Mohammad Ghorbani, Seyed Hassan Sadrian, Rezvan Ghaderpanah, Colin C Neitzke, Brian P Chalmers, Saeid Esmaeilian, Elham Rahmanipour, Ali Parsa
PURPOSE: This comprehensive review was conducted to assess the effects of tranexamic acid (TXA) on blood loss, venous thromboembolism (VTE) risk, and wound complications following total hip arthroplasty (THA). Additionally, it sought to evaluate the effects of various TXA dosages, modes of administration, and combinations with other antifibrinolytic drug. METHODS: In search of systematic reviews and meta-analyses on the use of TXA in THA patients, we searched extensively through databases including Scopus, the Cochrane Library, Embase, Medline, the Web of Science, PubMed, and Google Scholar...
August 2024: Journal of Orthopaedics