Jiawei Liu, Tingting Mai, Han Ren, Yafei Chang, Chao Li, Guoli Lv, Da Zheng, Xinbiao Liao, Yangeng Yu, Fu Zhang, Shuquan Zhao, Xiaoshan Liu, Shuiping Liu, Hu Zhao, Bin Luo, Chao Liu, Erwen Huang
Lysophosphoglycerides (LPLs) have been reported to accumulate in myocardium and serve as a cause of arrhythmias in acute myocardial ischemia. However, in this study we found that LPLs level in the ventricular myocardium was decreased by the onset of acute myocardial ischemia in vivo in rats. Decreasing of LPLs level in left ventricular myocardium, but not right, was observed within 26 min of left myocardial ischemia, regardless of whether arrhythmias were triggered. Lower LPLs level in the ventricular myocardium was also observed in aconitine-simulated ventricular fibrillation (P < 0...
April 26, 2024: Scientific Reports