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JOURNAL ARTICLE
Aaron A Gurayah, Ruben Blachman-Braun, Christopher J Machado, Matthew M Mason, Helen Y Hougen, Ali Mouzannar, Mark L Gonzalgo, Bruno Nahar, Sanoj Punnen, Dipen J Parekh, Chad R Ritch
OBJECTIVES: The objective of this study is to investigate the association between major adverse cardiac events (MACE) and clinical factors of patients undergoing radical cystectomy (RC) for bladder cancer. MATERIALS AND METHODS: A retrospective analysis using the 2015-2020 National Surgical Quality Improvement Program database was performed on patients who underwent RC for bladder cancer. MACE was defined as any report of cerebrovascular accident, myocardial infarction, or thromboembolic events (pulmonary embolism or deep vein thrombosis)...
April 2024: BJUI compass
#2
JOURNAL ARTICLE
Carrie Ye, John T Schousboe, Suzanne N Morin, Lisa M Lix, Eugene V McCloskey, Helena Johansson, Nicholas C Harvey, John A Kanis, William D Leslie
Osteoporosis and cardiovascular disease (CVD) are highly prevalent in older women, with increasing evidence for shared risk factors and pathogenesis. Although FRAX was developed for the assessment of fracture risk, we hypothesized that it might also provide information on CVD risk. To test the ability of the FRAX tool and FRAX-defined risk factors to predict incident CVD in women undergoing osteoporosis screening with DXA, we performed a retrospective prognostic cohort study which included women aged 50 yr or older with a baseline DXA scan in the Manitoba Bone Mineral Density Registry between March 31, 1999 and March 31, 2018...
March 4, 2024: Journal of Bone and Mineral Research
#3
JOURNAL ARTICLE
Tadatsugu Morimoto, Takaomi Kobayashi, Hirohito Hirata, Masatsugu Tsukamoto, Tomohito Yoshihara, Yu Toda, Hayato Ito, Koji Otani, Masaaki Mawatari
INTRODUCTION: Perioperative cerebrovascular accidents (CVAs) related to spine surgery, although rare, can lead to significant disabilities. More studies on spine surgeries are required to identify those at risk of perioperative CVAs. The characteristics and outcomes of patients that experienced CVAs during spine surgery were assessed through a retrospective descriptive study and meta-analysis. METHODS: Patients aged ≥18 years who underwent spine surgery under general anesthesia at a hospital between April 2011 and March 2023 were examined...
March 27, 2024: Spine surgery and related research
#4
JOURNAL ARTICLE
Matthew S Chung, Neil Patel, George Abdelmalek, Daniel Coban, Stuart Changoor, Faisal Elali, Kumar Sinha, Ki Hwang, Arash Emami
BACKGROUND: Anterior cervical discectomy and fusion (ACDF) is a reliable procedure commonly performed in older patients with degenerative diseases of the cervical spine. Over 130,000 procedures are performed every year with an annual increase of 5%, and overall morbidity rates can reach as high as 19.3%, indicating a need for surgeons to gauge their patients' risk for adverse outcomes. Frailty is an age-associated decline in functioning of multiple organ systems and has been shown to predict adverse outcomes following various spine procedures...
June 2024: N Am Spine Soc J
#5
JOURNAL ARTICLE
B Ufuk Baldan, Romy R M J J Hegeman, Nelleke M J P Bos, Hans G Smeenk, Robert J M Klautz, Patrick Klein
Background : Post-cardiotomy cardiogenic shock (PCCS), which is defined as severe low cardiac output syndrome after cardiac surgery, has a mortality rate of up to 90%. No study has yet been performed to compare patients with PCCS treated by conservative means to patients receiving additional mechanical circulatory support with veno-arterial extracorporeal membrane oxygenation (ECMO). Methods : A single-center retrospective analysis from January 2018 to June 2022 was performed. Results : Out of 7028 patients who underwent cardiac surgery during this time period, 220 patients (3%) developed PCCS...
April 5, 2024: Journal of Clinical Medicine
#6
REVIEW
Anjali Mangesh Joshi, Arkiath Veettil Raveendran, Muruganathan Arumugam
Systemic hypertension is an established risk factor for coronary artery disease and cerebrovascular accident and control of blood pressure reduces the risk of a major cardiovascular event. Both non-pharmacological and pharmacological treatment options are available to treat hypertension. Yoga, recently received more attention as a treatment modality for various lifestyle disorders, even though practiced in India since ancient times. In this review, we are analyzing the role of yoga in the treatment of systemic hypertension...
March 20, 2024: World Journal of Methodology
#7
JOURNAL ARTICLE
Ramya Bakthavatchalam, Sriram Bakthavatchalam, Shyamala Ravikoti, Bhaskaran Shanmukham, Kotha S Reddy, Janardhana R Pallavali, Archana Gaur, Jeganathan Geetha, Sakthivadivel Varatharajan
Introduction COVID-19 exhibits a broad spectrum of clinical manifestations, ranging from asymptomatic or mild cases to severe respiratory distress and, in some instances, fatal outcomes. The pre-existing inflammatory state in the patient prior to exposure to COVID-19, which could be because of any etiology or comorbidity, has been associated with prolonged morbidity, and adverse outcomes like increased mortality have been found. This study endeavors to investigate the principal risk factors linked to the morbidity and mortality of COVID-19, such as age, gender, and co-morbidities such as hypertension, diabetes mellitus, and others...
March 2024: Curēus
#8
Ali Tariq Alvi, Elsa Tchouambou, Murali Shankar
INTRODUCTION: Upper gastrointestinal (GI) bleeding is a medical condition commonly seen in clinical practice due to variable etiologies and a multitude of presentations. The patients can present with hematemesis, melena, or hematochezia in case of severe bleeding. The initial evaluation should involve assessing the hemodynamic status with adequate resuscitation followed by diagnostic tests to identify the source and potentially treat it. Dieulafoy's lesion, sometimes referred to as Dieulafoy's disease, is a rare cause of upper GI bleeding with no clear risk factors, which makes it a diagnostic conundrum...
2024: HCA Healthc J Med
#9
JOURNAL ARTICLE
Cheuk Yin Wong, Becky M Y Ma, Danting Zhang, Wynn Cheung, Tak Mao Chan, Desmond Y H Yap
INTRODUCTION: It remains unclear how the presence of renal involvement will affect the cardiovascular (CV) risk factors and complications in patients with SLE. METHODS: We conducted a systematic review and meta-analysis using PubMed, EMBASE, MEDLINE and Scopus to identify studies published between 1947 and 2022 that evaluate the CV risk factors and complications in patients with SLE with or without lupus nephritis (LN). RESULTS: 58 studies were evaluated, with 22 two-arm studies (n=8675) included in two-arm meta-analysis and 45 studies (n=385 315) included in proportional meta-analysis...
March 21, 2024: Lupus Science & Medicine
#10
REVIEW
Sara J Cuccurullo, Talya K Fleming, Hayk Petrosyan
Stroke remains a top contributor to long-term disability in the United States and substantially limits a person's physical activity. Decreased cardiovascular capacity is a major contributing factor to activity limitations and is a significant health concern. Addressing the cardiovascular capacity of stroke survivors as part of poststroke management results in significant improvements in their endurance, functional recovery, and medical outcomes such as all-cause rehospitalization and mortality. Incorporation of a structured approach similar to the cardiac rehabilitation program, including aerobic exercise and risk factor education, can lead to improved cardiovascular function, health benefits, and quality of life in stroke survivors...
May 2024: Physical Medicine and Rehabilitation Clinics of North America
#11
Divine Besong Arrey Agbor, Derek Ugwendum, Barath Prashanth Sivasubramanian, Maureen A Ojwaka, Sabastain F Forsah, Shakirat Gold-Olufadi, Tochukwu Nzeako, Rita Offor, Nkafu Bechem Ndemazie, Jay Nfonoyim
Polycystic ovary syndrome (PCOS) is the leading cause of endocrine disorders among females of reproductive age and is linked with autoimmune disorders. PCOS has been associated with autoantibodies such as antinuclear antibody (ANA), anti-thyroid, and anti-Smith (anti-SM). Young patients with PCOS and systemic lupus erythematosus (SLE) have up to a 10-fold increase in stroke. We present a case of a patient with a history of PCOS (on metformin), hypothyroidism, and pulmonary embolism who presented to the emergency room with acute left-sided weakness...
February 2024: Curēus
#12
JOURNAL ARTICLE
Rashad J Belin, Travis B Desa, Igor Wroblewski, Cara Joyce, Anthony Perez-Tamayo, Jeffrey Schwartz, Lowell H Steen, John J Lopez, Bruce E Lewis, Ferdinand S Leya, Michael Tuchek, Mamdouh Bakhos, Verghese Mathew
BACKGROUND: Diastolic dysfunction is a predictor of poor outcomes in many cardiovascular conditions. At present, it is unclear whether diastolic dysfunction predicts adverse outcomes in patients with atypical aortic stenosis who undergo aortic valve replacement (AVR). METHODS: Five hundred and twenty-three patients who underwent transcatheter AVR (TAVR) (n = 303) and surgical AVR (SAVR) (n = 220) at a single institution were included in our analysis...
April 1, 2024: Journal of Cardiovascular Medicine
#13
REVIEW
Abdelrahman Elsebaie, Ayesha Shakeel, Shetuan Zhang, Marianne Alarie, Mohamed El Tahan, Mohammad El-Diasty
BACKGROUND: Reduced oxygen delivery (DO2 ) during cardiopulmonary bypass (CPB) was proposed as a risk factor for the development of postoperative neurological complications (PONCs), including cerebrovascular accidents (CVA), delirium, and postoperative cognitive dysfunction (POCD). We aimed to review the current evidence on the association between intraoperative DO2 and the incidence of PONCs. METHODS: MEDLINE, Embase, the Cochrane Library, and Web of Science were electronically searched to identify comparative studies from inception until July 2023 that reported the association between intraoperative DO2 levels and the incidence of PONCs (as defined by the scales and diagnostic tools utilized by the studies' authors) in adults patients undergoing cardiac surgery using CPB...
March 14, 2024: Perfusion
#14
Roger F Tonna, Azin Azma
Transient global amnesia (TGA) is a rare condition characterized by a temporary loss of the ability to form new memories. Retrograde episodic memory loss may also occur but to a lesser extent. Although TGA is generally benign, its sudden onset and similarity to more dangerous conditions like transient ischemic attack (TIA) or cerebral vascular accident (CVA) can be concerning. We present the case of a 70-year-old female who experienced confusion and general memory loss after a vigorous workout on her stationary exercise bike...
February 2024: Curēus
#15
JOURNAL ARTICLE
Kuan Chen, Yung-Chang Wang, Kuang-Tsu Yang, Ting-Hsin Huang, Yao-Min Hung, Renin Chang
BACKGROUND: Previous studies have suggested relationship between diverticular disease and cardiovascular disease. Since cardiovascular disease and cerebrovascular accident share a lot of pathogenesis, diverticulitis could also be a risk factor for stroke. This study tried to establish epidemiological evidence of the relationship between colon diverticulitis and ischemic stroke. METHODS: In this retrospective cohort study, patients with newly diagnosed colon diverticulitis (N = 6238) and patients without colon diverticulitis (control group; N = 24 952) were recruited between January 1, 2000, and December 31, 2017...
March 7, 2024: Postgraduate Medical Journal
#16
Alec J Knupp, Douglas A Smith
Ischemic stroke is defined as a reduction in blood flow to brain tissue that results in the deterioration and death of neurons in a matter of minutes. While often seen in older patients with a history of atherosclerosis of the major arteries, a subset of ischemic strokes occur in younger individuals with minimal to no prior risk factors. Further evaluation of these unknown, or cryptogenic, strokes has yielded positive findings of a patent foramen ovale (PFO) in a concerning number of cases. Cryptogenic strokes attributable to PFO present an important clinical occurrence because they do not fit the typical template regarding those most at risk for such acutely devastating outcomes, making their identification uniquely important for both immediate and long-term patient care...
February 2024: Curēus
#17
JOURNAL ARTICLE
Sheikha Al Hashmi, Shouq Al Hudar, Edwin Stephen, Dawood Al Riyami, Hanan Al Maawali, Ibrahim Abdelhady, Khalifa Al Wahaibi, Syed Rizvi
OBJECTIVES: This study aimed to determine the risk factors associated with the failure of arteriovenous fistulae (AVF) maturation. METHODS: This retrospective cohort study was conducted from January 2014 to December 2018 in Sultan Qaboos University Hospital, Muscat, Oman. Patients were followed-up 3 months after surgery, and their electronic medical records were accessed for demographic and clinical data. Univariate analysis was used to determine the risk factors associated with early AVF maturation and multivariant analysis was used to determine the predictive factors for AVF failure...
February 2024: Sultan Qaboos University Medical Journal
#18
JOURNAL ARTICLE
Fabiano Gonçalves Jucá, Fabiane Letícia de Freitas, Maxim Goncharov, Daniella de Lima Pes, Maria Eduarda Coimbra Jucá, Luis Roberto Palma Dallan, Luiz Augusto Ferreira Lisboa, Fábio B Jatene, Omar Asdrúbal Vilca Mejia
INTRODUCTION: Along with cardiopulmonary bypass time, aortic cross-clamping time is directly related to the risk of complications after heart surgery. The influence of the time difference between cardiopulmonary bypass and cross-clamping times (TDC-C) remains poorly understood. OBJECTIVE: To assess the impact of cardiopulmonary bypass time in relation to cross-clamping time on immediate results after coronary artery bypass grafting in the Registro Paulista de Cirurgia Cardiovascular (REPLICCAR) II...
March 1, 2024: Brazilian Journal of Cardiovascular Surgery
#19
REVIEW
Muhammad Ali Aziz, Srikaran Bojja, Ahmed Ali Aziz, Nismat Javed, Harish Patel
Stroke is an infarction of the central nervous system (brain, spinal cord, or retina) that results from a disruption in cerebral blood flow either due to ischemia or hemorrhage. Complications of acute stroke are common and include pneumonia, urinary tract infection, myocardial infarction, deep vein thrombosis, and pulmonary embolism, among several others, all of which increase the risk of poor clinical outcomes. Gastrointestinal bleeding is a well-known complication that can occur during the acute phase of stroke...
January 2024: Curēus
#20
MULTICENTER STUDY
Ahmed A H H Nasser, Manpreet Sidhu, Rohan Prakash, Ansar Mahmood, Khabab Osman, Govind S Chauhan, Rajpal Nandra, Varun Dewan, Jerome Davidson, Mohammed Al-Azzawi, Christian Smith, Mothana Gawad, Ioannis Palaiologos, Rory Cuthbert, Warran Wignadasan, Daniel Banks, James Archer, Abdulrahman Odeh, Thomas Moores, Muaaz Tahir, Margaret Brooks, Gurdeep Biring, Stevan Jordan, Zain Elahi, Mohammed Shaath, Manoj Veettil, Chiranjit De, Charles Handford, Mohit Bansal, Akshdeep Bawa, Ahmed Mattar, Varun Tandra, Audrina Daadipour, Ahmed Taha, Shafat Gangoo, Sriram Srinivasan, Mandishona Tarisai, Basil Budair, Krishna Subbaraman, Farrukh Khan, Austin Gomindes, Arjun Samuel, Niel Kang, Karan Kapur, Elizabeth Mainwaring, Hannah Bridgwater, Andre Lo, Usman Ahmed, Tahir Khaleeq, Ahmed El-Bakoury, Ramy Rashed, Hazem Hosny, Rathan Yarlagadda, Jonathan Keenan, Ahmed Hamed, Bryan Riemer, Arham Qureshi, Vatsal Gupta, Matthew Waites, Sabri Bleibleh, David Westacott, Jonathan Phillips, Jamie East, Daniel Huntley, Saqib Masud, Yusuf Mirza, Sandeep Mishra, David Dunlop, Mohamed Khalefa, Balasubramanian Balakumar, Mahesh Thibbaiah, Olivia Payton, James Berstock, Krisna Deano, Khaled M Sarraf, Kartik Logishetty, George Lee, Hariharan Subbiah-Ponniah, Nirav Shah, Aakaash Venkatesan, James Cheseldene-Culley, Joseph Ayathamattam, Samantha Tross, Sukhwinder Randhawa, Faisal Mohammed, Ramla Ali, Jonathan Bird, Kursheed Khan, Muhammad A Akhtar, Andrew Brunt, Panagiotis Roupakiotis, Padmanabhan Subramanian, Nelson Bua, Mounir Hakimi, Samer Bitar, Majed Al Najjar, Ajay Radhakrishnan, Charlie Gamble, Andrew James, Catherine Gilmore, Dan Dawson, Rajesh Sofat, Mohamed Antar, Aashish Raghu, Sam Heaton, Waleed Tawfeek, Christerlyn Charles, Henry Burnand, Sean Duffy, Luke Taylor, Laura Magill, Rita Perry, Michala Pettitt, Kelvin Okoth, Thomas Pinkney
AIMS: Periprosthetic fractures (PPFs) around the knee are challenging injuries. This study aims to describe the characteristics of knee PPFs and the impact of patient demographics, fracture types, and management modalities on in-hospital mortality. METHODS: Using a multicentre study design, independent of registry data, we included adult patients sustaining a PPF around a knee arthroplasty between 1 January 2010 and 31 December 2019. Univariate, then multivariable, logistic regression analyses were performed to study the impact of patient, fracture, and treatment on mortality...
February 1, 2024: Bone & Joint Journal
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