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JOURNAL ARTICLE
Shinji Miwa, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Kentaro Igarashi, Kaoru Tada, Yuta Taniguchi, Sei Morinaga, Yohei Asano, Hiroyuki Tsuchiya
AIMS: Surgical site infection (SSI) after soft-tissue sarcoma (STS) resection is a serious complication. The purpose of this retrospective study was to investigate the risk factors for SSI after STS resection, and to develop a nomogram that allows patient-specific risk assessment. METHODS: A total of 547 patients with STS who underwent tumour resection between 2005 and 2021 were divided into a development cohort and a validation cohort. In the development cohort of 402 patients, the least absolute shrinkage and selection operator (LASSO) regression model was used to screen possible risk factors of SSI...
May 1, 2024: Bone & Joint Journal
#42
JOURNAL ARTICLE
Hope Knochenhauer, Stephanie Lim, Laura Havrilesky, Sarah Dotters-Katz
OBJECTIVE: The objective of this study was to compare the cost and effectiveness of three strategies for screening and/or treating bacterial vaginosis (BV) during pregnancy prior to delivery: (1) the current standard of care, neither test nor treat for BV (Treat None); (2) test all patients for BV at 36 weeks gestation; treat if positive (Test Treat); and (3) treat all patients undergoing cesarean delivery with intravenous metronidazole at time of surgery (Treat All Cesarean). Effectiveness was defined as avoidance of postpartum surgical site infection...
April 30, 2024: American Journal of Perinatology
#43
JOURNAL ARTICLE
Yu Li, Ting Ye, Xiao-Lu Zhang, Hui Yang, Yan Wu, Bao-Hua Huang, Qi Zhao, Yu-Feng Gu
Background: This study aims to elucidate the clinical characteristics of Shewanella -related surgical site infections (SSIs) and assess the risk of mortality in patients by establishing a predictive model. Patients and Methods: A retrospective analysis of medical history and laboratory data of Shewanella -related SSI patients over the past decade was conducted via the electronic medical record (EMR) system. A predictive model for mortality risk in Shewanella -related SSI patients was established using plasma interleukin-6 (IL-6) levels combined with the Howell-PIRO scoring system...
April 29, 2024: Surgical Infections
#44
JOURNAL ARTICLE
Christopher D Seaver, Sara J Morgan, Candice S Legister, Casey L Palmer, Eduardo C Beauchamp, Tenner J Guillaume, Walter H Truong, Steven E Koop, Joseph H Perra, John E Lonstein, Daniel J Miller
PURPOSE: To describe the incidence of reoperation and factors contributing to surgical revision within a minimum of 10 years after spinal fusion for scoliosis in patients with nonambulatory cerebral palsy (CP). METHODS: We conducted a retrospective review of consecutive nonambulatory patients with CP who underwent primary spinal fusion at a single specialty care center with a minimum of 10 years from their index surgery (surgery dates 2001-2011). Causes of reoperation were classified as implant failure/pseudoarthrosis, surgical site infection (SSI), proximal junctional kyphosis, prominent/symptomatic implants, and implant removal...
April 29, 2024: Spine Deformity
#45
JOURNAL ARTICLE
Mengistu G Mengesha, Shanmuganathan Rajasekaran, Karthik Ramachandran, Vetrivel Chezian Sengodan, Nor Faissal Yasin, Luke Michael Williams, Maritz Laubscher, Kota Watanabe, O Z M Dastagir, Akinola Akinmadr, Hizkyas K Fisseha, Amer Aziz, Ratko Yurac, Ephrem Gebrehana, Mohammed AlSaifi, Kalaventhan Pathinathan, G Sudhir, Amran Ahmed Shokri, Yong Chan Kim, Sharif Ahmed Jonayed, Gonzalo R Kido, Jose Manuel Ignacio, Matiyas Seid Mohammed, Kabir Abubakar, Jonaed Hakim, Sailendra Kumar Duwal Shrestha, Abdullah Al Mamun Choudhury, Malick Diallo, Marcelo Molina, Sandeep Patwardhan, Yong Hai, Ali M Ramat, Momotaro Kawai, Jae Hwan Cho, Rosan Prasad Shah Kalawar, Sung-Woo Choi, Baron Zarate-Kalfopulos, Alfredo Guiroy, Nelson Astur, AlexisD B Buunaaim, Anton L Human, Atiq Uz Zaman
PURPOSE: Improper utilization of surgical antimicrobial prophylaxis frequently leads to increased risks of morbidity and mortality.This study aims to understand the common causative organism of postoperative orthopedic infection and document the surgical antimicrobial prophylaxis protocol across various institutions in to order to strengthen surgical antimicrobial prophylaxis practice and provide higher-quality surgical care. METHODS: This multicentric multinational retrospective study, includes 24 countries from five different regions (Asia Pacific, South Eastern Africa, Western Africa, Latin America, and Middle East)...
September 2024: Journal of Orthopaedics
#46
JOURNAL ARTICLE
Mason T Stoltzfus, Kenny Nguyen, Zachary Freedman, David R Hallan, Jinpyo Hong, Elias Rizk
Objective Spinal fusions are gaining popularity as a means of treating spinal deformity and instability from a range of pathologies. The prevalence of glucocorticoid use has also increased in recent decades, and their systemic effects are well-documented. Although commonly used in the preoperative period, the effects of steroids on outcomes among patients undergoing spinal fusions are inadequately described. This study compares the odds of developing complications among patients who underwent single-level lumbar fusions with and without preoperative glucocorticoid use in hopes of establishing more evidence-based parameters for guiding preoperative steroid use...
March 2024: Curēus
#47
JOURNAL ARTICLE
Véronique M Doucet, Jakob J Weirathmueller, Graham J McLeod, Kenneth A Murray
Introduction: Breast reduction mammoplasty (BRM) is a common procedure performed by plastic surgeons treating patients with hypermastia. It is customary to give preoperative prophylactic intravenous antibiotics for BRM, followed by several days of postoperative prophylactic oral antibiotics, despite the lack of evidence of their effectiveness in preventing surgical site infections (SSIs). The purpose of this study is to determine if the addition of prophylactic postoperative antibiotics is more effective in preventing SSIs in comparison to a single dose of preoperative prophylactic antibiotics in BRM...
May 2024: Plastic Surgery
#48
EDITORIAL
Ashim Gupta, Vijay Kumar Jain
Surgical site infections (SSI) following total joint arthroplasty pose a significant concern for both providers and patients across the globe. Currently, administration of antimicrobial antibiotic prophylaxis is used throughout the world to reduce the incidence of SSI. However, the correct dosage and frequency of administration remains debatable. In this editorial, we emphasized the determination of the effect of administration of weight-adjusted antimicrobial antibiotic prophylaxis regime on the incidence of SSI and postoperative dosage reduction compared to the conventionally used regime during total joint arthroplasty...
April 18, 2024: World Journal of Orthopedics
#49
JOURNAL ARTICLE
Kislay Kant, Zeeshan Ahmed, Rohit Dama, Monish Karunakaran, Prateek Arora, Pradeep Rebala, Guduru Venkat Rao
BACKGROUNDS/AIMS: This trial evaluated whether anti-inflammatory agents hydrocortisone (H) and indomethacin (I) could reduce major complications after pancreatoduodenectomy (PD). METHODS: Between June 2018 and June 2020, 105 patients undergoing PD with > 40% of acini on the intraoperative frozen section were randomized into three groups (35 patients per group): 1) intravenous H 100 mg 8 hourly, 2) rectal I suppository 100 mg 12 hourly, and 3) placebo (P) from postoperative day (POD) 0-2...
April 29, 2024: Annals of Hepato-Biliary-Pancreatic Surgery
#50
JOURNAL ARTICLE
Patrick Nian, Faisal Elali, Lucas C Voyvodic, Ariel Rodriguez, Mitchell K Ng, Amr A Abdelgawad, Afshin E Razi
Surgical site infections (SSIs) are a notable complication following open reduction and internal fixation (ORIF) for ankle fractures. The purpose of this study was to (1) compare baseline demographics of patients who did and did not develop SSIs within 90 days following ORIF for trimalleolar ankle fractures and (2) identify risk factors associated with SSIs in this setting. A retrospective analysis from 2010 to 2020 was completed using a national administrative database. The study group consisted of patients who underwent ORIF for trimalleolar ankle fractures and developed SSIs within 90 days postoperatively...
April 26, 2024: Journal of Foot and Ankle Surgery
#51
REVIEW
Alessandro Fiocco, Martina Dini, Giulia Lorenzoni, Dario Gregori, Andrea Colli, Laura Besola
BACKGROUND: Surgical site infections (SSi) pose a frequent complication in cardiac surgery patients and lead to increased patient discomfort and extended hospitalization. AIM: This meta-analysis evaluates the protective role of single-use-negative-pressure-wound-therapy (sNPWT) devices on closed surgical wounds after cardiac surgery, and explores their potential preventive application across all cardiac surgery patients. METHODS: A comprehensive literature search was conducted on PubMed and Elsevier, focusing on studies related to "negative pressure wound therapy" or "PICO negative pressure wound therapy" combined with "cardiac surgery" or "sternotomy," published between 2000 and 2022...
April 25, 2024: Journal of Hospital Infection
#52
JOURNAL ARTICLE
Laura Rodríguez Lorenzo, Eduardo Arrea Salto, Elena González Cañas, Zoilo Madrazo González, Marta Santos Espi, Antonio Giménez Gaibar
OBJECTIVE: This study assessed the potential benefits of using incisional negative pressure wound therapy (iNPWT) for patients undergoing revascularisation due to peripheral arterial disease. METHODS: A prospective randomised controlled trial was conducted to compare the inguinal application of iNPWT vs. standard surgical dressings. Patients were enrolled from February 2021 to November 2022. A total of 133 groin incisions were randomised (66 intervention group, 67 control group)...
April 25, 2024: European Journal of Vascular and Endovascular Surgery
#53
JOURNAL ARTICLE
Logan Galansky, Andrew T Gabrielson, Andrew J Cohen
OBJECTIVES: To compare outcomes among patients undergoing first-time urethroplasty with buccal mucosa graft (BMG) who receive post-operative antibiotics versus those who do not. METHODS: A retrospective cohort study was conducted using the TriNetX claims database between 2008-2022. Using CPT, ICD10, and LOINC codes, patients >18 years old undergoing primary urethroplasty with BMG who received an outpatient prescription for antibiotics between post-operative day 0-30 or did not were queried...
April 25, 2024: Urology
#54
RANDOMIZED CONTROLLED TRIAL
Filippo Carannante, Gianluca Costa, Valentina Miacci, Gianfranco Bianco, Gianluca Masciana, Sara Lauricella, Marco Caricato, Gabriella Teresa Capolupo
BACKGROUND: Protective stoma after rectal surgery has been associated with important complications. The most common is surgical site infection (SSI) high rates after stoma reversal reported in literature. Our study compared the rate of SSI of two skin closure techniques, linear closure, and purse string closure. METHODS: We carried out a single center, prospective, randomized controlled trial in the Department of Colorectal Surgery of Fondazione Policlinico Campus Bio-Medico of Rome between January 2018 through December 2021, to compare LC vs PS closure of ileostomy sites...
April 27, 2024: Langenbeck's Archives of Surgery
#55
JOURNAL ARTICLE
Francisco J Ávila, Pilar Casado, Mª Concepción Marcellán, Laura Remón, Jorge Ares, Mª Victoria Collados, Sofía Otín
Spatial aspects of visual performance are usually evaluated through visual acuity charts and contrast sensitivity (CS) tests. CS tests are generated by vanishing the contrast level of the visual charts. However, the quality of retinal images can be affected by both ocular aberrations and scattering effects and none of those factors are incorporated as parameters in visual tests in clinical practice. We propose a new computational methodology to generate visual acuity charts affected by ocular scattering effects...
April 10, 2024: Journal of Imaging
#56
JOURNAL ARTICLE
Cristiana-Manuela Cojocaru, Cosmin Octavian Popa, Alina Schenk, Zsolt Jakab, Bogdan Andrei Suciu, Peter Olah, Horațiu Popoviciu, Simona Szasz
BACKGROUND AND OBJECTIVES: Defined by chronic pain, rheumatic diseases are often co-occurring with anxiety and depression. Among the available psychological interventions, cognitive-behavioral therapies have an already-proven efficiency in these cases. However, the need to adjust their structure became ubiquitous during the post-pandemic period. Hence, the objective of this study was to investigate the impact of a single-session, process-based cognitive-behavioral intervention for patients with rheumatic conditions within an in-patient setting...
April 15, 2024: Behavioral Sciences
#57
JOURNAL ARTICLE
Hayoung Lee, Jong Lyul Lee, Ji Sung Lee, Chan Wook Kim, Yong Sik Yoon, In Ja Park, Seok-Byung Lim
BACKGROUND: Prophylactic antibiotics (PAs) are standard for preventing surgical site infections (SSIs) post-colorectal surgery. This study aims to compare the effect of additional empiric oral antibiotics (OAs) alongside routine PAs to identify SSI risk factors. METHODS: A retrospective observatory analysis was conducted from January 2019 to December 2022 at Asan Medical Center, Seoul, Korea. The cohort was divided into two groups: PA given 1 h before surgery and discontinued within 24 h, and OA administered empiric OAs during mechanical bowel preparation in addition to PA...
April 26, 2024: World Journal of Surgery
#58
JOURNAL ARTICLE
Eric D Goldstein, Shadi Yaghi
Recent small subcortical infarcts (SSI) are a common radiographic predecessor to lacunar stroke. SSI is comprised of several pathophysiologic processes such as branch atherosclerotic disease (BAD) and lipohyalinosis, both of which have differing outcomes and natural history. Presently, there is not a proven method to determine whether a SSI is due to BAD or lipohyalinosis in non-stenotic vessels. However, high-resolution vessel wall imaging (HRVWI) has been reported in East Asian cohorts. We aimed to use HRVWI to identify individuals with BAD-related SSI in a North American cohort...
April 2024: Neurohospitalist
#59
JOURNAL ARTICLE
Lily J Park, Daniel D'Souza, Tania Kazi, Felipe Rodriguez, Christopher Griffiths, Tyler McKechnie, Dominik Mertz, Pablo E Serrano
BACKGROUND: Preoperative antibiotic options for pancreaticoduodenectomy (PD) include cefoxitin (CX), piperacillin-tazobactam (PT), or combined cefazolin and metronidazole (CM). Recent studies suggest the superiority of PT over CX, but evidence for CM is unclear. OBJECTIVE: To explore the impact of preoperative antibiotic selection (CM vs. PT and CX vs. PT) on the development of surgical site infections (SSI). METHODS: Consecutive adult patients at one institution who underwent PD from November 2017 to December 2021 and received either CM, PT, or CX preoperatively, were included...
April 25, 2024: Journal of Surgical Oncology
#60
JOURNAL ARTICLE
Kimberly Wysocki, Judith F Zedreck Gonzalez, Dianxu Ren
Surgical site infections (SSIs) contribute to negative outcomes for patients and health care organizations. Compliance with clinical practice guidelines likely can help prevent SSIs. An interdisciplinary team at a regional referral center in Michigan sought to reduce SSIs by improving compliance with the facility's preoperative antibiotic selection, dosing, timing, and redosing protocol. The interventions for the quality improvement project included adding the preprocedural antibiotics and doses to the master OR schedule; holding an education session for all preoperative nurses, intraoperative nurses, and anesthesia professionals; and posting a reference guide in the preoperative and intraoperative areas...
May 2024: AORN Journal
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