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REVIEW
Emel Kuram, Hasan Hüseyin Karadeli
Stroke is the second result for death and ischemic stroke constitutes most of all stroke cases. Ischemic stroke takes place when blood clot or embolus blocks cerebral vessel and interrupts blood flow, which often leads to brain damage, permanent disability, or death. There is a 4.5-hour (golden hour) treatment window to restore blood flow prior to permanent neurological impairment results. Current treatments of stroke consist mechanical system or thrombolytic drug therapy to disrupt or dissolve thrombus. Thrombolytics given more than 4...
May 5, 2024: Macromolecular Rapid Communications
#22
REVIEW
Ahmad Alhaskawi, Haiying Zhou, Yanzhao Dong, Sohaib Hasan Abdullah Ezzi, Xiaodi Zou, Zhou Weijie, Fangyu Yi, Sahar Ahmed Abdalbary, Hui Lu
BACKGROUND: While suture anchors are widely used in medical procedures for their advantages, they can sometimes lead to complications, including anchor prolapse. This article presents a unique case of suture anchor prolapse at the base of the distal phalanx of the little finger after extensor tendon rupture reconstruction surgery. CASE PRESENTATION: A 35-year-old male, underwent extensor tendon rupture reconstruction using a non-absorbable suture anchor. After seven years the patient visited our outpatients complaining of stiffness, pain, and protrusion at the surgical site...
May 4, 2024: BMC Musculoskeletal Disorders
#23
JOURNAL ARTICLE
Philipp Lambach, Sheetal Silal, Alyssa N Sbarra, Mitsuki Koh, Rakesh Aggarwal, Habib Hasan Farooqui, Stefan Flasche, Alexandra B Hogan, Sun-Young Kim, Kathy Leung, William J Moss, Patrick K Munywoki, Allison Portnoy, Meru Sheel, Xuan-Yi Wang
The Immunization and Vaccine-related Implementation Research Advisory Committee (IVIR-AC) is the World Health Organization's key standing advisory body to conduct an independent review of research, particularly of transmission and economic modeling analyses that estimate the impact and value of vaccines. From 26th February-1st March 2024, at its first of two semi-annual meetings, IVIR-AC provided feedback and recommendations across four sessions; this report summarizes the proceedings and recommendations from that meeting...
May 3, 2024: Vaccine
#24
JOURNAL ARTICLE
Lalani L Munasinghe, Weijia Yin, Hasan Nathani, Junine Toy, Paul Sereda, Rolando Barrios, Julio S G Montaner, Viviane D Lima
The SARS-CoV-2 (COVID-19) pandemic has impacted the care of people living with HIV (PLWH). This study aims to characterize the impact of the pandemic on the length of HIV treatment gap lengths and viral loads among people living with HIV (PLWH) in British Columbia (BC), Canada, with a focus on Downtown Eastside (DTES), which is one of the most impoverished neighbourhoods in Canada. We analyzed data from the HIV/AIDS Drug Treatment Program from January 2019 to February 2022. The study had three phases: Pre-COVID, Early-COVID, and Late-COVID...
April 29, 2024: Social Science & Medicine
#25
JOURNAL ARTICLE
Arisha Khoso, Abrar Hussain, Marium Rehman, Saira Akram, Diyar Ahmad, Hassan Bin-Asif, Sindhu Zahid, Khwaja Ali Hasan, Syed Abid Ali
Enterococcus has emerged as an opportunistic pathogen because of its antibiotic resistance and virulence profile, which makes it a causative agent of several diseases like endocarditis, surgical site, and urinary tract infections. Currently, species of this genus are the 2nd most frequently isolated microorganisms from hospital-acquired infections. Significant association with hospitals and unhygienic conditions of the environments has made them resistant to a wide range of antibiotics. On the brighter side, enterococci have the ability to produce antimicrobial proteins (i...
May 4, 2024: Probiotics and Antimicrobial Proteins
#26
JOURNAL ARTICLE
Zohreh Janbozorgi, Hasan Khalaji, Jalil Moradi
BACKGROUND: children with Intellectual Disabilities (ID) are less proficient in motor skills compared to normally developing children, which means they need more time for learning skills. In this context, the purpose of this research is to investigate the effect of the Brailletonik physical activity program (BPAM) on the balance and reaction time of children with ID. METHODS: The statistical sample is consisted of 30 children aged 8 to 12 (21 boys, 9 girls) with ID with an average age of 9...
May 3, 2024: BMC Sports Science, Medicine and Rehabilitation
#27
COMPARATIVE STUDY
Bilge Karcı, Hasan Basri Savas
BACKGROUND: This study aimed to assess and compare the concentrations of growth factors, white blood cells (WBCs), and platelets in injectable platelet-rich fibrin (i-PRF) derived from people with healthy periodontal conditions and those with chronic periodontitis. METHODS: Venous blood samples were obtained from 30 patients diagnosed with chronic periodontitis (test group) and 30 participants with healthy periodontal conditions (control group). The i-PRF was then acquired from centrifuged blood...
May 3, 2024: BMC Oral Health
#28
JOURNAL ARTICLE
Kelsi M Chesney, Gregory F Keating, Nirali Patel, Lindsay Kilburn, Adriana Fonseca, Cheng-Chia Wu, Javad Nazarian, Roger J Packer, Daniel A Donoho, Chima Oluigbo, John S Myseros, Robert F Keating, Hasan R Syed
INTRODUCTION: Focused ultrasound (FUS) is an innovative and emerging technology for the treatment of adult and pediatric brain tumors and illustrates the intersection of various specialized fields, including neurosurgery, neuro-oncology, radiation oncology, and biomedical engineering. OBJECTIVE: The authors provide a comprehensive overview of the application and implications of FUS in treating pediatric brain tumors, with a special focus on pediatric low-grade gliomas (pLGGs) and the evolving landscape of this technology and its clinical utility...
May 3, 2024: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
#29
REVIEW
Taha Teaima, Rohan Gajjar, Vivek Jha, Imran Aziz, Sami Shoura, Abdul-Rahim Shilbayeh, Naim Battikh, Hasan Sqour, Javier Gomez-Valencia
Right ventricular dysfunction (RVD) continues to be a significant contributor to both mortality and morbidity, posing a significant challenge in the management of patients undergoing evaluation for mechanical circulatory support (MCS). Currently, there is a paucity of data regarding outcomes in this subset of patients. We analyzed the National Inpatient Sample database (NIS) to identify adult hospitalizations who underwent intra-aortic balloon pump (IABP) placement with or without co-existence of RVD. Multivariate logistic regression, and linear regression analyses were used to compare outcomes, and adjust for possible confounders...
May 1, 2024: Current Problems in Cardiology
#30
Wessam Taifour, Hasan Youssef, Yahia Ranjous, Ali Deeb, Aimar Khir Abo Moughdeb
INTRODUCTION AND IMPORTANCE: Drainage tubes are commonly used to remove unwanted fluid after surgery. However, they are not indicated in all situations, and there is no evidence to support their common utilization. CASE PRESENTATION: A 31-year-old woman at 38 weeks of gestation with a history of five cesarean sections presented with lower abdominal pain following a tonic-clonic epileptic seizure. Emergency surgery was performed due to fetal distress, and the uterus was found to be ruptured...
April 23, 2024: International Journal of Surgery Case Reports
#31
JOURNAL ARTICLE
Mohammed Alrouji, Sabina Yasmin, Mohammad Furkan, Fahad A Alhumaydhi, Sharaf E Sharaf, Rizwan Hasan Khan, Anas Shamsi
BACKGROUND: Neurodegeneration is a term describing an irreversible process of neuronal damage. In recent decades, research efforts have been directed towards deepening our knowledge of numerous neurodegenerative disorders, with a particular focus on conditions such as Alzheimer's disease (AD). Human transferrin (htf) is a key player in maintaining iron homeostasis within brain cells. Any disturbance in this equilibrium gives rise to the emergence of neurodegenerative diseases and associated pathologies, particularly AD...
2024: Journal of Alzheimer's Disease: JAD
#32
JOURNAL ARTICLE
Hasan Hadzalic, Daniel Fritschi, Oliver Gaemperli, Luca Oechslin
No abstract text is available yet for this article.
May 3, 2024: International Journal of Cardiovascular Imaging
#33
JOURNAL ARTICLE
Hanif 'Izzuddin Zakly, Siti Zulaikah, Cahyo Aji Hapsoro, Shofi Maulida, Muhammad Fathur Rouf Hasan
Mount Arjuno-Welirang has a geological structure consisting of volcanic breccia, lava, tufan breccia, and tuff. This research focuses on exploring the chemical content of Arjuno-Welirang igneous rocks. The mapping of chemical element content is carried out to provide information on the distribution of Arjuno-Welirang dominant elements which are very important for exploitation and industry. The results of X-ray fluorescence (XRF) analysis of seven igneous rock samples showed that there were Al, Si, P, K, Ca, Ti, V, Cr, Mn, Fe, Cu, Zn, Sr, Ba, Eu, and Re...
May 3, 2024: Environmental Science and Pollution Research International
#34
JOURNAL ARTICLE
Monira Rahman, Taniya Sultana, Md Morshedur Rahman, Naim Siddique, Golam Mahbub Faisal, Mehedi Mahmudul Hasan, Ziban Chandra Das, A N M Aminoor Rahman, Tofazzal Islam, M Nazmul Hoque
We performed whole-genome sequencing of four multidrug-resistant Enterococcus avium strains isolated from milk (4M1), feces (4F1 and 4F2), and farm soil (4S1) of mastitic dairy cows. The draft genomes of E. avium strains 4M1, 4F1, 4F2, and 4S1 were approximately 4.2 Mbp, with 39.1% GC content and 66.5× coverage.
May 3, 2024: Microbiology Resource Announcements
#35
JOURNAL ARTICLE
Ozden Melis Durmaz Yilmaz, Murat Tasyurek, Hasan Onder Gumus
AIM: The purpose of this study is to develop software at a low cost that enables the detection of tooth colors by capturing photographs using various devices, and to compare its effectiveness with existing expensive methods. MATERIAL AND METHODS: A total of 60 anterior central incisor teeth from 30 individuals were included in the study. The CIELAB values (L,a,b) of each tooth were measured using a spectrophotometer, which is considered the gold standard. Subsequently, photographs of the teeth were taken using four different smartphones (iPhone- Xiaomi) and one digital camera (Canon)...
May 3, 2024: International Journal of Computerized Dentistry
#36
JOURNAL ARTICLE
Irsan Hasan, Ignatia Sinta Murti, Putut Bayupurnama, Kemal Fariz Kalista, Christina Hill-Zabala, Dennis Kananda, Elisabet Viayna
BACKGROUND: Human albumin (HA) is an effective adjuvant treatment for patients with cirrhosis developing spontaneous bacterial peritonitis (SBP), hepatorenal syndrome (HRS) and ascites requiring large-volume paracentesis (LVP). However, cost remains a barrier to use, particularly in resource-limited settings. This study aims to assess the cost-effectiveness of HA in patients with cirrhosis with SBP, HRS or ascites requiring LVP in the Indonesian healthcare system as a representative of a resource-limited setting...
2024: Drugs in Context
#37
REVIEW
Khandoker Shahjahan Alam, A M A Daiyan Kaif, Sajal K Das, Sarafat H Abhi, S M Muyeen, Md Firoj Ali, Zinat Tasneem, Md Manirul Islam, Md Robiul Islam, Md Faisal R Badal, Md Hafiz Ahamed, Subrata K Sarker, Prangon Das, Md Mehedi Hasan
The global need for energy is increasing at a high rate and is expected to double or increase by 50%, according to some studies, in 30 years. As a result, it is essential to look into alternative methods of producing power. Solar photovoltaic (PV) power plants utilize the sun's clean energy, but they're not always dependable since they depend on weather patterns and requires vast amount of land. Space-based solar power (SBSP) has emerged as the potential solution to this issue. SBSP can provide 24/7 baseload carbon-free electricity with power density over 10 times greater than terrestrial alternatives while requiring far less land...
May 15, 2024: Heliyon
#38
JOURNAL ARTICLE
Iqra Subhan, Yasir Hasan Siddique
Rotenone is a naturally occurring plant product used as an insecticide, pesticide and piscicide. It is lipophilic in nature and can cross the blood-brain barrier and induce the degeneration of neurons. It inhibits the mitochondrial respiratory chain complex I and stops the transfer of electrons. It induces ROS generation, which impairs mitochondrial activity. Rotenone is a toxic agent which causes the death of neurons. The present review describes the effect of rotenone on neurodegeneration with an emphasis on behavioral, pathological and neuropathological components carried out on various experimental models such as cell lines, Drosophila melanogaster, mice and rats...
May 2, 2024: Current Drug Targets
#39
JOURNAL ARTICLE
Nathalie A Lengacher, Julianna J Tomlinson, Ann-Kristin Jochum, Jonas Franz, Omar Hasan Ali, Lukas Flatz, Wolfram Jochum, Josef Penninger, Christine Stadelmann, John M Woulfe, Michael G Schlossmacher
The majority of patients with Parkinson disease (PD) experience a loss in their sense of smell and accumulate insoluble α-synuclein aggregates in their olfactory bulbs (OB). Subjects affected by a SARS-CoV-2-linked illness (COVID-19) also frequently experience hyposmia. We previously postulated that microglial activation as well as α-synuclein and tau misprocessing can occur during host responses following microbial encounters. Using semiquantitative measurements of immunohistochemical signals, we examined OB and olfactory tract specimens collected serially at autopsies between 2020 and 2023...
May 3, 2024: Acta Neuropathologica Communications
#40
JOURNAL ARTICLE
Yaseen M Arabi, Hasan M Al-Dorzi, Omar Aldibaasi, Musharaf Sadat, Jesna Jose, Dina Muharib, Haifa Algethamy, Abdulrahman A Al-Fares, Fahad Al-Hameed, Ahmed Mady, Ayman Kharaba, Ali Al Bshabshe, Khalid Maghrabi, Khalid AlGhamdi, Ghulam Rasool, Adnan AlGhamdi, Ghaleb A Almekhlafi, Jamal Chalabi, Haifaa Ibrahim AlHumedi, Maram Hasan Sakkijha, Norah Khalid Alamrey, Amjad Sami Alaskar, Rabeah Hamad Alhutail, Kaouthar Sifaoui, Rakan Alqahtani, Ahmad S Qureshi, Mohammed Moneer Hejazi, Hatim Arishi, Samah AlQahtani, Amro Mohamed Ghazi, Saleh T Baaziz, Abeer Othman Azhar, Sara Fahad Alabbas, Mohammed AlAqeely, Ohoud AlOrabi, Aliaa Al-Mutawa, Maha AlOtaibi, Madiha Fawazy Elghannam, Mohammed Almaani, Sarah Fadel Buabbas, Wadiah Alawi M Alfilfil, Mohammed S Alshahrani, Joel Starkopf, Jean-Charles Preiser, Anders Perner, Jumana Hani AlMubarak, Wafa Mansoor Hazem, Talal Albrahim, Abdulaziz Al-Dawood
BACKGROUND: The optimal amount and timing of protein intake in critically ill patients are unknown. REPLENISH (Replacing Protein via Enteral Nutrition in a Stepwise Approach in Critically Ill Patients) trial evaluates whether supplemental enteral protein added to standard enteral nutrition to achieve a high amount of enteral protein given from ICU day five until ICU discharge or ICU day 90 as compared to no supplemental enteral protein to achieve a moderate amount of enteral protein would reduce all-cause 90-day mortality in adult critically ill mechanically ventilated patients...
May 2, 2024: Trials
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