Rong Yan, Yu Mao, Huiyang Zeng, Qian Liu, Hanqiu Jiang, Jingting Peng, Qingling Yang, Shilei Cui, Lei Liu, Yanjun Guo, Jiawei Wang
OBJECTIVE: Collapsin response mediator protein 5-associated optic neuropathy (CRMP5-ON) is a rare entity of autoimmune optic neuropathy. This study aimed to review the neuro-ophthalmic findings and outcomes in a series of patients with CRMP5-ON to further characterize its clinical phenotype, radiologic clues, and outcomes. METHODS: This was a retrospective case series and a single-center medical chart review of all patients with CRPM5-seropositive ON at the Department of Neurology, Beijing Tongren Hospital, from December 1, 2020, to March 31, 2023...
2023: Frontiers in Neurology