María K Salomón-Flores, Josue Valdes-García, Alejandro O Viviano-Posadas, Diego Martínez-Otero, Joaquín Barroso-Flores, Iván J Bazany-Rodríguez, Alejandro Dorazco-González
Selective recognition of fructosyl amino acids in water by arylboronic acid-based receptors is a central field of modern supramolecular chemistry that impacts biological and medicinal chemistry. Fructosyl valine (FV) and fructosyl glycyl histidine (FGH) occur as N-terminal moieties of human glycated hemoglobin; therefore, the molecular design of biomimetic receptors is an attractive, but very challenging goal. Herein, we report three novel cationic Zn-terpyridine complexes bearing a fluorescent N -quinolinium nucleus covalently linked to three different isomers of strongly acidified phenylboronic acids ( ortho -, 2Zn; meta -, 3Zn and para -, 4Zn) for the optical recognition of FV, FGH and comparative analytes (D-fructose, Gly, Val and His) in pure water at physiological pH...
May 3, 2024: Dalton Transactions: An International Journal of Inorganic Chemistry