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JOURNAL ARTICLE
Sumrah Jilani, Nina M D'Amiano, Katherine G Thompson, Jeremy Ellis, Anjali D'Amiano, Elena Wei, Kristin P Bibee, Jeffrey F Scott
No abstract text is available yet for this article.
September 5, 2023: Journal of the American Academy of Dermatology
#22
REVIEW
Edward C Kuan, Eric W Wang, Nithin D Adappa, Daniel M Beswick, Nyall R London, Shirley Y Su, Marilene B Wang, Waleed M Abuzeid, Borislav Alexiev, Jeremiah A Alt, Paolo Antognoni, Michelle Alonso-Basanta, Pete S Batra, Mihir Bhayani, Diana Bell, Manuel Bernal-Sprekelsen, Christian S Betz, Jean-Yves Blay, Benjamin S Bleier, Juliana Bonilla-Velez, Claudio Callejas, Ricardo L Carrau, Roy R Casiano, Paolo Castelnuovo, Rakesh K Chandra, Vasileios Chatzinakis, Simon B Chen, Alexander G Chiu, Garret Choby, Naweed I Chowdhury, Martin J Citardi, Marc A Cohen, Roi Dagan, Gianluca Dalfino, Iacopo Dallan, Camila Soares Dassi, John de Almeida, Angelo P Dei Tos, John M DelGaudio, Charles S Ebert, Ivan H El-Sayed, Jean Anderson Eloy, James J Evans, Christina H Fang, Nyssa F Farrell, Marco Ferrari, Nancy Fischbein, Adam Folbe, Wytske J Fokkens, Meha G Fox, Valerie J Lund, Gary L Gallia, Paul A Gardner, Mathew Geltzeiler, Christos Georgalas, Anne E Getz, Satish Govindaraj, Stacey T Gray, Jessica W Grayson, Bradley A Gross, Jordon G Grube, Ruifeng Guo, Patrick K Ha, Ashleigh A Halderman, Ehab Y Hanna, Richard J Harvey, Stephen C Hernandez, Adam L Holtzman, Claire Hopkins, Zhigang Huang, Zhenxiao Huang, Ian M Humphreys, Peter H Hwang, Alfred M Iloreta, Masaru Ishii, Michael E Ivan, Aria Jafari, David W Kennedy, Mohemmed Khan, Adam J Kimple, Todd T Kingdom, Anna Knisely, Ying-Ju Kuo, Devyani Lal, Eric D Lamarre, Ming-Ying Lan, Hien Le, Matt Lechner, Nancy Y Lee, Jivianne K Lee, Victor H Lee, Corinna G Levine, Jin-Ching Lin, Derrick T Lin, Brian C Lobo, Tran Locke, Amber U Luong, Kelly R Magliocca, Svetomir N Markovic, Gesa Matnjani, Erin L McKean, Cem Meço, William M Mendenhall, Loren Michel, Shorook Na'ara, Piero Nicolai, Daniel W Nuss, Gurston G Nyquist, Gretchen M Oakley, Kazuhiro Omura, Richard R Orlandi, Nobuyoshi Otori, Peter Papagiannopoulos, Zara M Patel, David G Pfister, Jack Phan, Alkis J Psaltis, Mindy R Rabinowitz, Murugappan Ramanathan, Ryan Rimmer, Marc R Rosen, Olabisi Sanusi, Zoukaa B Sargi, Philippe Schafhausen, Rodney J Schlosser, Ahmad R Sedaghat, Brent A Senior, Raj Shrivastava, Raj Sindwani, Timothy L Smith, Kristine A Smith, Carl H Snyderman, C Arturo Solares, Satyan B Sreenath, Aldo Stamm, Katharina Stölzel, Baran Sumer, Pavol Surda, Bobby A Tajudeen, Lester D R Thompson, Brian D Thorp, Charles C L Tong, Raymond K Tsang, Justin H Turner, Mario Turri-Zanoni, Aaron M Udager, Thibaut van Zele, Kyle VanKoevering, Kevin C Welch, Sarah K Wise, Ian J Witterick, Tae-Bin Won, Stephanie N Wong, Bradford A Woodworth, Peter-John Wormald, William C Yao, Chien-Fu Yeh, Bing Zhou, James N Palmer
BACKGROUND: Sinonasal neoplasms, whether benign and malignant, pose a significant challenge to clinicians and represent a model area for multidisciplinary collaboration in order to optimize patient care. The International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors (ICSNT) aims to summarize the best available evidence and presents 48 thematic and histopathology-based topics spanning the field. METHODS: In accordance with prior International Consensus Statement on Allergy and Rhinology documents, ICSNT assigned each topic as an Evidence-Based Review with Recommendations, Evidence-Based Review, and Literature Review based on the level of evidence...
February 2024: International Forum of Allergy & Rhinology
#23
JOURNAL ARTICLE
John F Thompson, Gabrielle J Williams
No abstract text is available yet for this article.
August 17, 2023: Aging
#24
JOURNAL ARTICLE
Jake R Thompson, Hong Fu, Robyn P M Saw, Kerry A Sherman, Victoria Beedle, Victoria Atkinson, Frances Boyle, Niamh A O'Sullivan, Linda K Martin, Iris Bartula
PURPOSE: This study aimed to investigate the supportive care needs of Australian melanoma patients and their caregivers to form the basis for improving services. METHODS: General and melanoma-related supportive care needs in melanoma patients were measured using the SCNS-SF34 and SCNS-M12 respectively, whereas caregivers completed the SCNS-P&C. Patients also completed the MCQ-28 and FCRI-9, with all participants completing the QLQ-C30, DASS-21, and questions measuring utilisation and preference for supportive health services...
July 31, 2023: Quality of Life Research
#25
JOURNAL ARTICLE
Ankita Mitra, Brian Thompson, Ann Strange, Carol M Amato, Melinda Vassallo, Igor Dolgalev, Jonathan Hester-McCullough, Tomoaki Muramatsu, Diana Kimono, Amrutesh S Puranik, Jeffrey S Weber, David Woods
PURPOSE: We previously showed that elevated frequencies of peripheral blood CD3+CD4+CD127-GARP-CD38+CD39+ T-cells was associated with checkpoint immunotherapy resistance in metastatic melanoma patients. In the present study we sought to further investigate this population of ectoenzyme expressing T-cells (Teee). Expeirmental Design: Teee derived from the peripheral blood of metastatic melanoma patients were evaluated by bulk RNA-seq and flow cytometry. The presence of Teee in the tumor microenviroment was assessed using publically available single-cell RNA-seq datasets of melanoma, lung, and bladder cancer along with multispectral immunofluorescent imaging of melanoma patient FFPE specimens...
July 28, 2023: Clinical Cancer Research
#26
JOURNAL ARTICLE
Brian Thompson, Ann Strange, Carol M Amato, Jonathan Hester-McCullough, Amod A Sarnaik, Jeffrey S Weber, David M Woods
Tumor-infiltrating lymphocyte (TIL) adoptive cell therapy is effective in treating malignant melanoma, but its success relies on the adequate ex vivo expansion of TIL. To assess correlates of TIL expansion, CD4+ and CD8+ TIL were analyzed by RNA sequencing (RNA-seq) and chromatin immunoprecipitation sequencing of acetylated histone 3. Patients were grouped into "TIL high" and "TIL low" based on division at the median number of TIL infused. Greater numbers of TIL infused correlated with longer overall survival, and increased frequencies of CD4+ cells infused were negatively correlated with the number of TIL infused...
July 19, 2023: Journal of Immunology
#27
JOURNAL ARTICLE
Iris Bartula, Anh D Tran, Anna K Nowak, Tasnia Ahmed, Rachael L Morton, Bryan H Burmeister, Kari Dolven-Jacobsen, Jenny Nobes, John F Thompson, Gerald B Fogarty, Serigne N Lo, Angela M Hong
PURPOSE: Brain metastases are common in patients with advanced melanoma. This study describes 12-month quality of life (QoL) trajectories following local management of 1-3 melanoma brain metastases. METHODS: This study assessed QoL data collected during a multi-center, prospective, open-label, phase III randomized controlled trial comparing the efficacy of adjuvant whole brain radiotherapy (WBRT) with observation after local treatment of 1-3 melanoma brain metastases...
July 2023: Clinical and Translational Radiation Oncology
#28
JOURNAL ARTICLE
Lilit Karapetyan, Hassan M AbuShukair, Aofei Li, Andrew Knight, Ayah Nedal Al Bzour, Ian P MacFawn, Zachary J Thompson, Ann Chen, Xi Yang, Rebekah Dadey, Arivarasan Karunamurthy, Danielle Vargas De Stefano, Cindy Sander, Sheryl R Kunning, Yana G Najjar, Diwakar Davar, Jason J Luke, William Gooding, Tullia C Bruno, John M Kirkwood, Walter J Storkus
BACKGROUND: Proinflammatory chemokines/cytokines support development and maturation of tertiary lymphoid structures (TLS) within the tumor microenvironment (TME). In the current study, we sought to investigate the prognostic value of TLS-associated chemokines/cytokines (TLS-kines) expression levels in melanoma patients by performing serum protein and tissue transcriptomic analyses, and to then correlate these data with patients clinicopathological and TME characteristics. METHODS: Levels of TLS-kines in patients' sera were quantitated using a custom Luminex Multiplex Assay...
2023: Frontiers in Immunology
#29
JOURNAL ARTICLE
Katherine G Thompson, Divya Manoharan, Raghav Tripathi, Emanuelle Rizk, Jonathan Lai, Jenny Carpenter, Davies Gage, Sumrah Jilani, Shirley Lin, Kristin P Bibee, Jeffrey F Scott
BACKGROUND: Despite the importance of patient satisfaction in ensuring high-quality care, studies investigating patient satisfaction in Mohs micrographic surgery (MMS) are limited. OBJECTIVE: We investigated the factors associated with patient satisfaction in MMS for non-melanoma skin cancer and how patient satisfaction changes in the post-operative period. METHODS: In this prospective cohort study including 100 patients, patient satisfaction surveys were administered at the time of surgery and at three months post-surgery...
July 6, 2023: Journal of the American Academy of Dermatology
#30
JOURNAL ARTICLE
Yu Jin Jeong, John F Thompson, Sydney Ch'ng
BACKGROUND AND OBJECTIVE: Mucosal melanoma of the head and neck (MMHN) are rare, aggressive neoplasms of melanocyte origin that remain incompletely understood and have a poor prognosis, with high rates of locoregional recurrence and distant metastasis. Several recent studies having expanded understanding of MMHN, we undertook a review of the latest evidence pertaining to its epidemiology, staging, and management. METHODS: A literature search was conducted for peer-reviewed articles reporting and discussing the epidemiology, staging, and management of MMHN...
June 2023: Chinese Clinical Oncology
#31
JOURNAL ARTICLE
Stephanie C Blake, Pascale Guitera, Anne E Cust, Claire Galea, Serigne N Lo, Richard A Scolyer, Bruce K Armstrong, John F Thompson, Scott W Menzies, Christine Madronio, Rachael L Morton, Graham J Mann, Caroline G Watts
No abstract text is available yet for this article.
August 2023: Australasian Journal of Dermatology
#32
JOURNAL ARTICLE
James V Talwar, David Laub, Meghana S Pagadala, Andrea Castro, McKenna Lewis, Georg E Luebeck, Bryan R Gorman, Cuiping Pan, Frederick N Dong, Kyriacos Markianos, Craig C Teerlink, Julie Lynch, Richard Hauger, Saiju Pyarajan, Philip S Tsao, Gerald P Morris, Rany M Salem, Wesley K Thompson, Kit Curtius, Maurizio Zanetti, Hannah Carter
Autoimmunity and cancer represent two different aspects of immune dysfunction. Autoimmunity is characterized by breakdowns in immune self-tolerance, while impaired immune surveillance can allow for tumorigenesis. The class I major histocompatibility complex (MHC-I), which displays derivatives of the cellular peptidome for immune surveillance by CD8+ T cells, serves as a common genetic link between these conditions. As melanoma-specific CD8+ T cells have been shown to target melanocyte-specific peptide antigens more often than melanoma-specific antigens, we investigated whether vitiligo- and psoriasis-predisposing MHC-I alleles conferred a melanoma-protective effect...
June 13, 2023: American Journal of Human Genetics
#33
JOURNAL ARTICLE
Mason J Webb, Timothy Kottke, Benjamin L Kendall, Jack Swanson, Chisom Uzendu, Jason Tonne, Jill Thompson, Muriel Metko, Madelyn Moore, Mitesh Borad, Lewis Roberts, Rosa M Diaz, Michael Olin, Antonella Borgatti, Richard Vile
In multiple models of oncolytic virotherapy, it is common to see an early anti-tumor response followed by recurrence. We have previously shown that frontline treatment with oncolytic VSV-IFN-β induces APOBEC proteins, promoting the selection of specific mutations that allow tumor escape. Of these mutations in B16 melanoma escape (ESC) cells, a C-T point mutation in the cold shock domain-containing E1 ( CSDE1 ) gene was present at the highest frequency, which could be used to ambush ESC cells by vaccination with the mutant CSDE1 expressed within the virus...
June 15, 2023: Molecular Therapy Oncolytics
#34
JOURNAL ARTICLE
Hannah Y Chen, Weilu Zhao, Shorook Na'ara, Frederico O Gleber-Netto, Tongxin Xie, Shahrukh Ali, Zachary M Thompson, Jane Buell, Haleigh Stafford, Priyadharsini Nagarajan, Michael Davies, Michael K Wong, Michael R Migden, Padmanee Sharma, Jeffrey N Myers, Neil D Gross, Moran Amit
PURPOSE: Although beta-blockers (BBs) have been hypothesized to exert a beneficial effect on cancer survival through inhibition of beta-adrenergic signaling pathways, clinical data on this issue have been inconsistent. We investigated the impact of BBs on survival outcomes and efficacy of immunotherapy in patients with head and neck squamous cell carcinoma (HNSCC), non-small-cell lung cancer (NSCLC), melanoma, or squamous cell carcinoma of the skin (skin SCC), independent of comorbidity status or cancer treatment regimen...
June 2023: JCO Precision Oncology
#35
JOURNAL ARTICLE
Andrew T Li, Jenaleen Law, Sydney Ch'ng, Richard A Scolyer, John F Thompson, Serigne N Lo, Alexander H R Varey
BACKGROUND: Calculating an accurate prognosis for melanoma patients who have a positive sentinel node (SN) biopsy is important both for them and for their treating doctors to guide decision-making, particularly when adjuvant systemic therapy is being considered. The recently published EORTC-DeCOG nomograms aim to provide this via an online portal that predicts 5-year rates for recurrence, distant metastasis and overall mortality. The present study provides external validation of these nomograms...
May 2, 2023: European Journal of Cancer
#36
JOURNAL ARTICLE
Daniel Tassone, Chamara Basnayake, Emily Wright, Mark Lust, Michael A Kamm, Ola Niewiadomski, Julien Schulberg, Emma Flanagan, Ms Tamie Samyue, Ms Stephanie Fry, Ms Ruth Malcolm, Ms Annalise Stanley, Alexander J Thompson, William R Connell, Nik Sheng Ding
BACKGROUND: Patients with IBD patients are at increased risk of malignancy and infection compared to the general population. AIMS: We aim to identify the risk factors for malignancy or serious infection in our IBD cohort. METHODS: IBD patients at an adult tertiary referral centre were included. Demographic and clinical details including immunosuppressant exposure were collected and medical records were retrospectively screened for adverse events including malignancy or infection requiring hospitalisation...
May 31, 2023: Internal Medicine Journal
#37
JOURNAL ARTICLE
Brandon Thompson, Toni Jenkins, John Paul Sánchez, Matthew Frederick, Alba Posligua-Alban, Naiara Sbroggio Barbosa
INTRODUCTION: There are vast differences in clinical presentations of melanoma across skin tones. Individuals with darker skin tones tend to have a higher prevalence of advanced-stage melanoma, which correlates with increased mortality. We designed this interactive workshop to increase nursing and medical trainees' awareness of the epidemiology, prevention, and treatment of melanoma in individuals of darker skin tones. METHODS: The Kern model was used in the design, implementation, and evaluation of the workshop...
2023: MedEdPORTAL Publications
#38
JOURNAL ARTICLE
Helena Robinson, Antonio Eleuteri, Joseph J Sacco, Rumana Hussain, Heinrich Heimann, Azzam F G Taktak, Bertil Damato, Alexander J Thompson, Thomas Allen, Helen Kalirai, Sarah E Coupland
Uveal melanoma (UM) metastasises in ~50% of patients, most frequently to the liver. Surveillance imaging can provide early detection of hepatic metastases; however, guidance regarding UM patient risk stratification for surveillance is unclear. This study compared sensitivity and specificity of four current prognostic systems, when used for risk stratification for surveillance, on patients treated at the Liverpool Ocular Oncology Centre (LOOC) between 2007-2016 ( n = 1047). It found that the Liverpool Uveal Melanoma Prognosticator Online III (LUMPOIII) or Liverpool Parsimonious Model (LPM) offered greater specificity at equal levels of sensitivity than the American Joint Committee on Cancer (AJCC) system or monosomy 3 alone, and suggests guidance to achieve 95% sensitivity and 51% specificity (i...
May 4, 2023: Cancers
#39
JOURNAL ARTICLE
John P Thompson, Georgette A Hattier, Elizabeth M Bozner, Jeremy J Wood, Kevin R Kirchner
No abstract text is available yet for this article.
May 12, 2023: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
#40
JOURNAL ARTICLE
Trine Schoenfeldt, Annette H Chakera, Omgo E Nieweg, John F Thompson
No abstract text is available yet for this article.
May 3, 2023: Annals of Surgical Oncology
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