Sina Nejati, Jiangshan Wang, Sotoudeh Sedaghat, Nicole K Balog, Amanda M Long, Ulisses Heredia Rivera, Venkat Kasi, Kinam Park, Jay S Johnson, Mohit Verma, Rahim Rahimi
The gastrointestinal (GI) tract, particularly the colon region, holds a highly diverse microbial community that plays an important role in the metabolism, physiology, nutrition, and immune function of the host body. Accumulating evidence has revealed that alteration in these microbial communities is the pivotal step in developing various metabolic diseases, including obesity, inflammatory bowel disease (IBD), and colorectal cancer. However, there is still a lack of clear understanding of the interrelationship between microbiota and diet as well as the effectiveness of chemoprevention strategies, including pre and probiotic agents in modifying the colonic microbiota and preventing digestive diseases...
September 23, 2022: Acta Biomaterialia