Anderson Cargnin-Carvalho, Mariella Reinol Silva, Ana Beatriz Costa, Nicole Alessandra Engel, Bianca Xavier Farias, Joice Benedet Bressan, Kassiane Mathiola Backes, Francielly de Souza, Naiana da Rosa, Aloir Neri de Oliveira Junior, Mariana Pereira de Souza Goldim, Maria Eduarda Anastácio Borges Corrêa, Ligia Milanez Venturini, Jucélia Jeremias Fortunato, Josiane Somariva Prophiro, Fabricia Petronilho, Paulo Cesar Lock Silveira, Gabriela Kozuchovski Ferreira, Gislaine Tezza Rezin
Excessive fructose consumption is associated with the incidence of obesity and systemic inflammation, resulting in increased oxidative stress and damage to the function of brain structures. Thus, we hypothesized that fructose consumption will significantly increase inflammation, oxidative damage and mitochondrial dysfunction in the mouse brain and, consequently, memory damage. The effects of different fructose concentrations on inflammatory and biochemical parameters in the mouse brain were evaluated. Male Swiss mice were randomized into four groups: control, with exclusive water intake, 5%, 10% and 20% fructose group...
March 22, 2023: Biochemistry and Cell Biology