keyword
https://read.qxmd.com/read/37264984/balloon-dilation-eustachian-tuboplasty-for-dilatory-dysfunction-with-and-without-effusion-a-comprehensive-outcome-analysis
#41
JOURNAL ARTICLE
Jung-Ting Lin, Heng-Jui Hsu, Chen-Yu Ho, Shu-Wei Tsai, Yi-Lu Li, Jiunn-Liang Wu
OBJECTIVE: This study aimed (1) to demonstrate the efficacy of balloon dilation Eustachian tuboplasty (BDET) for dilatory Eustachian tube dysfunction (ETD) and (2) to determine whether adjunctive ventilation tube insertion (VTI) is superior to myringotomy in relieving symptoms for patients with ETD and concurrent middle ear effusion (MEE) treated with BDET. STUDY DESIGN: A retrospective cohort study. SETTING: Tertiary care academic center...
June 2, 2023: Otolaryngology—Head and Neck Surgery
https://read.qxmd.com/read/37257730/functional-and-structural-impact-of-10-acadm-missense-mutations-on-human-medium-chain-acyl-coa-dehydrogenase
#42
JOURNAL ARTICLE
Catarina A Madeira, Carolina Anselmo, João M Costa, Cátia A Bonito, Ricardo J Ferreira, Daniel J V A Santos, Ronald Wanders, João B Vicente, Fátima V Ventura, Paula Leandro
Medium chain acyl-CoA dehydrogenase (MCAD) deficiency (MCADD) is associated with ACADM gene mutations, leading to an impaired function and/or structure of MCAD. Importantly, after import into the mitochondria, MCAD must incorporate a molecule of flavin adenine dinucleotide (FAD) per subunit and assemble into tetramers. However, the effect of MCAD amino acid substitutions on FAD incorporation has not been investigated. Herein, the commonest MCAD variant (p.K304E) and 11 additional rare variants (p.Y48C, p.R55G, p...
May 29, 2023: Biochimica et Biophysica Acta. Molecular Basis of Disease
https://read.qxmd.com/read/37251827/housing-market-forecasts-via-stock-market-indicators
#43
JOURNAL ARTICLE
Varun Mittal, Laura P Schaposnik
Through the reinterpretation of housing data as candlesticks, we extend Nature Scientific Reports article by Liang and Unwin [LU22] on stock market indicators for COVID-19 data, and utilize some of the most prominent technical indicators from the stock market to estimate future changes in the housing market, comparing the findings to those one would obtain from studying real estate ETF's. By providing an analysis of MACD, RSI, and Candlestick indicators (Bullish Engulfing, Bearish Engulfing, Hanging Man, and Hammer), we exhibit their statistical significance in making predictions for USA data sets (using Zillow Housing data) and also consider their applications within three different scenarios: a stable housing market, a volatile housing market, and a saturated market...
May 2023: Heliyon
https://read.qxmd.com/read/37167329/using-heatmap-visualization-to-assess-the-performance-of-the-dj30-and-nasdaq100-indices-under-diverse-vma-trading-rules
#44
JOURNAL ARTICLE
Yuhsin Chen, Paoyu Huang, Min-Yuh Day, Yensen Ni, Mei-Chu Liang
We investigate whether using various VMA trading rules would improve investment performance due to the flexibility of VMA trading rules and the aid of Heatmap Visualization. Previously, investors frequently chose the best performance derived from limited VMA trading rules. However, our new design, which can display all results using Heatmap Visualization, shows that the NASDAQ100 index outperforms the DJ30 index and that weekly data outperforms daily data when measured by annualized return. These findings may be useful to those who trade index ETFs tracking the DJ30 and NASDAQ100 indices, as well as investors making investment decisions, and may contribute to the existing literature by evaluating the outcomes of VMA trading rules and providing insights for index ETF investors using a heatmap matrix, which is rarely explored and presented in the relevant literature...
2023: PloS One
https://read.qxmd.com/read/37167314/actual-evapotranspiration-by-machine-learning-and-remote-sensing-without-the-thermal-spectrum
#45
JOURNAL ARTICLE
Taiara Souza Costa, Roberto Filgueiras, Robson Argolo Dos Santos, Fernando França da Cunha
The objectives of this study were to use machine learning algorithms to establish a model for estimating the evapotranspiration fraction (ETf) using two data input scenarios from the spectral information of the Sentinel-2 constellation, and to analyze the temporal and spatial applicability of the models to estimate the actual evapotranspiration (ETr) in agricultural crops irrigated by center pivots. The spectral bands of Sentinel 2A and 2B satellite and vegetation indices formed the first scenario. The second scenario was formed by performing the normalized ratio procedure between bands (NRPB) and joining the variables applied in the first scenario...
2023: PloS One
https://read.qxmd.com/read/37163169/covid-induced-sentiment-and-the-intraday-volatility-spillovers-between-energy-and-other-etfs
#46
JOURNAL ARTICLE
Muhammad Abubakr Naeem, Sitara Karim, Larisa Yarovaya, Brian M Lucey
Did Covid19 induce market turmoil impact the intraday volatility spillovers between energy and other ETFs?. To examine this, we first estimate the realized volatility of ETFs using the 5-min high-frequency data. Next, we employ time-varying parameter vector autoregressions (TVP-VAR). Finally, we utilize the wavelet coherence measure to test the time-frequency impact of COVID-induced sentiment on the spillovers by employing investors' psychological and behavioural factors. We find that oil and stock markets are net transmitters while currency, bonds, and silver markets are net receivers...
June 2023: Energy economics
https://read.qxmd.com/read/37119850/non-covalent-interactions-that-tune-the-reactivities-of-the-flavins-in-bifurcating-electron-transferring-flavoprotein
#47
JOURNAL ARTICLE
María González-Viegas, Rajiv K Kar, Anne-Frances Miller, Maria-Andrea Mroginski
Bifurcating electron transferring flavoproteins (Bf-ETFs) tune chemically identical flavins to two contrasting roles. To understand how, we used hybrid quantum mechanical molecular mechanical calculations to characterize non-covalent interactions applied to each flavin by the protein. Our computations replicated the differences between the reactivities of the flavins: the electron transferring flavin (ET flavin) was calculated to stabilize anionic semiquinone (ASQ) as needed to execute its single-electron transfers, whereas the Bf flavin (Bf flavin) was found to disfavor the ASQ state more than does free flavin and to be less susceptible to reduction...
April 27, 2023: Journal of Biological Chemistry
https://read.qxmd.com/read/37086514/the-role-of-etfs-amino-acids-on-the-stability-and-inhibition-of-p53-mdm2-complex-of-anticancer-p53-derivatives-peptides-density-functional-theory-and-molecular-docking-studies
#48
JOURNAL ARTICLE
Catalina Soriano-Correa, Micheel Merari Vichi-Ramírez, Edtson E Herrera-Valencia, Carolina Barrientos-Salcedo
Cancer is one of the leading causes of mortality in the world. Despite the existence of diverse antineoplastic treatments, these do not possess the expected efficacy in many cases. Knowledge of the molecular mechanisms involved in tumor processes allows the identification of a greater number of therapeutic targets employed in the study of new anticancer drugs. In the last decades, peptide-based therapy design using computational chemistry has gained importance in the field of oncology therapeutics. This work aims to evaluate the electronic structure, physicochemical properties, stability, and inhibition of ETFS amino acids and peptides derived from the p53-MDM2 binding domain with action in cancer cells; by means of chemical descriptors at the DFT-BHandHLYP level in an aqueous solution, and its intermolecular interactions through molecular docking studies...
April 13, 2023: Journal of Molecular Graphics & Modelling
https://read.qxmd.com/read/37075025/dissecting-eustachian-tube-dysfunction-from-phenotypes-to-endotypes
#49
JOURNAL ARTICLE
Cuneyt M Alper, Miriam S Teixeira, Ellen M Mandel, J Douglas Swarts
OBJECTIVE: A broad spectrum of complaints, symptoms and manifestations has been assigned to Eustachian tube (ET) dysfunction (ETD). While such presentations may manifest as ETD phenotypes, underlying mechanisms are defined as endotypes. Our goal is to develop a diagnostic approach to differentiate the endotypes and guide clinicians in the workup and selection of treatments targeting the mechanism of ETD. STUDY DESIGN: Retrospective. SETTING: Tertiary care...
2023: PloS One
https://read.qxmd.com/read/36996550/time-varying-price-dynamics-of-clean-and-dirty-energy-portfolios
#50
JOURNAL ARTICLE
Abdollah Ah Mand, Abdul Ghafoor, Imtiaz Sifat
This paper investigates the dynamic relationships between four key instruments related to clean and dirty energy assets: WTI futures, United States Oil Fund (USO), EnergySelect Sector SPDR Fund (XLE), and iShares Global Clean Energy ETF (ICLN). Econometric tests confirm a long-term relationship between all variables, with causality tests showing that clean energy ETF has a causal influence on most instruments. However, the causal patterns are not definitively interpretable in an economic framework. Moreover, using wavelet-based tests on a 1-min interval transaction dataset, we further find convergence delay between WTI and XLE, and to a lesser extent, USO, but not ICLN...
March 28, 2023: Journal of Environmental Management
https://read.qxmd.com/read/36975374/microscopic-determination-of-the-local-hydration-number-of-polymer-electrolyte-membranes-using-sans-partial-scattering-function-analysis
#51
JOURNAL ARTICLE
Yue Zhao, Kimio Yoshimura, Shinichi Sawada, Akihiro Hiroki, Aurel Radulescu, Yasunari Maekawa
The conventional hydration number, λ, of a polymer electrolyte membrane (PEM) is estimated by the gravimetric measurement of the total water uptake in the membrane. This is the overall water molecules divided by the number of ionic groups covering the water distribution from the macroscale to the molecular level. For a more precise evaluation of the local ion-water interactions and ion transport efficiency in hydrophilic channels, in contrast to λ, we here propose an index, local hydration number (λlocal ), defined as the number of water molecules located adjacent to and interacting with ionic groups in a PEM, per ionic group in the hydrophilic channels...
March 28, 2023: ACS Macro Letters
https://read.qxmd.com/read/36962060/prospective-validation-of-tubomanometry-in-children-with-normal-eustachian-tube-function
#52
JOURNAL ARTICLE
Götz Kuhlmann, Sabine Schädelin, Nicolas Gürtler
OBJECTIVES: Tubomanometry (TMM), described initially by Estève, is a relatively new manometric method for testing the eustachian tube function (ETF). This study presents the analysis of the measurement of ETF of healthy children by TMM, which has, to date, not been properly evaluated. The objectives of the study were to establish normative data for TMM and to demonstrate TMM as a reliable and valid method for measuring ETF in children. DESIGN: The evaluation, after initial power analysis, comprised 35 children from 6 to 15 years of age with an intact tympanic membrane, no severe ET dysfunction, and less than three inflammations of the middle ear in their medical history...
March 24, 2023: Otology & Neurotology
https://read.qxmd.com/read/36937111/alkaline-stability-of-anion-exchange-membranes
#53
JOURNAL ARTICLE
Sapir Willdorf-Cohen, Avital Zhegur-Khais, Julia Ponce-González, Saja Bsoul-Haj, John R Varcoe, Charles E Diesendruck, Dario R Dekel
Recently, the development of durable anion-exchange membrane fuel cells (AEMFCs) has increased in intensity due to their potential to use low-cost, sustainable components. However, the decomposition of the quaternary ammonium (QA) cationic groups in the anion-exchange membranes (AEMs) during cell operation is still a major challenge. Many different QA types and functionalized polymers have been proposed that achieve high AEM stabilities in strongly alkaline aqueous solutions. We previously developed an ex situ technique to measure AEM alkaline stabilities in an environment that simulates the low-hydration conditions in an operating AEMFC...
January 23, 2023: ACS Applied Energy Materials
https://read.qxmd.com/read/36874272/inhibition-of-ehrlichia-chaffeensis-infection-by-cell-permeable-macrocyclic-peptides-that-bind-type-iv-secretion-effector-etf-1
#54
JOURNAL ARTICLE
Mingqun Lin, Amritendu Koley, Wenqing Zhang, Dehua Pei, Yasuko Rikihisa
Ehrlichia chaffeensis is an obligatory intracellular bacterium that infects monocytes and macrophages, and causes human monocytic ehrlichiosis, an emerging life-threatening infectious disease. Ehrlichia translocated factor-1 (Etf-1), a type IV secretion system effector, is essential for Ehrlichia infection of host cells. Etf-1 translocates to mitochondria to block host apoptosis; furthermore, it can bind Beclin 1 (ATG6) to induce cellular autophagy and localize to E. chaffeensis -inclusion membrane to obtain host-cell cytoplasmic nutrients...
February 2023: PNAS Nexus
https://read.qxmd.com/read/36862018/on-practical-aspects-of-single-entity-electrochemical-measurements-with-hot-microelectrodes
#55
REVIEW
Aliaksei Boika
When a 10s-100s MHz frequency alternating current (ac) waveform is applied to a disk ultramicroelectrode (UME) in an electrochemical cell, one achieves what is known as a hot microelectrode, or a hot UME. The electrical energy generates heat in an electrolyte solution surrounding the electrode, and the heat transfer leads to formation of a hot zone with the size comparable to the electrode diameter. In addition to heating, ac electrokinetic phenomena generated by the waveform include dielectrophoresis (DEP) and electrothermal fluid flow (ETF)...
March 2, 2023: Analytical Chemistry
https://read.qxmd.com/read/36774564/first%C3%A2-report%C3%A2-%C3%A2-flat-peach-fruit-rot%C3%A2-caused%C3%A2-by%C3%A2-fusarium%C3%A2-fujikuroi-in-china
#56
JOURNAL ARTICLE
Ruiqi Liu, Qing Zeng, Tianong Guo, Guo Yang, Xueyuan Han, Yiwei Mo
Flat peach (Prunus persica L. Batsch. var. compressa Bean) is a distinctive peach variety with flat shape. It is well known for its high nutritional value and pleasant flavor, and has become the primary cultivar in Shengzhou city, Zhejiang province, China. In July 2021, we discovered that 8%-10% of flat peach (data gained from a survey of fifteen trees in each orchard) fruits in three orchards (about 2.6 ha) had a fungal disease in Jinting Town, Shengzhou. The infected fruit by this pathogen showed soft, brown, and sunken lesions, accompanied by a sour odor and white mycelia...
February 12, 2023: Plant Disease
https://read.qxmd.com/read/36676912/composite-proton-conducting-membrane-with-enhanced-phosphoric-acid-doping-of-basic-films-radiochemically-grafted-with-binary-vinyl-heterocyclic-monomer-mixtures
#57
JOURNAL ARTICLE
Paveswari Sithambaranathan, Mohamed Mahmoud Nasef, Arshad Ahmad, Amin Abbasi, T M Ting
A composite proton conducting membrane (PCM) was prepared by radiation-induced grafting (RIG) of binary mixtures of 4-vinyl pyridine (4-VP) and 1-vinylimidazole (1-VIm) onto poly(ethylene- co -tetrafluoroethylene) (ETFE) film followed by phosphoric acid (PA) doping. The grafting parameters such as absorbed dose, temperature, monomer concentration, time, and monomer ratio were varied to control the degree of grafting (DG%). The effect of the reactivity ratio of 4-VP and 1-VIm on the composition and degree of monomer unit alternation in the formed graft copolymer was investigated...
January 13, 2023: Membranes
https://read.qxmd.com/read/36673243/the-complexity-behavior-of-big-and-small-trading-orders-in-the-chinese-stock-market
#58
JOURNAL ARTICLE
Yu Zhu, Wen Fang
The Chinese stock market exhibits many characteristics that deviate from the efficient market hypothesis and the trading volume contains a great deal of complexity information that the price cannot reflect. Do small or big orders drive trading volume? We studied the complex behavior of different orders from a microstructure perspective. We used ETF data of the CSI300, SSE50, and CSI500 indices and divided transactions into big and small orders. A multifractal detrended fluctuation analysis (MFDFA) method was used to study persistence...
January 4, 2023: Entropy
https://read.qxmd.com/read/36583736/seasonal-assessment-of-some-potentially-toxic-elements-with-possible-animal-health-risks-in-atriplex-canescens-pursh-nutt
#59
JOURNAL ARTICLE
Bouzid Nedjimi
In the present investigation Br (Bromine), Cr (Chromium) and Pb (Lead) concentrations were assessed employing X-ray florescence spectrometry to evaluate seasonal variation of these elements in the xero-halophyte Atriplex canescens (Pursh) Nutt., a shrub with high pastoral value. The results showed that A. canescens and its surrounding soil have similar accumulation patterns for Br and Pb across seasons, but Cr concentrations in shrubs are higher in spring than other seasons. The seasonal mean contents of trace elements in A...
December 30, 2022: Bulletin of Environmental Contamination and Toxicology
https://read.qxmd.com/read/36577199/evaluation-of-rapid-maxillary-expansion-or-alternating-rapid-maxillary-expansion-and-constriction-on-eustachian-tube-function-with-audiological-tests-a-randomized-clinical-trial
#60
JOURNAL ARTICLE
Zeynep Çoban Büyükbayraktar, Mansur Doğan, Cenk Doruk, Volkan Yüksel Özel
OBJECTIVES: Maxillary expansion improves the hearing function. This trial aimed to examine the effects of Eustachian tube function (ETF) with audiological tests in orthodontic patients who underwent rapid maxillary expansion (RME) or alternate rapid maxillary expansion and constriction (Alt-RAMEC) treatment. METHODS: Forty individuals (mean age = 13.35 years) included in the trial had a healthy eardrum, no history of orthodontic treatment, maxillary constriction, mandibular constriction and were not affected by acute or chronic otitis...
December 22, 2022: International Journal of Pediatric Otorhinolaryngology
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