Dinorah Hernández-Melchor, Cecilia Palafox-Gómez, Ivan Madrazo, Ginna Ortiz, America Padilla-Viveros, Esther López-Bayghen
BACKGROUND: Polycystic ovary syndrome (PCOS) is an endocrine disease that combines metabolic, reproductive, and psychological dysfunctions. Ovulation disorders and impaired endometrial receptivity in PCOS can cause infertility. Insulin resistance (IR) is a pathological state of inadequate response to insulin that affects reproduction in PCOS, as damage caused by IR at the endometrial level becomes an obstacle for embryo implantation. Reversing IR resulted in spontaneous pregnancies in PCOS patients, indicating that metabolic corrections improve endometrial dysfunctions...
November 26, 2022: World Journal of Clinical Cases