Robert Gajda
Background: Diet and physical activity are very important lifestyle features with an impact on the development and proper functioning of the body. Objective: The aim of the study was to assess the relationship between the level of physical activity and selected somatic indicators and the diet quality of students studying in the field of Health Sciences. Material and methods: The studied group consisted of 609 students aged 18-30. The study identified four categories of diet quality indicators based on the index of a healthy diet and the index of an unhealthy diet...
2020: Roczniki Państwowego Zakładu Higieny
Ewa Piotrowska, Danuta Figurska-Ciura, Karolina Łoźna, Maciej Bienkiewicz, Dominika Mazurek, Joanna Wyka, Marcelina Węgiel, Jadwiga Biernat, Michaela Godyla-Jabłoński
Background: A recently growing number of children and adolescents with overweight or obesity is indicative of the need for diagnosing their complications that may appear in the early childhood. For this reason, diagnostic criteria were developed for components of the metabolic syndrome (MS) also for these groups of the population. Objective: This study was aimed at evaluating the frequency of metabolic syndrome risk factors occurrence in children and adolescents from the city of Wrocław and surroundings depending on gender, age and physical activity...
2020: Roczniki Państwowego Zakładu Higieny
Paweł Glibowski, Magdalena Ćwiklińska, Agnieszka Białasz, Wojciech Koch, Zbigniew Marzec
Background: Overweight and obesity are a problem negatively affecting human health. Besides the excess of energy from food, development of overweight can also result from food preferences, the frequency of meals and the speed of eating. Objective: The aim of this study was to analyse the effect of eating habits and physical activity on the occurrence of overweight and obesity. Material and method: The questionnaire survey concerning eating habits and physical activity was conducted among adults aged 20-59 (n=420) in Lublin province (Poland)...
2020: Roczniki Państwowego Zakładu Higieny
Andrew G Rundle, Yoosun Park, Julie B Herbstman, Eliza W Kinsey, Y Claire Wang
The COVID-19 pandemic is causing substantial morbidity and mortality, straining health care systems, shutting down economies, and closing school districts. While it is a priority to mitigate its immediate impact, we want to call attention to the pandemic's longer-term effect on children's health: COVID-19, via these school closures, may exacerbate the epidemic of childhood obesity and increase disparities in obesity risk. In many areas of the U.S., the COVID-19 pandemic has closed schools and some of these school systems are not expected to re-open this school year...
March 30, 2020: Obesity
Sophia Berkemeier, Kate Cheney, Rachel Farber, Kyra A Sim, Kirsten I Black
This prospective cross-sectional study of 1498 pregnant women in early pregnancy sought to investigate the prevalence of pregnancy intention between women of differing body mass index (BMI) categories. There was no difference in the risk of unintended pregnancy between women who were in the healthy weight, overweight or obesity BMI categories. The study identifies and highlights the potential missed opportunities for all women to engage in healthy reproductive life planning behaviours to support health in pregnancy and beyond...
March 29, 2020: Australian & New Zealand Journal of Obstetrics & Gynaecology
Francesco Paolo Prete, Angela Gurrado, Alessandro Pasculli, Lucia Ilaria Sgaramella, Giovanni Catalano, Pierluca Nicola Massimo Sallustio, Giuseppe Carbotta, Paolo Ialongo, Giuseppe Cavallaro, Mario Testini
PURPOSE: To investigate the safety and outcomes of laparoscopic control of intraperitoneal mesh positioning in open umbilical hernia repair. METHODS: This study is a retrospective review of a series of adult patients with uncomplicated umbilical hernia who underwent elective open repair with a self-expanding patch with laparoscopic control from March 2011 to December 2018. The adequacy of mesh positioning was inspected with a 5-mm 30° scope in the left flank. The primary endpoint was recurrence...
March 30, 2020: Surgical Technology International
Carlucci Gualberto Ventura, Felício Lopes Roque, Itanilton Queiroz de Sousa, Renata Desordi Lobo, Claudio Luders
INTRODUCTION: Chronic hemodialysis (HD) patients are considered to be at high risk for infection. Here, we describe the clinical outcomes of chronic HD patients with influenza A (H1N1) infection and the strategies adopted to control an outbreak of influenza A in a dialysis unit. METHODS: Among a total of 62 chronic HD patients, H1N1 infection was identified in 12 (19.4%). Of the 32 staff members, four (12.5%) were found to be infected with the H1N1 virus. Outcomes included symptoms at presentation, comorbidities, occurrence of hypoxemia, hospital admission, and clinical evaluation...
March 23, 2020: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
J C Nwanaji-Enwerem, A Landry
A 29-year-old woman with a history of obesity status post Roux-en-Y gastric bypass greater than five years prior presented to the emergency department with four hours of sudden-onset stabbing left-sided abdominal pain associated with nausea and non-bloody emesis. She denied melaena and hematochezia, but did report two weeks of diarrhoea that was unchanged with this new onset abdominal pain.
2020: Acute Medicine
Gary J Farkas, David R Gater
No abstract text is available yet for this article.
2020: J Phys Med Rehabil
Arjun Sinha, Clyde W Yancy, Sanjiv J Shah, Sadiya S Khan
The authors report a case of heart failure with preserved ejection fraction in a post-menopausal woman with obesity. The case highlights a metabolic phenotype of heart failure with preserved ejection fraction that commonly presents in women with discussion focusing on the pathophysiology, mechanistic pathways, and potential targeted therapeutic strategies.
January 2020: JACC. Case reports
Kyle W Scott, Jonathan Arias, Kourosh Tavanaiepour, Daryoush Tavanaiepour, Gazanfar Rahmathulla
Traumatic lumbosacral dissociation is a unique, but well-documented, phenomenon that generally stems from high-energy impact injuries to the lower lumbar spine. Patients typically present with complicated and multisystem injuries with wide-ranging neurological deficits below the level of trauma. This presents stark challenges regarding the diagnosis, management, and surgical correction technique utilized. In this study, we present the case of a 21-year-old, morbidly obese, male patient that presented after a traumatic motor vehicle accident with L5-S1 lumbosacroiliac dissociation, cauda equina syndrome, and left lower extremity monoplegia...
February 24, 2020: Curēus
Amir M Pirmoazen, Aman Khurana, Ahmed El Kaffas, Aya Kamaya
Nonalcoholic fatty liver disease is a major global health concern with increasing prevalence, associated with obesity and metabolic syndrome. Recently, quantitative ultrasound-based imaging techniques have dramatically improved the ability of ultrasound to detect and quantify hepatic steatosis. These newer ultrasound techniques possess many inherent advantages similar to conventional ultrasound such as universal availability, real-time capability, and relatively low cost along with quantitative rather than a qualitative assessment of liver fat...
2020: Theranostics
Cai Liang, Kevin Y Yang, Vicken W Chan, Xisheng Li, Tiffany H W Fung, Yalan Wu, Xiao Yu Tian, Yu Huang, Ling Qin, James Y W Lau, Kathy O Lui
In this study, we observe that the ischemic tissues of type-2 diabetic (T2D) patients and mice have significantly more CD8+ T-cells than that of their normoglycemic counterparts, respectively. However, the role of CD8+ T-cells in the pathogenesis of diabetic vascular complication has been less studied. Methods : We employed loss-of-function studies in mouse models using the non-lytic anti-CD8 antibody that blocks tissue infiltration of CD8+ T-cells into the injured tissue. We also performed genome-wide, single-cell RNA-sequencing of CD8+ T-cells to uncover their role in the pathogenesis of diabetic vascular diseases...
2020: Theranostics
Shuai Wang, Feng Li, Yanke Lin, Baojian Wu
REV-ERBα (NR1D1) is a circadian clock component that functions as a transcriptional repressor. Due to its role in direct modulation of metabolic genes, REV-ERBα is regarded as an integrator of cell metabolism with circadian clock. Accordingly, REV-ERBα is first proposed as a drug target for treating sleep disorders and metabolic syndromes (e.g., dyslipidaemia, hyperglycaemia and obesity). Recent years of studies uncover a rather broad role of REV-ERBα in pathological conditions including local inflammatory diseases, heart failure and cancers...
2020: Theranostics
Chao-Qun Wang, Chih-Hsin Tang, Huey-En Tzeng, Lulu Jin, Jin Zhao, Le Kang, Yan Wang, Gui-Nv Hu, Bi-Fei Huang, Xiaoni Li, Yong-Ming Zhao, Chen-Ming Su, Hong-Chuan Jin
The adipokine resistin is linked with obesity, inflammation and various cancers, including breast cancer. This study sought to determine whether certain polymorphisms in the gene encoding resistin, RETN, increase the risk of breast cancer susceptibility. We analyzed levels of resistin expression in breast cancer tissue and samples from The Cancer Genome Atlas database. We also examined associations between four RETN single nucleotide polymorphisms (SNPs; rs3745367, rs7408174, rs1862513 and rs3219175) and breast cancer susceptibility in 515 patients with breast cancer and 541 healthy women without cancer...
2020: Journal of Cancer
Bogang Wu, Xiujie Sun, Bin Yuan, Fei Ge, Harshita B Gupta, Huai-Chin Chiang, Jingwei Li, Yanfen Hu, Tyler J Curiel, Rong Li
Immune checkpoint blockade-based immunotherapy has become standard of care for multiple cancer types. However, the overall response rates among various cancer types still remain unsatisfactory. There is a pressing clinical need to identify combination therapies to improve efficacy of anticancer immunotherapy. We previously showed that pharmacologic inhibition of PPARγ by GW9662 boosts αPD-L1 and αPD-1 antibody efficacy in treating murine mammary tumors. In addition, we defined sexually dimorphic αPD-L1 efficacy in B16 melanoma...
2020: International Journal of Biological Sciences
David Houghton, Matthew D Wilcox, Iain A Brownlee, Peter I Chater, Chris J Seal, Jeffrey P Pearson
Lifestyle interventions and physical activity remain the cornerstone of obesity management, as pharmacological therapies (orlistat) are associated with gastrointestinal (GI) side effects. Combining orlistat with fibers can reduce side effects, improving compliance. Therefore, a fiber that inhibits lipase without side effects could help treat obesity. The aims of the present work were to assess whether alginate enriched bread could inhibit fat digestion, and assess the acceptability of alginate bread and its effect on GI wellbeing...
August 2019: Food Hydrocolloids
Giota Touloumi, Natasa Kalpourtzi, Vasileios Papastamopoulos, Vasilios Paparizos, Georgios Adamis, Anastasia Antoniadou, Maria Chini, Argiro Karakosta, Konstantinos Makrilakis, Magda Gavana, Apostolos Vantarakis, Mina Psichogiou, Simeon Metallidis, Nikolaos V Sipsas, Helen Sambatakou, Christos Hadjichristodoulou, Paraskevi V Voulgari, George Chrysos, Charalambos Gogos, Grigoris Chlouverakis, Grigoris Tripsianis, Yannis Alamanos, George Stergiou
BACKGROUND: Although combined antiretroviral therapy has substantially improved the prognosis of people living with HIV (PLHIV), mortality remains higher compared to the general population, mainly due to higher prevalence of non-HIV-related comorbidities, including cardiovascular diseases (CVD). We assessed the prevalence of CVD risk and its contributing factors in adult PLHIV versus general population controls in Greece. SETTINGS: Cross-sectional comparison of PLHIV (Athens-Multicenter-AIDS-Cohort-Study; AMACS) versus general population controls (National health examination survey; EMENO)...
2020: PloS One
Linda Aurpibul, Sirianong Namwongprom, Tavitiya Sudjaritruk, Sakaewan Ounjaijean
People living with HIV who are on antiretroviral treatment are at increased risk of developing premature cardiovascular disease. Children with perinatal HIV infection (PHIV) have survived through their adolescence and are entering adulthood. We determined the prevalence of metabolic syndrome, abnormal biochemical markers, and characterized body composition parameters in youth living with perinatal HIV infection. This cross-sectional study was conducted at the Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand from December 2017 to February 2018...
2020: PloS One
Amparo L de la Fuente-Reynoso, Enrique Romero-Velarde, Claudia E Hunot-Alexander, Edgar M Vásquez-Garibay, Alethia G Mariscal-Rizo
Background: Overweight and obesity in schoolchildren are a major public health problem in Mexico. The objective of this study was to demonstrate the association of appetitive traits with the presence of obesity and identify gender differences in children attending a university hospital. Methods: A cross-sectional study was conducted on 176 children with obesity and 175 children with normal weight in the outpatient clinic of the Nuevo Hospital Civil de Guadalajara...
2020: Boletín Médico del Hospital Infantil de México
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