois, Raymond Reding, Patrice Forget
OBJECTIVE: Living donor hepatectomy (LDH) has important consequences in terms of acute and chronic pain. We proposed an anesthetic protocol based on the best currently available evidence. We report the results of this protocol's application. RESULTS: We performed a retrospective descriptive study of 100 consecutive donors undergoing LDH. The protocol included standardized information provided by the anesthetist, pharmacological anxiolysis and preventive analgesia...
November 26, 2018: BMC Research Notes
https://read.qxmd.com/read/30401370/anesthesia-management-and-fluid-therapy-in-right-and-left-lobe-living-donor-hepatectomy
#19
C-H Wang, K-A Chang, C-L Chen, K-W Cheng, S-C Wu, C-J Huang, T-H Shih, S C Yang, S-E Juang, C-E Huang, B Jawan, Y-E Lee
OBJECTIVE: Right lobe living donor hepatectomy poses a greater risk for the donor in relation to blood loss. The aims of this study were to compare anesthetic and intraoperative fluid management in right and left lateral segment living donor hepatectomy. PATIENTS AND METHODS: The anesthesia records of living donor hepatectomy patients were retrospectively reviewed. Donor age and weight, anesthesia time, central venous pressure, blood loss, blood product transfusion, intravenous fluids used, doses of furosemide, and urine output were compared and analyzed between groups using the Mann Whitney U test...
November 2018: Transplantation Proceedings
https://read.qxmd.com/read/30100839/use-of-ultrasound-guided-preoperative-diaphragmatic-thickness-as-a-predictor-of-postoperative-weaning-failure-in-recipients-and-donors-scheduled-for-living-donor-liver-transplant-surgery
#20
Ankur Sharma, Sunaina Tejpal Karna, Manish Tandon, Chandra Kant Pandey, Ravindra Chaturvedi, Varuna Vyas, Akhil Dhanesh Goel
Background and Objectives: The present study was designed to explore the utility of ultrasound-guided diaphragmatic thickness in the preoperative period in healthy controls scheduled for live-related donor hepatectomy and patients suffering from chronic liver disease scheduled for liver transplantation (LT) and its use as a predictor of postoperative weaning failure. Materials and Methods: This prospective observational study was conducted in a tertiary health care center and 65 adult (18-70 years) participants (30 healthy liver donors and 35 liver transplant recipients) were enrolled for this study...
July 2018: Saudi Journal of Anaesthesia
keyword
keyword
65075
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"