Jane J Reavey, Catherine Walker, Alison A Murray, Savita Brito-Mutunayagam, Sheona Sweeney, Moira Nicol, Ana Cambursano, Hilary O D Critchley, Jacqueline A Maybin
Heavy menstrual bleeding is common and debilitating but the causes remain ill defined. Rates of obesity in women are increasing and its impact on menstrual blood loss (MBL) is unknown. Therefore, we quantified BMI and MBL in women not taking hormones and with regular menstrual cycles and revealed a positive correlation. In a mouse model of simulated menstruation, diet-induced obesity also resulted in delayed endometrial repair, a surrogate marker for MBL. BrdU staining of mouse uterine tissue revealed decreased proliferation during menstruation in the luminal epithelium of mice on a high-fat diet...
May 2021: Journal of Endocrinology
Madeline Palermo, Cody Staples, Diana Rancourt
OBJECTIVE: Though exercise behaviors are typically viewed as health-promoting, certain forms of exercise (i.e., excessive exercise, unhealthy muscle-building behaviors) are considered maladaptive and are associated with negative physical and psychological outcomes. Psychosocial factors may put people at greater risk for engaging in maladaptive exercise. Based on deviance regulation theory, weight bias was examined as a potential moderator of the association between exercise identity and both excessive exercise and muscle-building behaviors...
March 29, 2021: Eating Behaviors
J G Martins, T Kawakita, M Gurganus, D Baraki, P Jain, A T Papageorghiou, A Z Abuhamad
OBJECTIVES: Determine interobserver reproducibility of fetal ultrasound biometry and amniotic fluid assessment in the third trimester according to BMI categories. METHODS: Prospective cohort of women with singleton gestations beyond 34 weeks, recruited into 4 groups according to BMI categories: normal, overweight, obese and morbid obese. Multiple pregnancies, diabetes, growth and fetal abnormalities were excluded. Biometric and fluid measurements were obtained by two experienced physicians/sonographers, blinded for gestational age and each other's measurements...
April 9, 2021: Ultrasound in Obstetrics & Gynecology
Preeti Pathela, Addie Crawley, Don Weiss, Beth Maldin, Jennifer Cornell, Jeff Purdin, Pamela K Schumacher, Stacey Marovich, Joyce Li, Demetre Daskalakis
BACKGROUND: New York City (NYC) was the U.S. epicenter of the Spring 2020 COVID-19 pandemic. We present seroprevalence of SARS-CoV-2 infection and correlates of seropositivity immediately after the first wave. METHODS: From a serosurvey of adult NYC residents (May 13-July 21, 2020), we calculated the prevalence of SARS-CoV-2 antibodies stratified by participant demographics, symptom history, health status, and employment industry. We used multivariable regression models to assess associations between participant characteristics and seropositivity...
April 9, 2021: Journal of Infectious Diseases
Orsolya Kiss, Mate Babity, Attila Kovacs, Judit Skopal, Hajnalka Vago, Balint Karoly Lakatos, Csaba Bognar, Reka Rakoczi, Mark Zamodics, Lorinc Frivaldszky, Anna Menyhart-Hetenyi, Zsofia Dohy, Csilla Czimbalmos, Liliana Szabo, Bela Merkely
The significance of cardiology screening of referees is not well established. Cardiovascular risk factors and diseases were examined in asymptomatic Hungarian elite handball referees undergoing extended screening: personal/family history, physical examination, 12-lead ECG, laboratory tests, body-composition analysis, echocardiography, and cardiopulmonary exercise testing. Holter-ECG (n = 8), blood pressure monitorization (n = 10), cardiac magnetic resonance imaging (CMR; n = 27) and computer tomography (CCT; n = 4) were also carried out if needed...
2021: PloS One
Linnea Österberg, Iván Domenzain, Julia Münch, Jens Nielsen, Stefan Hohmann, Marija Cvijovic
The interplay between nutrient-induced signaling and metabolism plays an important role in maintaining homeostasis and its malfunction has been implicated in many different human diseases such as obesity, type 2 diabetes, cancer, and neurological disorders. Therefore, unraveling the role of nutrients as signaling molecules and metabolites together with their interconnectivity may provide a deeper understanding of how these conditions occur. Both signaling and metabolism have been extensively studied using various systems biology approaches...
April 9, 2021: PLoS Computational Biology
Sarah E Barlow, Olga T Gupta, Sarah E Messiah, Christy Boling Turer
No abstract text is available yet for this article.
April 2021: Childhood Obesity
Jae Rim Kim, Pamela Song, Eun Yeon Joo
BACKGROUND AND PURPOSE: Obesity is known of one of the risk factors for obstructive sleep apnea (OSA). Although body mass index (BMI) can be an indicator for obesity, it does not represent the actual body composition of fat or muscle. We hypothesized that bioelectrical impedance analysis (BIA) can help analyze the fat and muscle distributions in males and females with OSA. METHODS: This study screened subjects who visited the Department of Neurology, Samsung Medical Center, Seoul, Korea due to sleep disturbances with symptoms suggestive of OSA from December 2017 to December 2019...
April 2021: Journal of Clinical Neurology
Thomas J Wilkinson, Katherine Memory, Courtney J Lightfoot, Jared Palmer, Alice C Smith
BACKGROUND: Patient activation describes the knowledge, skills and confidence in managing one's own health. Promoting patient activation is being prioritized to reduce costs and adverse outcomes such as cardiovascular disease (CVD). The increasing prevalence of chronic kidney disease (CKD) presents a need to understand the characteristics that influence patient activation and the effect on health outcomes. DESIGN: Cross-sectional study. SETTING AND PARTICIPANTS: Patients with non-dialysis CKD recruited from 14 sites (general nephrology and primary care) in England, UK...
April 9, 2021: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
Issei Komuro, Takashi Kadowaki, Johan Bodegård, Marcus Thuresson, Suguru Okami, Toshitaka Yajima
AIMS: To examine heart failure (HF) and chronic kidney disease (CKD) risks reduction associated with sodium-glucose cotransporter-2 inhibitors (SGLT-2i) compared to other glucose-lowering drugs (oGLD) in the early stage of type 2 diabetes patients without established cardiovascular or renal diseases (CVRD-free T2D). MATERIALS AND METHODS: We performed an observational cohort study using a Japanese hospital claims registry, Medical Data Vision. CVRD-free T2D patients were identified between 1 April 2014 and 30 September 2018...
April 2021: Diabetes, Obesity & Metabolism
Shun Kohsaka, Masayoshi Takeda, Yoko Kidani, Toshitaka Yajima
AIM: To examine healthcare resource utilization in type 2 diabetes (T2D) patients after initiation of sodium-glucose co-transporter-2 inhibitors (SGLT-2is) versus dipeptidyl peptidase-4 inhibitors (DPP-4is) or other glucose-lowering drugs (oGLDs). MATERIALS AND METHODS: A cost-utilization analysis was performed using a nationwide hospital-based administrative claims database (Medical Data Vision) during 2014-2018 in Japan, where universal healthcare coverage is maintained under a single-payer system...
April 2021: Diabetes, Obesity & Metabolism
Shun Kohsaka, Naru Morita, Suguru Okami, Yoko Kidani, Toshitaka Yajima
With the widespread use of electronic medical records and administrative claims databases, analytic results from so-called real-world data have become increasingly important in healthcare decision-making. Diabetes mellitus is a heterogeneous condition that involves a broad spectrum of patients. Real-world database studies have been recognised as a powerful tool to understand the impact of current practices on clinical courses and outcomes, such as long-term glucose control, development of microvascular or macro-vascular diseases, and mortality...
April 2021: Diabetes, Obesity & Metabolism
Christina Meade, Ruth Martin, Ann McCrann, Jacqueline Lyons, Edna Roche
BACKGROUND: The management of Prader-Willi Syndrome (PWS) requires strict dietary supervision to prevent obesity, avoid micronutrient deficiencies and ensure optimal growth. The present study aimed to examine the growth and dietary intake of children with PWS. METHODS: All children with genetically confirmed PWS attending Children's Health Ireland (CHI) at Tallaght (n = 44) were invited to participate. Anthropometry was performed and body composition measured using bioelectrical impedance analysis...
April 9, 2021: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
Casey K Gardiner, Angela D Bryan
OBJECTIVES: To test the effects of three behavioural interventions (daily monetary incentives + self-monitoring, delayed lump sum monetary incentives + self-monitoring, and self-monitoring only) on psychological constructs and fruit and vegetable consumption or physical activity behaviour change among a sample of adults with overweight or obesity. DESIGN: A pair of 3-arm longitudinal randomized controlled trials compared daily monetary incentives + self-monitoring, delayed lump sum monetary incentives + self-monitoring, and self-monitoring only interventions for either fruit and vegetable consumption or physical activity...
April 9, 2021: British Journal of Health Psychology
Martina De Feo, Rita Del Pinto, Silvia Pagliacci, Davide Grassi, Claudio Ferri
INTRODUCTION: Hypertesion is the leading cause of morbidity and mortality, worldwide, and its prevalence has been increasing in several countries, including Italy. AIMS: To assess hypertension prevalence, awareness, treatment, and control in a real-world sample of adults with self-reported diabetes compared with nondiabetic individuals. METHODS: Following the 2018 World Hypertension Day, a nationwide, cross-sectional epidemiological survey on cardiovascular risk factors ("Abbasso la Pressione!") in 3956 Italian pharmacies enrolled 47217 self-presenting volunteers (≥ 18 years)...
April 9, 2021: High Blood Pressure & Cardiovascular Prevention: the Official Journal of the Italian Society of Hypertension
Martina Valente, Sophie Renckens, Joske Bunders-Aelen, Elena V Syurina
PURPOSE: This mixed-methods study delved into the relationship between orthorexia nervosa (ON) and Instagram. METHODS: Two quantitative data sources were used: content analysis of pictures using #orthorexia (n = 3027), and an online questionnaire investigating the experience of ON and the use of Instagram of people sharing ON-related content on Instagram (n = 185). Following, interviews (n = 9) were conducted with people posting ON-related content on Instagram and self-identifying as having (had) ON...
April 9, 2021: Eating and Weight Disorders: EWD
Christine Chow, Robert J Mentz, Stephen J Greene
PURPOSE OF REVIEW: Multiple newer medications benefit patients with heart failure with reduced ejection fraction (HFrEF). While these therapies benefit the broad population with HFrEF, the efficacy and safety of these therapies have been less well characterized in patients with significant comorbidities. RECENT FINDINGS: Common comorbidities of high interest in heart failure (HF) include diabetes mellitus, chronic kidney disease (CKD), atrial fibrillation, and obesity, and each has potential implications for clinical management...
April 9, 2021: Current Heart Failure Reports
I A Rhemtulla, J Y Hsu, R B Broach, J T Mauch, J M Serletti, R P DeMatteo, J P Fischer
BACKGROUND: Incisional hernias (IH) following abdominal surgery persist as morbid, costly, and multi-disciplinary surgical challenges. Using longitudinal, multi-state, administrative claims data (HCUP State Inpatient Databases (SID)); (HCUP State Ambulatory Surgery and Services Databases (SASD)), we aimed to characterize the epidemiology, outcomes, recurrence, and costs of IH. STUDY DESIGN: 529,108 patients undergoing abdominal surgery in 2010 across six specialties (colorectal, general/bariatric, hepatobiliary, obstetrics/gynecology, urology, and vascular) were identified within inpatient and ambulatory databases for Florida (FL), Iowa (IA), Nebraska (NE), New York (NY), and Utah (UT)...
April 9, 2021: Hernia: the Journal of Hernias and Abdominal Wall Surgery
Judith K Ockene, Lori Pbert, Sybil Crawford, Christine F Frisard, Jyothi A Pendharkar, Rajani S Sadasivam, Jamie Faro, Cathy Okuliar, Cassie Eno, Katherine Margo, Monica Ann Shaw, Taraneh Soleymani, Diane D Stadler, Sarita Warrier, Katie White, Alan C Geller
BACKGROUND: Given the rising rates of obesity there is a pressing need for medical schools to better prepare students for intervening with patients who have overweight or obesity and for prevention efforts. OBJECTIVE: To assess the effect of a multi-modal weight management curriculum on counseling skills for health behavior change. DESIGN: A pair-matched, group-randomized controlled trial (2015-2020) included students enrolled in eight U.S...
April 9, 2021: Journal of General Internal Medicine
Johanna Strempfl, Teresa Wutzl, Didem Ün, Susanne Greber-Platzer, Mohammad Keilani, Richard Crevenna, Alexandra Thajer
BACKGROUND: This study determined to what extent the underpinning of physiotherapeutic interventions with the evidence-based motivational psychological concept of the self-determination theory (SDT) by Ryan and Deci can increase motivation and enjoyment of movement in obese adolescents. METHODS: In this study 12 obese adolescents aged 14-18 years were offered a targeted group-specific sports program including a home exercise program of 8 weeks. The group leaders were trained in the SDT and supported to integrate motivational aspects...
April 9, 2021: Wiener Klinische Wochenschrift
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