keyword
https://read.qxmd.com/read/38640415/the-expanding-problem-of-regional-adiposity-revisiting-a-1985-diabetes-classic-by-ohlson-et%C3%A2-al
#1
JOURNAL ARTICLE
Olga T Gupta, Rana K Gupta
Body fat distribution is a predictor of metabolic health in obesity. In this Classics in Diabetes article, we revisit a 1985 Diabetes article by Swedish investigators Ohlson et al. This work was one of the first prospective population-based studies that established a relationship between abdominal adiposity and the risk for developing diabetes. Here, we discuss evolving concepts regarding the link between regional adiposity and diabetes and other chronic disorders. Moreover, we highlight fundamental questions that remain unresolved...
May 1, 2024: Diabetes
https://read.qxmd.com/read/38640414/a-comparison-of-daily-glucose-fluctuation-between-gck-mody-and-type-2-diabetes-using-continuous-glucose-monitoring-technology-diabetes-2023-72-812-818
#2
JOURNAL ARTICLE
https://read.qxmd.com/read/38640413/time-in-tight-range-for-patients-with-type-1-diabetes-the-time-is-now-or-is-it-too-soon
#3
EDITORIAL
Vala Hamidi, Jeremy H Pettus
No abstract text is available yet for this article.
May 1, 2024: Diabetes Care
https://read.qxmd.com/read/38640412/werner-syndrome-and-diabetes-opportunities-for-precision-medicine
#4
EDITORIAL
Kerim B Kaylan, Louis H Philipson
No abstract text is available yet for this article.
May 1, 2024: Diabetes Care
https://read.qxmd.com/read/38640411/plant-based-diets-and-diabetes-risk-which-foods-what-mechanisms
#5
EDITORIAL
Dariush Mozaffarian
No abstract text is available yet for this article.
May 1, 2024: Diabetes Care
https://read.qxmd.com/read/38640410/response-to-comment-on-beato-v%C3%A3-bora-et-al-a-multicenter-prospective-evaluation-of-the-benefits-of-two-advanced-hybrid-closed-loop-systems-in-glucose-control-and-patient-reported-outcomes-in-a-real-world-setting-diabetes-care-2024-47-216-224
#6
JOURNAL ARTICLE
Pilar Isabel Beato-Víbora, Ana Chico, Jesus Moreno-Fernandez, Virginia Bellido-Castañeda, Lia Nattero-Chávez, María José Picón-César, María Asunción Martínez-Brocca, Marga Giménez-Álvarez, Eva Aguilera-Hurtado, Elisenda Climent-Biescas, Sharona Azriel-Mira, Ángel Rebollo-Román, Carmen Yoldi-Vergara, Marcos Pazos-Couselo, Nuria Alonso-Carril, Carmen Quirós
No abstract text is available yet for this article.
May 1, 2024: Diabetes Care
https://read.qxmd.com/read/38640409/about-the-artist-abby-gregg
#7
JOURNAL ARTICLE
Benjamin Page
No abstract text is available yet for this article.
May 1, 2024: Diabetes Care
https://read.qxmd.com/read/38640408/about-the-editor-neda-laiteerapong-md-ms-using-economic-modeling-to-improve-access-to-care
#8
JOURNAL ARTICLE
Benjamin Page
No abstract text is available yet for this article.
May 1, 2024: Diabetes Care
https://read.qxmd.com/read/38640407/comment-on-beato-v%C3%A3-bora-et-al-a-multicenter-prospective-evaluation-of-the-benefits-of-two-advanced-hybrid-closed-loop-systems-in-glucose-control-and-patient-reported-outcomes-in-a-real-world-setting-diabetes-care-2024-47-216-224
#9
JOURNAL ARTICLE
https://read.qxmd.com/read/38640337/role-and-molecular-mechanism-of-salvia-miltiorrhiza-associated-with-chemical-compounds-in-the-treatment-of-diabetes-mellitus-and-its-complications-a-review
#10
JOURNAL ARTICLE
Jiajie Li, Jinxing Liu, Weibing Shi, Jinchen Guo
Diabetes mellitus (DM) is one of the most prevalent diseases worldwide, greatly impacting patients' quality of life. This article reviews the progress in Salvia miltiorrhiza, an ancient Chinese plant, for the treatment of DM and its associated complications. Extensive studies have been conducted on the chemical composition and pharmacological effects of S miltiorrhiza, including its anti-inflammatory and antioxidant activities. It has demonstrated potential in preventing and treating diabetes and its consequences by improving peripheral nerve function and increasing retinal thickness in diabetic individuals...
April 19, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38640326/association-of-carpal-tunnel-syndrome-risk-factors-with-treatment-modality-selection-focusing-on-corticosteroid-injection-and-surgery-a-nationwide-population-based-study
#11
JOURNAL ARTICLE
Chang Hyun Doh, Ye-Jee Kim, Jae Kwang Kim, Jongjin Lee, Young Ho Shin
Several studies have revealed the risk factors for carpal tunnel syndrome (CTS). However, no studies have evaluated the influence of these risk factors on the selection of treatment modalities for CTS. This study aimed to determine the influence of CTS risk factors on the selection of CTS treatment modalities with a focus on corticosteroid injection (CI) and surgery. We conducted a retrospective cohort study of patients aged ≥20 years with newly diagnosed CTS in the Korean health insurance review and assessment service between 2010 and 2019...
April 19, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38640314/retrospective-analysis-of-predictive-factors-for-avf-dysfunction-in-patients-undergoing-mhd
#12
JOURNAL ARTICLE
Liqin Wang, Yanna Yang, Qianqian Zhao
To construct an early clinical prediction model for AVF dysfunction in patients undergoing Maintenance Hemodialysis (MHD) and perform internal and external verifications. We retrospectively examined clinical data from 150 patients diagnosed with MHD at Hefei Third People's Hospital from January 2014 to June 2023. Depending on arteriovenous fistula (AVF) functionality, patients were categorized into dysfunctional (n = 62) and functional (n = 88) cohorts. Using the least absolute shrinkage and selection operator(LASSO) regression model, variables potentially influencing AVF functionality were filtered using selected variables that underwent multifactorial logistic regression analysis...
April 19, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38640276/a-review-on-associated-factors-and-management-measures-for-sarcopenia-in-type-2-diabetes-mellitus
#13
JOURNAL ARTICLE
Yi Zhang, Kemeng Zhang, Sui Huang, Wenhan Li, Ping He
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease characterized by hyperglycemia, insulin resistance, and insufficient insulin secretion. Sarcopenia, as a new complication of diabetes, is characterized by the loss of muscle mass and the progressive decline of muscle strength and function in T2DM patients, which has a serious impact on the physical and mental health of patients. Insulin resistance, mitochondrial dysfunction, and chronic inflammation are common mechanisms of diabetes and sarcopenia...
April 19, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38640241/coin-sized-fully-integrated-and-minimally-invasive-continuous-glucose-monitoring-system-based-on-organic-electrochemical-transistors
#14
JOURNAL ARTICLE
Jing Bai, Dingyao Liu, Xinyu Tian, Yan Wang, Binbin Cui, Yilin Yang, Shilei Dai, Wensheng Lin, Jixiang Zhu, Jinqiang Wang, Aimin Xu, Zhen Gu, Shiming Zhang
Continuous glucose monitoring systems (CGMs) are critical toward closed-loop diabetes management. The field's progress urges next-generation CGMs with enhanced antinoise ability, reliability, and wearability. Here, we propose a coin-sized, fully integrated, and wearable CGM, achieved by holistically synergizing state-of-the-art interdisciplinary technologies of biosensors, minimally invasive tools, and hydrogels. The proposed CGM consists of three major parts: (i) an emerging biochemical signal amplifier, the organic electrochemical transistor (OECT), improving the signal-to-noise ratio (SNR) beyond traditional electrochemical sensors; (ii) a microneedle array to facilitate subcutaneous glucose sampling with minimized pain; and (iii) a soft hydrogel to stabilize the skin-device interface...
April 19, 2024: Science Advances
https://read.qxmd.com/read/38640178/pressure-ulcers-acquired-during-inpatient-rehabilitation-after-spinal-cord-injury-characterization-and-predictors-a-15-years-experience
#15
JOURNAL ARTICLE
Alejandro García-Rudolph, Mark Andrew Wright, Emilien Amar Devilleneuve, Eulalia Castillo, Eloy Opisso, Elena Hernandez-Pena
BACKGROUND: Most studies focus on the risk factors associated with the development of pressure ulcers (PUs) during acute phase or community care for individuals with spinal cord injury (SCI). OBJECTIVES: This study aimed to i) compare clinical and demographic characteristics of inpatients after SCI with PUs acquired during rehabilitation vs inpatients without PUs and ii) evaluate an existing PU risk assessment tool iii) identify first PU predictors. METHODS: Individuals (n = 1,135) admitted between 2008 and 2022 to a rehabilitation institution within 60 days after SCI were included...
April 16, 2024: NeuroRehabilitation
https://read.qxmd.com/read/38640133/the-impact-of-obesity-induced-inflammation-on-clonal-hematopoiesis
#16
JOURNAL ARTICLE
Santhosh Kumar Pasupuleti, Reuben Kapur
PURPOSE OF REVIEW: This review meticulously delves into existing literature and recent findings to elucidate the intricate link between obesity and clonal hematopoiesis of indeterminate potential (CHIP) associated clonal hematopoiesis. It aims to enhance our comprehension of this multifaceted association, offering insights into potential avenues for future research and therapeutic interventions. RECENT FINDINGS: Recent insights reveal that mutations in CHIP-associated genes are not limited to symptomatic patients but are also present in asymptomatic individuals...
April 22, 2024: Current Opinion in Hematology
https://read.qxmd.com/read/38640128/the-impact-of-environmental-and-occupational-noise-on-maternal-and-perinatal-pregnancy-outcomes
#17
JOURNAL ARTICLE
Mara Ulin, Nneoma Edokobi, Brandon Ganjineh, Everett F Magann, Megan D Whitham
IMPORTANCE: Pregnant women are exposed to both occupational and environmental noise during their pregnancy. The association between noise and adverse health outcomes is well known. Less is known about the relationship between noise and its effects on the embryo/fetus and pregnancy. OBJECTIVES: The purpose of the study is to review what is known about the effect(s) of environment and occupational noise during pregnancy on maternal and perinatal outcomes. EVIDENCE ACQUISITION: Electronic databases (PubMed, CINAHL, and Embase) were searched from 1995-2023 with the only limitation being that the articles were in English...
April 2024: Obstetrical & Gynecological Survey
https://read.qxmd.com/read/38640098/spilanthes-filicaulis-schumach-thonn-c-d-adams-leaves-protects-against-streptozotocin-induced-diabetic-nephropathy
#18
JOURNAL ARTICLE
Oluwafemi Adeleke Ojo, Akingbolabo Daniel Ogunlakin, Christopher Oloruntoba Akintayo, Olaoluwa Sesan Olukiran, Juliana Bunmi Adetunji, Omolola Adenike Ajayi-Odoko, Theophilus Oghenenyoreme Ogwa, Olorunfemi Raphael Molehin, Omolara Olajumoke Ojo, Ramzi A Mothana, Abdullah R Alanzi
BACKGROUND AND OBJECTIVE: Diabetic neuropathy (DN) is a complex type of diabetes. The underlying cause of diabetic nephropathy remains unclear and may be due to a variety of pathological conditions resulting in kidney failure. This study examines the protective effect of the methanolic extract of Spilanthes filicaulis leaves (MESFL) in fructose-fed streptozotocin (STZ)-induced diabetic nephropathy and the associated pathway. METHODS: Twenty-five rats were equally divided randomly into five categories: Control (C), diabetic control, diabetic + metformin (100 mg/kg), diabetic + MESFL 150 mg/kg bw, and diabetic + MESFL 300 mg/kg bw...
2024: PloS One
https://read.qxmd.com/read/38640094/morin-based-nanoparticles-for-regulation-of-blood-glucose
#19
JOURNAL ARTICLE
Ziqi Hua, Yanfei Li, Tao Chen, Di Wu, Yu Xu, Jiang-Ning Hu
Morin, a naturally occurring bioactive compound shows great potential as an antioxidant, anti-inflammatory agent, and regulator of blood glucose levels. However, its low water solubility, poor lipid solubility, limited bioavailability, and rapid clearance in vivo hinder its application in blood glucose regulation. To address these limitations, we report an enzymatically synthesized nanosized morin particle (MNs) encapsulated in sodium alginate microgels (M@SA). This approach significantly enhances morin's delivery efficiency and therapeutic efficacy in blood glucose regulation...
April 19, 2024: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38640084/familial-hypercholesterolemia-plus-is-the-metabolic-syndrome-changing-the-clinical-picture-of-familial-hypercholesterolemia
#20
JOURNAL ARTICLE
Liam R Brunham
PURPOSE OF REVIEW: The purpose of this review article was to describe recent advances in our knowledge about how diabetes and metabolic syndrome are changing the face of familial hypercholesterolemia. RECENT FINDINGS: Heterozygous familial hypercholesterolemia, most commonly caused by disruption to LDL receptor function, leads to lifelong elevation of LDL cholesterol and increased risk of atherosclerotic cardiovascular disease. Familial hypercholesterolemia was originally described as a form of 'pure' hypercholesterolemia, in the sense that levels of LDL were uniquely affected...
April 22, 2024: Current Opinion in Lipidology
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