Priya Rajendran, Silla Varghese Thomas, Sarath Balaji, Elilarasi Selladurai, Ganesh Jayachandran, Aravind Malayappan, Adhin Bhaskar, Sivaraman Palanisamy, Thirumalani Ramamoorthy, Sindhu Hasini, Syed Hissar
BACKGROUND: It has been reported that differential diagnosis of bacterial or viral pneumonia and tuberculosis (TB) in infants and young children is complex. This could be due to the difficulty in microbiological confirmation in this age group. In this study, we aimed to assess the utility of a real-time multiplex PCR for diagnosis of respiratory pathogens in children with pulmonary TB. METHODS: A total of 185 respiratory samples [bronchoalveolar lavage (15), gastric aspirates (98), induced sputum (21), and sputum (51)] from children aged 3-12 years, attending tertiary care hospitals, Chennai, India, were included in the study...
2024: Frontiers in Pediatrics