keyword
https://read.qxmd.com/read/38707712/bayesian-modelling-disentangles-language-versus-executive-control-disruption-in-stroke
#21
JOURNAL ARTICLE
Gesa Hartwigsen, Jae-Sung Lim, Hee-Joon Bae, Kyung-Ho Yu, Hugo J Kuijf, Nick A Weaver, J Matthijs Biesbroek, Jakub Kopal, Danilo Bzdok
Stroke is the leading cause of long-term disability worldwide. Incurred brain damage can disrupt cognition, often with persisting deficits in language and executive capacities. Yet, despite their clinical relevance, the commonalities and differences between language versus executive control impairments remain under-specified. To fill this gap, we tailored a Bayesian hierarchical modelling solution in a largest-of-its-kind cohort (1080 patients with stroke) to deconvolve language and executive control with respect to the stroke topology...
2024: Brain communications
https://read.qxmd.com/read/38707184/radiomics-analysis-of-pancreas-based-on-dual-energy-computed-tomography-for-the-detection-of-type-2-diabetes-mellitus
#22
JOURNAL ARTICLE
Wei Jiang, Xianpan Pan, Qunzhi Luo, Shiqi Huang, Yuhong Liang, Xixi Zhong, Xianjie Zhang, Wei Deng, Yaping Lv, Lei Chen
OBJECTIVE: To utilize radiomics analysis on dual-energy CT images of the pancreas to establish a quantitative imaging biomarker for type 2 diabetes mellitus. MATERIALS AND METHODS: In this retrospective study, 78 participants (45 with type 2 diabetes mellitus, 33 without) underwent a dual energy CT exam. Pancreas regions were segmented automatically using a deep learning algorithm. From these regions, radiomics features were extracted. Additionally, 24 clinical features were collected for each patient...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38707144/perceptions-on-medical-professionalism-among-future-healthcare-professionals-a-mixed-method-study
#23
JOURNAL ARTICLE
Vijaya Ramanathan, Punita Pushpanathan, Trupti Bodhare, Samir Bele
Background Accreditation councils across the world constantly examine policies and practices in professionalism in their medical curriculum. The National Medical Commission (NMC) in India has recognized the pressing need to reform and include professionalism in its undergraduate curriculum. Objectives The objective of this study was to explore the perspectives of medical and nursing students on professional behavior, suitable teaching-learning methods, and assessment strategies for curriculum integration. Methodology The study utilized a concurrent triangulation mixed method design, collecting both qualitative and quantitative data simultaneously to gain a comprehensive understanding of medical and nursing students' perceptions of professionalism...
April 2024: Curēus
https://read.qxmd.com/read/38707067/development-and-national-validation-of-a-musculoskeletal-emergency-medicine-assessment-tool
#24
JOURNAL ARTICLE
William Denq, Alexander J Tomesch, Tyler Jackson, Allison D Lane, Anna Waterbrook
Introduction Musculoskeletal (MSK) complaints and injuries are the fourth most common primary diagnosis in the emergency department in the United States (US). Despite the prevalence and economic impact on the US healthcare system, new emergency medicine (EM) residency graduates report feeling unprepared to treat MSK complaints. Currently, there are no reported means to assess MSK knowledge in EM resident physicians. The purpose of this study is to develop a validated and peer-reviewed multiple-choice assessment tool focused on MSK knowledge relevant to EM to allow us to better assess the knowledge of resident physicians...
April 2024: Curēus
https://read.qxmd.com/read/38707043/unilateral-pushup-induced-acute-median-neuritis
#25
Alexis M Ruppel, Mitchell J Lomis, Scarlett E Schneider
Acute median nerve neuropathy is most often due to trauma; acute carpal tunnel syndrome is considered a surgical emergency and must be ruled out. A right-hand dominant male presented to the emergency department with progressive unilateral pain and numbness in the median nerve distribution after experiencing a pop while doing pushups. The evaluation was limited to pain, but there was no gross deformity, and the distal right upper extremity was neurovascularly intact. All imaging was unremarkable. The patient received adequate pain control and complete resolution of symptoms...
April 2024: Curēus
https://read.qxmd.com/read/38706999/a-rare-case-of-severe-mitral-stenosis-presenting-as-cardiogenic-shock
#26
Lucas Garcia Reinoso, Sabu John
We report a case of severe mitral stenosis (MS) in a 58-year-old female from Guyana. Though rheumatic MS continues to be less prevalent in third-world countries, it poses a significant threat as far as morbidity and mortality are concerned. The modern definition of "Third World" is used to classify countries that are poor or developing. Countries that are part of the "third world" are generally characterized by (1) high rates of poverty, (2) economic and/or political instability, and (3) high mortality. The standard method of diagnosing MS in patients has been established as transthoracic echocardiograms (TTE), along with pertinent historical and physical exam findings...
April 2024: Curēus
https://read.qxmd.com/read/38705899/can-large-language-models-pass-official-high-grade-exams-of-the-european-society-of-neuroradiology-courses-a-direct-comparison-between-openai-chatgpt-3-5-openai-gpt4-and-google-bard
#27
JOURNAL ARTICLE
Gennaro D'Anna, Sofie Van Cauter, Majda Thurnher, Johan Van Goethem, Sven Haller
We compared different LLMs, notably chatGPT, GPT4, and Google Bard and we tested whether their performance differs in subspeciality domains, in executing examinations from four different courses of the European Society of Neuroradiology (ESNR) notably anatomy/embryology, neuro-oncology, head and neck and pediatrics. Written exams of ESNR were used as input data, related to anatomy/embryology (30 questions), neuro-oncology (50 questions), head and neck (50 questions), and pediatrics (50 questions). All exams together, and each exam separately were introduced to the three LLMs: chatGPT 3...
May 6, 2024: Neuroradiology
https://read.qxmd.com/read/38705764/sociodemographic-factors-associated-with-outpatient-radiology-no-shows-versus%C3%A2-cancellations
#28
JOURNAL ARTICLE
Arham Aijaz, Zuxian Hao, Thuan Gia-Nhat Tran, Desiree Anderson, Jarvish Shah, Gelareh Sadigh
RATIONALE AND OBJECTIVES: To assess prevalence of missed outpatient radiology appointments and sociodemographic factors associated with no-shows vs. cancellations. METHODS: Adults with outpatient radiology appointments in 2022 and January 2023 at a single tertiary academic health center were included. Generalized estimating equation regression was used to evaluate sociodemographic factors associated with missed vs. completed appointments, no-shows vs. cancellations and time interval between cancellations and appointments...
May 4, 2024: Academic Radiology
https://read.qxmd.com/read/38704947/utility-of-video-fluoroscopic-swallow-study-in-advancing-oral-diet-post-tors-for-oropharyngeal-malignancies
#29
JOURNAL ARTICLE
Courtney J Hunter, Natalie N Romaniw, Rachel Beckham, Soroush Farsi, Anna Benefield, Matthew Solverson, Emily A Gray, Emma Nguyen, Aubrey Marshall, Deanne King, Jumin Sunde, Mauricio Moreno, Emre Vural
OBJECTIVE: TORS is a minimally invasive surgical alternative to chemoradiotherapy for oropharyngeal malignancies. While early postoperative oropharyngeal dysphagia is linked to TORS, this study explores both subjective and objective swallowing outcomes. STUDY DESIGN: Retrospective and prospective review of the patients who underwent TORS for oropharyngeal malignancy from 2018 to 2023. SETTING: Single tertiary referral center. METHODS: Postoperative transnasal feeding tubes were administered to 142 patients undergoing TORS...
April 30, 2024: American Journal of Otolaryngology
https://read.qxmd.com/read/38704619/association-between-tight-junction-proteins-and-cognitive-performance-in-untreated-persons-living-with-hiv-plwh
#30
JOURNAL ARTICLE
Francesca Bai, Valeria Bono, Lidia Borghi, Federica Bonazza, Camilla Falcinella, Virginia Vitaletti, Federica Miraglia, Mattia Trunfio, Andrea Calcagno, Jessica Cusato, Elena Vegni, Antonella D'arminio Monforte, Giulia Marchetti
BACKGROUND: HIV-associated neurocognitive disorders (HAND) still affects persons living with HIV (PLWH) and their pathogenesis isn't completely understood. We aimed to explore the association between plasma and CSF markers of blood-brain barrier (BBB) impairment and HAND in untreated PLWH. DESIGN: Cross-sectional study. METHODS: We enrolled untreated PLWH, who underwent blood exams and lumbar puncture to measure inflammation (IL-15, TNF-α), BBB damage (zonulin and tight junction proteins, TJs: occludin, claudin-5) and endothelial adhesion molecules (VCAM-1, ICAM-1)...
May 3, 2024: AIDS
https://read.qxmd.com/read/38704615/delayed-recovery-from-ataxic-dementia-following-liposuction
#31
JOURNAL ARTICLE
Ana Clara de Oliveira, Marcos Benchimol, Ilana Benchimol, Leila Chimelli, Ricardo de Oliveira-Souza
A 19-year-old student developed hypoventilation and cyanosis at the end of a cosmetic liposuction procedure. She was awake, but severely abulic, disoriented, and unable to stand and walk due to severe locomotor ataxia. Neuropsychological evaluation showed psychomotor slowness, and deficits in memory encoding and retrieval, and on executive, and visuospatial and visuoperceptual tests; oral comprehension and constructional praxis were spared. ¹H-MRS showed a reduction of NAA. A year later, her cognitive and neurological exam, and NAA returned to normal, and she resumed her normal life...
May 4, 2024: Neurocase
https://read.qxmd.com/read/38703940/associations-between-hysterectomy-and-metabolic-syndrome-the-multi-ethnic-study-of-atherosclerosis
#32
JOURNAL ARTICLE
Eric K Broni, Justin B Echouffo Tcheugui, Anna Palatnik, Ernest M Graham, Ruth-Alma Turkson-Ocran, Yvonne Commodore-Mendah, Chiadi E Ndumele, Erin D Michos
BACKGROUND: Metabolic syndrome is linked to an increased risk of incident cardiovascular disease (CVD) and all-cause mortality. Notable associations exist between hysterectomy with bilateral salpingo-oophorectomy and metabolic syndrome. However, there is emerging evidence that even with ovarian conservation, hysterectomy may be independently associated with long-term CVD risk. OBJECTIVE: To examine the associations between hysterectomy with ovarian preservation and metabolic syndrome risk in a multi-ethnic cohort...
May 2, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38703939/multidisciplinary-approach-to-evaluation-of-rectovaginal-fistulas
#33
JOURNAL ARTICLE
Jaclyn M Muñoz, Pamela J Levin, Nicole M Saur, Caroline K Cox
Thorough evaluation of a rectovaginal fistula (RVF) is essential to optimize surgical repair. The underlying cause should be addressed and treated, which can affect the timing as well as approach to repair. It is imperative to be well-prepared as the highest chance of successful closure occurs during the initial repair attempt. Our objective is to demonstrate how multidisciplinary colorectal surgery and urogynecology teams use specific methods during exam under anesthesia to evaluate a complex RVF and optimize surgical approach to repair...
May 2, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38703938/ovarian-cancer-risk-among-older-patients-with-stable-adnexal-masses
#34
JOURNAL ARTICLE
Elizabeth J Suh-Burgmann, Yun-Yi Hung, Julie A Schmittdiel
BACKGROUND: Few studies have evaluated the risk of cancer among older patients with stable adnexal masses in community-based settings to inform the duration of observation time needed. OBJECTIVE: To assess ovarian cancer risk among older patients with stable adnexal masses on ultrasound. STUDY DESIGN: Retrospective cohort study of patients in a large community-based health system, aged > 50 years with an adnexal mass < 10 cm on ultrasound between 2016-2020 who had at least one follow-up ultrasound done > 6 weeks following initial ultrasound...
April 23, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38703355/experimental-measurement-of-local-noise-power-spectrum-nps-in-photon-counting-detector-ct-pcd-ct-using-a-single-data-acquisition
#35
JOURNAL ARTICLE
Chengzhu Zhang, Ke Li, Ran Zhang, Guang-Hong Chen
BACKGROUND: Accurate noise power spectra (NPS) measurement in clinical X-ray CT exams is challenging due to the need for repeated scans, which expose patients to high radiation risks. A reliable method for single CT acquisition NPS estimation is thus highly desirable. PURPOSE: To develop a method for estimating local NPS from a single photon counting detector-CT (PCD-CT) acquisition. METHODS: A novel nearly statistical bias-free estimator was constructed from the raw counts data of PCD-CT scan to estimate the variance of sinogram projection data...
May 4, 2024: Medical Physics
https://read.qxmd.com/read/38703091/screening-the-implant-augmented-breast-with-digital-breast-tomosynthesis-is-tomosynthesis-necessary-for-non-implant-displaced-views
#36
JOURNAL ARTICLE
Derek L Nguyen, Lars J Grimm, Jeffrey S Nelson, Karen S Johnson, Sujata V Ghate
OBJECTIVE: To determine cancer visualization utility and radiation dose for non-implant-displaced (ID) views using standard protocol with digital breast tomosynthesis (DBT) vs alternative protocol with 2D only when screening women with implant augmentation. METHODS: This retrospective cohort study identified women with implants who underwent screening DBT examinations that had abnormal findings from July 28, 2014, to December 31, 2021. Three fellowship-trained breast radiologists independently reviewed examinations retrospectively to determine if the initially identified abnormalities could be visualized on standard protocol (DBT with synthesized 2D (S2D) for ID and non-ID views) and alternate protocol (DBT with S2D for ID and only the S2D images for non-ID views)...
May 4, 2024: Journal of breast imaging
https://read.qxmd.com/read/38702083/factors-influencing-optimal-diabetes-care-and-clinical-outcomes-in-thai-patients-with-type-2-diabetes-mellitus-a-multilevel-modelling-analysis
#37
JOURNAL ARTICLE
Apinya Surawit, Tanyaporn Pongkunakorn, Thamonwan Manosan, Pichanun Mongkolsucharitkul, Parinya Chamnan, Krishna Suvarnabhumi, Thanapat Puangpet, Sophida Suta, Sureeporn Pumeiam, Bonggochpass Pinsawas, Suphawan Ophakas, Sananon Pisitpornsuk, Chalita Utchin, Korapat Mayurasakorn
BACKGROUND: Increasing levels of poor glycaemic control among Thai patients with type 2 diabetes mellitus (T2DM) motivated us to compare T2DM care between urban and suburban primary care units (PCUs), to identify gaps in care, and to identify significant factors that may influence strategies to enhance the quality of care and clinical outcomes in this population. METHODS: We conducted a cross-sectional study involving 2160 patients with T2DM treated at four Thai PCUs from 2019 to 2021, comprising one urban and three suburban facilities...
May 3, 2024: BMJ Open
https://read.qxmd.com/read/38702066/implementation-of-a-survey-spine-magnetic-resonance-imaging-protocol-for-cord-compression-in-the-emergency-department-experience-at-a-level-1-trauma-center
#38
JOURNAL ARTICLE
Mercy H Mazurek, Annie R Abruzzo, Alexander H King, Erica Koranteng, Grant Rigney, Winston Lie, Shahaan Razak, Rajiv Gupta, William A Meehan, Michael H Lev, Joshua A Hirsch, Karen Buch, Marc D Succi
BACKGROUND AND PURPOSE: Imaging stewardship in the emergency department (ED) is vital in ensuring patients receive optimized care. While suspected cord compression (CC) is a frequent indication for total spine MRI in the ED, the incidence of CC is low. Recently, our level-I trauma center introduced a survey spine MRI protocol to evaluate for suspected CC while reducing exam time to avoid imaging overutilization. This study aims to evaluate the time savings, frequency of ordering patterns of the survey, and the symptoms and outcomes of patients undergoing the survey...
May 3, 2024: AJNR. American Journal of Neuroradiology
https://read.qxmd.com/read/38701730/otolaryngology-head-and-neck-surgery-resident-and-medical-school-characteristics-current-paradigm-amidst-changing-application-criteria
#39
JOURNAL ARTICLE
Radhika Duggal, August A Culbert, Eduardo Williams-Medina, Julia T Tanzo, William S Tierney
PURPOSE: To determine the characteristics of current US Otolaryngology-Head and Neck Surgery (Oto-HNS) residents and their medical school. METHODS: Data were manually collected between Dec 2022 and Jan 2023 for 1649 residents attending 163 US-based ACGME accredited Oto-HNS residency programs, reflecting the 2018-2022 cohort. All data were collected from publicly available sources including residency and medical school program websites, web of science, and professional networking sites (ex: LinkedIn, Doximity)...
April 29, 2024: American Journal of Otolaryngology
https://read.qxmd.com/read/38700954/comparative-proteomics-identified-exosc1-as-a-target-protein-of-anticancer-peptide-lvtx-8-in-nasopharyngeal-carcinoma-cells
#40
JOURNAL ARTICLE
Ganghua Zhu, Lingxiang Wang, Xingyao Wang, Xiaoping Dong, Shu Yang, Jiaqi Wang, Siyuan Xu, Yong Zeng
Nasopharyngeal carcinoma (NPC) is a prevalent malignancy that usually occurs among the nose and throat. Due to mild initial symptoms, most patients are diagnosed in the late stage, and the recurrence rate of tumors is high, resulting in many deaths every year. Traditional radiotherapy and chemotherapy are prone to causing drug resistance and significant side effects. Therefore, searching for new bioactive drugs including anticancer peptides is necessary and urgent. LVTX-8 is a peptide toxin synthesized from the cDNA library of the spider Lycosa vittata, which is consisting of 25 amino acids...
May 3, 2024: Journal of Proteome Research
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