Yue Zheng, Yuchao Wang, Bingcai Qi, Yuheng Lang, Zhibin Zhang, Jie Ma, Minming Lou, Xiaoyu Liang, Yun Chang, Qiang Zhao, Wenqing Gao, Tong Li
BACKGROUND: Differences in border zone contribute to different outcomes post-infarction, such as left ventricular aneurysm (LVA) and myocardial infarction (MI). LVA usually forms within 24 h of the onset of MI and may cause heart rupture; however, LVA surgery is best performed 3 months after MI. Few studies have investigated the LVA model, the differences in border zones between LVA and MI, and the mechanism in the border zone. METHODS: The LVA, MI, and SHAM mouse models were used...
2024: Frontiers in Immunology