Carolina Khosrawipour, Jakub Nicpoń, Zdzisław Kiełbowicz, Przemysław Prządka, Bartłomiej Liszka, Kacper Zielinski, Veria Khosrawipour, Shiri Li, Hien Lau, Joanna Kulas, Agata Diakun, Wojciech Kielan, Agata Mikolajczk-Martinez, Mariusz Chabowski
BACKGROUND: For decades, both intraperitoneal and pleural chemotherapy (IPC) have been delivered as a liquid solution. Recent studies suggest that foam carriers outperform liquid carriers for locoregional chemotherapy. For the first time, this study aims to evaluate the feasibility, safety, and characteristics of foam-based intrathoracic chemotherapy (FBiTC) in an in vivo setting. METHODS: In this study, contrast-enhanced FBiTC with doxorubicin was delivered via video-assisted thoracoscopy (VAT) in three swine under general anesthesia...
December 27, 2023: Pharmaceuticals