Cara Herbers, Joseph Schroeder, Chiahao Lu, Helen Geng, Raymond Zhang, Jessica Mehregan, Kada Malakowsky, Arthur Erdman, Matthew D Johnson, Scott E Cooper
BACKGROUND: Postural instability is one of the most disabling motor symptoms of Parkinson's disease (PD) given its association with falls and loss of independence. Previous studies have assessed biomechanical measures of reactive stepping in response to perturbations, showing that individuals with PD exhibit inadequate postural responses to regain balance. RESEARCH QUESTION: Does dopamine replacement therapy normalize step length in response to balance perturbations? METHODS: In this study, we estimated reactive step length, to a postural perturbation, retrospectively from a dataset of frontal plane video using 2D motion tracking and direct linear transform methods...
March 2023: Gait & Posture