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JOURNAL ARTICLE
Mathieu Pioche, João A Cunha Neves, Heiko Pohl, Minh Quyen, Raphaelle Grau, Xavier Dray, Clara Yzet, Mikael Mochet, Jeremie Jacques, Timothee Wallenhorst, Jérôme Rivory, Nadege Siret, Anne-Laure Peillet, Jean-Baptiste Chevaux, Francois Mion, Ulriikka Chaput, Philippe Jacob, Daniel Grinberg, Jean-Christophe Saurin, Robin Baddeley, Enrique Rodriguez de Santiago, Pierre-Jean Cottinet
INTRODUCTION: The environmental impact of endoscopy, including small-bowel capsule endoscopy (SBCE), has gained attention due to its contribution to the global carbon footprint. This study aimed to evaluate the greenhouse gas (GHG) emissions (kgCO2e) of SBCE, including devices life cycle and capsule journey. METHODS: SBCE devices (3 brands) were evaluated using life cycle assessment methodology (ISO 14040), including patient travelling, bowel preparation, capsule examination and video recording...
April 24, 2024: Endoscopy
#22
JOURNAL ARTICLE
Long-term mandibular growth in patients with airway obstruction treated with mandibular distraction.
Maria Costanza Meazzini, Alejandro Piza, Novelli Giorgio, Davide Sozzi, Elena de Ponti, Fabio Mazzoleni
Congenital craniofacial malformations play an important role in upper airway obstruction. One of the main causes is mandibular hypoplasia which is present in the pierre robin sequence. Mandibular distraction osteogenesis (MDO) is one of the most commonly used treatments for the resolution of upper airway obstruction in patients that do not respond to a conservative treatment. We performed a long term follow up of syndromic and non-syndromic patients with pierre robin sequence where the lateral xrays were studied before surgery (T1), after MDO (T2) and long-term follow-up (T3, at least 5 years)...
March 31, 2024: Journal of Cranio-maxillo-facial Surgery
#23
REVIEW
Pierre Scheffler, Christian Fung, Shahan Momjian, Dominik Koessinger, Levin Häni, Nicolas Neidert, Jakob Straehle, Florian Volz, Oliver Schnell, Jürgen Beck, Amir El Rahal
OBJECTIVE: Glioblastomas are the most common primary central nervous system (CNS) tumors. Although modern management strategies have modestly improved overall survival, the prognosis remains dismal, with treatment side effects often impinging on the clinical course. Glioblastomas cause neurological dysfunction by infiltrating CNS tissue and via perifocal oedema formation. The administration of steroids such as dexamethasone is thought to alleviate symptoms by reducing oedema. However, despite its widespread use, the evidence for the administration of dexamethasone is limited and conflicting...
April 1, 2024: Cancers
#24
JOURNAL ARTICLE
Agnès Lewden, Chelsea Ward, Aude Noiret, Sandra Avril, Lucie Abolivier, Caroline Gérard, Tracey L Hammer, Émilie Raymond, Jean-Patrice Robin, Vincent A Viblanc, Pierre Bize, Antoine Stier
Assessing the physiological stress responses of wild animals opens a window for understanding how organisms cope with environmental challenges. Since stress response is associated with changes in body temperature, the use of body surface temperature through thermal imaging could help to measure acute and chronic stress responses non-invasively. We used thermal imaging, acute handling-stress protocol and an experimental manipulation of corticosterone (the main glucocorticoid hormone in birds) levels in breeding king penguins (Aptenodytes patagonicus), to assess: 1...
April 10, 2024: Journal of Thermal Biology
#25
JOURNAL ARTICLE
Frederick S Vom Saal, Michael Antoniou, Scott M Belcher, Ake Bergman, Ramji K Bhandari, Linda S Birnbaum, Aly Cohen, Terrence J Collins, Barbara Demeneix, Anne Marie Fine, Jodi A Flaws, Veronique Gayrard, William H Goodson, Andrea C Gore, Jerrold J Heindel, Patricia A Hunt, Taisen Iguchi, Christopher D Kassotis, Andreas Kortenkamp, Robin Mesnage, Jane Muncke, John Peterson Myers, Angel Nadal, Retha R Newbold, Vasantha Padmanabhan, Paola Palanza, Zandra Palma, Stefano Parmigiani, Lyn Patrick, Gail S Prins, Cheryl S Rosenfeld, Niels E Skakkebaek, Carlos Sonnenschein, Ana M Soto, Shanna H Swan, Julia A Taylor, Pierre-Louis Toutain, Frank A von Hippel, Wade V Welshons, Daniel Zalko, R Thomas Zoeller
BACKGROUND: The European Food Safety Authority (EFSA) recommended lowering their estimated tolerable daily intake (TDI) for bisphenol A (BPA) 20,000-fold to <mml:math xmlns:mml="https://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mn>0.2</mml:mn><mml:mtext> ng</mml:mtext><mml:mo>/</mml:mo><mml:mi>kg</mml:mi><mml:mtext> body weight </mml:mtext><mml:mo>(</mml:mo><mml:mtext>BW</mml:mtext><mml:mo>)</mml:mo><mml:mo>/</mml:mo><mml:mtext>day</mml:mtext></mml:mrow></mml:math>...
April 2024: Environmental Health Perspectives
#26
JOURNAL ARTICLE
Tarek Sharshar, Lamiae Grimaldi-Bensouda, Shidasp Siami, Alain Cariou, Abdel Ben Salah, Pierre Kalfon, Romain Sonneville, Nicolas Meunier-Beillard, Jean-Pierre Quenot, Bruno Megarbane, Stephane Gaudry, Haikel Oueslati, Segolene Robin-Lagandre, Carole Schwebel, Aurelien Mazeraud, Djillali Annane, Lionelle Nkam, Diane Friedman
PURPOSE: Critical illness is associated with long-term increased mortality and impaired quality of life (QoL). We assessed whether multidisciplinary consultations would improve outcome at 12 months (M12) after intensive care unit (ICU) discharge. METHODS: We performed an open, multicenter, parallel-group, randomized clinical trial. Eligible are patients discharged alive from ICU in 11 French hospitals between 2012 and 2018. The intervention group had a multidisciplinary face-to-face consultation involving an intensivist, a psychologist, and a social worker at ICU discharge and then at M3 and M6 (optional)...
April 8, 2024: Intensive Care Medicine
#27
JOURNAL ARTICLE
Ariane Bollack, Lyduine E Collij, David Vállez García, Mahnaz Shekari, Daniele Altomare, Pierre Payoux, Bruno Dubois, Oriol Grau-Rivera, Mercè Boada, Marta Marquié, Agneta Nordberg, Zuzana Walker, Philip Scheltens, Michael Schöll, Robin Wolz, Jonathan M Schott, Rossella Gismondi, Andrew Stephens, Christopher Buckley, Giovanni B Frisoni, Bernard Hanseeuw, Pieter Jelle Visser, Rik Vandenberghe, Alexander Drzezga, Maqsood Yaqub, Ronald Boellaard, Juan Domingo Gispert, Pawel Markiewicz, David M Cash, Gill Farrar, Frederik Barkhof
INTRODUCTION: To support clinical trial designs focused on early interventions, our study determined reliable early amyloid-β (Aβ) accumulation based on Centiloids (CL) in pre-dementia populations. METHODS: A total of 1032 participants from the Amyloid Imaging to Prevent Alzheimer's Disease-Prognostic and Natural History Study (AMYPAD-PNHS) and Insight46 who underwent [18 F]flutemetamol, [18 F]florbetaben or [18 F]florbetapir amyloid-PET were included...
April 4, 2024: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
#28
JOURNAL ARTICLE
Pierre-André Jarrot, Adrien Mirouse, Sébastien Ottaviani, Simon Cadiou, Jean-Hugues Salmon, Eric Liozon, Simon Parreau, Martin Michaud, Benjamin Terrier, Pierre-Edouard Gavand, Ludovic Trefond, Virginie Lavoiepierre, Jeremy Keraen, Daniel Rekassa, Bastien Bouldoires, Thierry Weitten, Damien Roche, Antoine Poulet, Caroline Charpin, Vincent Grobost, Marion Hermet, Magali Pallure, Chloe Wackenheim, Ludovic Karkowski, Pierre Grumet, Thomas Rogier, Nabil Belkefi, Vincent Pestre, Emilie Broquet, Amélie Leurs, Sophie Gautier, Valérie Gras, Pierre Gilet, Jan Holubar, Nadia Sivova, Nicolas Schleinitz, Jean-Marc Durand, Brice Castel, Alexandre Petrier, Robin Arcani, Baptiste Gramont, Philippe Guilpain, Hubert Lepidi, Pierre-Jean Weiller, Joelle Micallef, David Saadoun, Gilles Kaplanski
We conducted a national in-depth analysis including pharmacovigilance reports and clinical study to assess the reporting rate (RR) and to determine the clinical profile of polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) in COVID-19-vaccinated individuals. First, based on the French pharmacovigilance database, we estimated the RR of PMR and GCA cases in individuals aged over 50 who developed their initial symptoms within one month of receiving the BNT162b2 mRNA, mRNA-1273, ChAdOx1 nCoV-19, and Ad26...
December 31, 2024: Human Vaccines & Immunotherapeutics
#29
JOURNAL ARTICLE
James Butterfield, Megan Pencek, Keith Sweitzer, Eileen Marrinan, Heidi Connolly, Sara Neimanis, Clinton Morrison
BACKGROUND: Pharyngeal flap (PF) surgery is effective at improving velopharyngeal sufficiency, but historical literature shows a concerning prevalence rate of obstructive sleep apnea (OSA), reported as high as 20%. Our institution has developed a protocol to minimize risk of postoperative obstructive complications and increase safety of PF surgery. We hypothesize that (1) preoperative staged removal of significant adenotonsillar tissue along with (2) multiview videofluoroscopy to guide patient-specific surgical approach via appropriately sized PFs can result in excellent speech outcomes while limiting occurrence of OSA...
April 1, 2024: Annals of Plastic Surgery
#30
JOURNAL ARTICLE
Harrison Theile, Yun Phua, Stuart Bade, Susan O'Mahony, Jasneek Chawla, Sadasivam Suresh, Richard Theile
PURPOSE: Pierre-Robin Sequence (PRS) is a congenital abnormality characterized by micrognathia, glossoptosis, and variable severity upper airway obstruction. Clear management algorithms are lacking, particularly the indications for surgical versus nonsurgical intervention. The authors reviewed the management of these children in Queensland. METHODS: All children diagnosed with PRS at Queensland Children's Hospital from April 2014 to October 2019 were identified (n=45), and their charts were retrospectively reviewed...
March 27, 2024: Journal of Craniofacial Surgery
#31
JOURNAL ARTICLE
Robin Lebas, Benjamin Calvet, Laurence Schadler, Pierre-Marie Preux, Marie-Laure Laroche
BACKGROUND: Particularities in psychiatry care can increase the risk of medication errors (MEs). OBJECTIVE: To analyze the MEs that occurred in a psychiatric hospital and to quantify relationships between the use of certain types of medication and the type of MEs. METHODS: We conducted a retrospective register based cross-sectional study in a French psychiatric hospital (2014-2021). All MEs were analyzed using ALARM method to identify type, stage of occurring and interception (defenses), consequences, drug involved and root causes...
March 20, 2024: Research in Social & Administrative Pharmacy: RSAP
#32
JOURNAL ARTICLE
Michelle Geryk, Robin Canac, Virginie Forest, Pierre Lindenbaum, Aurore Girardeau, Manon Baudic, Estelle Baron, Anne Bibonne, Caroline Chariau, Florence Kyndt, Richard Redon, Jean-Jacques Schott, Jean-Baptiste Gourraud, Julien Barc, Flavien Charpentier
Mutations in the DES gene, which encodes the intermediate filament desmin, lead to desminopathy, a rare disease characterized by skeletal muscle weakness and different forms of cardiomyopathies associated with cardiac conduction defects and arrhythmias. We generated human induced pluripotent stem cells (hiPSC) from a patient carrying the DES p.R406W mutation, and employed CRISPR/Cas9 to rectify the mutation in the patient's hiPSC line and introduced the mutation in an hiPSC line from a control individual unrelated to the patient...
March 21, 2024: Stem Cell Research
#33
JOURNAL ARTICLE
Elias Ayoub, Stessy Kutchukian, Pierre Bigot, Aurélien Dinh, Bastien Gondran-Tellier, Humphrey Robin, Marc Françot, Stéphane de Vergie, Jérôme Rigaud, Mathilde Chapuis, Laurent Brureau, Camille Jousseaume, Omar Karray, Fares T Kosseifi, Shahed Borojeni, Aurélien Descazeaud, Harrison-Junior Asare, Maxime Gaullier, Baptiste Poussot, Thibault Tricard, Michael Baboudjian, Éric Lechevallier, Pierre-Olivier Delpech, Héloïse Ducousso, Simon Bernardeau, Franck Bruyère, Maxime Vallée
INTRODUCTION: In the era of increased bacterial resistance, the main strategy is to reduce the prescription of antibiotics when possible. Nowadays, it is highly recommended to screen for asymptomatic bacteriuria (ABU), prior to urological surgery with potential mucosal breach or urine exposure. Screening and treating urinary colonization is a strategy widely adopted before radical and partial nephrectomy but without any evidence. Our main end point in this study is to analyze the relationship between preoperative urine culture and the risk of postoperative febrile urinary tract infection (UTI) or surgical-site infection (SSI) in partial or radical nephrectomy patients...
March 20, 2024: World Journal of Urology
#34
REVIEW
Peter Lapner, Ujash Sheth, Diane Nam, Emil Schemitsch, Pierre Guy, Robin Richards
We sought to compare outcomes and reoperation rates for the surgical treatment of proximal humerus fractures (excluding head-splitting fractures, fracture-dislocations, and isolated greater-tuberosity fractures) in men and women older than 60 years. We searched MEDLINE, Embase, and Cochrane through to Feb. 1, 2022, and included all English-language randomized trials comparing operative versus nonoperative treatment; open reduction and internal fixation (ORIF) with locking plate versus intramedullary nail; arthroplasty versus ORIF; and reverse shoulder arthroplasty versus hemiarthroplasty...
2024: Canadian Journal of Surgery. Journal Canadien de Chirurgie
#35
JOURNAL ARTICLE
A Cole Burton, Christopher Beirne, Kaitlyn M Gaynor, Catherine Sun, Alys Granados, Maximilian L Allen, Jesse M Alston, Guilherme C Alvarenga, Francisco Samuel Álvarez Calderón, Zachary Amir, Christine Anhalt-Depies, Cara Appel, Stephanny Arroyo-Arce, Guy Balme, Avi Bar-Massada, Daniele Barcelos, Evan Barr, Erika L Barthelmess, Carolina Baruzzi, Sayantani M Basak, Natalie Beenaerts, Jonathan Belmaker, Olgirda Belova, Branko Bezarević, Tori Bird, Daniel A Bogan, Neda Bogdanović, Andy Boyce, Mark Boyce, LaRoy Brandt, Jedediah F Brodie, Jarred Brooke, Jakub W Bubnicki, Francesca Cagnacci, Benjamin Scott Carr, João Carvalho, Jim Casaer, Rok Černe, Ron Chen, Emily Chow, Marcin Churski, Connor Cincotta, Duško Ćirović, T D Coates, Justin Compton, Courtney Coon, Michael V Cove, Anthony P Crupi, Simone Dal Farra, Andrea K Darracq, Miranda Davis, Kimberly Dawe, Valerie De Waele, Esther Descalzo, Tom A Diserens, Jakub Drimaj, Martin Duľa, Susan Ellis-Felege, Caroline Ellison, Alper Ertürk, Jean Fantle-Lepczyk, Jorie Favreau, Mitch Fennell, Pablo Ferreras, Francesco Ferretti, Christian Fiderer, Laura Finnegan, Jason T Fisher, M Caitlin Fisher-Reid, Elizabeth A Flaherty, Urša Fležar, Jiří Flousek, Jennifer M Foca, Adam Ford, Barbara Franzetti, Sandra Frey, Sarah Fritts, Šárka Frýbová, Brett Furnas, Brian Gerber, Hayley M Geyle, Diego G Giménez, Anthony J Giordano, Tomislav Gomercic, Matthew E Gompper, Diogo Maia Gräbin, Morgan Gray, Austin Green, Robert Hagen, Robert Bob Hagen, Steven Hammerich, Catharine Hanekom, Christopher Hansen, Steven Hasstedt, Mark Hebblewhite, Marco Heurich, Tim R Hofmeester, Tru Hubbard, David Jachowski, Patrick A Jansen, Kodi Jo Jaspers, Alex Jensen, Mark Jordan, Mariane C Kaizer, Marcella J Kelly, Michel T Kohl, Stephanie Kramer-Schadt, Miha Krofel, Andrea Krug, Kellie M Kuhn, Dries P J Kuijper, Erin K Kuprewicz, Josip Kusak, Miroslav Kutal, Diana J R Lafferty, Summer LaRose, Marcus Lashley, Richard Lathrop, Thomas E Lee, Christopher Lepczyk, Damon B Lesmeister, Alain Licoppe, Marco Linnell, Jan Loch, Robert Long, Robert C Lonsinger, Julie Louvrier, Matthew Scott Luskin, Paula MacKay, Sean Maher, Benoît Manet, Gareth K H Mann, Andrew J Marshall, David Mason, Zara McDonald, Tracy McKay, William J McShea, Matt Mechler, Claude Miaud, Joshua J Millspaugh, Claudio M Monteza-Moreno, Dario Moreira-Arce, Kayleigh Mullen, Christopher Nagy, Robin Naidoo, Itai Namir, Carrie Nelson, Brian O'Neill, M Teague O'Mara, Valentina Oberosler, Christian Osorio, Federico Ossi, Pablo Palencia, Kimberly Pearson, Luca Pedrotti, Charles E Pekins, Mary Pendergast, Fernando F Pinho, Radim Plhal, Xochilt Pocasangre-Orellana, Melissa Price, Michael Procko, Mike D Proctor, Emiliano Esterci Ramalho, Nathan Ranc, Slaven Reljic, Katie Remine, Michael Rentz, Ronald Revord, Rafael Reyna-Hurtado, Derek Risch, Euan G Ritchie, Andrea Romero, Christopher Rota, Francesco Rovero, Helen Rowe, Christian Rutz, Marco Salvatori, Derek Sandow, Christopher M Schalk, Jenna Scherger, Jan Schipper, Daniel G Scognamillo, Çağan H Şekercioğlu, Paola Semenzato, Jennifer Sevin, Hila Shamon, Catherine Shier, Eduardo A Silva-Rodríguez, Magda Sindicic, Lucy K Smyth, Anil Soyumert, Tiffany Sprague, Colleen Cassady St Clair, Jennifer Stenglein, Philip A Stephens, Kinga Magdalena Stępniak, Michael Stevens, Cassondra Stevenson, Bálint Ternyik, Ian Thomson, Rita T Torres, Joan Tremblay, Tomas Urrutia, Jean-Pierre Vacher, Darcy Visscher, Stephen L Webb, Julian Weber, Katherine C B Weiss, Laura S Whipple, Christopher A Whittier, Jesse Whittington, Izabela Wierzbowska, Martin Wikelski, Jacque Williamson, Christopher C Wilmers, Todd Windle, Heiko U Wittmer, Yuri Zharikov, Adam Zorn, Roland Kays
Wildlife must adapt to human presence to survive in the Anthropocene, so it is critical to understand species responses to humans in different contexts. We used camera trapping as a lens to view mammal responses to changes in human activity during the COVID-19 pandemic. Across 163 species sampled in 102 projects around the world, changes in the amount and timing of animal activity varied widely. Under higher human activity, mammals were less active in undeveloped areas but unexpectedly more active in developed areas while exhibiting greater nocturnality...
March 18, 2024: Nature Ecology & Evolution
#36
JOURNAL ARTICLE
Robin Colenbier, Lenny Coppens, Tine Logghe, Eke van Zwol, Jean-Pierre Timmermans, Johannes Bogers
The chorioallantoic membrane (CAM) model is an increasingly attractive model for the study of human tumors. However, concise techniques for the use of pancreatic ductal adenocarcinoma BxPC-3 xenografts in CAM assays are not yet available. Here, we present a protocol for the induction of BxPC-3 xenograft tumors with high grafting efficiency. We describe steps for embryo incubation, egg handling, and grafting, each of which has been optimized to prevent fungal contamination and minimize mortality.
March 15, 2024: STAR protocols
#37
JOURNAL ARTICLE
Jessica L Williams, Kari M Lien, Richard Kirschner, Gregory Allen, Kathy Chapman
OBJECTIVES: Compare the feeding management practices in infants with cleft palate with and without Pierre Robin sequence (PRS) and determine if specific feeding difficulties or interventions predict delayed palate repair. DESIGN: Retrospective cross-sectional study. SETTING: Seventeen cleft palate teams contributed data. PATIENTS: 414 infants were included in this study: 268 infants with cleft palate only and 146 infants with cleft palate and PRS...
March 15, 2024: Cleft Palate-craniofacial Journal
#38
JOURNAL ARTICLE
Pierre-Guillaume Piriou, Julien Plessis, Thibaut Manigold, Vincent Letocart, Robin Le Ruz, Paul Padovani, Patrice Guérin
PURPOSE: Pre-stenting of the right ventricular outflow tract (RVOT) is commonly performed before percutaneous pulmonary valve implantation (PPVI), to relieve obstruction, prevent valved stent fractures, and provide a landing zone. This study aimed to evaluate the biomechanical characteristics of the stents currently used to perform pre-stenting of the RVOT. METHODS: We assessed five commercially available stents: Cheatham-Platinum Stent ("CP Stent"), AndraStent XL, AndraStent XXL, Optimus XL, and Optimus XXL...
March 11, 2024: Cardiovascular Engineering and Technology
#39
JOURNAL ARTICLE
Soubia Akhtar, Muhammad Wasif, Yumna Afzal, Iqra Shahab, Rahim Dhanani, Abdul Rauf Shaikh
Pierre Robin Sequence (PRS), a rare congenital disorder, is a triad of micrognathia, glossoptosis, and tongue based airway obstruction (TBSO). It may occur as isolated anomaly (iPRS) or as a part of a syndrome (sPRS), like that seen in association with Stickler Syndrome. Approximately 20% of children with PRS have congenital heart diseases. To the best of our knowledge this case of a one-day old infant is the first one to be reported as having two heart defects; patent ductus arteriosus and patent foramen ovale in Pierre Robbin Sequence child...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
#40
JOURNAL ARTICLE
Yannick Wilfried Mengue, Pierre-Paul Audate, Jean Dubé, Alexandre Lebel
BACKGROUND: Prevention policies against type 2 diabetes mellitus (T2DM) focus solely on individual healthy lifestyle behaviours, while an increasing body of research recognises the involvement of environmental determinants (ED) (cultural norms of land management and planning, local foodscape, built environment, pollution, and neighbourhood deprivation). Precise knowledge of this relationship is essential to proposing a prevention strategy integrating public health and spatial planning...
March 1, 2024: Systematic Reviews
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