Rui Providencia, Ghazaleh Aali, Fang Zhu, Brian F Leas, Rachel Orrell, Mahmood Ahmad, Jonathan J H Bray, Ferruccio Pelone, Petra Nass, Eloi Marijon, Miryan Cassandra, David S Celermajer, Farhad Shokraneh
Secondary prevention with penicillin aims to prevent further episodes of acute rheumatic fever and subsequent development of rheumatic heart disease (RHD). Penicillin allergy, self-reported by 10% of the population, can affect secondary prevention programs. We aimed to assess the role for (i) routine penicillin allergy testing and the (ii) safety of penicillin allergy delabeling approaches in this context. We searched MEDLINE, Embase, CENTRAL, ClinicalTrials.gov, WHO ICTRP, ISRCTN, and CPCI-S to identify the relevant reports...
May 2, 2024: Clinical Reviews in Allergy & Immunology