Meimei Guo, Yuxiang Wu, Danhao Zheng, Lei Chen, Bingrui Xiong, Jinfeng Wu, Ke Li, Li Wang, Kangguang Lin, Zongze Zhang, Anne Manyande, Fuqiang Xu, Jie Wang, Mian Peng
Preoperative sleep loss can amplify post-operative mechanical hyperalgesia. However, the underlying mechanisms are still largely unknown. In the current study, rats were randomly allocated to a control group and an acute sleep deprivation (ASD) group which experienced 6 h ASD before surgery. Then the variations in cerebral function and activity were investigated with multi-modal techniques, such as nuclear magnetic resonance, functional magnetic resonance imaging, c-Fos immunofluorescence, and electrophysiology...
October 25, 2022: Neuroscience Bulletin