Dandan Chen, Huaping Sun, David O Warner, Alex Macario
STUDY OBJECTIVE: To describe how the introduction of an Objective Structured Clinical Examination (OSCE) by the American Board of Anesthesiology (ABA) to its initial certification impacted anesthesiology residencies in the United States. DESIGN AND SETTING: A sequential mixed-methods design with focus groups and online survey among program directors of Accreditation Council for Graduate Medical Education-accredited anesthesiology residencies. PATIENTS: No patients were included...
July 20, 2021: Journal of Clinical Anesthesia
Greg J Marchand, Kelly Ware, Ahmed Taher Masoud, Alexa King, Stacy Ruther, Giovanna Brazil, Kaitlynne Cieminski, Nicolas Calteux, Catherine Coriell, Hollie Ulibarri, Julia Parise, Amanda Arroyo, Diana Chen, Maria Pierson, Rasa Rafie, Katelyn Sainz
OBJECTIVE: To review all high quality available evidence regarding the effect of intraoperative bupivacaine 24 hours (or 8.9 half-lives) after intraoperative administration at time of gynaecologic surgery and to ascertain whether a second mechanism of action, beyond the initial prevention of sodium channel depolarization and blockade of nerve impulses, may be occurring. DATA SOURCES: We searched all major databases with an algorithm designed to include all randomized trials that used any form of local bupivacaine, regardless of dose or route of administration, at the time of any gynaecologic surgery and compared its use with saline placebo...
July 19, 2021: Journal of Obstetrics and Gynaecology Canada: JOGC
Tomokazu Tsurugizawa, Daisuke Yoshimaru
A few studies have compared the static functional connectivity between awake and lightly anesthetized states in rodents by resting-state fMRI. However, impact of light anesthesia on static and dynamic fluctuations in functional connectivity has not been fully understood. Here, we developed a resting-state fMRI protocol to perform awake and anesthetized functional MRI in the same mice. Static functional connectivity showed a widespread decrease under light anesthesia, such as when under isoflurane or a mixture of isoflurane and medetomidine...
July 19, 2021: NeuroImage
Masayuki Oshima, Kazuyoshi Aoyama
BACKGROUND: The study purpose was to determine the safety and efficacy of different doses of epidural fentanyl plus local anesthetics on ambulation for patients who had elective cesarean delivery. METHODS: A prospective study at a single community hospital used posturography to compute Sway area for assessment of standing stability [ISRCTN14517337]. Continuous epidural infusion of 0.2% ropivacaine containing either 2.5 mcg.mL-1 (Group 1, n = 8) or 5 mcg...
July 19, 2021: Brazilian Journal of Anesthesiology
Myron Yaster, Sean H Flack, Lynn D Martin, Philip G Morgan
Dr. Anne Marie Lynn (1949 -present), Professor Emeritus of Anesthesiology, Pain Medicine, and Pediatrics at the University of Washington, Seattle was one of the most influential women in pediatric anesthesiology of her generation. Dr. Lynn embodies the spirit of discovery and advancement that have created the practice of pediatric anesthesiology as we know it today. A pioneer in pain medicine pharmacology, particularly morphine and ketorolac, her research transformed pediatric anesthesia, pediatric pain medicine, and pediatric intensive care medicine...
July 22, 2021: Paediatric Anaesthesia
Ho Bum Cho, Mun Gyu Kim, Sun Young Park, Sanghoon Song, Youn Sil Jang, Suyeon Park, Hyun Keun Lee, Jae Hwa Yoo, Ji Won Chung, Sang Ho Kim
BACKGROUND: To determine whether the anesthetic method of propofol total intravenous anesthesia (TIVA) is associated with postoperative outcome in ESRD patients, we evaluated the incidence of postoperative major adverse cardiac events (MACE), comparing propofol TIVA versus anesthesia with volatile anesthesia in ESRD patients. METHODS: Retrospectively, we identified cases with ESRD patients who underwent surgery under general anesthesia. Patients were divided into those who received only volatile anesthesia (volatile group) and those who received only propofol TIVA (TIVA group)...
2021: PloS One
Nicholas West, Matthias Görges, Andrew Poznikoff, Simon Whyte, Stephan Malherbe
BACKGROUND: Dexmedetomidine is a useful anesthetic adjunct, increasingly popular during pediatric surgery and procedural sedation. Its half-life of 2-3 hours might prolong recovery and discharge times when compared with an un-supplemented propofol anesthetic. This may create an additional burden in a busy post-anesthetic care unit (PACU). AIM: To investigate whether intraoperative adjuvant dexmedetomidine delays PACU discharge in patients undergoing propofol anesthesia for day surgery or procedural investigations with minimal anticipated post-procedural pain...
July 22, 2021: Paediatric Anaesthesia
Ferda Yilmaz Inal, Yadigar Yilmaz Camgoz, Hayrettin Daskaya, Hasan Kocoglu
INTRODUCTION: The present study investigates how preoperative anxiety and pain sensitivity affect the consumption of anesthetics, time elapsed until the desired sedation level is achieved, preoperative hemodynamics, postoperative recovery time, and postoperative pain. METHODS: The present study includes 80 ASA 1-2 patients aged between 20 and 65 who were scheduled for endoscopic ultrasonography (EUS) under sedation. Patients were instructed to fill out the Spielberger State-Trait Anxiety Inventory (STAI) and Pain Sensitivity Questionnaire (PSQ) before the procedure...
July 22, 2021: Pain and Therapy
Franchesca Rivera-Calonje, Shiu-Yi Emily Chen, Carl Lo, Sang Le, Makoto Nagoshi
BACKGROUND: We present a case of COVID-19-positive pediatric patient for urgent urological surgery by spinal anesthesia to avoid aerosolizing procedure. CASE PRESENTATION: A 12-year-old, COVID-19-positive boy presented for urgent wound incision and drainage at the circumcision site. Our anesthetic plan consisted of spinal anesthesia with sedation. He was transported from the COVID-19 isolation floor to the negative pressure operating room. He was placed in lateral decubitus position and oxygen was delivered through facemask...
July 22, 2021: JA Clinical Reports
H Peuchot, R Khakha, V Riera, M Ollivier, J-N Argenson
INTRODUCTION: The effect of patient anxiety during the perioperative period has been shown to be of great importance in its influence on post-operative recovery. Over the last 10 years, virtual reality (VR) has been developed in anesthesia for patient's distraction by immersion. The aim of this study was to evaluate post-operative patient anxiety the day after TKA surgery under spinal anesthesia (SA) with or without VR distraction. MATERIALS AND METHODS: A single-center, prospective cohort study was performed looking at patients undergoing TKA surgery under SA with a VR headset (group 1) compared with those undergoing the same procedure with standard protocol (group 2)...
July 22, 2021: Archives of Orthopaedic and Trauma Surgery
Sebastian Bergrath, Tobias Strapatsas, Michael Tuemen, Thorsten Reith, Marc Deussen, Olaf Aretz, Andreas Hohn, Andreas Lahm
BACKGROUND: With the coronavirus disease 2019 (COVID-19) outbreak hospitals prepared for increasing numbers of patients without knowing how patient populations were evolving and what resources would be required. The present study aimed to analyze the impact of the local COVID-19 pandemic on emergency resources of all hospitals in a major urban center (Mönchengladbach) in Germany. METHODS: This observational multicenter study involved all acute care hospitals (n = 4)...
July 22, 2021: Der Anaesthesist
Anne-Catherine Schuepfer, Guido Schuepfer, Jacqueline Mauch
Tunnelled hemodialysis catheters are well accepted and widely used devices to provide vascular access for dialysis in patients when an arteriovenous shunt is not feasible or dysfunctional. In the literature complications after implantation are well documented but fatal or near-fatal events during implantation are seldom reported. In this article 3 such cases from a single tertiary center over a period of more than 10 years are presented and discussed. The (near) fatal complications occurred despite experienced surgeons and the use of ultrasound and fluoroscopy during implantation...
July 22, 2021: Der Anaesthesist
Michael Dinsmore, Lashmi Venkatraghavan
PURPOSE OF REVIEW: Deep brain stimulation (DBS) is a rapidly expanding surgical modality for the treatment of patients with movement disorders. Its ability to be adjusted, titrated, and optimized over time has given it a significant advantage over traditional more invasive surgical procedures. Therefore, the success and popularity of this procedure have led to the discovery of new indications and therapeutic targets as well as advances in surgical techniques. The aim of this review is to highlight the important updates in DBS surgery and to exam the anesthesiologist's role in providing optimal clinical management...
July 20, 2021: Current Opinion in Anaesthesiology
Bhiken I Naik, Kai Kuck, Leif Saager, Sachin Kheterpal, Karen B Domino, Karen L Posner, Anik Sinha, Ami Stuart, Chad M Brummett, Marcel E Durieux, Michelle T Vaughn, Nathan L Pace
BACKGROUND: Opioids remain the primary mode of analgesia intraoperatively. There are limited data on how patient, procedural, and institutional characteristics influence intraoperative opioid administration. The aim of this retrospective, longitudinal study from 2012 to 2016 was to assess how intraoperative opioid dosing varies by patient and clinical care factors and across multiple institutions over time. METHODS: Demographic, surgical procedural, anesthetic technique, and intraoperative analgesia data as putative variables of intraoperative opioid utilization were collected from 10 institutions...
July 21, 2021: Anesthesia and Analgesia
Ming-Hua Chen, Chao Fang, Na-Yiyuan Wu, Yu-Hao Xia, You-Jie Zeng, Wen Ouyang
N-methyl-D-aspartate (NMDA) receptors mediate excitatory neurotransmission in the nervous system and are preferentially inhibited by general anesthetics such as sevoflurane. Spontaneous movement is a common complication during sevoflurane anesthesia induction and seriously affects operations. In this study, we investigated the relationship between NMDA polymorphisms and spontaneous movement during sevoflurane induction. This prospective clinical study enrolled 393 patients undergoing sevoflurane anesthesia as part of their surgical routine...
July 21, 2021: Brain and Behavior
Véronique Vitton, Xavier Benoît D'Journo, Martine Reynaud-Gaubert, Marc Barthet, Jean-Michel Gonzalez
BACKGROUND: After lung transplantation (LT), gastroparesis is frequent, occurring in 25% to 63% of cases and leading to pulmonary infections. In refractory disease, classical management has demonstrated limited efficacy. G-POEM is a recently developed safe and effective procedure that has been performed here on 5 patients with severe post-LT gastroparesis. METHODS: In all patients, the diagnosis was confirmed by disturbed gastric emptying scintigraphy and GCSI calculation showing severe disease...
July 21, 2021: Clinical Transplantation
Cetin Akpolat, Selam Yekta Sendul, Ebru Turkoglu Unal, Egemen Karatas, Cemile Ucgul Atilgan, Mehmet Demir
Purpose: To determine the demographic and clinical characteristics of newborn patients who underwent lacrimal probing surgical intervention with or without the marsupialization of intranasal cysts as the primary management for dacryocystocele treatment. Methods: Data from the medical charts of 350 infants who underwent lacrimal probing surgery due to nasolacrimal duct obstruction were reviewed retrospectively. Ten newborn patients with a naive diagnosis of congenital dacryocystocele were included in the study...
January 2021: Therapeutic Advances in Ophthalmology
Haoyue Xu, Hang Liu, Tao Chen, Bo Song, Jin Zhu, Xing Liu, Ming Li, Cong Luo
According to existing reports, mutations in the slow tropomyosin gene ( TPM3 ) may lead to congenital fiber-type disproportion (CFTD), nemaline myopathy (NM) and cap myopathy (CD). They are all congenital myopathies and are associated with clinical, pathological and genetic heterogeneity. A ten-year-old girl with scoliosis was unable to wean from mechanical ventilation after total intravenous anesthesia. The girl has scoliosis, respiratory insufficiency, motion delay and muscle weakness; her younger brother has a similar physiology but does not have scoliosis or respiratory insufficiency, and her parents are healthy...
September 2021: Genes & Diseases
Nadine Corbach, Charlotte Berlier, Mona Lichtblau, Esther I Schwarz, Fiorenza Gautschi, Alexandra Groth, Rolf Schüpbach, Franziska Krähenmann, Stéphanie Saxer, Silvia Ulrich
Introduction: Since pregnancy in women with pulmonary arterial hypertension (PAH) is associated with a high risk of morbidity and mortality, it is recommended that pregnancy should be avoided in PAH. However, some women with mild PAH may consider this recommendation as unsuitable. Unfortunately knowledge on pregnancy outcomes and best management of PAH during pregnancy is limited. Methods: Data from all women with PAH who were followed during pregnancy by a multidisciplinary team at a tertiary referral center for PAH and who delivered between 2004 and 2020 were retrospectively analyzed in a case series...
2021: Frontiers in Medicine
Sujit Jos, S Shankar, Rajeev Anand, Libin Thomas Manathara, Bobby Paulose
Background: Patellar instability is a painful condition which affects the quality of life and mobility of young individuals. The aim of this study is to observe the results of medial patello-femoral ligament reconstruction with hamstring autograft along with a modified Fulkerson osteotomy, for recurrent instability of patella with high-grade trochlear dysplasia in Indian population. Materials & methods: We conducted a prospective observational study of 26 knees (21 patients) who attended our outpatient department from June 2014 to February 2019, with recurrent instability of the patella and high-grade trochlear dysplasia...
September 2021: Journal of Clinical Orthopaedics and Trauma
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