Andrew J Michalak, Adam Greenblatt, Shasha Wu, Steven Tobochnik, Hina Dave, Ramya Raghupathi, Yasar T Esengul, Antonio Guerra, James X Tao, Naoum P Issa, Garth R Cosgrove, Bradley Lega, Peter Warnke, H Isaac Chen, Timothy Lucas, Sameer A Sheth, Garrett P Banks, Churl-Su Kwon, Neil Feldstein, Brett Youngerman, Guy McKhann, Kathryn A Davis, Catherine A Schevon
OBJECTIVE: Stereotactic laser amygdalohippocampotomy (SLAH) is an appealing option for patients with temporal lobe epilepsy, who often require intracranial monitoring to confirm mesial temporal seizure onset. However, given limited spatial sampling, it is possible that stereotactic electroencephalography (stereo-EEG) may miss seizure onset elsewhere. We hypothesized that stereo-EEG seizure onset patterns (SOPs) may differentiate between primary onset and secondary spread and predict postoperative seizure control...
April 4, 2023: Epilepsia