Uveitis anterior | Page 9

Muhammet Derda Ozer, Fatih Kebapci, Muhammed Batur, Erbil Seven, Serek Tekin
PURPOSE: To compare corneal endothelial cell density (ECD), iris stromal thickness (IST), iris pigment epithelium optical density (IPE OD), and Schlemm's canal (SC) measurements in patients having unilateral Fuchs' uveitis syndrome (FUS). METHODS: This is a randomized, prospective study. Currently, diagnosed unilateral FUS and phakic cases were defined to be the inclusion criteria to the study. The specular microscope was used to measure ECD. Anterior segment images were acquired by using SD-OCT...
May 18, 2019: Graefe's Archive for Clinical and Experimental Ophthalmology
Gustavo Barreto Melo, Ana Carolina Migliorini Figueira, Fernanda Aparecida Heleno Batista, Acácio Alves Souza Lima Filho, Eduardo Büchele Rodrigues, Rubens Belfort, Maurício Maia
BACKGROUND AND OBJECTIVE: To determine factors causing inflammation after intravitreal aflibercept injections. PATIENTS AND METHODS: This case-control study included aflibercept-treated eyes with inflammation post-injection and aflibercept-treated control eyes. Medical records were analyzed to identify contributing factors. Biophysical tests were performed to characterize properties of particle aggregation. Institutional review board approval was obtained. RESULTS: Inflammation developed in six eyes; three patients had anterior uveitis, and five had vitreous cells...
May 1, 2019: Ophthalmic Surgery, Lasers & Imaging Retina
Shumpei Obata, Yoshitsugu Saishin, Kazuya Teramura, Masahito Ohji
Nivolumab is an anti-programmed cell death protein 1 monoclonal antibody that is used to treat metastatic cutaneous malignant melanoma. Although bilateral uveitis has been reported as a side effect of nivolumab administration, there are few reports of Vogt-Koyanagi-Harada disease (VKH)-like uveitis. We report such a case. A 63-year-old woman with metastatic cutaneous malignant melanoma experienced visual loss in both eyes 10 days after her second nivolumab injection. Her decimal best-corrected visual acuity (BCVA) was 0...
January 2019: Case Reports in Ophthalmology
Rie Tanaka, Toshikatsu Kaburaki, Hisae Nakahara, Keiko Komae
PURPOSE: To investigate the clinical features of patients with ocular inflammation associated with relapsing polychondritis in Japan. METHODS: Ocular findings, systemic symptoms, and therapies were analysed retrospectively. RESULTS: Nine of 11 patients had scleritis (diffuse scleritis: six patients, posterior scleritis: two patients, episcleritis: one patient) and two patients had anterior uveitis. All cases were bilateral, and ten patients experienced recurrent episodes...
May 10, 2019: International Ophthalmology
Noy Ashkenazy, Ujwala S Saboo, Ashley Abraham, Cristiana Ronconi, Jennifer H Cao
PURPOSE: To describe the use of infliximab after adalimumab failure in the treatment of pediatric noninfectious uveitis. METHODS: A retrospective analysis was performed on the medical records of pediatric patients with noninfectious uveitis treated with infliximab for a minimum of 6 months after previously failing to achieve steroid-free remission using adalimumab at the University of Texas Medical School and Children's Medical Center between September 2015 and March 2018...
May 4, 2019: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
Jens Vikse, Svein Joar Auglænd Johnsen, Bjørnar Rønning, Klaus Wildhagen, Kjartan Bryne, Roald Omdal
BACKGROUND: Uveitis and acute renal failure can be seen in various immune-mediated systemic diseases. Here we present a case of a young man with a rare inflammatory oculorenal syndrome. CASE REPORT: A man in his thirties was admitted with a constellation of fatigue, flank pain, weight loss and bilateral acute anterior uveitis. Laboratory tests showed anaemia, leukocytosis with eosinophilia, as well as elevated creatinine and C-reactive protein, and urine analyses demonstrated mild proteinuria...
May 7, 2019: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
Mudit Tyagi, Komal Agarwal, Rajeev R Reddy Pappuru, Chintan Dedhia, Hitesh Agarwal, Sameera Nayak, Bhavik Panchal, Hrishikesh Kaza, Soumyava Basu, Avinash Pathengay, Somasheila Murthy, Virender S Sangwan
AIM: To evaluate clinical presentation, course and outcomes in patients without a history of penetrating ocular trauma who developed Sympathetic Ophthalmia (SO) following vitreoretinal surgeries Methods: Retrospective review of clinical records of all patients diagnosed and treated as S.O was done . All cases without a previous history of trauma were included and were analyzed with respect to clinical presentations, anatomic and visual outcomes. RESULTS: 175 cases of sympathetic ophthalmia were diagnosed and treated till June 2017...
May 5, 2019: Seminars in Ophthalmology
Murat Hasanreisoğlu, Hüseyin Baran Özdemir, Fulya Yaylacıoğlu, Mestan Ertop, Zeynep Aktaş
Relapsing polychondritis is a potentially lethal but rare systemic autoimmune disease. The major site of inflammation is the connective tissue, usually involving the ears, nose, larynx, tracheobronchial tree, and cardiovascular system. Although scleritis and episcleritis are known to be the most probable ocular manifestation, it may also present with uveitis. We present the case of a 22-year-old young lady who initially referred with bilateral red and painful eyes caused by anterior uveitis. Her right ear was also red and painful, consistent with cartilaginous inflammation...
April 30, 2019: Turkish Journal of Ophthalmology
Ameenat Lola Solebo, Jugnoo S Rahi, Andrew D Dick, Athimalaipet V Ramanan, Jane Ashworth, Clive Edelsten
BACKGROUND/AIMS: There is a paucity of high-level evidence to support the management of childhood uveitis, particularly for those children without juvenile idiopathic arthritis uveitis (JIA). We undertook a modified Delphi consensus exercise to identify agreement in the management of chronic anterior uveitis (CAU), the most common manifestation of childhood disease. METHODS: A four-round, two-panel process was undertaken between June and December 2017. Paediatric uveitis specialists identified through multiple sources, including a multicentre network (the Paediatric Ocular Inflammation Group), were invited to participate...
May 2, 2019: British Journal of Ophthalmology
Avni P Finn, Henry L Feng, Terry Kim, Tamer H Mahmoud
PURPOSE: To assess outcomes and complication rates in patients undergoing pars plana vitrectomy (PPV) and implantation of an anterior chamber intraocular lens (ACIOL). DESIGN: Retrospective chart review. PARTICIPANTS: A total of 50 eyes that underwent secondary ACIOL placement in the setting of concurrent PPV from October 2000 to August 2016 were included. METHODS: A retrospective chart review was conducted. MAIN OUTCOME MEASURES: The primary outcome measure was the occurrence of postoperative complication including persistently elevated intraocular pressure, persistent or recurrent hyphema, persistent or recurrent vitreous hemorrhage, persistent corneal edema, or persistent uveitis, macular edema, epiretinal membrane, lens dislocation, retinal tear, or retinal detachment...
September 2018: Ophthalmology retina
Ashley M Cooper, Tokunbo S Obajolowo, Erin D Stahl
Chronic recurrent multifocal osteomyelitis (CRMO) has rarely been associated with uveitis. The authors report a case of new CRMO in a 15-year-old boy with HLA-B27 positive chronic anterior uveitis controlled with methotrexate. This case highlights a potential association between chronic uveitis and CRMO. [J Pediatr Ophthalmol Strabismus. 2019;56:e38-e40.].
April 29, 2019: Journal of Pediatric Ophthalmology and Strabismus
Keegan Mechels, Eric Habbe, Geoffrey Tufty
We report a case of bilateral papillitis and anterior uveitis in a pediatric patient with preceding viral prodrome. Because this is a rare disease in the pediatric population, work-up in this case was extensive given the wide differential of papilledema in the pediatric setting. The clinical significance of this case is to bring to light the timely recognition, follow-up, and treatment of this disease to minimize the burden to the patient and family.
March 2019: South Dakota Medicine: the Journal of the South Dakota State Medical Association
Lucy C Crawford, Justine R Smith
No abstract text is available yet for this article.
April 2019: Clinical & Experimental Ophthalmology
Masaaki Yoshida, Hiroshi Kunikata, Toru Nakazawa
PURPOSE: To report a unique case of nivolumab-induced uveitis and the results of a cytokine analysis of an intraocular fluid sample. CASE REPORT: A 61-year-old male patient undergoing treatment for renal cell carcinoma with nivolumab presented with bilateral uveitis. Severe anterior uveitis and vitreous opacity coincided with decreased visual acuity only in his left eye. Iris damage was present in this eye because of previous complicated cataract surgery. Vitrectomy was performed to remove the vitreous opacity, and visual acuity recovered postoperatively...
April 23, 2019: Ocular Immunology and Inflammation
F López-Herrero, T Rueda-Rueda, B Lechón-Caballero, J L Sánchez-Vicente
No abstract text is available yet for this article.
April 17, 2019: Archivos de la Sociedad Española de Oftalmología
Gholamreza Askari, Amir Reza Moravejolahkami
BACKGROUND To relieve the signs and symptoms of anterior uveitis (AU), an ocular manifestation of Behcet's syndrome, we prescribed a synbiotic supplementation (probiotics and prebiotics) for a 49-year-old woman. CASE REPORT Seven strains of bacteria - Lactobacillus casei, Lactobacillus rhamnosus, Streptococcus thermophilus, Bifidobacterium breve, Lactobacillus acidophilus, Bifidobacterium longum, and Lactobacillus bulgaricus, each 10⁸ colony-forming units (CFU) - and fructo-oligosaccharide (FOS; 100 mg) were given as a capsule 2 times per day...
April 19, 2019: American Journal of Case Reports
Timothy Hamann, Mayss Al-Sheikh, Sandrine Zweifel, Fabio Meier, Daniel Barthelmes, Christian Böni
PURPOSE: The spectrum of intraocular and systemic findings in patients with ocular syphilis is described. Persistent visual dysfunction and structural abnormality, in spite of targeted antibiotic therapy, were identified and analysed. METHODS: Patients with ocular syphilis who were treated at University Hospital Zurich (USZ) between 2010 and 2018 were included in this study. General characteristics, ocular manifestation and visual function (best-corrected visual acuity [BCVA], visual field) before and after treatment were analysed retrospectively...
April 2019: Klinische Monatsblätter Für Augenheilkunde
Lin Yang, Yiguo Qiu, Jingyang Liu, Ru Lin, Peng Yu, Xinyu Fu, Bingtao Hao, Bo Lei
Purpose: To investigate retinal gene expression of tetramethylpyrazine (TMP) eye drop-treated endotoxin-induced uveitis (EIU) in mice and to explore the mechanisms. Methods: The inflammatory signs of the anterior segment were evaluated, and clinical scores were graded. The retinal transcriptome from the TMP eye drop-treated and the untreated mice was identified by RNA sequencing (RNA-seq) strategy. Differentially expressed genes (DEGs) were validated by real-time PCR. The protein-protein interaction was analyzed using the STRING software...
April 17, 2019: Journal of Ocular Pharmacology and Therapeutics
B Jayakrishnan, Saif M Al-Mubaihsi, Masoud S Kashoub, Jojy George
The coexistence of cystic fibrosis (CF) and sarcoidosis is rare. We report a 22-year-old male cystic fibrosis patient who presented multiple times to the Sultan Qaboos University Hospital, Muscat, Oman, in 2013. He was diagnosed with non-parathyroid-related hypercalcaemia and anterior uveitis, while computed tomography revealed mediastinal and abdominal lymphadenopathy and mild hepatosplenomegaly. These findings, in addition to the presence of calciuria and a high angiotensin-converting enzyme (ACE) level, confirmed a clinical diagnosis of sarcoidosis...
November 2018: Sultan Qaboos University Medical Journal
Junko Yasumura, Masato Yashiro, Nami Okamoto, Kosuke Shabana, Hiroaki Umebayashi, Naomi Iwata, Yuka Okura, Tomohiro Kubota, Masaki Shimizu, Minako Tomiita, Yasuo Nakagishi, Kenichi Nishimura, Ryoki Hara, Mao Mizuta, Takahiro Yasumi, Fumiya Yamaide, Hiroyuki Wakiguchi, Masao Kobayashi, Masaaki Mori
BACKGROUND: Although there are many reports on Juvenile Idiopathic arthritis-associated uveitis (JIA-U) from various countries, especially from Europe and North America, there are few reports from Asia. Our aim was to investigate the epidemiology, characteristics and predictors of JIA-U in Japan. METHODS: Data were retrospectively collected on 726 patients with JIA from medical records as of April 2016 at 15 medical centers specialized in pediatric rheumatic diseases...
April 11, 2019: Pediatric Rheumatology Online Journal
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